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| 1 | Role of endoscopic ultrasonography in the loco-regional staging of patients with rectal cancer显示文摘The prognosis of rectal cancer(RC) is strictly related to both T and N stage of the disease at the time of diagnosis. RC staging is crucial for choosing the best multimodal therapy: patients with high risk locally advanced RC(LARC) undergo surgery after neoadjuvant chemotherapy and radiotherapy(NAT); those with low risk LARC are operated on after a preoperative short-course radiation therapy; finally, surgery alone is recommended only for early RC. Several imaging methods are used for staging patients with RC: computerized tomography, magnetic resonance imaging, positron emission tomography, and endoscopic ultrasound(EUS). EUS is highly accurate for the loco-regional staging of RC, since it is capable to evaluate precisely the mural infiltration of the tumor(T), especially in early RC. On the other hand, EUS is less accurate in restaging RC after NAT and before surgery. Finally, EUS is indicated for follow-up of patients operated on for RC, where there is a need for the surveillance of the anastomosis. The aim of this review is to highlight the impact of EUS on the management of patients with RC, evaluating its role in both preoperative staging and follow-up of patients after surgery. | Pietro Marone Mario de Bellis Valentina D'Angelo Paolo Delrio Valentina Passananti Elena Di Girolamo Giovanni Battista Rossi Daniela Rega Maura Claire Tracey Alfonso Mario Tempesta | 2015 | World Journal of Gastrointestinal Endoscopy2015，7，7： | 11 |
| 2 | Endoscopic approach to malignant strictures at the hepatic hilum显示文摘Hilar tumors have proven to be a challenge to treat and manage because of their poor sensitivity to conventional therapies and our inability to prevent or to detect early tumor formation. Endoscopic stent drainage has been proposed as an alternative to biliary-enteric bypass surgery and percutaneous drainage to palliate malignant biliary obstruction. Prosthetic palliation of patients with malignant hilar stenoses poses particular difficulties, especially in advanced lesions (type n lesions or higher). The risk of cholangitis after contrast injection into the biliary tree in cases where incomplete drainage is achieved is well known. The success rate of plastic stent insertion is around 80% in patients with proximal tumors. Relief of symptoms can be achieved in nearly all patients successfully stented. | Giovanni D De Palma Stefania Masone Maria Rega Immacolata Simeoli Francesca Salvatori Saverio Siciliano Francesco Maione Valerio Girardi Marta Celiento Giovanni Persico | 2007 | World Journal of Gastroenterology2007，13，30： | 8 |
| 3 | Conventional colonoscopy and magnified chromoendoscopy for the endoscopic histological prediction of diminutive colorectal polyps: A single operator study显示文摘瞄准:精确地由结肠镜检查把腺瘤区分开来与 non-adenomatous 息肉。方法:结肠镜检查检测的所有损害首先用多彩石印版内视镜检查法与放大跟随的常规看法被诊断。在每个步骤的诊断连续地被记录。所有息肉是为组织学的评估的完全移开的内视镜的联盟者。内视镜的诊断的每种类型的精确性率被评估,用象标准答案的组织检查所见。结果:240 损害的一个总数被识别,哪个(65.8%) 158 是非肿瘤的,(34.2%) 82 是腺瘤。常规看法的全面诊断精确性,和有放大的多彩石印版内视镜检查法是 76.3%(183/240 ) 并且 95.4%(229/240 ) ,分别地(P<0.001 ) 。结论:结肠镜检查和放大多彩石印版内视镜检查法的联合是为区分的最可靠的非活体检视方法从肿瘤的损害非肿瘤。 | Giovanni D De Palma Maria Rega Stefania Masone Marcello Persico Saverio Siciliano Pietro Addeo Giovanni Persico | 2006 | World Journal of Gastroenterology2006，12，15： | 3 |
| 4 | Metastatic tumors to the stomach: Clinical and endoscopicfeatures显示文摘AIM: To evaluate the clinical and endoscopic patterns in a large series of patients with metastatic tumors in the stomach. METHODS: A total of 64 patients with gastric meta- stases from solid malignant tumors were retros- pectively examined between 1990 and 2005. The clinicopathological findings were reviewed along with tumor characteristics such as endoscopic pattern, location, size and origin of the primary sites. RESULTS: Common indications for endoscopy were anemia, bleeding and epigastric pain. Metastases presented as solitary (62.5%) or multiple (37.5%) tumors were mainly located in the middle or upper third of stomach. The main primary metastatic tumors were from breast and lung cancer and malignant melanoma. CONCLUSION: As the prognosis of cancer patients has been improving gradually, gastrointestinal (GI) metastases will be encountered more often. Endoscopic examinations should be conducted carefully in patients with malignancies, and endoscopic biopsies and information on the patient’s clinical history are useful for correct diagnosis of gastric metastases. | Giovanni D De Palma Stefania Masone Maria Rega Immacolata Simeoli Mario Donisi Pietro Addeo Loredana Iannone Vincenzo Pilone Giovanni Persico | 2006 | World Journal of Gastroenterology2006，12，45： | 2 |
