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| 1 | Management of recurrent rectal cancer:A population based study in greater Amsterdam显示文摘AIM: To analyze,retrospectively in a population-based study,the management and survival of patients with recurrent rectal cancer initially treated with a macroscopically radical resection obtained with total mesorectal excision (TME). METHODS: All rectal carcinomas diagnosed during 1998 to 2000 and initially treated with a macroscopically radical resection (632 patients) were selected from the Amsterdam Cancer Registry. For patients with recurrent disease,information on treatment of the recurrence was collected from the medical records. RESULTS: Local recurrence with or without clinically apparent distant dissemination occurred in 62 patients (10%). Thirty-two patients had an isolated local recurrence. Ten of these 32 patients (31%) underwent radical re-resection and experienced the highest survival (three quarters survived for at least 3 years). Eight patients (25%) underwent non-radical surgery (median survival 24 mo),seven patients (22%) were treated with radio-and/or chemotherapy without surgery (median survival 15 mo) and seven patients (22%) only received best supportive care (median survival 5 mo). Distant dissemination occurred in 124 patients (20%) of whom 30 patients also had a local recurrence. The majority (54%) of these patients were treated with radio-and/or chemotherapy without surgery (median survival 15 mo). Twenty-seven percent of these patients only received best supportive care (median survival 6 mo),while 16% underwent surgery for their recurrence. Survival was best in the latter group (median survival 32 mo). CONCLUSION: Although treatment options and survival are limited in case of recurrent rectal cancer after radical local resection obtained with TME,patients can benefit from additional treatment,especially if a radical resection is feasible. | Roel Bakx Otto Visser Judith Josso Sybren Meijer J Frederik M Slors J Jan B van Lanschot | 2008 | World Journal of Gastroenterology2008，14，39： | 17 |
| 2 | Percutaneous closure of secundum type atrial septal defects:More than 5-year follow-up显示文摘AIM: To investigate long-term efficacy of two different devices more than five years after percutaneous atrial septal defect(ASD) closure in adults.METHODS: All patients who underwent percutaneous closure of an ASD in the St. Antonius Hospital, Nieuwegein, The Netherlands, between February 1998 and December 2006 were included. Percutaneous closure took place under general anaesthesia and transesophageal echocardiographic moni toring. Transthoracic echocardiography(TTE) was performed 24 h post-procedure to visualize the device position and to look for residual shunting using color Doppler. All complications were registered. All patients were invited for an outpatient visit and contrast TTE more than 5-years after closure. Efficacy was based on the presence of a residual right-to-left shunt(RLS), graded as minimal, moderate or severe. The presence of a residual left-to-right shunt(LRS) was diagnosed using color Doppler, and was not graded. Descriptive statistics were used for patients' characteristics. Univariate analysis was used to identify predictors for residual shunting.RESULTS: In total, 104 patients(mean age 45.5 ± 17.1 years) underwent percutaneous ASD closure using an Amplatzer device(ASO) in 76 patients and a Cardioseal/Starflex device(CS/SF) in 28 patients. The mean follow-up was 6.4 ± 3.4 years. Device migration occurred in 4 patients of whom two cases occurred during the index hospitalization(1 ASO, 1 CS/SF). The other 2 cases of device migration occurred during the first 6 mo of follow-up(2 CS/SF). The recurrent thrombo-embolic event rate was similar in both groups: 0.4% per follow-up year. More than 12 mo post-ASD closure and latest follow-up, new-onset supraventricular tachyarrhythmia's occurred in 3.9% and 0% for the ASO and CS/SF group, respectively. The RLS rate at latest follow-up was 17.4%(minimal 10.9%, moderate 2.2%, severe 4.3%) and 45.5%(minimal 27.3%, moderate 18.2%, severe 0%) for the ASO- and CS/SF groups, respectively. There was no residual LRS in both groups.CONCLUSION: Percutaneous ASD closure has good long-term safety and efficacy profiles. The residual RLS rate seems to be high more than 5 years after closure, especially in the CS/SF. Residual LRS was not observed. | Roel JR Snijder Maarten J Suttorp Jurrien M Ten Berg Martijn C Post | 2015 | World Journal of Cardiology2015，7，3： | 6 |
