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| 1 | TREATMENT OF METALS, POLYMER FILMS, AND FABRICS WITHA ONE ATMOSPHERE UNIFORM GLOW DISCHARGE PLASMA(OAUGDP) FOR INCREASED SURFACE ENERGY AND DIRECTIONAL ETCHING显示文摘Direct exposure of samples to the active species of air generated by a One Atmosphere Uniform Glow Discharge Plasma (OAUGDP) has been used to etch and to increase the surface energy of metallic surfaces, photoresist, polymer films, and nonwoven fab- rics. The OAUGDP is a non-thermal plasma with the classical characteristics of a DC normal glow discharge that operates in air (and other gases) at atmospheric pres- sure. Neither a vacuum system nor batch processing is necessary. A wide range of applications to metals, photoresist, films, fabrics, and polymeric webs can be accom- modated by direct exposure of the workpiece to the plasma in parallel-plate reactors. This technolopy is simple, it produces effects that can be obtained in no other way at one atmosphere; it generates minimal pollutants or unwanted by-products; and it is suitable for individual sample or online treatment of metallic surfaces, wafers, films, and fabrics. Early exposures of solid materials to the OAUGDP required minutes to produce rela- tively small increases of surface energy. These durations appeared too long for com- mercial application to fast-moving webs. Recent improvements in OAUGDP gas com- position, power density, plasma quality, recireulating gas flow, and impedance match- ing of the power supply to the parallel plate plasma reactor have made it possible to raise the surface energy of a variety of polymeric webs (PP, PET PE etc.) to levels of 60 to 70 dynes/cm with one second of exposure. In air plasmas, the high surface ener- gies are not durable, and fall to 50 dynes/cm after periods of weeks to months. Here, we report the exposure of metallic surfaces, photoresist, polymeric films, and nonwo- ven fabrics made of PP and PET to an impedance matched parallel plate OAUGDP for durations ranging from one second to several tens of seconds. Data will be re- ported on the surface energy, wettability, wickability, and aging effect of polymeric films and fabrics as functions of time of exposure, and time after exposure; the rate and uniformity of photoresist etching; and the production of sub-micron structures by OAUGDP etching at one atmosphere. | J. Reece Roth and Z. Y Chen (Plasma Sciences Laboratory, Department of Electrical and Computer Engineering, University of Tennessee, Knoxville, TN 37996-2100, USA) Peter P.- Y Tsai (Textiles and Nonwovens Development Center (TANDEC), University of Tenness | 2001 | Acta Metallurgica Sinica(English Letters)2001，14，6： | 18 |
| 2 | 妊娠合并糖尿病诱发胚胎先天性神经管缺陷的MAP激酶及细胞凋亡信号传导机制显示文摘目的 :探讨妊娠合并糖尿病诱发胚胎先天性神经管缺陷的分子机制。方法 :将雌性SD大鼠分为 3组 :第 1组为正常对照组 ;第 2组为streptozotocin (STZ)构建的妊娠合并糖尿病诱发先天性神经管缺陷的实验组 ;第 3组为STZ构建的糖尿病大鼠模型 ,胚胎不伴有先天性神经管缺陷。于妊娠第 1 2天取出各组胚胎 ,解剖显微镜下进行形态学分析 ;对卵黄囊细胞进行DNA片段分析 ;提取卵黄囊细胞蛋白质 ,应用特异性抗磷酸化抗体进行免疫共沉淀及Westernblot对MAPkinase(MAPK)信号途径上各蛋白激酶活性进行分析。结果 :第 2组中 ,卵黄囊细胞出现细胞凋亡特征性的DNAladder,与正常对照组相比ERK1 /2蛋白激酶活性显著下降 ;与此相反 ,JNK1 /2活性明显升高 ,凋亡相关基因caspase 3、Bax高表达 ,凋亡抑制基因AKT活性明显受抑。结论 :糖尿病诱发的胚胎先天性神经管缺陷的发生 。 | 马向东 陈必良 辛晓燕 王德堂 E.Albert Reece | 2003 | 现代妇产科进展2003，12，5： | 15 |
| 3 | Birth defects in pregestational diabetes:Defect range,glycemic threshold and pathogenesis显示文摘Currently,60 million women of reproductive age(18-44 years old) worldwide,and approximately 3 million American women have diabetes mellitus,and it has been estimated that this number will double by 2030.Pregestational diabetes mellitus(PGD) is a significant public health problem that increases the risk for structural birth defects affecting both maternal and neonatal pregnancy outcome.The most common types of human structural birth defects associated with PGD are congenital heart defects and central nervous system defects.However,diabetes can induce birth defects in any other fetal organ.In