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| 1 | Myxedema ascites with high CA-125:Case and a review of literature显示文摘Ascites appearing in a previously healthy female patient is usually ascribed to a variety of causes,among which,is a cancerous process,especially if it comes with a raised CA-125 level.Although the CA-125 antigen is present on more than 80% of malignant epithelial ovarian tissue of non-mucinous type,it is also found on both healthy and malignant cells of mesothelial and non-mesothelial origin.Myxedema ascites which is caused by hypothyroidism is a rare entity,but on the other hand is easy to treat.It is one of the differential diagnoses when the ascites is refractory to treatment and no other obvious cause can be identified.If the diagnosis is delayed,patients will frequently receive unnecessary procedures,while treatment has very good response rates and ascites resolve with serum CA-125 normalization after adequate hormonal treatment. | Bou Khalil Roula El Rassi Patrick Chammas Nizar Obeid Jean Ghabach Maroun Sakr Charles Itani Tarek Farhat Said | 2013 | World Journal of Hepatology2013，5，2： | 4 |
| 2 | Phlebotomus papatasi and Meriones libycus as the vector and reservoir host of cutaneous leishmaniasis in Qomrood District,Qom Province,central Iran显示文摘Objective:To determine the sand flies species responsible for most transmission of Leishmania major(L major) to human,as well as to determine the main reservoir hosts of the disease. Methods:Sand flies were collected using sticky papers and mounted in Puri’s medium for species identification.Rodents were trapped by live Sherman traps.Both sand flies and rodents were subjected to molecular methods for detection of leishmanial parasite.Results:Phlebotomus papatasi(P.papatasi) was the common species in outdoor and indoor resting places.Employing PCR technique only three specimens of 150 P.papatasi(2%) were found naturally infected by parasites with a band of 350 bp which is equal to the L major parasite.Forty six rodents were captured by Sherman traps and identified.Microscopic investigation on blood smear of the animals for amastigote parasites revealed 1(3.22%) infected Meriones libycus(M.libycus). Infection of this animal to L.major was confirmed by PCR against rDNA loci of the parasite. Conclusions:This is the first molecular report of parasite infection of both vector(P.papatasi) and reservoir(M.libycus) to L major in the region.The results indicated that P.papatasi was the primary vector of the disease and circulating the parasite between human and reservoirs and M. libycus was the most important host reservoir for maintenance of the parasite source in the area. | Rassi Yavar Saghafipour Abedin Abai Mohammad Reza Oshaghi Mohammad Ali Rafizadeh Sina Mohebail Mehdi Yaaghobi-Ershadi Mohammad Reza Mohtarami Fatemeh Farzinnia Babak | 2011 | Asian Pacific Journal of Tropical Medicine2011，4，2： | 3 |
| 3 | Optimum chemotherapy for the management of advanced biliary tract cancer显示文摘Biliary tract cancers(BTCs) are highly fatal malignancies, which are often diagnosed at an advanced stage and have relatively poor prognosis.The treatment of patients with advanced BTC is systemic, based on chemotherapy or best supportive care, depending on their performance status.Despite clinical trials studyingmany chemotherapeutic regimens and targeted therapies for the treatment of BTC, the standard of care for advanced BTC remains the combination of gemcitabine with cisplatin.Many new molecules targeting proliferation and survival pathways, the immune response and angiogenesis are currently undergoing phase Ⅰ and Ⅱ trials for the treatment of advanced BTC with promising results. | Marwan Ghosn Hampig Raphael Kourie Elie El Rassy Ralph Chebib Fadi El Karak Colette Hanna Dolly Nasr | 2015 | World Journal of Gastroenterology2015，21，14： | 2 |
| 4 | Where does chemotherapy stands in the treatment of ampullary carcinoma? A review of literature显示文摘Ampullary carcinoma(AC) is a rare gastrointestinal tumor without clear treatment recommendations.The management of this tumor is usually extrapolated from the treatment of pancreatic,biliary duct and intestinal cancers.Few papers have studied the AC as an independent entity and yet succombs to several limitations.These studies were retrospective single institutional experiences with limited sample sizes recruited over a long period of time.Unlike metastatic ACs where chemotherapy is the only recommended option,localized AC once excised may be approached by either chemotherapy alone or concomitant chemoradiation therapy.In this review,we report the overall survival and recurrence factors of more than 1000 patients from all the studies treating exclusively ACs.We also review the medical treatment of this tumor and conclude to the necessity of multi-institutional randomized controlled studies for AC exclusively. | Marwan Ghosn Hampig Raphael Kourie Elie El Rassy Fady Ghassan Haddad Colette Hanna Fadi El Karak Dolly Nasr | 2016 | World Journal of Gastrointestinal Oncology2016，8，10： | 2 |
