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| 1 | 国际胃袖状切除专家共识:基于>12000手术病例的最佳操作指南显示文摘腹腔镜胃袖状切除术(1aparoscopic sleeve gastrectomy,LSG)系相对较新的减重手术方式。因其操作相对简单、治疗肥胖合并疾病及减重效果明显,逐步得以广泛接受。目前美国代谢与减重手术协会将其推荐为肥胖症治疗的单独标准术式。2011年3月25~26日, | 苏远涛 徐安安 朱江帆 Diaz AA Arvidsson D Baker RS Basso N Bellanger D Boza C El Mourad H France M Gagner M Galvao-Neto M Higa KD Himpens J Hutchinson CM Jacobs M Jorgensen JO Jossart G Lakdawala M Nguyen NT Nocca D Prager G Pomp A Ramos AC Rosenthal RJ Shah S Vix M Wittgrove A Zundel N | 2013 | 中国微创外科杂志2013，13，9： | 12 |
| 2 | Quality of life, work productivity impairment and healthcare resources in inflammatory bowel diseases in Brazil显示文摘BACKGROUND Inflammatory bowel diseases(IBD)have been associated with a low quality of life(QoL)and a negative impact on work productivity compared to the general population.Information about disease control,patient-reported outcomes(PROs),treatment patterns and use of healthcare resources is relevant to optimizing IBD management.AIM To describe QoL and work productivity and activity impairment(WPAI),treatment patterns and use of healthcare resources among IBD patients in Brazil.METHODS A multicenter cross-sectional study included adult outpatients who were previously diagnosed with moderate to severe Crohn’s disease(CD)or ulcerative colitis(UC).At enrolment,active CD and UC were defined as having a Harvey Bradshaw Index≥8 or a CD Activity Index≥220 or calprotectin>200μg/g or previous colonoscopy results suggestive of inadequate control(per investigator criteria)and a 9-point partial Mayo score≥5,respectively.The PRO assessment included the QoL questionnaires SF-36 and EQ-5D-5L,the Inflammatory Bowel Disease Questionnaire(IBDQ),and the WPAI questionnaire.Information about healthcare resources and treatment during the previous 3 years was collected from medical records.Chi-square,Fisher’s exact and Student’s t-/Mann-Whitney U tests were used to compare PROs,treatment patterns and the use of healthcare resources by disease activity(α=0.05).RESULTS Of the 407 patients in this study(CD/UC:64.9%/35.1%,mean age 42.9/45.9 years,54.2%/56.6%female,38.3%/37.1%employed),44.7%/25.2%presented moderate-to-severe CD/UC activity,respectively,at baseline.Expressed in median values for CD/UC,respectively,the SF-36 physical component was 46.6/44.7 and the mental component was 45.2/44.2,the EQ-visual analog scale score was 80.0/70.0,and the IBDQ overall score was 164.0/165.0.Moderate to severe activity,female gender,being unemployed,a lower educational level and lower income were associated with lower QoL(P<0.05).Median work productivity impairment was 20%and 5%for CD and UC patients,respectively,and activity impairment was 30%,the latter being higher among patients with moderate to severe disease activity compared to patients with mild or no disease activity(75.0%vs 10.0%,P<0.001).For CD/UC patients,respectively,25.4%/2.8%had at least one surgery,38.3%/19.6%were hospitalized,and 70.7%/77.6%changed IBD treatment at least once during the last 3 years.The most common treatments at baseline were biologics(75.3%)and immunosuppressants(70.9%)for CD patients and 5-ASA compounds(77.5%)for UC patients.CONCLUSION Moderate to severe IBD activity,especially among CD patients,is associated with a substantial impact on QoL,work productivity impairment and an increased number of IBD surgeries and hospitalizations in Brazil. | Rogerio Serafim Parra Julio MF Chebli Heda MBS Amarante Cristina Flores Jose ML Parente Odery Ramos Milene Fernandes Jose JR Rocha Marley R Feitosa Omar Feres Antonio S Scotton Rodrigo B Nones Murilo M Lima Cyrla Zaltman Carolina D Goncalves Isabella M Guimaraes Genoile O Santana Ligia Y Sassaki Rogerio S Hossne Mauro Bafutto Roberto LK Junior Mikaell AG Faria Sender J Miszputen Tarcia NF Gomes Wilson R Catapani Anderson A Faria Stella CS Souza Rosana F Caratin Juliana T Senra Maria LA Ferrari | 2019 | World Journal of Gastroenterology2019，25，38： | 2 |
