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| 1 | 通过手术导致的重量损失由胃绕过在疾病的肥胖的病人改进非含酒精的脂肪肝疾病显示文摘 AIM:To evaluate the effects of surgical weight loss(Roux-en-Y gastric bypass with a modified Fobi-Capella technique) on non alcoholic fatty liver disease in obese patients.METHODS:A group of 26 morbidly obese patients aged 45 ± 2 years and with a body mass index > 40 kg/m 2 who underwent open surgical weight loss operations had paired liver biopsies,the first at surgery and the second after 16 ± 3 mo of weight loss.Biopsies were evaluated and compared in a blinded fashion.The presence of metabolic syndrome,anthropometric and biochemical variables were also assessed at baseline and at the time of the second biopsy.RESULTS:Percentage of excess weight loss was 72.1% ± 6.6%.There was a reduction in prevalence of metabolic syndrome from 57.7%(15 patients) to 7.7%(2 patients)(P < 0.001).Any significance difference was observed in aspartate aminotransferase or alanine aminotransferase between pre and postsurgery.There were improvements in steatosis(P < 0.001),lobular(P < 0.001) and portal(P < 0.05) inflammation and fibrosis(P < 0.001) at the second biopsy.There were 25(96.1%) patients with non alcoholic steatohepatitis(NASH) in their index biopsy and only four(15.3%) of the repeat biopsies fulfilled the criteria for NASH.The persistence of fibrosis(F > 1) was present in five patients at second biopsy.Steatosis and fibrosis at surgery were predictors of significant fibrosis postsurgery.CONCLUSION:Restrictive mildly malabsorptive surgery provides significant weight loss,resolution of metabolic syndrome and associated abnormal liver histological features in most obese patients. | Víctor Vargas Helena Allende Albert Lecube Maria Teresa Salcedo Juan A Baena-Fustegueras José M Fort Joaquín Rivero Roser Ferrer Roberto Catalán Eva Pardina Santiago Ramón y Cajal Jaime Guardia Julia Peinado-Onsurbe | 2012 | World Journal of Hepatology2012,4,12: | 6 |
| 2 | Beta-blocker therapy in elderly patients with renal dysfunction and heart failure显示文摘OBJECTIVE To assess the role of beta-blockers(BB)in patients with chronic kidney disease(CKD)aged≥75 years.METHODS AND RESULTS From January 2008 to July 2014,we included 390 consecutive patients≥75 years of age with ejection fraction≤35%and glomerular filtration rate(GFR)≤60 m L/min per 1.73 m^2.We analyzed the relationship between treatment with BB and mortality or cardiovascular events.The mean age of our population was 82.6±4.1 years.Mean ejection fraction was 27.9%±6.5%.GFR was 60-45 m L/min per 1.73 m^2 in 50.3%of patients,45-30 m L/min per 1.73 m^2 in 37.4%,and<30 m L/min per 1.73 m^2 in 12.3%.At the conclusion of follow-up,67.4%of patients were receiving BB.The median follow-up was28.04(IR:19.41-36.67)months.During the study period,211 patients(54.1%)died and 257(65.9%)had a major cardiovascular event(death or hospitalization for heart failure).BB use was significantly associated with a reduced risk of death(HR=0.51,95%CI:0.35-0.74;P<0.001).Patients receiving BB consistently showed a reduced risk of death across the different stages of CKD:stage IIIa(GFR=30-45 m L/min per 1.73 m^2;HR=0.47,95%CI:0.26-0.86,P<0.0001),stage IIIb(GFR 30-45 m L/min per 1.73 m^2;HR=0.55,95%CI:0.26-1.06,P=0.007),and stages IV and V(GFR<30 m L/min per 1.73 m~2;HR=0.29,95%CI:0.11-0.76;P=0.047).CONCLUSIONS The use of BB in elderly patients with HFr EF and renal impairment was associated with a better prognosis.Use of BB should be encouraged when possible. | Juan Martínez-Milla Marcelino Cortés García Julia Anna Palfy Mikel Taibo Urquía Marta López Castillo Ana Devesa Arbiol Ana Lucía Rivero Monteagudo María Luisa Martín Mariscal Inés Jiménez-Varas Sem Briongos Figuero Juan Antonio Franco-Pelaéz JoséTuñón | 2021 | Journal of Geriatric Cardiology2021,18,1: | 3 |
