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| 1 | Predicting lower limb periprosthetic joint infections: A review of risk factors and their classification显示文摘AIM To undertook a systematic review to determine factors that increase a patient's risk of developing lower limb periprosthetic joint infections(PJI).METHODS This systematic review included full-text studies that reviewed risk factors of developing either a hip or knee PJI following a primary arthroplasty published from January 1998 to November 2016. A variety of keywords were used to identify studies through international databases referencing hip arthroplasty, knee arthroplasty, infection, and risk factors. Studies were only included if they included greater than 20 patients in their study cohort, and there was clear documentation of the statistical parameter used; specifically P-value, hazard ratio, relative risk, or/and odds ratio(OR). Furthermore a quality assessment criteria for the individual studies was undertaken to evaluate the presence of record and reporting bias. RESULTS Twenty-seven original studies reviewing risk factors relating to primary total hip and knee arthroplasty infections were included. Four studies(14.8%) reviewed PJI of the hip, 3(11.21%) of the knee, and 20(74.1%) reviewed both joints. Nineteen studies(70.4%) were retrospective and 8(29.6%) prospective. Record bias was identified in the majority of studies(66.7%). The definition of PJI varied amongst the studies but there was a general consensus to define infection by previously validated methods. The most significant risks were the use of preoperative high dose steroids(OR = 21.0, 95%CI: 3.5-127.2, P < 0.001), a BMI above 50(OR = 18.3, P < 0.001), tobacco use(OR = 12.76, 95%CI: 2.47-66.16, P= 0.017), body mass index below 20(OR = 6.00, 95%CI: 1.2-30.9, P = 0.033), diabetes(OR = 5.47, 95%CI: 1.77-16.97, P = 0.003), and coronary artery disease(OR = 5.10, 95%CI: 1.3-19.8, P = 0.017).CONCLUSION We have highlighted the need for the provider to optimise modifiable risk factors, and develop strategies to limit the impact of non-modifiable factors. | David A George Lorenzo Drago Sara Scarponi Enrico Gallazzi Fares S Haddad Carlo L Romano | 2017 | World Journal of Orthopedics2017，8，5： | 3 |
| 2 | Gemcitabine plus oxaliplatin (GEMOX) combined with cetuximab in patients with progressive advanced stage hepatocellular carcinoma:results of a multicenter phase 2 study显示文摘 | Asnacios A Fartoux L Romano O | | 0，，12： | 2 |
| 3 | Inhibition of monocyte chemotactic proteins21 synthesis by statins显示文摘 | Romano M Diomede L Sironi M | 2000 | Lab Invest2000，80，7： | 1 |
| 4 | Spiral computed tomography in the assessment of vascular lesions of the pelvis due to blunt trauma显示文摘 | Pinto A De Lutio Di Castelguidone E | 2000 | Radiol Med ( Torino)2000，100，12： | 1 |
| 5 | Outcome on acute myeloid leukemia patients with hyperleukocytosis in Brazil显示文摘 | Oliveira L C Romano L G Prado-Junior B P | 2010 | Med Oncol2010，27，4： | 1 |
| 6 | Where Is Cost Management Going? 显示文摘 | | 1990 | Management Accounting1990，，8： | 1 |
| 7 | Postconditioning is an effective strategy to reduce renal ischemia /reperfusion injury 显示文摘 | Serviddio G Romano AD Gesualdo L | 2008 | Nephrol Dial Transplant2008，23，5： | 1 |
| 8 | Monitoring activities from multiple video streams: Establishing a common coordinate frame显示文摘 | ROMANO R LEE L STEIN G | 2000 | IEEE Transactions on Pattern Analysis and Machine Intelligence( PAMI)2000，22，8： | 1 |
| 9 | Uncoupling auxin and ethylene effects in transgenic tobacco and Arabidposis plants显示文摘 | Romano C P Cooper M L Klee H J | | 0，，02： | 1 |
| 10 | mi R-34c may protect lung cancer cells from paclitaxel-induced apoptosis显示文摘 | Catuogno S Cerchia L Romano G | 2013 | Oncogene2013，32，3： | 1 |
| 11 | Gemcitabine plus oxali- platin (GEMOX) combined with cetuximab in patients with pro- gressive advanced stage hepatocellular carcinoma : results of a mul- ticenter phase 2study显示文摘 | Asnaeios A Fartoux L Romano O | 2008 | Cancer2008，112，12： | 1 |
| 12 | An antiglobulin reagent labelled with colloidal gold for use in electron mieroscopy显示文摘 | Romano E L Stolinski C Hughes-Jones N C | 1974 | Immunochemistry1974，11，8： | 1 |
| 13 | Gemcitabine plus oxaliplatin (GEMOX) combined with cetuximab in patients with progressive advanced stage hepatocellular carcinoma: resuits of a multicenter phase 2 study 显示文摘 | Asnacios A Fartoux L Romano O | 2008 | Cancer2008，112，12： | 1 |
| 14 | Hepatitis E in Italy: a long-term prospective study显示文摘 | Romano L Paladini S Tagliacarne C | 2011 | J Hepatol2011，54，1： | 1 |
| 15 | Gemcitabine plus oxaliplatin (GEMOX) combined with cetuximab in patients with progressive advanced stage hepatocellular carcinoma:results of a multicenter phase 2 study显示文摘 | Asnacios A Fartoux L Romano O | 2008 | Cancer2008，112，： | 1 |
| 16 | Olive flowering as an indicator of local climatic changes显示文摘 | ORLANDI F RUGA L ROMANO B | 2005 | Theoretical and Applied climatology2005，81，34： | 1 |
| 17 | Phase noise in digital frequency dividers 显示文摘 | LEVANTINO S ROMANO L PELLERANO S | 2004 | IEEE Journal of Solid-State Circuits2004，39，5： | 1 |
| 18 | Biogenic amine in wines显示文摘 | Beneduce L Romano A Capozzi V | 2010 | Annals of Microbiology2010，60，4： | 1 |
| 19 | Phase Noise in Digital Frequency Dividers显示文摘 | Levantino S Romano L Pellerano S | 2004 | IEEE J of Solid-State Circuits2004，39，5： | 1 |
| 20 | A Pedagogical Treatment of Bilateral Monopoly 显示文摘 | Roger D Blair David L Kaserman Richard E Romano | 1989 | Southern Economic Journal1989，55，4： | 1 |
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