| 5 | Dilemma of first line regimens in metastatic pancreatic adenocarcinoma显示文摘Pancreatic cancer is one of the deadliest cancers,ranking fourth among cancer-related deaths. Despite all the major molecular advances and treatment breakthroughs, mainly targeted therapies, the cornerstone treatment of metastatic pancreatic cancer(m PC) remains cytotoxic chemotherapy. In 2016, more than 40 years after the introduction of gemcitabine in the management of m PC, the best choice for first-line treatment has not yet been fully elucidated. Two main strategies have been adopted to enhance treatment efficacy. The first strategy is based on combining non-cross resistant drugs, while the second option includes the development of newer generations of chemotherapy. More recently, two new regimens, FOLFIRINOX and gemcitabine/nab-paclitaxel(GNP), have both been shown to improve overall survival in comparison with gemcitabine alone, at the cost of increased toxicity. Therefore, the best choice for first line therapy is a matter of debate. For some authors, FOLFIRINOX should be the first choice in patients with an Eastern Cooperative Oncology Group score(0-1) given its lower hazard ratio. However, others do not share this opinion. In this paper, we review the main comparison points between FOLFIRINOX and GNP. We analyze the two pivotal trials to determine the similarities and differences in study design. In addition, we compare the toxicity profile of the two regimens as well as the impact on quality of life. Finally, we present studies revealing real life experiences and review the advantages and disadvantages of possible second-line therapies including their cost effectiveness. | Marwan Ghosn Tony Ibrahim Tarek Assi Elie El Rassy Hampig Raphael Kourie Joseph Kattan | 2016 | World Journal of Gastroenterology2016，22，46： | 2 |
| 6 | Development of species-specific PCR and PCR-restriction fragment length polymorphism assays for L. infantum / L. donovani discrimination显示文摘 | Mohammad A. Oshaghi Naseh Maleki Ravasan Mallorie Hide Ezat-Aldin Javadian Yavar Rassi Mohammad M. Sedaghat Mehdi Mohebali Homa Hajjaran | 2009 | Experimental Parasitology2009，，1： | 2 |
| 7 | Chagas disease显示文摘 | Anis Rassi Anis Rassi José Antonio Marin-Neto | 2010 | The Lancet . 2010 (9723)2010，，： | 2 |
| 8 | Traumatic myiasis agents in Iran with introducing of new dominant species,Wohlfahrtia magnifica(Diptera:Sarcophagidae)显示文摘Objective:To study agents of animal wound myiasis in various geographical districts of Fars province.Methods:This study has been done in Fars province,located in the southern part of Iran.Sums of 10358 domestic animals have been visited from April 2011 to March 2012.The infected wounds in any parts of animal body were sampled by means of forceps.Results:About 61%of all animal wound myiasis were caused by larvae of Wohlfahrtia magnifica.The most wound myiasis cases due to this species occurred in central part of Fars province.There wasn't any significant difference between sheep and goat in infestation with myiasis(P>0.05).The infestation rate of myiasis in cattle community was 0.86%.Conclusions:The infestation rate of livestock was lower than other works in Iran and some other countries like Saudi Arabia.Chrysomya bezziana has been mentioned as main myiasis agent in Iran.But in this study it cleared that similarly to some European countries,the common animal myiasis agent in Iran is Wohlfahrtia tnagnifica.Introducing new species as principal agent for myiasis can help public health and animal husbandry policy makers to prepare sufficient and effective control and/or preventive measures for this disease. | Javad Rafinejad Kamran Akbarzadeh Yavar Rassi Jamasp Nozari Mohammad Mehdi Sedaghat Mostafa Hosseini Hamzeh Alipour Abdolmajid Ranjbar Danial Zeinali | 2014 | Asian Pacific Journal of Tropical Biomedicine2014，4，6： | 2 |
| 9 | Capillary zone electrophoresis of linear and branched oligosaccharides显示文摘 | Nashabeh W Rassi ZE | 1992 | JChromatogr1992，600，： | 1 |
| 10 | Renal artery pseudoaneurysm after blunt abdominal trauma 显示文摘 | Jebare V A E1 Rassi I Achouh P E | 1998 | J Vasc Surg1998，27，： | 1 |
| 11 | Chagas disease显示文摘 | Rassi A Jr Rassi A Marin-Neto JA | | 0，，9723： | 1 |
| 12 | Primary isolated chronicchylopericardium 显示文摘 | Sleilaty G Rassi I Alawi A | 2002 | Interact Cardiovasc Thorac Surg2002，1，2： | 1 |
| 13 | Benefit of early invasive therapy in acute coronary syndromes: a meta-analysis of contemporary randomized clinical trials 显示文摘 | Barry A A Kumbhani D J Rassi A N | 2006 | J Am Coil Cardiol2006，48，7： | 1 |
| 14 | American trypanosomiasis(Chagas disease) 显示文摘 | Rassi A J Rassi A Rezende J M | 2012 | Infect Dis Clin N Am2012，26，： | 1 |
| 15 | Tropical fruit pulps decreased probiotie survival to in vitro gastrointestinal stress in synbiotic soy yoghurt with okara during storage 显示文摘 | Bedani R Vieira ADS Rassi EA et at | 2014 | LWT Food Sci Technol2014，55，2： | 1 |
| 16 | Sensitivity and specificity of cerebrospinal fluid flow cytometry for the diagnosis of leukemic meningitis in acute lymphoblastic leukemia/lymphoma显示文摘 | Mitri Z Siddiqui MT E1 Rassi F | 2014 | Leukemia & Lymphoma2014，55，7： | 1 |
| 17 | Cochleovestibular Impairment in Pediatric Cogan's Syndrome 显示文摘 | Ndiaye IC Rassi S J Wiener-Vacher SR | 2002 | Pediatrics2002，109，2： | 1 |
| 18 | Phlebotomus perfiliewi transcaucasicus is circulating both Leishmania donovani and L. infantum in northwest Iran显示文摘 | Mohammad Ali Oshaghi Naseh Maleki Ravasan Mallorie Hide Ezat-Aldin Javadian Yavar Rassi Javid Sadraei Mehdi Mohebali Mohammad Mehdi Sedaghat Homa Hajjaran Zabiholah Zarei Fatemeh Mohtarami | 2009 | Experimental Parasitology2009，，3： | 1 |
| 19 | NMR and IR spectroscopy of silica aerogels with different hydrophobic characteristics 显示文摘 | RASSY H E PIERRE A C | 2005 | Non-Cryst Solids2005，351，16： | 1 |
| 20 | Down-regulation of osteoclast differentiation by daidzein via caspase 3显示文摘 | Lieberherr M Chaumaz G etal | 2002 | J Bone Miner Res2002，17，4： | 1 |
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