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| 1 | Management of bacterial and fungal infections in end stage liver disease and liver transplantation: Current options and future directions显示文摘Patients with liver cirrhosis are susceptible to infections due to various mechanisms, including abnormalities of humoral and cell-mediated immunity and occurrence of bacterial translocation from the intestine. Bacterial infections are common and represent a reason for progression to liver failure and increased mortality. Fungal infections, mainly caused by Candida spp., are often associated to delayed diagnosis and high mortality rates. High level of suspicion along with prompt diagnosis and treatment of infections are warranted. Bacterial and fungal infections negatively affect the outcomes of liver transplant candidates and recipients, causing disease progression among patients on the waiting list and increasing mortality, especially in the early posttransplant period. Abdominal, biliary tract, and bloodstream infections caused by Gram-negative bacteria [e.g., Enterobacteriaceae and Pseudomonas aeruginosa(P. aeruginosa)] and Staphylococcus spp. are commonly encountered in liver transplant recipients. Due to frequent exposure to broad-spectrum antibiotics, invasive procedures, and prolonged hospitalizations, these patients are especially at risk of developing infections caused by multidrug resistant bacteria. The increase in antimicrobial resistance hampers the choice of an adequate empiric therapy and warrants the knowledge of the local microbial epidemiology and the implementation of infection control measures. The main characteristics and the management of bacterial and fungal infections in patients with liver cirrhosis and liver transplant recipients are presented. | Elda Righi | 2018 | World Journal of Gastroenterology2018，24，38： | 22 |
| 2 | 36例小细胞骨肉瘤的临床病理学、免疫组化及分子分析显示文摘Righi A,Gambarotti M,Longo S,et al. Sma11 ce11 osteosarco-ma:c1inicopatho1ogic,immunohistochemica1,and mo1ecu1ar a-na1ysis of 36 cases. Am J Surg Patho1,2015,39(5):691-9.小细胞骨肉瘤是骨肉瘤的一种非常罕见亚型,组织学类似骨的其它小细胞恶性肿瘤,特别是尤因肉瘤。为鉴别小细胞骨肉瘤及骨的其他原发性小细胞恶性肿瘤,作者对36例原发性骨的小细胞骨肉瘤进行CD99和SATB2(一种成骨细胞分化标志物)的免疫组化(IHC)表达情况评估。并通过荧光原位杂交和(或)逆转录聚合酶链反应( RT-PCR)分析了EWSR1和FUS 基因突变情况,进一步评估小细胞骨肉瘤和尤因肉瘤是否有相同的遗传性学改变。 | Righi A Gambarotti M Longo S 魏建国 许春伟 邰艳红 | 2015 | 临床与实验病理学杂志2015，31，6： | 5 |
| 3 | Impact of new treatment options for hepatitis c virus infection in liver transplantation显示文摘Liver transplant candidates and recipients with hepatitis C virus(HCV)-related liver disease greatly benefit from an effective antiviral therapy. The achievement of a sustained virological response before transplantation can prevent the recurrence of post-transplant HCV disease that occurs universally and correlates with enhanced progression to graft cirrhosis. Previous standard-of-care regimens(e.g.,pegylated-interferon plus ribavirin with or without first generation protease inhibitors,boceprevir and telaprevir) displayed suboptimal results and poor tolerance in liver transplant recipients. A new class of potent direct-acting antiviral agents(DAA) characterized by all-oral regimens with minimal side effects has been approved and included in the recent guidelines for the treatment of liver transplant recipients with recurrent HCV disease. Association of sofosbuvir with ribavirin and/or ledipasvir is recommended in liver transplant recipients and patients with decompensated cirrhosis. Other regimens include simeprevir,daclatasvir,and combination of other DAA. Possible interactions should be monitored,especially in coinfected human immunodeficiency virus/HCV patients receiving antiretrovirals. | Elda Righi Angela Londero Alessia Carnelutti Umberto Baccarani Matteo Bassetti | 2015 | World Journal of Gastroenterology2015，21，38： | 3 |
| 4 | ARFI elastography in patients with chronic autoimmune liver diseases: A preliminary study显示文摘 | S. Righi E. Fiorini C. De Molo V. Cipriano F. Cassani L. Muratori M. Lenzi A.M. Morselli Labate C. Serra | 2012 | Journal of Ultrasound2012，，4： | 2 |
