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| 1 | 气象卫星云图的多分辨小波分解及人工神经网络降水估计研究显示文摘采用多分辨小波分析对卫星图象进行预处理 ,在保留其特征信息的同时 ,减小了数据量 ,改善了神经网络训练过程的收敛性能 ,提高了处理速度。采用这一方法根据 GOES- 8的红外亮温图象和气象雷达资料对巴西圣保罗州中部的降水量估计进行了试验 ,取得了良好的效果。 | 李伟钢 Maria C V Ramirez Nelson J Ferreira 石立华 Leonardo D de A Sá | 2000 | 南京气象学院学报2000，23，2： | 13 |
| 2 | Pharmacogenomics in colorectal cancer: The first step for individualized-therapy显示文摘Interindividual differences in the toxicity and response to anticancer therapies are currently observed in practically all available treatment regimens. A goal of cancer therapy is to predict patient response and toxicity to drugs in order to facilitate the individualization of patient treatment. Identification of subgroups of patients that differ in their prognosis and response to treatment could help to identify the best available drug therapy according the genetic profile. Several mechanisms have been suggested to contribute to chemo-therapeutic drug resistance: amplification or overexpression of membrane transporters, changes in cellular proteins involved in detoxification or in DNA repair, apoptosis and activation of oncogenes or tumor suppressor genes. Colorectal cancer (CRC) is regarded as intrinsically resistant to chemotherapy. Several molecular markers predictive of CRC therapy have been included during the last decade but their results in different studies complicate their application in practical clinical. The simultaneous testing of multiple markers predictive of response could help to identify more accurately the true role of these polymorphisms in CRC therapy. This review analyzes the role of genetic variants in genes involved in the action mechanisms of the drugs used at present in colorectal cancer. | Eva Bandrés Ruth Zárate Natalia Ramirez Ana Abajo Nerea Bitarte Jesus García-Foncillas | 2007 | World Journal of Gastroenterology2007，13，44： | 4 |
| 3 | A techno-economic and life cycle assessment for the production of green methanol from CO_(2): catalyst and process bottlenecks显示文摘The success of catalytic schemes for the large-scale valorization of CO_(2) does not only depend on the development of active,selective and stable catalytic materials but also on the overall process design.Here we present a multidisciplinary study(from catalyst to plant and techno-economic/lifecycle analysis)for the production of green methanol from renewable H2 and CO_(2).We combine an in-depth kinetic analysis of one of the most promising recently reported methanol-synthesis catalysts(InCo)with a thorough process simulation and techno-economic assessment.We then perform a life cycle assessment of the simulated process to gauge the real environmental impact of green methanol production from CO_(2).Our results indicate that up to 1.75 ton of CO_(2) can be abated per ton of produced methanol only if renewable energy is used to run the process,while the sensitivity analysis suggest that either rock-bottom H2 prices(1.5$kg1)or severe CO_(2) taxation(300$per ton)are needed for a profitable methanol plant.Besides,we herein highlight and analyze some critical bottlenecks of the process.Especial attention has been paid to the contribution of H2 to the overall plant costs,CH4 trace formation,and purity and costs of raw gases.In addition to providing important information for policy makers and industrialists,directions for catalyst(and therefore process)improvements are outlined. | Tomas Cordero-Lanzac Adrian Ramirez Alberto Navajas Lieven Gevers Sirio Brunialti Luis MGandía Andrés T.Aguayo S.Mani Sarathy Jorge Gascon | 2022 | Journal of Energy Chemistry2022，31，5： | 3 |
