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| 1 | Use of a novel covered self-expandable metal stent with an anti-migration system for endoscopic ultrasound-guided drainage of a pseudocyst显示文摘The development of pseudocysts in patients with chronic pancreatitis has been reported in 23%-60% of cases and drainage is indicated when they become symptomatic. Endoscopic ultrasound-guided drainage with the placement of plastic or metallic stents to create a cystogastric anastomosis has been shown to be a reliable and efficacious maneuver. Metallic stent use appears to be a safe and effective alternative that shortens the length of time of the procedure and maintains a greater diameter in the cystogastric communication. However, important migration rates have been reported. The use of new metallic stents that are specially designed to prevent migration represents a promising development in the treatment of these group of patients that appears to be safe and effective for pseudocyst drainage and could importantly reduce migrationrates, while at the same time having the advantage of a single step procedure and a larger fistula diameter in the endoscopic cystogastric anastomosis. | Félix Ignacio Téllez-vila lvaro Villalobos-Garita Miguel ngel Ramírez-Luna | 2013 | World Journal of Gastrointestinal Endoscopy2013，5，6： | 5 |
| 2 | 在与心肌的梗塞介绍的就医的病人的心率的预示的意义显示文摘 AIM: To investigate the prognostic significance of resting heart rate in patients with acute coronary syndrome (ACS), independent of other known factors. METHODS: Patients 40 years of age or older who had been admitted with acute coronary syndrome (ACS) to one of the 94 hospitals participating in the Prevalence of Peripheral Arterial Disease in Patients with Acute Coronary Syndrome (PAMISCA) study were included. Patients were divided into two groups based on their resting heart rate (HR ≥ or < 70 bpm). Complications were recording during a follow-up period of 1 year. RESULTS: There were 1054 ACS patients analyzed (43.5% with ST segment elevation and 56.5% without elevation). Mean age was 66.6 ± 11.7 years, 70.6% were male and 29.4% of subjects were female. During follow-up, more patients in the HR ≥ 70 bpm group were hospitalized for heart failure and they also had a higher mortality rate. In the multivariate analysis, a heart rate of ≥ 70 bpm was independently related to overall mortality during the follow-up period (hazard ratio 2.5; 95% confidence interval, 1.26-4.97, P = 0.009). CONCLUSION: A resting heart rate ≥ 70 bpm in patients who survive an ACS is an indicator of a high risk of suffering cardiovascular events during follow-up. | Lorenzo Fácila Pedro Morillas Juan Quiles Federico Soria Alberto Cordero Pilar Mazón Manuel Anguita Cándido Martín-Luengo Jose Ramón Gonzalez-Juanatey Vicente Bertomeu | 2012 | World Journal of Cardiology2012，4，1： | 3 |
| 3 | Should antibiotics be administered before arthroscopic knee surgery? A systematic review of the literature显示文摘AIM To explore the current evidence surrounding the administration of prophylactic antibiotics for arthroscopic knee surgery. METHODS Databases were searched from inception through May of 2018 for studies examining prophylactic antibiotic use and efficacy in knee arthroscopy. Studies with patient data were further assessed for types of arthroscopic procedures performed,number of patients in the study,use of antibiotics,and outcomes with the intention of performing a pooled analysis. Data pertaining to 'deep tissue infection' or 'septic arthritis' were included in our analysis. Reported data on superficial infection were not included in our data analysis. For the pooled analysis,a relative risk ratio was calculated