| 5 | Contrast-free endoscopic stent insertion in malignant biliary obstruction显示文摘AIM: To present a case series of MRCP-guided endoscopic biliary stent placement, performed entirely without contrast injection. METHODS: Contrast-free endoscopic biliary drainage was attempted in 20 patients with malignant obstruction, unsuitable for resection on the basis of tumor extent or medical illness. MRCP images were used to confirm the diagnosis of tumor, to exclude other biliary diseases and to demonstrate the stenoses as well as dilation of proximal liver segments. The procedure was carried out under conscious sedation. Patients were placed in the left lateral decubitus position. The endoscope was inserted, the papilla identified and cannulated by a papillotome. A guide wire was inserted and guided deeply into the biliary tree, above the stenosis, by fluoroscopy. A papillotomy approximately 1 cm. long was performed and the papillotome was exchanged with a guiding-catheter. A 10 Fr, Amsterdam-type plastic stent, 7 to 15 cm long, was finally inserted over the guide wire/ guiding catheter by a pusher tube system. RESULTS: Successful stent insertion was achieved in all patients. There were no major complications. Successful drainage, with substantial reduction in bilirubin levels, was achieved in all patients. CONCLUSION: This new method of contrast-free endoscopic stenting in malignant biliary obstruction is a safe and effective method of palliation. However, a larger, randomized study comparing this new approach with the standard procedure is needed to confirm the findings of the present study. | Giovanni D De Palma Giovanni Lombardi Maria Rega Immacolata Simeoli Stefania Masone Saverio Siciliano Francesco Maione Francesca Salvatori Antonio Balzano Giovanni Persico | 2007 | World Journal of Gastroenterology2007，13，29： | 2 |
| 6 | Actively bleeding Dieulafoy's lesion of the small bowel identified by capsule endoscopy and treated by push enteroscopy显示文摘Dieulafoy 的损害是周期性的官方补给的流血的一个不平常的原因。这份报告描述活跃地为 Dieulafoy 诊断被囊内视镜检查法在做的小肠的损害放血的一个案例,与推肠寄生物的使用由治疗列在后面。案例说明那囊内视镜检查法,肠寄生物在有小肠疾病的病人是高度补足的。 | Giovanni D De Palma Francesco Patrone Maria Rega Immacolata Simeoli Stefania Masone Giovanni Persico | 2006 | World Journal of Gastroenterology2006，12，24： | 2 |
| 7 | Modulating antimlcrobial activity by synthesis:Dendritic copolymers based on nonquater- nized 2-(dimethylamino)ethyl methacrylate by Cu-mediated ATRP显示文摘 | Vigliotta G Mella M Rega D | 2012 | Biomacromolecules2012，13，3： | 1 |
| 8 | Structure- based discovery of a new class of Bcl-XL antagonists 显示文摘 | REGA M F LEONE M JUNG D | 2007 | Bioorg Chem2007，35，4： | 1 |
| 9 | Characterisation of volatile compounds in Tunisian fenugreek seeds 显示文摘 | Mebazaa R Mahmoudi A Fouchet M Santos M D Kamissoko F Nafti A Cheikh R B Rega B Camel V | 2009 | Food Chemistry2009，115，4： | 1 |
| 10 | Non-heart-beating donors显示文摘 | VAN RAEMDONCK D E REGA F R NEYRINCK A P | 2004 | Semin Thorac Cardiovasc Surg2004，16，4： | 1 |
| 11 | Pancreatic endocrine tumors less than 4 cm in diameter: resect or enucleation? a single-center experience 显示文摘 | CASADEI R RICCI C REGA D | 2010 | Pancreas2010，39，6： | 1 |
| 12 | External cooling of warm ischemic rabbit lungs after death显示文摘 | Van Raemdonck D E Jannis N C Rega F R | 1996 | Ann Thorac Surg1996，62，2： | 1 |
| 13 | Performances of V2 O5-based Catalysts Obtained by Grafting Vanadyl Tri-isopropoxide on TiO2-SiO2 in SCR显示文摘 | Sorrentino A Rega S Sannino D | 2001 | Applied Catalysis A: General2001，209，： | 1 |
| 14 | Lower gastrointestinal bleeding secondary to a rectal leiomyoma显示文摘The occurrence of leiomyoma of the rectum is uncommon. Most of these lesions are clinically silent and are found incidentally during laparotomy or endoscopic procedures for unrelated conditions. Symptomatic leiomyomas of the rectum are encountered less frequently, with only sporadic reports in the literature. We describe a case of a leiomyoma of the rectum presenting as recurrent lower gastrointestinal hemorrhage and secondary anemia. | Giovanni D De Palma Maria Rega Stefania Masone Saverio Siciliano Marcello Persico Francesca Salvatori Francesco Maione Dario Esposito Antonio Bellino Giovanni Persico | 2009 | World Journal of Gastroenterology2009，15，14： | 1 |
| 15 | Structure- based discovery of a new class of Bcl-XL antagonists 显示文摘 | REGA M F LEONE M JUNG D | 2007 | Bioorg Chem2007，35，4： | 1 |
| 16 | Machine perfusion in organ transplantation: A tool for ex - vivo graft conditioning with mesenchymal stem cells? 显示文摘 | V AN RAEMDONCK D NEYRINCK A REGA F | 2013 | Curr Opin Organ Transplant2013，18，1： | 1 |
| 17 | Identification of the full-length huntingtin-interacting protein p231HBP/HYPB as a DNA-binding factor显示文摘 | REGA S STIEWE T CHANG D I | 2010 | Mol Cell Neurosci2010，18，： | 1 |
| 18 | Structure-based discovery of a new class of Bcl-xL antagonists显示文摘 | Rega MF Leone M Jung D | 2007 | Bioorg Chem2007，35，4： | 1 |
| 19 | Endoscopic management of intragastric penetrated adjustable gastric band for morbid obesity显示文摘这份报告与疾病的肥胖在一个病人描述胃内的渗透的可调节的胃的乐队的成功的内视镜的管理的一个案例。这里描述的案例的有利功课证明在移植的过程的可调节的胃的乐队不必在无征状的病人通过手术被移开。 | Giovanni D De Palma Antonio Formato Vincenzo Pilone Maria Rega Maria Elena Giuliano Immacolata Simeoli Pietro Forestieri | 2006 | World Journal of Gastroenterology2006，12，25： | 0 |
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