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| 1 | Catatonia:Our current understanding of its diagnosis, treatment and pathophysiology显示文摘Catatonia is a psychomotor syndrome that has been reported to occur in more than 10% of patients with acute psychiatric illnesses. Two subtypes of the syndrome have been identified. Catatonia of the retarded type is characterized by immobility, mutism, staring, rigidity, and a host of other clinical signs. Excited catatonia is a less common presentation in which patients develop prolonged periods of psychomotor agitation. Once thought to be a subtype of schizophrenia, catatonia is now recognized to occur with a broad spectrum of medical and psychiatric illnesses, particularly affective disorders. In many cases, the catatonia must be treated before any underlying conditions can be accurately diagnosed. Most patients with the syndrome respond rapidly to low-dose benzodiazepines, but electroconvulsive therapy is occasionally required. Patients with longstanding catatonia or a diagnosis of schizophrenia may be less likely to respond. The pathobiology of catatonia is poorly understood, although abnormalities in gamma-aminobutyric acid and glutamate signaling have been suggested as causative factors. Because catatonia is common, highly treatable, and associated with significant morbidity and mortality if left untreated, physicians should maintain a high level of suspicion for this complex clinical syndrome. Since 1989, we have systematically assessed patients presenting to our psychiatry service with signs of retarded catatonia. In this paper, we present a review of the current literature on catatonia along with findings from the 220 cases we have assessed and treated. | Sean A Rasmussen Michael F Mazurek Patricia I Rosebush | 2016 | World Journal of Psychiatry2016,6,4: | 7 |
| 2 | Elevated pro-inflammatory and lipotoxic mucosal lipids characterise irritable bowel syndrome显示文摘AIM:To investigate the pathophysiology of irritable bowel syndrome(IBS)by comparing the global mucosal metabolic profiles of IBS patients with those of healthy controls.METHODS:Fifteen IBS patients fulfilling the Rome Ⅱcriteria,and nine healthy volunteers were included in the study.A combined lipidomics(UPLC/MS)and metabolomics(GC×GC-TOF)approach was used to achieve global metabolic profiles of mucosal biopsies from the ascending colon.RESULTS:Overall,lipid levels were elevated in patients with IBS.The most significant upregulation was seen for pro-inflammatory lysophosphatidylcholines.Other lipid groups that were significantly upregulated in IBS patients were lipotoxic ceramides,glycosphingolipids,and di-and triacylglycerols.Among the metabolites,the cyclic ester 2(3H)-furanone was almost 14-fold upregulated in IBS patients compared to healthy subjects(P=0.03).CONCLUSION:IBS mucosa is characterised by a distinct pro-inflammatory and lipotoxic metabolic profile.Especially,there was an increase in several lipid species such as lysophospholipids and ceramides. | Kajsa Kajander Eveliina Myllyluoma Sinikka Kyrnpalo Martin Rasmussen Pentti Sipponen Ismo Mattila Tuulikki Seppnen-Laakso Heikki Vapaatalo Matej Orei Riitta Korpela | 2009 | World Journal of Gastroenterology2009,15,48: | 5 |