general,the rate of birth defects increases linearly with the degree of maternal hyperglycemia,which is the major factor that mediates teratogenicity of PGD.Stringent prenatal care and glycemic control are effective means to reduce birth defects in PGD pregnancies,but cannot reduce the incidence of birth defects to the rate of that is seen in the nondiabetic population.Studies in animal models have revealed that PGD induces oxidative stress,which activates cellular stress signalling leading to dysregulation of gene expression and excess apoptosis in the target organs,including the neural tube and embryonic heart.Activation of the apoptosis signalregulating kinase 1(ASK1)-forkhead transcription factor 3a(Fox O3a)-caspase 8 pathway causes apoptosis in the developing neural tube leading to neural tube defects(NTDs).ASK1 activates the c-Jun-N-Terminal kinase 1/2(JNK1/2),which leads to activation of the unfolded protein response and endoplasmic reticulum(ER) stress.Deletion of the ASK1 gene,the JNK1 gene,or the JNK2 gene,or inhibition of ER stress by 4-Phenylbutyric acid abrogates diabetes-induced apoptosis and reduces the formation of NTDs.Antioxidants,such as thioredoxin,which inhibits the ASK1-Fox O3a-caspase 8 pathway or ER stress inhibitors,may prevent PGD-induced birth defects. | Rinat Gabbay-Benziv E Albert Reece Fang Wang Peixin Yang | 2015 | World Journal of Diabetes2015，6，3： | 10 |
| 4 | 妊娠合并糖尿病诱发胚胎先天性神经管缺陷动物模型的MAP激酶信号传导机制显示文摘为了揭示妊娠合并糖尿病诱发胚胎先天性神经管缺陷的分子机制,并探讨其有效的防治方法。实验选用6个实验组的Sprague Dawley大鼠:第1组为常规饲养的正常对照组;第2组尾静脉注射65mg/kgStreptozotocin(STZ)构建妊娠合并糖尿病、且诱发先天性神经管缺陷的实验组大鼠;第3组为STZ构建的糖尿病、但胚胎不伴有先天性神经管缺陷的大鼠模型;第4、5、6组为STZ构建的糖尿病治疗组大鼠,每日分别给予80μg/mL花生四烯酸(arachidonicacid,AA)、400mg维生素E、抗氧化剂(维生素E)和不饱和脂肪酸(safloweroil)混合物cocktail治疗。于妊娠第12天取出各组胚胎,解剖显微镜下进行形态学分析;提取卵黄囊细胞蛋白质,应用特异性抗磷酸化抗体进行免疫共沉淀及Western印迹,对MAP激酶信号途径上各蛋白激酶ERK1/2、JNK1/2、RAF 1活性进行分析。与正常对照组相比,妊娠合并糖尿病诱发的先天性神经管缺陷胚胎中(第2组),ERK1/2蛋白激酶活性显著下降,其上游RAF 1活性相应降低;与此相反,JNK1/2活性明显升高。在给予花生四烯酸、维生素E补充物治疗后,通过调节MAP激酶信号通路蛋白激酶活性,逆转了胚胎神经管缺陷的发生。妊娠合并糖尿病诱发的胚胎先天性神经管缺陷的发生,与MAP激酶信号传导机制异常密切相关。 | 陈必良 马向东 辛晓燕 王德堂 E.Albert Reece M.D. | 2004 | 遗传2004，26，5： | 7 |
| 5 | BCL2 inhibits cell adhesion, spreading, and motility by enhancing actin polymerization显示文摘BCL2 最好作为多功能的 anti-apoptotic 蛋白质被知道。然而,很少在房间粘合剂和活动性事件对它的角色被知道。这里,我们证明 BCL2 可以在房间粘附的规定起一个作用,传播,并且活动性。BCL2 什么时候是在有教养的鼠科、人的房间线,传播的房间,粘附,和活动性的 overexpressed,被损害。与这些结果一致, Bcl2 的损失导致了在 Bcl2 空的老鼠观察的更高的活动性与野类型相比的胚胎的成纤维细胞(MEF ) 房间。房间粘附和活动性的 BCL2 规定的机制可以包含包含 BCL2,肌动朊,和 gelsolin 的建筑群的形成,它看起来机能上地减少 gelsolin 的切断的活动。我们观察到从 overexpressed BCL2 提高了的 MCF-7 和 NIH3T3 房间的 lysate 肌动朊聚合在在 vitro 试金没有房间。BCL2 和 F 肌动朊的共焦的 immunofluorescent 本地化在一致地传播期间证明 BCL2 的那增加的表情导致了增加的 F 肌动朊聚合。因此, BCL2 和 gelsolin 建筑群的形成(它可能包含另外的蛋白质) 看起来在房间粘附和移植的规定起一个关键作用。与癌症转移给房间活动性的确定的关联,这结果可以解释在一些肿瘤房间类型的 BCL2 的表示为什么为转移减少潜力并且与改进耐心的预后被联系。 | Hengning Ke Vandy I Parron Jeff Reece Jennifer Y Zhang Steven K Akiyama John E French | 2010 | Cell Research2010，20，4： | 3 |
| 6 | Anterior cruciate ligament reconstruction using a double bundle hamstring autograft configuration in patients under 30 years显示文摘BACKGROUND Anterior cruciate ligament reconstruction(ACLR)has a high incidence of re-tear in younger patients.Despite comparable functional outcomes,the incidence of retear using single and double bundle ACLR methods has not been well reported.AIM To hypothesize that double bundle hamstring ACLR has a lower graft rupture rate compared with single bundle hamstring ACLR grafts in young patients.METHODS One hundred and twelve patients<30 years of age at the time of primary double bundle ACLR were eligible for study participation.91(81.3%)could be contacted,with a mean age of 20.4 years(range 13-29)and mean post-operative follow-up time of 59 mo(range 25-107).Telephone questionnaires evaluated the incidence(and timing)of subsequent re-tear and contralateral ACL tear,further surgeries,incidence and time to return to sport,and patient satisfaction.RESULTS Of the 91 