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| 1 | Advances in alcoholic liver disease:An update on alcoholic hepatitis显示文摘Alcoholic hepatitis is a pro-inflammatory chronic liver disease that is associated with high short-term morbidity and mortality(25%-35% in one month) in the setting of chronic alcohol use. Histopathology is notable for micro- and macrovesicular steatosis, acute inflammation with neutrophil infiltration, hepatocellular necrosis, perivenular and perisinusoidal fibrosis, and Mallory hyaline bodies found in ballooned hepatocytes. Other findings include the characteristic eosinophilic fibrillar material(Mallory's hyaline bodies) found in ballooned hepatocytes. The presence of focal intense lobular infiltration of neutrophils is what typically distinguishes alcoholic hepatitis from other forms of hepatitis, in which the inflammatory infiltrate is primarily composed of mononuclear cells. Management consists of a multidisciplinary approach including alcohol cessation, fluid and electrolyte correction, treatment of alcohol withdrawal, and pharmacological therapy based on the severity of the disease. Pharmacological treatment for severe alcoholic hepatitis, as defined by Maddrey's discriminant factor ≥ 32, consists of either prednisolone or pentoxifylline for a period of four weeks. The body of evidence for corticosteroids has been greater than pentoxifylline, although there are higher risks of complications. Recently head-to-head trials between corticosteroids and pentoxifylline have been performed, which again suggests that corticosteroids should strongly be considered over pentoxifylline. | Randy Liang Andy Liu Ryan B Perumpail Robert J Wong Aijaz Ahmed | 2015 | World Journal of Gastroenterology2015，21，42： | 5 |
| 2 | N-acyl-L-homoserine lactones: a class of bacterial quorum-sensing signals alter post-embryonic root de- velopment in Arabidopsis thaliana 显示文摘 | Randy O C Mignel M T Jose L B | 2008 | Plant Cell Environ2008，31，： | 1 |
| 3 | Vaginal replacement in the pediatric age group:a 34-year experience of intestinal vaginoplasty in children and young girls显示文摘 | LIMA M RUGGERI G RANDI B | 2010 | J Pediatr Surg2010，45，10： | 1 |
| 4 | Exploring process data with the use of robust outlier detection algorithms显示文摘 | LEO H C RANDY J P MARY B S | 2003 | Journal of Process Control2003，，13： | 1 |
| 5 | Views of Nature ofScience questionnaire:Toward Valid and Meaningful Assessmentof learners'Conceptions of Nature of Science显示文摘 | Norm G L Found A Randy L B | 2002 | Journal of Re-search in Science Teaching2002，39，6： | 1 |
| 6 | Large-scale dispersant leaching and effectiveness ex- periments with oils on calm water 显示文摘 | Alun Lewis A B Ken Trudel Randy C Belore | 2010 | Marine Pollution Bulletin2010，60，2： | 1 |
| 7 | Effects of air quality regu-lations on polluting industries显示文摘 | RANDY B HENDERSON V | 2000 | The Journal of Politi-cal Economy2000，18，2： | 1 |
| 8 | A new azimuthal deep reading resistivity tool for geosteering and advanced formation evaluation显示文摘 | Bittar M Klein J Randy B | 2009 | SPE Reservoir Evaluation&Engineering2009，122，： | 1 |
| 9 | Biophysical characterization of fungal phytase 显示文摘 | RANDY M B MICHAEL W R | 1998 | Appl Environ Microbiol1998，64，11： | 1 |
| 10 | Effects of image compression on iris recognition system performance显示文摘 | Robert W I Randy P B Lauren R K | 2008 | Journal of Electronic Imaging2008，17，01： | 1 |
| 11 | A new azimuthal deep reading resistivity tool for geosteering and advanced formation evaluation 显示文摘 | Bittar M Klein J Randy B | 2009 | SPE Reservoir Evaluation &Engineering2009，12，2： | 1 |
| 12 | Role of topical steroids in reducing dysfunction after nerve injury显示文摘 | Edgar B Galloway Ⅲ Randy LJ | 2000 | Laryngoscope2000，110，11： | 1 |
| 13 | Chemical and genetic characterization of bacteriocins : antimicrobial peptides for food safety 显示文摘 | Abigail B Snyder Randy W Worobo | 2014 | Society of Chemical Industry2014，94，： | 1 |
| 14 | Busse inflammation and asthma 显示文摘 | Randy J Horwitz William W B | 1995 | J Asthma1995，16，4： | 1 |
| 15 | Evidence-based medicine in pediatric residency programs:where are we now显示文摘 | Kersten H B Randis T M Giardino A P | 2005 | Ambul Pediatr2005，5，5： | 1 |
| 16 | Large-scale dispersant leaching and effectivenessexperiments with oils on calm water 显示文摘 | LEWIS ALUN KEN TRUDEL B BEL0RE RANDY C | 2010 | Marine Pollu-tion Bulletin2010，60，： | 1 |
| 17 | Payments for ecosystem services and poverty reduction: concepts, issues, and empirical perspectives显示文摘 | Erwinh B Leslie L Randy S | 2008 | Environment and Development Economics2008，13，3： | 1 |
| 18 | Molecular characterization and expression of a Phytase gene from the thermophilic fungus thermomyces lanuginosus显示文摘 | RANDY M B MICHAEL W R KIMBERLY M B | 2000 | App1 Environ Microbiol2000，64，： | 1 |
| 19 | Biophysical characterization of fungal phytase显示文摘 | MICHAEL W R | 1998 | Appl Environ Microbiol1998，64，11： | 1 |
| 20 | Blanua double 显示文摘 | Orbani'c A Pisanski T Randi'c M Servatius B | 2004 | Mathematical Communications2004，，9： | 1 |
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