|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Diagnosis and management challenges of in-stent restenosis in coronary arteries显示文摘Over the course of the 3 decades, percutaneous coronary intervention(PCI) with stent implantation transformed the practice of cardiology. PCI with stenting is currently the most widely performed procedure for the treatment of symptomatic coronary disease. In large trials, drugeluting stents(DES) have led to a significant reduction in in-stent restenosis(ISR) rates, one of the major limitations of bare-metal stents. Due to these favorable findings, DES was rapidly and widely adopted enabling more complex coronary interventions. Nevertheless, ISR remains a serious concern as late stent complications. ISR mainly results from aggressive neointimal proliferation and neoatherosclerosis. DES-ISR treatment continues to be challenging complications for interventional cardiologists. | M Chadi Alraies Fahed Darmoch Ramyashree Tummala Ron Waksman | 2017 | World Journal of Cardiology2017，9，8： | 50 |
| 2 | Intestinal alkaline phosphatase in the colonic mucosa of children with inflammatory bowel disease显示文摘AIM:To investigate intestinal alkaline phosphatase(iAP) in the intestinal mucosa of children with inflammatory bowel disease(IBD).METHODS:Colonic biopsy samples were taken from 15 newly diagnosed IBD patients and from 10 healthy controls.In IBD patients,specimens were obtainedboth from inflamed and non-inflamed areas.The iAP mRNA and protein expression was determined by reverse transcription-polymerase chain reaction and Western blotting analysis,respectively.Tissue localization of iAP and Toll-like receptor(TLR) 4 was investigated by immunofluorescent staining.RESULTS:The iAP protein level in the inflamed mucosa of children with Crohn's disease(CD) and ulcerative colitis(UC) was significantly decreased when compared with controls(both P < 0.05).Similarly,we found a significantly decreased level of iAP protein in the inflamed mucosa in CD compared with non-inflamed mucosa in CD(P < 0.05).In addition,the iAP protein level in inflamed colonic mucosa in patients with UC was decreased compared with non-inflamed mucosa in patients with CD(P < 0.05).iAP protein levels in the non-inflamed mucosa of patients with CD were similar to controls.iAP mRNA expression in inflamed colonic mucosa of children with CD and UC was not significantly different from that in non-inflamed colonic mucosa with CD.Expression of iAP mRNA in patients with noninflamed mucosa and in controls were similar.Co-localization of iAP with TLR4 showed intense staining with a dotted-like pattern.iAP was present in the inflamed and non-inflamed mucosa of patients with CD,UC,and in control biopsy specimens,irrespective of whether it was present in the terminal ileum or in the colon.However,the fluorescent signal of TLR4 was more pronounced in the colon compared with the terminal ileum in all groups studied.CONCLUSION:Lower than normal iAP protein levels in inflamed mucosa of IBD patients may indicate a role for iAP in inflammatory lesions in IBD.Based on our results,administration of exogenous iAP enzyme to patients with the active form of IBD may be a therapeutic option. | Kriszta Molnár dám Vannay Beáta Szebeni Nóra Fanni Bánki Erna Sziksz ron Cseh Hajnalka Gyrffy Péter László Lakatos Mária Papp András Arató Gábor Veres | 2012 | World Journal of Gastroenterology2012，18，25： | 5 |
| 3 | Characteristics of allergic colitis in breast-fed infants in the absence of cow's milk allergy显示文摘AIM: To investigate the characteristics of mucosal le-sions and their relation to laboratory data and long-term follow up in breast-fed infants with allergic colitis. METHODS: In this study 31 breast-fed infants were prospectively evaluated (mean age, 17.4 wk) whose rectal bleeding had not ceased after a maternal elimi-nation diet for cow's milk. Thirty-four age-matched and breast-fed infants (mean age, 16.9 wk) with no rectal bleeding were enrolled for laboratory testing as con-trols. Laboratory findings, colonoscopic and histological characteristics were prospectively evaluated in infants with rectal bleeding. Long-term follow-up with differ-ent nutritional regimes (L-amino-acid based formula or breastfeeding) was also included. RESULTS: Iron deficiency, peripheral eosinophilia