and χ~2 tests were used to assess for statistical significance between rates of infection amongst the various patient groups. Post hoc power analyses were performed to compute the statistical power obtained from our sample sizes. Number needed to treat analyses were performed for statistically significant differences by dividing 1 by the difference between the infection rates of the antibiotic and no antibiotic groups. An alpha value of 0.05 was used for our analysis. Study heterogeneity was assessed by Cochrane's Q test as well as calculation of the I^2 value.RESULTS A total of 49682 patients who underwent knee ar-throscopy for a diverse set of procedures across 19 studies met inclusion critera for pooled analysis. For those not undergoing graft procedures,there were 27 cases of post-operative septic arthritis in 34487 patients(0.08%) who received prophylactic antibiotics and 16 cases in 10911(0.15%) who received none [risk ratio(RR) = 0.53,95% confidence interval(CI): 0.29-0.99,P = 0.05]. A sub-group analysis in which bony procedures were excluded was performed which found no significant difference in infection rates between patients that received prophylactic antibiotics and patients that did not(P > 0.05). All anterior cruciate ligament reconstruction studies used prophylactic antibiotics,but two studies investigating the effect of soaking the graft in vancomycin in addition to standard intravenous(IV) prophylaxis were combined for analysis. There were 19 cases in 1095 patients(1.74%) who received IV antibioitics alone and no infections in 2034 patients who received IV antibiotics and had a vancomycin soaked graft(RR = 0.01,95%CI: 0.001-0.229,P < 0.01).CONCLUSION Prophylactic antibiotics are effective in preventing septic arthritis following simple knee arthroscopy. In procedures involving graft implantation,graft soaking reduces the rate of infection. | John Carney Nathanael Heckmann Erik N Mayer Ram K Alluri Carleton Thomas Vangsness George F Hatch Ⅲ Alexander E Weber | 2018 | World Journal of Orthopedics2018，9，11： | 2 |
| 4 | Current trends of liver cirrhosis in Mexico: Similitudes and differences with other world regions显示文摘AIM To investigate the main current etiologies of cirrhosis in Mexico.METHODS We performed a cross-sectional retrospective multicenter study that included eight hospitals in different areas of Mexico. These hospitals provide health care to people of diverse social classes. The inclusion criteria were a histological, clinical, biochemical, endoscopic, or imaging diagnosis of liver cirrhosis. Data were obtained during a 5-year period(January 2012-December 2017). RESULTS A total of 1210 patients were included. The mean age was 62.5 years(SD = 12.1), and the percentages of men and women were similar(52.0% vs 48.0%). The most frequent causes of liver cirrhosis were hepatitis C virus(HCV)(36.2%), alcoholic liver disease(ALD)(31.2%), and nonalcoholic steatohepatitis(23.2%), and the least frequent were hepatitis B virus(1.1%), autoimmune disorders(7.3%), and other conditions(1.0%).CONCLUSION HCV and ALD are the most frequent causes of cirrhosis in Mexico. However, we note that non-alcoholic fatty liver disease(NAFLD) as an etiology of cirrhosis increased by 100% compared with the rate noted previously. We conclude that NAFLD will soon become one of the most frequent etiologies of liver cirrhosis in Mexico. | Nahum Méndez-Sánchez Felipe Zamarripa-Dorsey Arturo Panduro Emma Purón-González Edgar Ulises Coronado-Alejandro Carlos Alejandro Cortez-Hernández Fátima Higuera de la Tijera José Luis Pérez-Hernández Eira Cerda-Reyes Heriberto Rodríguez-Hernández Vania César Cruz-Ramón Oscar Lenin Ramírez-Pérez Nancy Edith Aguilar-Olivos Olga Fabiola Rodríguez-Martínez Samantha Cabrera-Palma Guillermo Cabrera-álvarez | 2018 | World Journal of Clinical Cases2018，6，15： | 2 |
