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| 1 | Vitamin D improves inflammatory bowel disease outcomes:Basic science and clinical review显示文摘Vitamin D deficiency is commonly diagnosed among patients with inflammatory bowel disease(IBD).Patients with IBD are at risk of low bone density and increased fractures due to low vitamin D levels,long standing disease,and frequent steroid exposures;as a result,it is well established that vitamin D supplementation in this population is important.There is increasing support for the role of vitamin D in strengthening the innate immune system by acting as an immunomodulator and reducing inflammation in experimental and human IBD.The active form of vitamin D,1,25(OH)D3,acts on T cells to promote T helper(Th)2/regulatory T responses over Th1/Th17 responses;suppresses dendritic cell inflammatory activity;induces antibacterial activity;and regulates cytokine production in favor of an antiinflammatory response.Murine and human IBD studies support a therapeutic role of vitamin D in IBD.Risk factors for vitamin D deficiency in this population include decreased sunlight exposure,disease duration,smoking,and genetics.Vitamin D normalization is associated with reduced risk of relapse,reduced risk of IBD-related surgeries,and improvement in quality of life.Vitamin D is an inexpensive supplement which has been shown to improve IBD outcomes.However,further research is required to determine optimal serum vitamin D levels which will achieve beneficial immune effects,and stronger evidence is needed to support the role of vitamin D in inducing disease response and remission,as well as maintaining this improvement in patients’disease states. | Krista M Reich Richard N Fedorak Karen Madsen Karen I Kroeker | 2014 | World Journal of Gastroenterology2014，20，17： | 34 |
| 2 | 德国推进可再生能源良治研究显示文摘德国在可再生能源(RES)领域的先锋作用体现于它在风力发电和光伏发电装机能力的世界领先地位中,而且德国的生物燃料生产位居欧洲第一,安装的太阳能集热面积也很可观.这些成功不单是因为德国的自然资源基础优厚,而主要是创新的国家扶持政策的成果.来自欧洲和国际承诺的压力也对德国在可再生能源方面的成功做出了贡献.分析了德国可再生能源发展成功的原因,包括国家推广手段和扶持项目的优惠设计元素、欧洲和国际上对其政策的影响、技术和公众态度等环境条件的影响.另外进一步描述了其他欧洲国家可再生能源成功发展的驱动力,并探讨了德国可再生能源成功的驱动因素对于中国的适用性. | Mischa Bechberger Danyel Reiche | 2006 | 环境科学研究2006，19，B11： | 9 |
| 3 | Distance management of inflammatory bowel disease:Systematic review and meta-analysis显示文摘AIM:To review the effectiveness of distance management methods in the management of adult inflammatory bowel disease(IBD)patients.METHODS:A systematic review and meta-analysis of randomized controlled trials comparing distance management and standard clinic follow-up in the management of adult IBD patients.Distance management intervention was defined as any remote management method in which there is a patient self-management component whereby the patient interacts remotely via a self-guided management program,electronic interface,or self-directs open access to clinic follow up.The search strategy included electronic databases(Medline,PubMed,CINAHL,The Cochrane Central Register of Controlled Trials,EMBASE,KTPlus,Web of Science,and SCOPUS),conference proceedings,and internet search for web publications.The primary outcome was the mean difference in quality of life,and the secondary outcomes included mean difference in relapse rate,clinic visit rate,and hospital admission rate.Study selection,data extraction,and risk of bias assessment were completed by two independent reviewers.RESULTS:The search strategy identified a total of4061 articles,but only 6 randomized controlled trials met the inclusion and exclusion criteria for the systematic review and meta-analysis.Three trials involved telemanagement,and three trials involved directed patient self-management and open access clinics.The total sample size was 1463 patients.There was a trend towards improved quality of life in distance management patients with an end IBDQ quality of life score being 7.28(95%CI:-3.25-17.81)points higher than standard clinic follow-up.There was a significant decrease in the clinic visit rate among distance management patients mean difference-1.08(95%CI:-1.60--0.55),but no significant change in relapse rate or hospital admission rate.CONCLUSION:Distance management of IBD significantly decreases clinic visit utilization,but does not significantly affect relapse rates or hospital admission rates. | Vivian W Huang Krista M Reich Richard N Fedorak | 2014 | World Journal of Gastroenterology2014，20，3： | 9 |
