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| 1 | Attention deficit hyperactivity disorder and gastrointestinal morbidity in a large cohort of young adults显示文摘BACKGROUND Although the association of attention deficit hyperactivity disorder(ADHD)with psychiatric disorders is well known,its association with somatic diseases is unclear.Only few studies have investigated the gastrointestinal(GI)morbidity in adult patients with ADHD.AIM To measure gastrointestinal comorbidity and its burden on healthcare in young adults with ADHD.METHODS The cohort included subjects aged 17-35 years recruited to the Israel Defense Forces in 2007-2013,33380 with ADHD and 355652 without(controls).The groups were compared for functional and inflammatory conditions of the gastrointestinal tract and clinic and specialist visits for gastrointestinal symptoms/disease during service(to 2016).Findings were analyzed by generalized linear models adjusted for background variables.RESULTS Compared to controls,the ADHD group had more diagnoses of functional gastrointestinal disorders(referred to as FGID),namely,dyspepsia[odds ratio(OR):1.48,95%confidence interval(CI):1.40-1.57,P<0.001],chronic constipation(OR:1.64,95%CI:1.48-1.81,P<0.001),and irritable bowel syndrome(OR:1.67,95%CI:1.56-1.80,P<0.001)but not of organic disorders(inflammatory bowel disease,celiac disease).They had more frequent primary care visits for gastrointestinal symptoms[rate ratio(RR):1.25,95%CI:1.24-1.26,P<0.001]and referrals to gastrointestinal specialists(RR:1.96,95%CI:1.88-2.03,P<0.001)and more episodes of recurrent gastrointestinal symptoms(RR:1.29,95%CI:1.21-1.38,P<0.001).Methylphenidate use increased the risk of dyspepsia(OR:1.49,95%CI:1.28-1.73,P<0.001)and constipation(OR:1.42,95%CI:1.09-1.84,P=0.009).CONCLUSION ADHD in young adults is associated with an excess of FGID and increased use of related health services.Research is needed to determine if an integrative approach treating both conditions will benefit these patients and cut costs. | Sivan Kedem Shlomit Yust-Katz Dan Carter Zohar Levi Ron Kedem Adi Dickstein Salah Daher Lior H Katz | 2020 | World Journal of Gastroenterology2020，26，42： | 2 |
| 2 | Ion beam synthesis of diamond-like carbon thin films containing copper nanocrystals 显示文摘 | Gerhards I Ronning C Hofsass H | 2003 | Journal of Applied Physics2003，93，2： | 1 |
| 3 | Perceived usefulness,ease of use and electronic supermarket use显示文摘 | Ron H Divett M J | 2003 | Interna- tional Journal of Human-Computer Studies2003，59，3： | 1 |
| 4 | Molecular tools in rhizosphere microbiology-from single-cell to whole-community analysis显示文摘 | Sorensen J Nicolaisen M H Ron E | 2009 | Plant Soil2009，321，12： | 1 |
| 5 | Molecular tools in rhizosphere microbiology - from single - cell to whole - conununity analysis显示文摘 | Sorensen J Nicolaisen M H Ron E | 2009 | Plant and Soil2009，321，12： | 1 |
| 6 | Switching characteristics of a gas trigatron operated in single and double trigger mode显示文摘 | NANU K RON P H IYENGAR S T | 1990 | IEEE Transactions on Electrical Insulation1990，25，2： | 1 |
| 7 | From safety verification to safety testing 显示文摘 | Rusu V MARCHAND H TSCHAEN V JE'RON T JEANNET B | 2004 | Lecture Notes in Computer Science LNCS2004，2978，： | 1 |
| 8 | The efficacy of spinosad againstthe western flower thrips, Frankliniella occidentalis, and its impact on associated biological control agents on greenhouse cucumbers in southern Ontario显示文摘 | Terri J Cynthia S D Ron H | 2005 | Pest Management Science2005，61，： | 1 |
| 9 | Block Rotation by Strike-Slip Faulting z Structural and Paleomagnetic Evidence 显示文摘 | Ron H Freund R Garfunkel Z | 1984 | Journal of Geophysical Research1984，89，： | 1 |
| 10 | Molecular tools in rhizosphere microbiology-from single-cell to whole-community analysis 显示文摘 | Srensen J Nicolaisen M H Ron E | 2009 | Plant and Soil2009，321，12： | 1 |
| 11 | Caloric equivalent of live weight loss of dairy cattle显示文摘 | Th Bath D L Ronning M Meyer J H | 1965 | J Dairy Sci1965，48，： | 1 |
| 12 | The spectrum of herpes simplex encephalitis in children 显示文摘 | De Tiege X Rozenberg F H~ron Be | 2008 | Eur J Paediatr Neurol2008，12，： | 1 |
| 13 | pGSTag-a versatile bacterial expression plasmid for enzymatic labeling of recombinant proteins显示文摘 | Ron D Dressler H | 1992 | Biotechniques1992，13，6： | 1 |
| 14 | Two-sensor ultrasonic spacecraft leak detection using structure-borne noise显示文摘 | STEPHEN D H RON R CHIMENTI D E | 2005 | Acoustical Society of America2005，6，2： | 1 |
| 15 | Microwave reduction of a nickeliferous laterite ore 显示文摘 | MICHAIL S MARIA T RON H | 2012 | Minerals Engineering2012，34，： | 1 |
| 16 | Post-translational processing of the interalpha-trypsin inhibitor in the human hepatoma HepG2 cell line显示文摘 | Héron A Bourguignon J Callé A | 1994 | Biochem J1994，302，2： | 1 |
| 17 | Education and Capital Development: Capital as Durable Personal, Social, Economic and Political Influences on the Happiness of Individuals显示文摘 | Ron H Dina S H Louis S | 2003 | Education2003，123，3： | 1 |
| 18 | Studies on the properties of p1 site-specific recombination;Evidence for topologically unlinked products following recombination显示文摘 | KEN A RON H NAT S | 1983 | Cell1983，32，： | 1 |
| 19 | Epitaxial BiFeO3 multiferroic thin film heterostructure 显示文摘 | WANG J NEA'rON J B ZHENG H | 2003 | Sci- ence2003，299，： | 1 |
| 20 | Punicic acid, a conjugated linolenic acid, inhibits TNF α-induced neutrophil hyperactivation and protects from experimental colon inflammation in rats显示文摘 | Boussetta T Raad H Lette'ron P | 2009 | PLoS One2009，4，7： | 1 |
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