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| 1 | 冠状动脉内影像学临床应用专家共识(第一部分):对冠状动脉介入治疗的指导与优化显示文摘欧洲心血管介入协会(EAPCI)专家组系统总结了血管内超声(IVUS)和光学相干断层成像(OCT)这两种血管内影像学检查临床应用指征的现有证据,提供了关于IVUS和OCT指导经皮冠状动脉介入治疗(PCI)的应用价值,并明确了最可能从腔内影像学指导的介入治疗中获得临床收益的患者或病变类型,同时详细论述了PCI前如何使用IVUS或OCT优化支架尺寸(支架长度和直径)和手术策略的选择。此外,专家推荐对支架失败(支架内再狭窄或支架内血栓形成)的患者应常规进行冠状动脉内影像学检查,并首选OCT。最后,重点论述了IVUS和OCT在指导PCI和评估支架失败两个方面的优势和局限性,并对未来需要深入研究的领域进行了展望。 | Lorenz Raber Gary S Mintz Konstantinos C Koskinas Thomas W Johnson Niels R Holm Yoshinubo Onuma Maria D Radu Michael Joner Bo Yu Haibo Jia Nicolas Meneveau Jose M.de la Torre Hemandez Javier Escaned Jonathan Hill Francesco Prati Antonio Colombo Carlo di Mario Evelyn Regar Davide Capodanno William Wijns Robert A Byme Giulio Guagliumi | 2019 | 中华心血管病杂志2019，47，1： | 17 |
| 2 | Learning tasks as a possible treatment for DNA lesions induced by oxidative stress in hippocampal neurons显示文摘Reactive oxygen species have been implicated in conditions ranging from cardiovascular dysfunction,arthritis,cancer,to aging and age-related disorders.The organism developed several pathways to counteract these effects,with base excision repair being responsible for repairing one of the major base lesions(8-oxoG) in all organisms.Epidemiological evidence suggests that cognitive stimulation makes the brain more resilient to damage or degeneration.Recent studies have linked enriched environment to reduction of oxidative stressin neurons of mice with Alzheimer's disease-like disease,but given its complexity it is not clear what specific aspect of enriched environment has therapeutic effects.Studies from molecular biology have shown that the protein p300,which is a transcription co-activator required for consolidation of memories during specific learning tasks,is at the same time involved in DNA replication and repair,playing a central role in the long-patch pathway of base excision repair.Based on the evidence,we propose that learning tasks such as novel object recognition could be tested as possible methods of base excision repair facilitation,hence inducing DNA repair in the hippocampal neurons.If this method proves to be effective,it could be the start for designing similar tasks for humans,as a behavioral therapeutic complement to the classical drug-based therapy in treating neurodegenerative disorders.This review presents the current status of therapeutic methods used in treating neurodegenerative diseases induced by reactive oxygen species and proposes a new approach based on existing data. | Dragos Cīrneci Radu Silaghi-Dumitrescu | 2013 | Neural Regeneration Research2013，8，32： | 7 |
| 3 | Differential proton sensitivity of related G protein-coupled receptors T cell death-associated gene 8 and G2A expressed in immune cells显示文摘 | Radu C G Nijagal A McLaughlin J | 2005 | Proc Natl Acad Sci USA2005，102，5： | 1 |
| 4 | The effect of water treeing on the electric field distribution of XLPE显示文摘 | Radu I Acedo M Filippini J C | 2000 | IEEE Trans on Dielectrics and Electrical Insulation2000，7，6： | 1 |
| 5 | Delineation of gross tumor volume (GTV) for radiation treatment planning of locally advanced rectal cancer using information from MRI or FDG-PET/ CT: a prospective study 显示文摘 | Braendengen M Hansson K Radu C | 2011 | Int J Radiat Oneol Biol Phys2011，81，4： | 1 |
| 6 | Influence of water trees on the electric field distribution and breakdown in the pointpoint geometry显示文摘 | Radu I Notingher P V Filippini J C | 2000 | Journal of Electrostatics2000，48，： | 1 |
| 7 | The biological effect of the electrical field treatment on the potato seed:agro- nomic evaluation显示文摘 | Radu C Victor D Mona P | 2005 | Journal of Electrostatics2005，63，： | 1 |
| 8 | Alphaherpesvirus US3-mediated reorganization of the actin cytoskeleton is mediated by group A p21-activated kinases显示文摘 | Van den Broeke C Radu M Deruelle M | | 0，，： | 1 |
| 9 | Transient ferromagnetic-like state mediating ultrafast eversal of antiferromagnetically coupled spins显示文摘 | Radu I Vahaplar K Stamm C | 2011 | Nature2011，472，： | 1 |
| 10 | Role of group A p21-activated kinases in the anti-apoptotic activity of the pseudorabies virus US3 protein kinase显示文摘 | Broeke C Radu M Nauwynck H J | | 0，，01： | 1 |
| 11 | A polyamidoamine dendrimer-capped mesoporous silica nanosphere-based gene transfection reagent 显示文摘 | Radu D R Lai C Y Jeftinija K | 2004 | Journal of the American Chemical Society2004，126，13： | 1 |
| 12 | The biological effect ofthe electrical field treatment on the potatoseed:agronomic evaluation显示文摘 | Radu C Victor D Mona P | 2005 | Journal of Electrostatics2005，63，610： | 1 |
| 13 | The effect of water treeing on the electric field distribution of XLPE- consequences for the dielectric strength显示文摘 | Radu I Acedo M Filippini J C | 2000 | IEEE Transactions on Dielectrics and Electrical Insulation2000，7，6： | 1 |
| 14 | Two or more synchronous combination of noninvasive tests to increase accuracy of liver fibrosis assessement in chronic hepatitis C ; results from a cohort of 446 patients 显示文摘 | Crisan D Radu C Lupsor M | 2012 | Hepat Mon2012，12，3： | 1 |
| 15 | Histological and immunohistochemical aspects of papillary thyroid cancer显示文摘 | Radu T G Mogoant L Busuioc C J | 2014 | Rom J Morphol Embryol2014，56，2： | 1 |
| 16 | Hofitede's Model of National Cultural Differences and Their Consequences : A Triumph of Faith-A Failure of Analysis 显示文摘 | Baban C F Baban M Radu I E | 2002 | Human Relations2002，55，1： | 1 |
| 17 | Analytical and numerical stu dy on the maximum force developed by a V-beam thermal actuator显示文摘 | Radu S C Mircea C D Marius P | 2014 | Procedia Technology2014，12，： | 1 |
| 18 | An Analytic Solution for the Perspective d-Point Problem 显示文摘 | Radu H Bernard C Olivier L | 1989 | Computer Vision and Pattern Recognition1989，，： | 1 |
| 19 | An emerging role for p21-activated kinases(Paks)inviral infections显示文摘 | Van den Broeke C Radu M Chernoff J Favoreel H W | 2010 | Trends Cell Biol2010，20，： | 1 |
| 20 | Soil-Plant-Man Relationships in Heavy Metal Polluted Areas in Roma- nia显示文摘 | Radu L Corneliu R Stelian C | 1996 | Applied Geochemistry1996，11，： | 1 |
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