| 3 | In vivo optical quality of posterior-chamber phakic implantable collamer lenses with a central port显示文摘Background:The aim of this review is to summarize the optical quality results in patients following the implantation of the V4c implantable collamer lens with a central port(ICL,STAAR Surgical Inc.).Main text:A literature search in several databases was carried out to identify those publications,both prospective,retrospective and/or comparative with other refractive surgery procedures,reporting optical outcomes of patients who were implanted with the V4c ICL model.A total of 17 clinical studies published between 2012 and 2021 were included in this review.A detailed analysis of the available data was performed including number of eyes,follow-up and preoperative spherical equivalent.Specifically,the review focused on several optical parameters including higher-order aberrations(HOAs),modulation transfer function(MTF)cut-off frequency and Strehl ratio.This review encompassed a total of 817 eyes measured using different optical devices based on Hartmann-Shack,retinal image quality measurement and ray-tracing technologies at different follow-ups.Conclusions:The outcomes found in this review lead us to conclude that the ICL V4c model provides good optical quality,by means of different metrics,when implanted. | Robert Montés-Micó Francisco Pastor-Pascual Enrique Artiaga-Elordi Ramón Ruiz-Mesa Pedro Tañá-Rivero | 2021 | Eye and Vision2021,8,1: | 3 |
| 4 | Tool wear detection in dry high-speed milling based upon the analysis of machine internal signals 显示文摘 | RIVERO A DE LACALLE L N L PENALVA M L | 2008 | Mechatronics2008,18,10: | 1 |
| 5 | Differential gene expres- sion in skeletal muscle cells after membrane depolarization显示文摘 | Juretlc N Urzua U Riveros N | 2007 | J Cell Physiol2007,5,: | 1 |
| 6 | Liver stiff- ness predicts clinical outcome in human immunodeficiency virus/hepatitis C virus -coinfected patients with compensa- ted liver cirrhosis显示文摘 | Merchante N Rivero -Juarez A Tellez F | 2012 | Hepatology2012,56,1: | 1 |
| 7 | Differential gene expression in skeletal muscle cells after membrane depolarization显示文摘 | JURETIC N URZUA U RIVEROS N | 2007 | J Cell Physiol2007,210,3: | 1 |
| 8 | Acute pulmonary and hematological effects of two types of particle surrogates are influenced by their elemental composition显示文摘 | Medeiros Jr N Rivero DHRF Kasahara DI | 2004 | Environ Res2004,95,: | 1 |
| 9 | Prenatal Exposure to Methyldopa Leading to Hypertensive Crisis and Cardiac Failure in a Neonate 显示文摘 | Su JA Tang W Rivero N | 2014 | Pediatrics2014,28,4: | 1 |
| 10 | Risk factors for pulmonary Aspergillus terreus infection in patients with positive culture for filamentous fungi显示文摘 | Castón JJ Linares MJ Gallego C Rivero A Font P Solís F | | 0,,: | 1 |
| 11 | Isoflurane/nitrous oxide anesthesia induces increases in NMDA receptor subunit NR2B protein expression in the aged rat brain显示文摘 | Lana J. Mawhinney Juan Pablo de Rivero Vaccari Ofelia F. Alonso Christopher A. Jimenez Concepción Furones W. Javier Moreno Michael C. Lewis W. Dalton Dietrich Helen M. Bramlett | 2011 | Brain Research2011,,: | 1 |
| 12 | Basal ganglia calcification induced by excitotoxicity: an experimental model characterised by electron microscopy and X-ray microanalysis显示文摘 | N. Mahy Alberto Prats Alberto Riveros Noemí Andrés Fabián Bernal | 1999 | Acta Neuropathologica1999,,3: | 1 |
| 13 | Stacking of antimicrobiat genes in potato transgenic plants confers increased resistance to bacterial and fungal pathogens显示文摘 | Rivero M Furman N Mencacci N | 2012 | Journal of Biotechnology2012,157,2: | 1 |
| 14 | Efrect of growth conditions on production of violacein by Chromobacterium violaceum (BB-78 strain)显示文摘 | Riveros R Haun M Duran N | 1989 | Braz J Med Biol Res1989,22,5: | 1 |
| 15 | Systemic inflamma-tion in patients with chronic obstructive pulmonary disease who arecolonized with Pneumocystis jiroveci显示文摘 | Calderon EJ Rivero L Respaldiza N | 2007 | Clin Infect Dis2007,45,2: | 1 |
| 16 | Notch1 upregulates LPS-in-duced macrophage activation by increasing NF-kappaB activity显示文摘 | Monsalve E Ruiz-García A Baladrón V Ruiz-Hidalgo M J Sánchez-Solana B Rivero S | 2009 | Eur J Immunol2009,39,: | 1 |
| 17 | The physiology of host feeding in parasitic wasps: implications for survival 显示文摘 | Giron D Rivero A Mandon N | 2002 | Functional Ecology2002,16,: | 1 |
| 18 | Plasma Leptin and TNF-α Levels in Chronic Hepatitis C Patients and Their Relationship to Hepatic Fibrosis显示文摘 | Javier Crespo Montserrat Rivero Emilio Fábrega Amalía Cayón José Antonio Amado Maria Teresa García-Unzeta Fernando Pons-Romero | 2002 | Digestive Diseases and Sciences2002,,7: | 1 |
| 19 | The Technology - Activities of Daily Living Questionnaire: A Version with a Technology-Related Subscale显示文摘 | Mu?oz-neira Carlos López Oscar L Riveros Rodrigo Nú?ez-huasaf Javier Flores Patricia Slachevsky Andrea | 2012 | Dementia and Geriatric Cognitive Disorders2012,,6: | 1 |
| 20 | Immunohistochemical expression of HIF-1 alpha in response to early myocardial ischemia显示文摘 | Blanco Pampín J García Rivero SA Otero Cepeda XL | | 0,,01: | 1 |