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5篇 您的检索式:作者名="REN Cuiling"
    题名 作者 年代 出处 被引量
1'Green' synthesis of starch capped CdSe nanoparticles at room temperature 显示文摘Li Jinhua Ren Cuiling Liu Xiaoyan 2007Materials Seience and Engineering A2007,458,:1
2Oxalate-degrading capacities of lactic acid bacteria in canine feces显示文摘REN Zhihua PAN Cuiling JIANG Luyan 0,,3:1
33DRGO-NiFe2O4/NiO nanoparticles for fast and simple detection of organophosphorus pesticides显示文摘The residues of organophosphorus pesticide(OPs)on fruits and vegetables pose a threat to human health,so it is very meaningful to explore simple and fast detect methods for OPs residual.In this work,nickel ferrite/nickel oxide nanoparticles co-loaded three-dimensional reduced graphene oxide(3DRGONiFe2O4/NiO NPs),as a new low cost nanocomposite,was prepared.Based on its high performance mimetic peroxidase activity,a colorimetric method for the detection of OPs has been developed.Dichlorvos was chosen as model compounds to evaluate the detection performance.The detection linear range for dichlorvos is from 50μg/mL to 2.5×10^4μg/mL with a detection limit of 10μg/mL.Furthermore,a test paper can be developed based on the 3 DRGO-NiFe2O4/NiO NPs for visual detection of dichlorvos,and the image information of the paper sensor can be converted into digital signal and quantitative detection by a smartphone.Notably,this method can also be used to detect dichlorvos in real samples,including vegetables and fruits.Thus,the developed naked assay holds great potential in simple,inexpensive and rapid detection of OPs in fruit and vegetable samples.Zhenni Wei Huiqing Li Jing Wu Yalei Dong Hongyi Zhang Hongli Chen Cuiling Ren 2020Chinese Chemical Letters2020,31,1:1
4A novel colorimetric determination of reduced glutathione in A549 cells based on Fe304 magnetic nanoparticles as peroxidase mimetics显示文摘MA Yanhua ZHANG Zhenyang REN Cuiling 2012Analyst2012,137,2:1
5Discovery of potential anti-SARS-CoV-2 drugs based on large-scale screening in vitro and effect evaluation in vivo显示文摘The coronavirus disease 2019(COVID-19)pandemic caused by severe acute respiratory syndrome coronavirus 2(SARSCoV-2)is a global crisis.Clinical candidates with high efficacy,ready availability,and that do not develop resistance are in urgent need.Despite that screening to repurpose clinically approved drugs has provided a variety of hits shown to be effective against SARS-CoV-2 infection in cell culture,there are few confirmed antiviral candidates in vivo.In this study,94 compounds showing high antiviral activity against SARS-CoV-2 in Vero E6 cells were identified from 2,580 FDA-approved small-molecule drugs.Among them,24 compounds with low cytotoxicity were selected,and of these,17 compounds also effectively suppressed SARS-CoV-2 infection in He La cells transduced with human ACE2.Six compounds disturb multiple processes of the SARSCoV-2 life cycle.Their prophylactic efficacies were determined in vivo using Syrian hamsters challenged with SARS-CoV-2infection.Seven compounds reduced weight loss and promoted weight regain of hamsters infected not only with the original strain but also the D614G variant.Except for cisatracurium,six compounds reduced hamster pulmonary viral load,and IL-6 and TNF-αm RNAwhen assayed at 4 d postinfection.In particular,sertraline,salinomycin,and gilteritinib showed similar protective effects as remdesivir in vivo and did not induce antiviral drug resistance after 10 serial passages of SARS-CoV-2 in vitro,suggesting promising application for COVID-19 treatment.Haoran Peng Cuiling Ding Liangliang Jiang Wanda Tang Yan Liu Lanjuan Zhao Zhigang Yi Hao Ren Chong Li Yanhua He Xu Zheng Hailin Tang Zhihui Chen Zhongtian Qi Ping Zhao 2022Science China(Life Sciences)2022,65,6:1
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