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| 1 | Alpha-fetoprotein expression is a potential prognostic marker in hepatocellular carcinoma显示文摘AIM: To characterize the alpha-fetoprotein (AFP) positive and negative hepatocellular carcinoma (HCC) samples.METHODS: Thirty-seven paraffin-embedded human HCC samples were analyzed by immunohistochemistry for the following antigens: AFP, β-catenin, p53, CD44, MSH-2,MLH-1, and HNF-4. The tumors were divided into two groups based on the AFP expression. The immunophenotypic data and important clinical parameters were studied between the two groups.RESULTS: Twenty-one of the thirty-seven examined HCCs were AFP positive. Seven with nuclear p53 staining were AFP positive, while seven tumors with nuclear β-catenin staining were AFP negative. CD44 staining and high histological tumor grade were more frequent among the AFP-positive HCCs. The other immunophenotypical and dinical parameters did not show statistically significant difference in their distribution between the AFP positive and negative samples.CONCLUSION: AFP expression in HCC correlates with unfavorable prognostic factors, while nuclear β-catenin positivity is more common among the AFP-negative liver tumors. This observation supports the microarray data onin vivo human tumors. | Dénes Grg János Regly-Mérei Sándor Paku László Kopper Péter Nagy | 2005 | World Journal of Gastroenterology2005，11，32： | 6 |
| 2 | Acute gouty synovitis associated with 'urate milk' 显示文摘 | FAM A G REIS M D SZALAI J P | 1997 | J Rheumatol1997，24，12： | 1 |
| 3 | Inhibins in female and male reproductive physiology:role in gametogenesis,conception,implantation and early pregnancy显示文摘 | Luisi S Florio P Reis FM | | 0，，02： | 1 |
| 4 | Lipases at interfaces: a review 显示文摘 | Reis P Holmberg K Watzke H | 2009 | Advances in Colloid and Interface Sci- ence2009，147，： | 1 |
| 5 | Vitamin D Status and Cardiovascular Health : a 2009 update 显示文摘 | Erin D Michos Jared P Reis Michal L Melamed | 2010 | The Open Clinical Chemistry Journal2010，3，： | 1 |
| 6 | Drilling carbon fiber reinforced plastics manufactured by autoclave-experimental and statistical study显示文摘 | Davim J P Reis P | 2003 | Materials&design2003，24，5： | 1 |
| 7 | Early adolescent participa- tion in physical activity: correlates with individual and family characteristics显示文摘 | MULHALL P REIS J BEGUM S | 2011 | J Phys Act Heal2011，8，： | 1 |
| 8 | Coherent control of pulsed X-ray beams显示文摘 | DeCamp M F Reis D A Bucksbaum P H | 2001 | Nature2001，413，6858： | 1 |
| 9 | Estimation Performance and Strategies Use of Mexican 5^th and 8^th Grade Student Sample 显示文摘 | Reys R E Reys B J Alfinio F P | 1991 | Educational Students in Mathematics1991，22，4： | 1 |
| 10 | Acute paraquat poisoning:report of a survival case following intake of a potential lethal dose显示文摘 | Dinis-Oliveira RJ Sarmento A Reis P | 2006 | Pediatr Emerg Care2006，22，7： | 1 |
| 11 | Expression and secretion of activin A:possible physiological and clinical implications显示文摘 | Luisi S Florio P Reis FM | 2001 | Eur J Endocrinol2001，145，4： | 1 |
| 12 | Aroma ageing trends in GC/MS profiles of liqueur wines显示文摘 | Pereira A C Reis M S Saraiva P M | 2010 | Anal Chim Acta2010，659，： | 1 |
| 13 | The role of dendritic cells in the induction and regulation of immunity to microbial infection显示文摘 | Reis e Sousa C Sher A Kaye P | 1999 | Curr Opin Immunol1999，11，： | 1 |
| 14 | Simple sequence repeats in Cucumis mapping and map merging显示文摘 | Danin P Y Reis N Baudracco A S | 2000 | Genome2000，43，： | 1 |
| 15 | Tailored Welded Blanks-an Experimental and Numerical Study in Sheet Metal Forming on the Effect of Welding显示文摘 | Reis A Teixeira P Ferreira D J | | 0，，： | 1 |
| 16 | Study of delamination in drilling carbon fiber reinforced plastics(CFRP)using design experiments显示文摘 | Davim J P Reis P | 2003 | Composite structures2003，59，4： | 1 |
| 17 | Acute paraquat poisoning:report of a survival case following intake of a potential lethal dose显示文摘 | DINIS-OLIVEIRA R J SARMENTO A REIS P | 2006 | Pediatr Emerg Care2006，22，7： | 1 |
| 18 | Advances in enhanced biological phosphorus removal:from micro to macro scale显示文摘 | Oehmen A Lemos P C Carvalho G Yuan Z Kelley J Blackall L L Reis M A M | 2007 | Water Research2007，41，11： | 1 |
| 19 | Solvent prop-erties governing protein partitioning in polymer/polymer a-queous two-phase systems显示文摘 | Madeira P P Reis C A Rodrigues A E | 2011 | Chromatogr A2011，1018，10： | 1 |
| 20 | Corticotrophin-releasing factor,Urocortin and endothelin-1 stimulate activin A release from cultured human placental cells显示文摘 | Reis F M Luisi S Florio P | 2002 | Placenta2002，23，6： | 1 |
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