| 3 | CD14,a receptor for complexes of lipopolysaccharide (LPS) and LPS binding protein显示文摘 | Wright S D Ramos R A Tobias P S | 1990 | Science1990，249，4975： | 2 |
| 4 | Goal programming approach to maintenance scheduling of generating unit in large scale power systems显示文摘 | Andrés Ramos | 1999 | IEEE Trans on Power Systems1999，14，3： | 1 |
| 5 | Analytical and mineralogical studies of ore and impurities from a chromite mineral using X - ray analysis, electrochemical and microscopy techniques 显示文摘 | Ramos S S Carbo A D Adelantado J V | 2008 | Talanta2008，74，5： | 1 |
| 6 | First report of CTX-M producing Escherichia coli , including the new ST2526, isolated from beef cattle and sheep in Portugal显示文摘 | Sónia Ramos Gilberto Igrejas Nuno Silva Daniela Jones-Dias José-Luís Capelo-Martinez Manuela Cani?a Patrícia Poeta | 2013 | Food Control2013，，1： | 1 |
| 7 | Leakage detection and location in gas pipelines through an LPV identification approach显示文摘 | Lopes S P Azevedo T P Ramos J A | 2011 | C in Nonlinear Science and Numerical Simulation2011，12，16： | 1 |
| 8 | Synthesis and Fixation of Aminocyanines to Microcrystalline Cellulose Using Cyanuric Chloride as a Cross-linking Agent显示文摘 | Ramos S S Santos L | 2001 | Coloration Technology2001，117，1： | 1 |
| 9 | An LPV modeling and identification approach to leakage detection in high pressure natural gas transportation networks显示文摘 | Lopes S P Ramos J A Carvalhs J L | 2011 | IEEE Transactions on Control Systems Technology2011，19，1： | 1 |
| 10 | Comparative structural analysis of et-glucosidase inhibitors on difference species: a computational study 显示文摘 | Narayana Moorthy N S Ramos M J Fernandes P A | 2012 | Arch Pharm (Weinheim)2012，345，4： | 1 |
| 11 | Influence of fatty acid composition of raw materials on biodiesel properties显示文摘 | MARíA JESúS RAMOS CARMEN MARíA FERNANDEZ ABRAHAM CASAS | 2009 | Bioresource Technology2009，100，1： | 1 |
| 12 | The N-terminus of the fragile X mental retardation protein contains a novel domain involved in dimerization and RNA binding显示文摘 | ADINOLFI S RAMOS A MARTIN SR | 2003 | Biochemistry2003，42，10： | 1 |
| 13 | Effect of water activity and temperature on growth and ochratoxin production by three strains of Aspergillus ochraeeus on an barley extract medium and onbarley grains 显示文摘 | Ramos A J Lavernia N Marin S | 1998 | Food Microbiol1998，44，12： | 1 |
| 14 | The structure of the N-terminal domain of the fragile X mental retardation protein:a platform for protein-protein interaction显示文摘 | RAMOS A HOLLINGWORTH D Adinolfi S | 2006 | Structure2006，14，： | 1 |
| 15 | Transverse myelitis affect- ing more than 4 spinal segments associated with systemic lupus erythematosus: clinical, immunological, and radiological characteristics of 22 patients 显示文摘 | Espinosa G Mendizabal A Minguez S Ramo - Tello C Capellades J Olive A Cervera R | 2010 | Semin Arthritis Rheum2010，39，4： | 1 |
| 16 | Phylogeography of the endangered rosewood Dalbergia nigra (Fabaceae): insights into the evolutionary history and conservation of the Brazilian Atlantic Forest显示文摘 | Ribeiro R A Lemos J P Ramos A C S | 2011 | Heredity2011，106，： | 1 |
| 17 | Southern Patagonian Plateau basalts and deformation: Baekarc testimony of ridge collision显示文摘 | Ramos V A Kay S M | 1992 | Tectonophysics1992，205，： | 1 |
| 18 | Antihypertensive activity of milk fermented by Enterococcus faecalis strains isolated from raw milk显示文摘 | MUGUERZA B RAMOS M S(A)NCHEZ E | | 0，，01： | 1 |
| 19 | In silico analysis of accurate proteomics, complemented by selective isolation of pep- tides显示文摘 | Y Perez - Riverol A S Nchez Y Ramos | 2011 | Journal of Proteomics2011，74，10： | 1 |
| 20 | Upper lip changes correlated to maxillary incisor retraction-a metallic implant study 显示文摘 | Ramos A L Sakima M T Pinto-Ados S | 2005 | Angle Orthod2005，75，4： | 1 |
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