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| 1 | The role of estradiol in male reproductive function显示文摘传统地,睾丸激素和雌激素被认为分别地是男、女的性荷尔蒙。然而, estradiol,雌激素的占优势的表格,也在男性功能起一个关键作用。在人的 Estradiol 为 modulating 性欲,可勃起的功能,和精子发生是必要的。雌激素受体,以及 aromatase,把睾丸激素变换成雌激素的酶,充满大脑,阴茎,和睾丸,为性功能重要的机关。在大脑, estradiol 合成在与性唤起有关的区域被增加。在阴茎,另外,雌激素受体在神经与血管的捆附近与高集中在整个阴茎海绵体被发现。低睾丸激素和提高的雌激素独立于对方增加可勃起的机能障碍的发生。在睾丸,精子发生被雌激素在每水平调制,以 hypothalamus-pituitary-gonadal 轴开始,由 Leydig, Sertoli,和细菌房间列在后面,并且与 ductal 上皮, epididymis,和成熟精子完成。由 estradiol 的阴囊的房间的规定显示出两个一禁止并且 stimulatory 影响,显示剂量依赖者并且时间地的一曲复杂交响乐敏感调整。我们在这评论的目标是阐明到由看荷尔蒙的男性功能的 estradiol 的全面贡献在可勃起的功能,精子发生,和性欲上完成。 | Michael Schulster Aaron M Bernie Ranjith Ramasamy | 2016 | Asian Journal of Andrology2016，18，3： | 17 |
| 2 | Genetically modified mouse models for the study of nonalcoholic fatty liver disease显示文摘Nonalcoholic fatty liver disease(NAFLD) is associated with obesity,insulin resistance,and type 2 diabetes.NAFLD represents a large spectrum of diseases ranging from(1) fatty liver(hepatic steatosis);(2) steatosis with inflammation and necrosis;to(3) cirrhosis.The animal models to study NAFLD/nonalcoholic steatohepatitis(NASH) are extremely useful,as there are still many events to be elucidated in the pathology of NASH.The study of the established animal models has provided many clues in the pathogenesis of steatosis and steatohepatitis,but these remain incompletely understood.The different mouse models can be classified in two large groups.The first one includes genetically modified(transgenic or knockout) mice that spontaneously develop liver disease,and the second one includes mice that acquire the disease after dietary or pharmacological manipulation.Although the molecular mechanism leading to the development of hepatic steatosis in the pathogenesis of NAFLD is complex,genetically modified animal models may be a key for the treatment of NAFLD.Ideal animal models for NASH should closely resemble the pathological characteristics observed in humans.To date,no single animal model has encompassed the full spectrum of human disease progression,but they can imitate particular characteristics of human disease.Therefore,it is important that the researchers choose the appropriate animal model.This review discusses various genetically modified animal models developed and used in research on NAFLD. | Perumal Nagarajan M Jerald Mahesh Kuma Ramasamy Venkatesan Subeer S Majundar Ramesh C Juyal M Jerald Mahesh Kuma | 2012 | World Journal of Gastroenterology2012，18，11： | 7 |
| 3 | 性腺功能减退患者的生育能力保护:研究进展显示文摘越来越多的年轻人和中年人有治疗性腺功能减退症(雄激素含量缺乏相关症状)的需求,其症状包括抑郁症,性冷淡,勃起功能障碍,疲劳。然而,睾酮补充疗法(包括使用天然和合成的类固醇)引起的睾丸功能衰退的患者人数正在增加,特别是那些年轻的运动员,外源性类固醇的使用对这些人的睾丸功能产生了消极影响。外源性睾酮治疗可以影响下丘脑垂体性腺轴的自然调节,造成生精功能受损,可能会导致严重后果,例如无精子症等男性不育症。对于那些患有性腺功能减退症的育龄男性,选择治疗方法时,保护生育能力很重要。研究显示,人绒毛膜促性腺激素(HCG)不仅可以治疗那些睾酮补充疗法引起的无精子症,还有助于维持升高的睾丸内睾酮水平。此外,选择性雌激素受体调节剂常与人绒毛膜促性腺激素联合使用治疗性腺功能减退症,该疗法不仅可以提高总睾酮水平,还有助于保护这些患者的生精功能。 | Ranjith Ramasamy Joseph M Armstrong Larry I Lipshultz | 2015 | Asian Journal of Andrology2015，17，2： | 4 |
| 4 | Microsurgical epididymal sperm aspiration: indications, techniques and outcomes显示文摘Microsurgical epididymal 精子渴望(方山) 从被选择并且取样了使用一台操作显微镜提供的高力量的光放大的 epididymis 的最佳的区域指包含精子的液体的检索。检索精子随后被使用让 intracytoplasmic 精子注射(ICSI ) 导致授精和怀孕。方山被是为在有给它复杂并发症的优秀精子,优秀报导授精和怀孕率,和低风险的高收益的妨碍的精子缺乏的人的精子检索的标准答案技术的许多专家考虑。然而,方山必须在一个操作房间里被执行,要求 microsurgical 技巧并且为用 ICSI 的复制仅仅是有用的。此处我们在场为方山,过程的技术表演和被报导了的结果的候选人病人的评估的概述。 | Aaron M Bernie Ranjith Ramasamy Doron S Stember Peter J Stahl | 2013 | Asian Journal of Andrology2013，15，1： | 4 |