| 5 | Extension of analytical indicial aerodynamics to generic trapezoidal wings in subsonic flow显示文摘Analytical indicial aerodynamic functions are calculated for several trapezoidal wings in subsonic flow, with a Mach number 0.3 Ma 0.7. The formulation herein proposed extends wellknown aerodynamic theories, which are limited to thin aerofoils in incompressible flow, to generic trapezoidal wing planforms. Firstly, a thorough study is executed to assess the accuracy and limitation of analytical predictions, using unsteady results from two state-of-the-art computational fluid dynamics solvers as cross-validated benchmarks. Indicial functions are calculated for a step change in the angle of attack and for a sharp-edge gust, each for four wing configurations and three Mach numbers. Then, analytical and computational indicial responses are used to predict dynamic derivatives and the maximum lift coefficient following an encounter with a one-minus-cosine gust. It is found that the analytical results are in excellent agreement with the computational results for all test cases. In particular, the deviation of the analytical results from the computational results is within the scatter or uncertainty in the data arising from using two computational fluid dynamics solvers. This indicates the usefulness of the developed analytical theories. | Andrea DA RONCH Antonino VENTURA Marcello RIGHI Matteo FRANCIOLINI Marco BERCI Daniel KHARLAMOV | 2018 | Chinese Journal of Aeronautics2018，31，4： | 2 |
| 6 | Targeting vectors for intracellular immunization显示文摘 | Persic L Righi M Roberts A | 1997 | Gene1997，187，： | 2 |
| 7 | Infrared spectroscopy of NH4^+- bearing and saturated clay minerals: a review of the study of layer charge显示文摘 | PETIT S RIGHI D MADEJOVA J | 2006 | Appl Clay Sci2006，34，14： | 1 |
| 8 | Serratia marcescens prosthesis infection successfully treated with meropenem after imipenem failure 显示文摘 | Lefort A Righi S Jaureguy F | 2005 | J Infect2005，51，2： | 1 |
| 9 | Gene regulatory networks and transcrip- tional mechanisms that control myogenesis显示文摘 | Buckingham M Righy PW | 2014 | Dev Cell2014，28，3： | 1 |
| 10 | Diagnostic imaging of bone metastases显示文摘 | Scutellari PN Addonisio G Righi M | 2000 | Radiol Med2000，100，6： | 1 |
| 11 | Emergency transjugular intrahepatic portosystemic shunt (TIPS): results, complications and predictors of mortality in the first month of follow-up 显示文摘 | Gazzera C Righi D Doriguzzi Breatta A | 2012 | Radiol Med2012，117，1： | 1 |
| 12 | Cyclic interface and joint shear de- vice including pore pressure erred'Is 显示文摘 | Desai C S Righy D B | 1997 | Journal of Geote- chnical and Geoenvironmental Engineering1997，123，6： | 1 |
| 13 | Analyzing the dependence structure of various sectors in the Brazilian market: A pair copula construction approach显示文摘 | Righi M B Ceretta P S | 2013 | Economic Mod- elling2013，35，： | 1 |
| 14 | Colistin and rifampiein in the treatment of multidrug - resistant Acinetobacter baumannii infections显示文摘 | Bassetti M Repetto E Righi E | 2008 | J Antimicrob Chemother2008，61，2： | 1 |
| 15 | Receptor for advanced glycation end product-dependent activation of p38 mitogen-activated protein kinase contributes to amyloid-β-mediated cortical synaptic dysfunction显示文摘 | Origlia N Righi M Capsoni S | 2008 | J Neurosci2008，28，13： | 1 |
| 16 | An improved control scheme for a series-capacitive reactance compensator based on a voltagesource inverter显示文摘 | Bruce S Righy Ronald G Harley | 1998 | IEEE Transaction on Applications1998，34，2： | 1 |
| 17 | Colistin and rifampicin in the treatment of multidrug-resistant Acinetobacter bauman?nii infections显示文摘 | Bassetti M Repetto E Righi E | 2008 | J Antimicrob Chemother2008，6，2： | 1 |
| 18 | Imaging features and clinical significance of perineural spread orextension of head and neck tumors显示文摘 | Caldemeyer K S Mathews V P Righi P D | 1998 | Radiographies1998，18，1： | 1 |
| 19 | Imaging features and clinical significance of perineural spread or extension of head and neck tumors显示文摘 | Caldemeyer KS Mathews VP Righi PD | 1998 | Radiographics1998，18，1： | 1 |
| 20 | Evaluating Terminal Management Performances Using SLAM: The Case of Athens International Airport 显示文摘 | ANDREATTA G BRUNETTA L RIGHI L | 2007 | Computers Operations Research2007，34，6： | 1 |
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