| 4 | Moving forward in colorectal cancer research, what proteomics has to tell显示文摘Colorectal cancer is the third most common cancer and is highly fatal. During the last several years, research has been primarily based on the study of expression profiles using microarray technology. But now, investigators are putting into practice proteomic analyses of cancer tissues and cells to identify new diagnostic or therapeutic biomarkers for this cancer. Because the proteome reflects the state of a cell, tissue or organism more accurately, much is expected from proteomics to yield better tumor markers for disease diagnosis and therapy monitoring. This review summarizes the most relevant applications of proteomics the biomarker discovery for colorectal cancer. | Nerea Bitarte Eva Bandrés Ruth Zárate Natalia Ramirez Jesus Garcia-Foncillas | 2007 | World Journal of Gastroenterology2007，13，44： | 3 |
| 5 | Urinary kidney injury molecule-l: a sensitive quantitative biomarker for early detection of kidney tubular injury 显示文摘 | Vaidya V S Ramirez V Ichimura T | 2006 | Am J Physiol Renal Physiol2006，290，2： | 1 |
| 6 | U- rinary kidney injury mol-ecule-l:a sensitive quantita- tive biomarker for early detection of kid-ney tubular injury显示文摘 | VAIDYA V S RAMIREZ V ICHIMURA T | 2006 | Am J Physiol Renal Physiol2006，290，： | 1 |
| 7 | Effect of nozzle orifice geometry on spray, combustion, and emission characteristics under diesel engine conditions显示文摘 | Som S Ramirez A I Longman D E | 2011 | Fuel2011，90，3： | 1 |
| 8 | Early switch from intravenous to oral cephalosporins in the treatment of hospitalized patients with community- acquired pneumonia 显示文摘 | Ramirez JA Srinath L Ahkes S | 1995 | Arch Intern Med1995，155，12： | 1 |
| 9 | Transient elastography to rule out esophageal varices and portal hypertensive gastropathy in HIV-infected individuals with liver cirrhosis显示文摘 | Maria L. Montes Ramirez Jose F. Pascual-Pareja Matilde Sánchez-Conde Jose I. Bernardino De la Serna Francisco X. Zamora Vargas Pilar Miralles Juan M. Castro Margarita Ramírez Isabel Gutierrez Juan Gonzalez-García Juan Berenguer Jose R. Arribas López | 2012 | AIDS2012，，14： | 1 |
| 10 | Metal thbrication by ad- ditive manuthcturing using laser and electron beam melting technol- ogies显示文摘 | Muir L E Gaytan S M Ramirez D A | 2012 | J Material Science and Technology2012，28，1： | 1 |
| 11 | Incompletely condensed fluoroalkyl silsesquioxanes and derivatives:Precursors for low surface energy materials显示文摘 | RAMIREZ S M DIAZ Y J CAMPOS R | 2011 | Journal of the American Chemical Society2011，133，20： | 1 |
| 12 | A review of wind speed probability distributions used in wind energy analysis 显示文摘 | Carta J Ramirez P Velazquez S | 2009 | Renewable and Sustainable Energy Reviews2009，13，5： | 1 |
| 13 | Utilization of oxygen uptake rate to assess the role of glucose and glutamine in the metabolism of infected insect cell cultures显示文摘 | Palomares L A Lopez S Ramirez O T | 2004 | Biochemical Engineering Journal2004，19，1： | 1 |
| 14 | New microsatellite resources for groupers(Serranidae)显示文摘 | Ramirez M A Patricia A J Planas S | 2006 | Molecular Ecology Notes2006，6，3： | 1 |
| 15 | Electrochemotherapy on liver tumor rabbits 显示文摘 | Ramirez LH Orlowski S An D | 1998 | Br J Cancer1998，77，12： | 1 |
| 16 | The influence of eollagen-glycosaminoglyean scaffold relative density and microstructural anisotropy on tenocyte bioactivity and transcriptomic stability 显示文摘 | CALIARI S R WEISGERBER D W RAMIREZ M A | 2012 | J Mech Behav Biomed Ma- ter2012，11，11： | 1 |
| 17 | In vitro and in vivo adenovirus mediated P53 and p16 tumor suppressor therapy in ovarian cancer 显示文摘 | MODESITT S C RAMIREZ P ZU Z | 2001 | Clin Cancer Res2001，7，： | 1 |
| 18 | Synthesisand applications of one-dimensional semiconductors显示文摘 | BARTH S RAMIREZ F H HOLMES J D | 2010 | Progressin Materials Science2010，55，6： | 1 |
| 19 | HIV - 1 Tat - mediated activation of glycogen synthase kinase - 3beta contributes to Tat - mediated neurotoxicity 显示文摘 | MAGGIRWAR S B TONG N RAMIREZ S | 1999 | J Neurochem1999，73，2： | 1 |
| 20 | Microstructure evolution associated with adiabatic shear bands and shear band failure in baUistic plug formation in Ti-6A1-4V targets 显示文摘 | Murr L E Ramirez A C Gaytan S M Lopez M I Martinez E Y Hernandez D H Martinez E | 2009 | Materials Science and Engineering A2009，516，： | 1 |
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