| 5 | Fourier Transform Raman Approach to Structural Correlation in Hemoglobin Derivatives 显示文摘 | VENKATESH B RAMASAMY S MYLRAJAN M | 1999 | Spectrochimica Acta Part A: Molecular Spectroscopy1999，55，： | 1 |
| 6 | Comparison of complications of laparoscopic versus laparoendoscopic single site donor nephrectomy using the modified clavien grading system 显示文摘 | Ramasamy R Afaneh C Katz M | 2011 | J Uml2011，186，4： | 1 |
| 7 | Postcataract endophthalmitis in South India incidence and outcome 显示文摘 | LALITHA P RAJAGOPALAN J PRAKASH K RAMASAMY K PRAJNA NV SRINIVASAN M | 2005 | Ophthalmology2005，112，11： | 1 |
| 8 | Indirubin potentiates ciprofloxacin activity in the Nora efflux pump of Staphylococcusaureus显示文摘 | PONNUSAMY K RAMASAMY M SAVARIMUTHU I | 2010 | Scand J Infect Dis2010，42，67： | 1 |
| 9 | FDI and Pollu- tion: A Granger Causality Test Using Panel Data 显示文摘 | Hoffmann R Ramasamy B Yeung M | 2005 | Journal of International Development2005，17，3： | 1 |
| 10 | Expression of markers for both neuronal and glial cells in human amniotic epithelial cells显示文摘 | Ramasamy T Masashi M | 1996 | Neurosci Lett1996，209，1： | 1 |
| 11 | Role of light andheavy minerals on natural radioactivity level of high background radi-ation area, Kerala, India显示文摘 | Ramasamy V Sundarrajan M Suresh G | 2014 | Appl Radiat Isot2014，85，： | 1 |
| 12 | Expression analysis of turkey (Meleagris gallopavo) toll- like receptors and molecular characterization of avian specific TLR15 显示文摘 | Ramasamy K T Reddy M R Verma P C etal | 2012 | Mol Biol Rep2012，39，： | 1 |
| 13 | Learning the lessons from conflict:pre-hospital cervical spine stabilization following ballistic neck trauma显示文摘 | Ramasamy A Midwinter M Mahoney P | 2009 | Injury2009，12，40： | 1 |
| 14 | China' s outward foreign direct investment: Location choice and firm ownership 显示文摘 | Ramasamy B Yeung M Laforet S | 2012 | Journal of World Business2012，47，1： | 1 |
| 15 | Ab initio and DFT investigations of the mechanistic pathway of singlet bromocarbenes insertion into C-H bonds of methane and ethane显示文摘 | RAMALINGAM M RAMASAMI K VENUVANALINGAM P | 2007 | Lecture Notes in Computer Science2007，4488，2： | 1 |
| 16 | Impact of initial biofilm growth on the anode impedance of microbial fuel cells 显示文摘 | RAMASAMY R P MENCH M M REGAN J M | 2008 | Biotechnol Bioeng2008，101，1： | 1 |
| 17 | China' s Outward Foreign Direct Investment: Location Choice and Firm Ownership 显示文摘 | Ramasamy B Yeung M Laforet S | 2012 | Journal of World Business2012，47，1： | 1 |
| 18 | Receptor for AGE (RAGE) : signaling mechanisms in the pathogenesis of diabetes and its complications 显示文摘 | Ramasamy R Yah S F Schmidt A M | 2011 | Ann N Y Acad Sci2011，1243，： | 1 |
| 19 | Structural Studies on Synthesised Gallium Nitride显示文摘 | Senthil Kumar M Ramasamy P Kumar J | 2000 | Journal of Crystal Growth2000，221，： | 1 |
| 20 | Transconjunctival 20-gauge vitrectomy outcomes 显示文摘 | Shah M Kapur R Raja S Blair MP Park JC Ramasamy B etal | 2011 | Ophthal-mic Surg Lasers Imaging2011，42，4： | 1 |
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