andthrombocytosis were significantly higher in patients with allergic colitis in comparison to controls (8.4±3.2 μmol/L vs 13.7±4.7 μmol/L, P<0.001; 0.67±0.49 G/L vs 0.33±0.17 G/L, P<0.001; 474±123 G/L vs 376±89 G/L, P<0.001, respectively). At colonosco-py, lymphonodular hyperplasia or aphthous ulceration were present in 83% of patients. Twenty-two patients were given L-amino acid-based formula and 8 contin-ued the previous feeding. Time to cessation of rectal bleeding was shorter in the special formula feeding group (mean, 1.4 wk; range, 0.5-3 wk) when com-pared with the breast-feeding group (mean, 5.3 wk; range, 2-9 wk). Nevertheless, none of the patients ex-hibited rectal bleeding at the 3-mo visit irrespective of the type of feeding. Peripheral eosinophilia and cessa-tion of rectal bleeding after administration of elemental formula correlated with a higher density of mucosal eosinophils. CONCLUSION: Infant hematochezia, after cow's milk allergy exclusion, is generally a benign and probably self-limiting disorder despite marked mucosal abnor-mality. Formula feeding results in shorter time to cessa-tion of rectal bleeding; however, breast-feeding should not be discouraged in long-lasting hematochezia. | Kriszta Molnár Petra Pintér Hajnalka Gyrffy ron Cseh Katalin Eszter Müller András Arató Gábor Veres | 2013 | World Journal of Gastroenterology2013，19，24： | 3 |
| 4 | 显示文摘 | Goebel Dan M Watkins Ron M Jameson Kristina K | 2007 | Propul Power2007，23，3： | 1 |
| 5 | Drug interaction between St John's wort and nevirapine显示文摘 | de Maat Monique MR Hoetelmans Richard M W Mathot Ron A A | 2001 | AIDS2001，15，3： | 1 |
| 6 | Preparation and properties of porous metal hydride compacts显示文摘 | RON M GRUEN D MENDELSOHN M | 1980 | Journal of the Less Common Metals1980，74，2： | 1 |
| 7 | Perceived usefulness,ease of use and electronic supermarket use显示文摘 | Ron H Divett M J | 2003 | Interna- tional Journal of Human-Computer Studies2003，59，3： | 1 |
| 8 | Molecular tools in rhizosphere microbiology-from single-cell to whole-community analysis显示文摘 | Sorensen J Nicolaisen M H Ron E | 2009 | Plant Soil2009，321，12： | 1 |
| 9 | Preparation and properties of porous metal hydridecompacts 显示文摘 | Ron M Gruen D Mendelsohn M | 1980 | Journalof the Less-Common Metals1980，74，2： | 1 |
| 10 | Carbon membraneds from precursors containing low-carbon residual polymers显示文摘 | Linkov Vhdimir M Sanderson Ron D Jacobs Ed P | 1994 | Polymer International1994，35，3： | 1 |
| 11 | Could heat shock transcription factors function as hydrogen peroxide sensors in plants显示文摘 | Gad M Ron M | 2006 | Annals of Botany2006，98，： | 1 |
| 12 | Technology foresight for wiring up the national innovation system experiences in Britain, Australia, and New Zealand 显示文摘 | BEN R M RON J | 1999 | Technological Forecasting and Social Change1999，，60： | 1 |
| 13 | Molecular tools in rhizosphere microbiology - from single - cell to whole - conununity analysis显示文摘 | Sorensen J Nicolaisen M H Ron E | 2009 | Plant and Soil2009，321，12： | 1 |
| 14 | Z-tenotomy of the superior oblique tendon and horizontal rectus muscle surgery for A-pattern horizontal strabismus显示文摘 | Ron Y Snir M Axer-Seigel R | 2009 | J AAPOS2009，13，1： | 1 |
| 15 | A hydrogen heat pump as a bus air conditioner 显示文摘 | Ron M | 1984 | Journal of the Less- Common Metals1984，104，2： | 1 |
| 16 | Experimental studies on the role of backfill and pipeline characteristics in the application of acoustic leak location to under around pipelines显示文摘 | Clark M Amanda Rewerts Lance E Robbers Ron R | 1997 | Review of Progress in Quantitative Non-destructive Evaluation1997，16，4： | 1 |
| 17 | Prevention of acute renal failure in traumatic rhabdomyolysis 显示文摘 | Ron D Taitelman U Michaelson M | 1984 | Arch In- tern Med1984，144，： | 1 |
| 18 | Permeability and thermal conductivity of porous metallicmatrix hydride compacts 显示文摘 | Bershadsky E Josephy Y Ron M | 1989 | Journal of the Less-Common Metals1989，153，1： | 1 |
| 19 | Pathogen- induced programmed cell death in tobacco 显示文摘 | Ron M Lee S Eric L | 1997 | Joumal of Ceil Science1997，110，： | 1 |
| 20 | Molecular tools in rhizosphere microbiology-from single-cell to whole-community analysis 显示文摘 | Srensen J Nicolaisen M H Ron E | 2009 | Plant and Soil2009，321，12： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员