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| 1 | Real-life chromoendoscopy for dysplasia surveillance in ulcerative colitis显示文摘AIM To evaluate the use of chromoendoscopy for surveillance of ulcerative colitis in a real-life community hospital setting.METHODS Patients with extensive ulcerative colitis, having disease duration of more than 8 years and who presented between the years of 1999 to 2013, were offered enrolment in this single cohort prospective study. All participants underwent standard bowel preparation with sodium phosphate and chromoendoscopy. Two expert endoscopists, novice to chromoendoscopy, evaluated each segment of the colon with standarddefinition colonoscopes after spray application of 0.4% indigo carmine. All observed lesions were recorded and evaluated before being removed and/or biopsied. In addition, nontargeted biopsies were taken from each segment of the colon. The dysplasia detection rate and dysplasia detection yield were ascertained. RESULTS A total of 21 neoplastic lesions(2 carcinomas, 4 of high-grade dysplasia and 15 of low-grade dysplasia) and 27 nondysplastic lesions were detected in 16 of the total 67 patients(70% male; median disease duration: 17 years; median age at diagnosis: 25 years; 92% aminosalicylate-treated). The dysplasia detection rate was 10.5%(7/67 patients). The dysplasia detection yield was 20.8%(10/48) for targeted biopsies and 3.5%(11/318) for nontargeted biopsies. The sensitivity and specificity for the macroscopic evaluation of neoplasia using chromoendoscopy were 48% [95% confidence interval(CI): 26%-70%] and 96%(95%CI: 93%-98%), respectively. The positive predictive and negative predictive values were 42%(95%CI: 27%-59%) and 97%(95%CI: 95%-98%), respectively. A total of 19/21 dysplastic lesions were detected in mucosa with histologic inflammation.CONCLUSION Chromoendoscopy seems to be of value for dysplasia surveillance of ulcerative colitis in a community hospital setting. The yield of non-targeted biopsies is negligible. | Pasquale Klepp Anita Tollisen Arne Roseth Milada Cvancarova Smastuen Solveig N Andersen Morten Vatn Bjorn A Moum Stephan Brackmann | 2018 | World Journal of Gastroenterology2018，24，35： | 3 |
| 2 | Faecal calprotectin: a novel test for the diagnosis of colorectal cancer 显示文摘 | Roseth AG Kristinsson J Fagerhol MK | 1993 | Scand J Gastroenterol1993，28，12： | 1 |
| 3 | Persistence of the De-Icing Additive Benzotriazole at an Abandoned Airport显示文摘 | Gijs D. Breedveld Roger Roseth Magnus Sparrevik Thomas Hartnik Lars J. Hem | 2003 | Water Air and Soil Pollution: Focus2003，，3： | 1 |
| 4 | Proteomic analysis of articular cartilage vesicles from normal and osteoarthritic cartilage 显示文摘 | Rosethal AK Gohr CM Ninomiya J | 2011 | Arthritis Rheum2011，63，2： | 1 |
| 5 | Faecal calprotectin:a novel test for the diagnosis of colorectal cancer显示文摘 | Roseth AG Kristinsson J Fagerhol MK | | 0，，12： | 1 |
| 6 | Faecal ealproteetin: a novel test for the diagnosis of eolorectal cancer? 显示文摘 | Roseth AG Kristinsson J Fagerhol MK | 1993 | Seand J Gastroenterol1993，28，： | 1 |
| 7 | Assessment of disease activity in ulcerative colitis by faecal calprotectin,a novel granulocyte marker protein显示文摘 | Roseth A G Aadland E Jahnsen J | 1997 | Digestion1997，58，2： | 1 |
| 8 | Normalization of faecal calprotectin:a predictor of mucosal healing in patients with inflammatory bowel disease显示文摘 | Roseth A G Aadland E Grzyb K | 2004 | Scand J Gastrcenterol2004，，39： | 1 |
| 9 | Correlation between faecal excretion of indium- 111-labelled granulocytes and calprotectin, a granulocyte marker protein, in patients with inflammatory bowel disease显示文摘 | Roseth AG Schmidt PN Fagerhol MK | 1999 | Scand J Gastroenterol1999，34，： | 1 |
| 10 | Bilirubin inhibits transport of Neurotransmitters in Synaptic Vesicles显示文摘 | Roseth S Hansen TW Fonnum F | 1998 | Pediatr Res1998，44，： | 1 |
| 11 | The impact of constructive controversy on moral development显示文摘 | Tichy M Johnson D W Johnson R T Roseth C J | 2010 | Journal of Applied Social Psychology2010，40，4： | 1 |
| 12 | Autonomy,Belongingness,and Engagement in School as Contributors to Adolescent Psychological Well-Being显示文摘 | VAN Ryzin Mark J GRAVELY Amy A ROSETH Cary J | | 0，，01： | 1 |
| 13 | Correlation between faecal excretion of indium-111-labelled granulocytes and calprotectin, a grannlocyte marker protein, in patients with inflammatory bowel disease 显示文摘 | Roseth AG Schmidt PN Fagerhol MK | 1999 | Scand J Gastroenterol1999，34，： | 1 |
| 14 | Assesment of the neutrophil dominating protein calprotectin in fecesa methodologic study 显示文摘 | Roseth AG Fagerhtol MK Aadland E | 1992 | Scand J Gastroenterol1992，27，9： | 1 |
| 15 | Assessment of disease ac- tivity in ulcerative colitis by faecal calprotectin, a novel granalocyte marker protein 显示文摘 | Roseth AG Aadland E Jahnsen J | 1997 | Digestion1997，55，2： | 1 |
| 16 | The case for urban consolidation 显示文摘 | Roseth J | 1991 | Architecture Australia1991，，3： | 1 |
| 17 | Photochemical degradation of benzotriazole 显示文摘 | Hem L J Hartnik T Roseth R | 2003 | Journal of Environmental Science and Health Part a-Toxic/Hazardous Substances & Environmental Engineering2003，38，3： | 1 |
| 18 | Persistence of the de-icing additive benzotriazole at an abandoned airport 显示文摘 | Breedveld G D Roseth R Sparrevik M | 2003 | Water Air & Soil Pollution : Focus2003，3，3： | 1 |
| 19 | Assessment of disease activity in ulcerative colitis by faecal calprotectin,a novel granulocyte marker protein显示文摘 | Roseth A G Aadland E Jahnsen J | 1997 | Digestion1997，58，2： | 1 |
| 20 | Treatment of tunnel wash waters-experiments with organic sorbent materials.PartⅠ:Removal of polycyclic aromatic hydrocarbons and nonpolar oil显示文摘Tunnel wash waters characterize all waters that run off after washing procedures of tunnels are performed.These waters represent a wide spectrum of organic and inorganic pollutants,such as polycyclic aromatic hydrocarbons(PAHs)and toxic metals.Removal of such contaminants from water runoff was investigated using laboratory tests after washing procedure was performed on two road tunnels in eastern Norway(Hanekleiv and Bragernes).Due to diverse character of both,treatment media and treated wash waters, the... | PARUCH Adam M ROSETH Roger | 2008 | Journal of Environmental Sciences2008，20，8： | 1 |
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