| 3 | Removal of PCBs from wastewater using fly ash显示文摘 | NOLLET H ROELS M LUTGEN P | 2003 | Chemosphere2003，53，6： | 1 |
| 4 | The choice of stock ownership structure :agency costs, monitoring, and the decision to go public显示文摘 | Pagano M A Roel | 1998 | Quarterly Journal of Economics1998，，113： | 1 |
| 5 | Heterogeneity in the structure of watersoluble arabianxylans in European wheat fours of variable bread-making quality显示文摘 | CLEEMPUT G ROELS S P VANOORT M | 1993 | Cereal Chem1993，70，3： | 1 |
| 6 | The use of FDG- PET/CT and diffusion-weighted magnetic resonance imaging for response prediction before, during and after preoperative chemoradiotherapy for rectal cancer显示文摘 | Lambrecht M Deroose C Roels S | 2010 | Acta Oneol2010，49，7： | 1 |
| 7 | The choice of stock ownership structure : A- gency costs, monitoring, and the decision to go public 显示文摘 | M PAGANO A ROEL | 1998 | Quar- terly Journal of Economics1998，113，1： | 1 |
| 8 | Heterogeneity in the structure of water-soluble arabinoxylans in European wheat flours of variable bread-making quality显示文摘 | Cleemput G Roels S P Oort M V | 1993 | Cereal Chemistry1993，70，3： | 1 |
| 9 | Determinants of annual fluxes of CO2 and N2O in long-term no-tillage and conventional tillage systems in northern Franee显示文摘 | KATRIEN O ROEL M ERIC G | 2007 | Soil & Tillage Research2007，95，： | 1 |
| 10 | Optimization of plantain (Musa AAB) micro-propagation by temporary im- mersion system 显示文摘 | ROELS S ESCALONA M CEJAS I | 2005 | Plant Cell Tissue Organ Culture2005，82，： | 1 |
| 11 | The Effects of Task Constraints on Visual Search Behavior and Decision-Making Skill in Youth Soccer Players 显示文摘 | ROEL VAEYENS MATFIEU LENOIR Williams A M | 2007 | Journal of Sport & Exercise Psychology2007，，29： | 1 |
| 12 | Heterogeneity in the structure of water soluble arabianxylans in European wheat fours of variable bread making quality显示文摘 | Cleemput G Roels S P Vanoort M | 1993 | Cereal Chem1993，70，3： | 1 |
| 13 | Optimization of plantain (Musa AAB) micro-propagation by temporary immersion system显示文摘 | ROELS S ESCALONA M CEJAS I | 2005 | Plant Cell Tissue Organ Culture2005，，82： | 1 |
| 14 | The Assumed Assimilation of Cholesterol by Lactobacilli and Bifidobacterium bifidum is due to Their Bile Salt - deconjugation Activity显示文摘 | KLAVER F A M ROEL V D M | 1993 | Applied and Enviromental Microbiology1993，59，： | 1 |
| 15 | Cadmium a possible etio- logical factor in peripheral polyneuropathy 显示文摘 | Viaene M K Roels H A Leendcrs J | 1999 | Neurotoxicology1999，20，1： | 1 |
| 16 | The Choice of Stock Ownership Structure: Agency Costs, Monitoring, and the Decision to go Public 显示文摘 | PAGANO M ROEL A | 1998 | Quarterly Journal of Economics1998，112，： | 1 |
| 17 | Phase I and pharmacokinetic study of a daily times 5 short intravenous infusion schedule of 9-amino-camptothecin in a colloidaldispersion formulation in patients with advanced solid tumors显示文摘 | Virginine M M Herben Roel van Gijin Jan H M | 1999 | Journal of Clinical Oncology1999，17，： | 1 |
| 18 | Bioactivation of zearlenone by porcine hepatic biotransformafion 显示文摘 | Hassan M Roel F M Johanna F G | 2005 | Vet Res2005，36，： | 1 |
| 19 | Optimization of plantain (Musa AAB) micropropagation by temporary immersion system 显示文摘 | Roels S Escalona M Cejas I | 2005 | Plant Cell Tiss Org Cult2005，82，： | 1 |
| 20 | Fractional condensation of biomass pyrolysis vapors显示文摘 | Roel J M Wim F D Garcia-Perez M | 2011 | Energy and Fuels2011，25，4： | 1 |
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