| 4 | Envisat ASAR的区域森林——非森林制图显示文摘Envisat卫星ASAR传感器的双极化数据对区域森林监测十分有效。通过分别采用SRTM DEM和Landsat TM图像对地形起伏区域和平坦区域的SAR图像进行地理编码,发展了一种SAR图像自动预处理方法。基于冬季单时相ASAR数据的HH(水平发射,水平接收)、HV(水平发射,垂直接收)极化比值和HV极化图像,提出了一种面向对象的森林-非森林分类方法。将之应用于中国东北森林/非森林制图,分类总体精度、森林用户精度和生产者精度分别为83.7%,85.6%和75.7%。结果表明,本文提出的方法十分适合区域森林-非森林制图的业务化运行。 | 凌飞龙 李增元 陈尔学 黄燕平 田昕 SCHMULLIUS Christina LEITERER Reik REICHE Johannes SANTORO Maurizio | 2012 | 遥感学报2012，16，5： | 6 |
| 5 | 从定期安全性更新报告过渡到定期受益-风险评价报告:初步经验和挑战显示文摘人用药品注册技术要求国际协调会议(ICH)提供了定期安全性更新报告指南(PSUR,ICH E2C(R1))和新的定期受益-风险评价报告指南(PBRER,ICH E2C(R2))。PBRER由PSUR演变而来,实现了从比较传统的获批后药物警戒定期总结报告到现代定期受益-风险评价总结报告的转变,根据累积信息对批准上市产品做出最新的受益-风险评价。通过总结ICH E2C PSUR指南和PBRER指南的主要区别,介绍了某跨国制药公司在由编写PSUR改为编写PBRER的转变过程中所积累的初步经验及其遇到的挑战,讨论了中国在推进药物警戒系统的背景下实行PBRER的可能性。 | 张晓兰 Lester REICH 梁冰 Donald PUCCIO Craig HAR TFORD | 2014 | 中国药物警戒2014，11，4： | 3 |
| 6 | Biodiversity, Nitrogen Deposition, and CO2 Affect Grassland Soil Carbon Cycling but not Storage显示文摘 | Joseph Reid E. Adair Sarah Hobbie Peter Reich | 2012 | Ecosystems2012，，4： | 2 |
| 7 | Laparoscopic management of ovarian dennoid cysts显示文摘 | Reich H Mc Glynn F Sekei L | 1992 | The J of Reprod Med1992，37，： | 2 |
| 8 | Impaired IRS-1/PI3-kinase signaling in patients with HCV: A mechanism for increased prevalence of type 2 diabetes显示文摘 | Serhat Aytug David Reich Lawrence E. Sapiro David Bernstein Najma Begum | 2003 | Hepatology2003，，6： | 2 |
| 9 | Single nucleotide polymorphisms in genes associated with isoniazid resistance in mycobacterium tuberculosis显示文摘 | RAMASWAMY S V REICH R DOU S J | 2003 | Antimicrob Agents Chemother2003，47，： | 2 |
| 10 | 上海叙事:将城市针灸作为以社区为基础的遗产保护和发展策略显示文摘上海是一个进步与传统并存、现代化对城市肌理和本土社区不断冲击的地方。基于以上考虑,以上海虹口区提篮桥地区袖珍广场设计为例,采取城市针灸这种微干扰方式对该地区的公共空间体系进行整体性梳理,并在提升空间质量的过程中采取自下而上的社区参与模式,在落实设计时采取软硬设计相结合的方式以实现弹性空间的可能。'上海叙事'更多的是作为一种社区导向的、强调公众参与的、自下而上的规划模式探讨,而非简单的设计成果呈现,期望能对城市更新策略的探索尽绵薄之力。 | 单瑞琦 Michael Reiche Gaia Agostini | 2013 | 上海城市规划2013，，6： | 2 |
| 11 | Relationships of leaf dark respiration to leaf nitrogen, specific leaf area and leaf life-span: a test across biomes and functional groups显示文摘 | Peter B. Reich Michael B. Walters David S. Ellsworth James M. Vose John C. Volin Charles Gresham William D. Bowman | 1998 | Oecologia1998，，4： | 2 |
| 12 | Study on laser welding–brazing of zinc coated steel to aluminum alloy with a zinc based filler显示文摘 | C. Dharmendra K.P. Rao J. Wilden S. Reich | 2010 | Materials Science & Engineering A2010，，3： | 2 |
| 13 | Organic carbon in soils of the world显示文摘 | ESWARRAN H E VAN DEN BERG E V REICH P | 1993 | Soil Science Society of America Journal1993，57，： | 1 |
| 14 | Objective and subjective evaluation of the acoustic comfort in classrooms显示文摘 | Paulo Henrique Trombetta Zannin Carolina Reich Marcon | 2007 | Applied Ergonomics2007，，38： | 1 |
| 15 | Endometrial stromal sarcoma--observational evidence of a genetic background显示文摘 | Reich O Regauer S | 2005 | Eur J Gynaecol Oncol2005，26，3： | 1 |
| 16 | Radiofre- quency ablation of frequent, idiopathic premature ventricular complexes: Comparison with a control group without intervention显示文摘 | Bogun F Crawford T Reich S | 2007 | Heart Rhythm2007，4，7： | 1 |
| 17 | Global patterns of plant leaf N and P in relation to temperature and latitude显示文摘 | REICH P B OLEKSYN J | 2004 | PNAS2004，101，： | 1 |
| 18 | Relation-ship of leaf dark respiration to leaf-nitrogen specific leaf area andleaf life span:a test across biomes and functional groups显示文摘 | REICH P B WALTERS M B ELLSWORTH D S | 1998 | Oecologia1998，114，： | 1 |
| 19 | Haemodynamic responses to tracheal intubation following etomidate and fentang L for anaesthetic induction 显示文摘 | Leslie J Weiss bloom Davidl Reich | 1992 | Can J Anaesth1992，39，8： | 1 |
| 20 | The effect of multicolored machinable ceramics on the esthetics of all-ceramic crowns 显示文摘 | Reich S Horuberger H | 2002 | J Prosthet Dent2002，88，： | 1 |
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