| 3 | Integrative taxonomy of the Russet Bush Warbler Locustella mandelli complex reveals a new species from central China显示文摘Background: The Russet Bush Warbler Locustella(previously Bradypterus) mandelli complex occurs in mountains in the eastern Himalayas, southern China, Vietnam, the Philippines, and Indonesia. The taxonomy has been debated,with one(L. seebohmi) to four(L. seebohmi, L. mandelli, L. montis and L. timorensis) species having been recognised.Methods: We used an integrative approach, incorporating analyses of morphology, vocalizations and a molecular marker, to re-evaluate species limits in the L. mandelli complex.Results: We found that central Chinese L. mandelli differed from those from India through northern Southeast Asia to southeast China in plumage, morphometrics and song. All were easily classified by song, and(wing + culmen)/tail ratio overlapped only marginally. Both groups were reciprocally monophyletic in a mitochondrial cytochrome b(cytb) gene tree, with a mean divergence of 1.0 ± 0.2%. They were sympatric and mostly altitudinally segregated in the breeding season in southern Sichuan province. We found that the Mt Victoria(western Myanmar) population differed vocally from other L. mandelli, but no specimens are available. Taiwan Bush Warbler L. alishanensis was sister to the L. mandelli complex, with the most divergent song. Plumage, vocal and cytb evidence supported the distinctness of the south Vietnamese L. mandelli idonea. The Timor Bush Warbler L. timorensis, Javan Bush Warbler L.montis and Benguet Bush Warbler L. seebohmi differed distinctly in plumage, but among-population song variation in L. montis exceeded the differences between some populations of these taxa, and mean pairwise cytb divergences were only 0.5–0.9%. We also found that some L. montis populations differed morphologically.Conclusions: We conclude that the central Chinese population of Russet Bush Warbler represents a new species,which we describe herein, breeding at mid elevations in Sichuan, Shaanxi, Hubei, Hunan and Guizhou provinces.The taxonomic status of the other allopatric populations is less clear. However, as they differ to a degree comparable with that of the sympatric L. mandelli and the new species, we elevate L. idonea to species status, and retain L. seebohmi and L. montis as separate species, the latter with timorensis as a subspecies. Further research should focus on different populations of L. montis and the Mt Victoria population of L. mandelli. | Per Alstrom Canwei Xia Pamela C Rasmussen Urban Olsson Bo Dai Jian Zhao Paul J Leader Geoff J Carey Lu Dong Tianlong Cai Paul I Holt Hung Le Manh Gang Song Yang Liu Yanyun Zhang Fumin Lei | 2015 | Chinese Birds2015,,2: | 4 |
| 4 | 卒中介入治疗培训指南:国际多学会共识文件显示文摘1背景
缺血性卒中是全球人口死亡和残疾的首要原因。很多急性大血管闭塞(emergent large vesselocclusion,ELVO)患者都会遗留长期残疾。事实上,这些颅内大动脉闭塞经常会导致大面积脑损伤,进而造成患者死亡或严重致残。 | Lavine SD Cockroft K Hoh B Bambakidis N Khalessi AA Woo H Riina H Siddiqui A Hirsch JA Chong W Rice H Wenderoth J Mitchell P Coulthard A Signh TJ Phatorous C Khangure M Klurfan P ter Brugge K Iancu D Gunnarsson T Pongpech S Rodesch G Soderman M Taylor A Krings T Orbach D Picard L Suh DC Zheng HQ Jansen O Muto M Szikora I Pierot L Brouwer P Gralla J Renowden S Andersson T Fiehler J Turjman F White P Januel AC Spelle L Kulcsar Z Chapot R Biondi A Dima S Taschner C Szajner M Krajina A Sakai N Matsumaru Y Yoshknura S Ezura M Fujinaka T Iihara K Ishii A Higashi T Hirohata M Hyodo A Ito Y Kawanishi M Kiyosue H Kobayashi E Kobayashi S Kuwayama N Matsumoto Y Miyachi S Murayama Y Nagata I Nakahara I Nemoto S Niimi Y Oishi H Satomi J Satow T Sugiu K Tanaka M Terada T Yamagami H Diaz O Lylyk P Jayaraman MV Patsalides A Gandhi CD Lee SK Abruzzo T Albani B Ansari SA Arthur AS Baxter BW Bulsara KR Chen M Almandoz JE Fraser JF Heck DV Hetts SW Hussain MS Klucznik RP Leslie-Mawzi TM Mack WJ McTaggart RA Meyers PM Mocco J Prestigiacomo CA Pride GL Rasmussen PA Starke RM Sunenshine PJ Tarr RW Frei DF Pabo M Nogueira RG Zaidat OO Jovin T Linfante I Yavagal D Liebeskind D Novakovic R Pongpech S 许岩 孙瑞 郭芮兵 | 2017 | 国际脑血管病杂志2017,25,5: | 2 |