patients,there were 6(6.6%,95%CI:1.4-11.7)ACL graft re-ruptures,with a mean time to re-rupture of 28 mo(range 12-84).Fourteen patients(15.4%)experienced a contralateral ACL rupture and 14 patients(15.4%)required further surgery to their ipsilateral knee.fifty patients(54.9%)returned to pre-injury level of sport.Of those<20 years(n=45),4 patients(8.9%,95%CI:0.4-17.3)experienced a re-rupture,with mean time to re-injury 15 mo(range 12-24).Comparative analysis with existing literature and revealed a non-significant Chisquared statistic of 2.348(P=0.125).CONCLUSION A trend existed toward lower graft rupture rates in young patients undergoing double bundle ACLR utilizing a hamstring autograft,compared with rates reported after single bundle ACLR. | Christopher Reece Lim Tamalee Henson Jay Ebert Peter Annear | 2019 | World Journal of Orthopedics2019，10，12： | 2 |
| 7 | Lack of periconceptional vitamins or supplements that contain folic acid and diabetes mellitus–associated birth defects显示文摘 | Adolfo Correa Suzanne M. Gilboa Lorenzo D. Botto Cynthia A. Moore Charlotte A. Hobbs Mario A. Cleves Tiffany J. Riehle-Colarusso D. Kim Waller E. Albert Reece | 2012 | American Journal of Obstetrics and Gynecology2012，，3： | 2 |
| 8 | 2011 Update to The Society of Thoracic Surgeons and the Society of Cardiovascular Anesthesiologists Blood Conservation Clinical Practice Guidelines ? ? The International Consortium for Evidence Based Perfusion formally endorses these guidelines.显示文摘 | Victor A. Ferraris Jeremiah R. Brown George J. Despotis John W. Hammon T. Brett Reece Sibu P. Saha Howard K. Song Ellen R. Clough Linda J. Shore-Lesserson Lawrence T. Goodnough C. David Mazer Aryeh Shander Mark Stafford-Smith Jonathan Waters Robert A. Bak | 2011 | The Annals of Thoracic Surgery2011，，3： | 2 |
| 9 | Use of the Diversi Lab System for species and strain differentiation of Fusarium species isolates显示文摘 | Healy M Reece K Walton D | 2005 | J Clin Microbiol2005，43，10： | 1 |
| 10 | Acute and subacute effects of naturally occurring estrogens on luteinizing hormone secretion in the ovariectomised rat: part 2 显示文摘 | Hughes C L Chakinala M M Reece S G | 1991 | Reprod Toxicol1991，5，： | 1 |
| 11 | Progress in the development of a Reynolds-Stress Turbulence Closure显示文摘 | LAUNDER B E REECE G J RODI W | 1975 | J Fluid Mech1975，68，3： | 1 |
| 12 | Combined intrau- terine and extrauterine gestations:a review 显示文摘 | Reece EA Petrie RH Sirmans MF | 1983 | Am J Ob- stet Gynecol1983，146，3： | 1 |
| 13 | Mitochondrial glutathione modulates TNFa-induced endothelial cell dysfunction显示文摘 | Chen KH Reece LM Leary JF | 1999 | FreRad Biol Med1999，27，1： | 1 |
| 14 | Choice of flap and incidence of free flap success显示文摘 | Kroll SS Schusterman MA Reece GP | 1996 | Plast Reconstr Surg1996，98，： | 1 |
| 15 | Symmetrical three dimensional soil failure显示文摘 | Hettiaratchi D R P Reece A R | 1967 | Journal of Terramechanics1967，4，3： | 1 |
| 16 | Sonographic assessment of the distal femoral and proximal tibial ossification centers in the prediction of pulmonic maturity in normal women and women with diabetes显示文摘 | Goldstein I Lockwood CJ Reece EA | | 0，，01： | 1 |
| 17 | Control of rabies in Jaipur, India, by the sterilisation and vaccination of neighbourhood dogs显示文摘 | Reece JF Chawla SK | 2006 | Vet Rec2006，159，12： | 1 |
| 18 | Effects of high temperature and humidity on heat prostration of broiler chickens 显示文摘 | REECE F N DEATON J W KUBENA L F | 1972 | Poultry Science1972，51，6： | 1 |
| 19 | CD4 ( + )T-cell immune response to a conserved epitope in the circumsponrozoite protein correlates with protection from natural Plasmodium falciparum infection and disease 显示文摘 | Reece W H | 2004 | Nat Med2004，10，： | 1 |
| 20 | Response of mean annual evapotranspiration to vegetation changes at catchment scale 显示文摘 | Zhang L Dawas W R Reece P H | 2001 | Water Resource Research2001，37，3： | 1 |
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