| 5 | Computerized physician order entry‐based system to prevent HBV reactivation in patients treated with biologic agents: The PRESCRIB project显示文摘 | Blanca Sampedro Cándido Hernández‐López José Ramón Ferrandiz Aitziber Illaro Emilio Fábrega Antonio Cuadrado Paula Iruzubieta Susana Menéndez Joaquín Cabezas Javier Crespo | 2014 | Hepatology2014，，1： | 2 |
| 6 | Biological characterization of Drosophila Rapgap1,a GTP ase activating protein for Rap1显示文摘 | Chen F Barkett M Ram K T | 1997 | Proc Natl Acad Sci USA1997，94，12： | 1 |
| 7 | Epidermoid splenic cysts and partial splenectomy显示文摘 | Seguel Ramírez F Alonso Calderón JL Ollero Caprani JM | | 0，，02： | 1 |
| 8 | A Multicenter, Randomized, Clinical Trial of Hormonal Therapy in the Prevention of Rebleeding From Gastrointestinal Angiodysplasia显示文摘 | Félix Junquera Faust Feu Michel Papo Sebastián Videla José Ramón Armengol Josep Mar??a Bordas Esteban Saperas Josep M. Piqué Juan-Ramón Malagelada | 2001 | Gastroenterology2001，，5： | 1 |
| 9 | Antivirals for management of herpes zoster including ophthalmicus: a systematic review of high-quality randomized controlled trials 显示文摘 | McDonald E M de Kock J Ram F S | 2012 | Antivir Ther2012，17，2： | 1 |
| 10 | Role of bacterial virulence proteins in Agrobacterium-mediated transformation of As- pergillus awamori 显示文摘 | Michielse C B Ram A F Hooykaas P J | 2004 | Fungal Genet Biol2004，45，： | 1 |
| 11 | Electrical properties of carbon black filled polyethylene显示文摘 | M Narkis A Ram F Flashmer | 1978 | Polym Eng Sci1978，18，8： | 1 |
| 12 | A molecular and genomic view of the fungal cell wall显示文摘 | Klis F M Ram A F J De Groot P W J | 2007 | Biology of the Fungal Cell2007，8，： | 1 |
| 13 | The anti- fungal protein AFP from Aspergillus giganteus inhibits chitin synthesis in sensitive fungi 显示文摘 | Hagen S Florentine M Ram A F Meyer V | 2007 | Appl Environ Microbiol2007，73，7： | 1 |
| 14 | Low density lipoprotein cholesterol-lowering effects of AMG 145, a monoelonal antibody to proprotein convertase subtilisin/kexin type 9 serine protease in patients with heterozygous familial hypereholesterolemia clinical perspective the reduction of LDL-C with PCSK9 Inhibition in Heterozygous Familial Hypercholesterolemia Disorder ( RUTHERFORD ) randomized trial显示文摘 | RaM F Scott R Somaratne R | 2012 | Circulation2012，126，20： | 1 |
| 15 | Sustained Post - Mating Response in Drosophila melanogaster Requires Multiple Seminal Fluid Proteins 显示文摘 | Ram K R Wolfner M F | 2007 | PLoS Genet2007，3，12： | 1 |
| 16 | Modelization of the spatial distribution of corn head smut ($ponson~n teilinum Langdon and Fullerton) in Mexico显示文摘 | Sanchez-Pale J R Ram/rez-Davila J F Gonzalez-Huerta A | 2011 | Spanish Journal of Agricultural Reseach2011，9，3： | 1 |
| 17 | Comparing the effectiveness of in-tranasal fentanyl spray with oral transraucosal fentanyl citratein breakthrough pain显示文摘 | Shellard S E Ram F S | 2015 | Int J Palliat Nurs2015，21，10： | 1 |
| 18 | Quantitation of adipose conversion and triglycerides by staining intracytop lasmic lipids with oil red O显示文摘 | Ram (rez-Zacar í as J L Castro-Munozledo F Kuri-Hareueh W | 1992 | Histochemistry1992，97，6： | 1 |
| 19 | 17 beta-Estradiol attenuates voltage-dependent Ca^2+ currents in A7r5 vascular smooth muscle cell line显示文摘 | Zhang F Ram JL Standley PR | 1994 | Am J Physiol1994，266，41： | 1 |
| 20 | Pressure measurements in steel silo with eccentric hoppers显示文摘 | RAMíREZ A NIELSEN J AYUGA F | 2010 | Powder Technology2010，201，1： | 1 |
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