| 5 | Field weed population dynamics:a review of model approaches and applications显示文摘 | Holst N Rasmussen I A Bastiaans L | 2007 | Weed Research2007,47,: | 1 |
| 6 | Evaluation of MODIS/LAI, fAPAR and the relation between fAPAR and NDVI in a semi-arid environment using in situ measurements显示文摘 | Fensholt R Sandholt I Schultz Rasmussen M | 2004 | Remote Sensing of Environment2004,91,: | 1 |
| 7 | Ehlers-Danlos syndrome type Ⅳ and a novel mutation of the type Ⅲ procollagen gene as a cause of abdominal apoplexy显示文摘 | Hassan I Rasmussen TE Schwarze U | 2002 | Mayo Clin Proc2002,77,8: | 1 |
| 8 | A simple interpretation of the surface temperature/vegetation index space for assessment of surface moisture status 显示文摘 | Sandholt I Rasmussen K Andersen J | | Remote Sensing Of Environment0,,79: | 1 |
| 9 | A Myeobac- terium tuber-culosis operon encoding ESAT-6 and a novel low- molecular-mass culture filtrate protein(CFP-lO) 显示文摘 | Berthet FX Rasmussen PB Roesnkrands I | 1998 | Microbiol- ogy1998,144,11: | 1 |
| 10 | Diffusion axonal injury in severe traumatic brain injury visualized using high-resolution diffusion tensor imaging显示文摘 | Xu J Rasmussen I A Lagopoulos J | 2007 | Neurotrauma2007,24,5: | 1 |
| 11 | Localization of thymosin β10 in breast cancer cells: relationship to actin cytoskeletal remodeling and cell motility显示文摘 | Maelan A E Rasmussen T K Larsson L I | 2007 | Histochem Cell Biol2007,127,: | 1 |
| 12 | A simple interpretation of the surface temperature/vegetation index space for assessment of surface moisture status显示文摘 | Sandholt I Rasmussen K Andersen J | 2002 | Remote Sensing of Environment2002,79,23: | 1 |
| 13 | SHRIMP Uranium-lead Dating of Diagenetic Xenotime in Silicialastic Rocks显示文摘 | MCNAUGHTON N J RASMUSSEN B FLETCH- ER I R | 1999 | Science1999,285,: | 1 |
| 14 | Mycotox-ins in silage显示文摘 | Storm I D M Srensen J L Rasmussen R R | 2008 | Stewart Postharvest Review2008,4,6: | 1 |
| 15 | Ventilatory pattern and associated episodic hypoxaemia in the late postoperative period in the general surgical ward显示文摘 | Rnsenberg J Rasmussen G I Wojdemann K R | 1999 | Anaesthesia1999,54,: | 1 |
| 16 | Coagulation activation after laparoscopic cholecystectomy in spite of thromboembolism prophylaxis 显示文摘 | Lindberg F Rasmussen I Siegbahm A | 2000 | Surg Endosc2000,14,9: | 1 |
| 17 | Synchronization of the NGRIP, GRIP, and GISP2 ice cores across MIS 2 and palaeoclimatic implications显示文摘 | Rasmussen S O Seierstad I K Andersen K K | 2008 | Quaternary Science Reviews2008,27,: | 1 |
| 18 | Starch determination in horticultural plant- material by an enzymat ic-coJorimetic procedure显示文摘 | Rasmussen T S Henry R I | 1990 | Journal of the Science of Food and Agriculture1990,52,2: | 1 |
| 19 | Multi-Mycotoxin Analysis of Maize Silage by LC-MS/MS显示文摘 | RASMUSSEN R R STORM I M L D RASMUSSEN P H | 2010 | Analytical and Bioanalytical Chemistry2010,397,2: | 1 |
| 20 | Current use of thrumboembohsm prophylaxis for iaparoscopic cholecystectomy patients in Sweden显示文摘 | Bjorek M Rasmussen I | 2005 | surg Endese2005,19,3: | 1 |