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| 1 | 西藏纳木错深水湖芯反映的8·4ka以来气候环境变化显示文摘利用地震剖面仪和回声测深仪调查了纳木错大部分湖区的水深和沉积物厚度分布,并在湖区东部水深60m的湖盆利用PISTON采样器获得一个332cm长的钻孔。对该钻孔进行了12个AMS14C年代测定,并进行了日历年龄校正和“碳库”效应估算,根据沉积物平均粒径建立了整个钻孔的深度-年代模式。对该钻孔进行了有机碳、总氮、正构烷烃、粒度、元素地球化学、碳酸钙和矿物等环境指标的分析,结果显示8·4ka以来湖区环境变化可以分为明显的3个阶段。早期约8400~6400aB·P.,以温度缓慢下降为主,但在8100~7800aB·P.出现一次显著的冷干事件;中期为6400~2900aB·P.,其开始显示了温暖湿润的环境特点,在6000aB·P.左右出现最强的暖湿特征后其后期转向冷干,在3000~2900aB·P.达到寒冷和干旱的低谷,反映了新冰期时期的温度强烈下降和降水的分配不均;晚期从2900aB·P.到现在,尽管温度出现回升,但总体上显示了向冷干波动变化的趋势,期间第一次降温在1800~1600aB·P.,之后温度回升后在600~300aB·P.再次下降,前者反映了公元初期的降温,后者则是小冰期的反映。 | 朱立平 王君波 林晓 鞠建廷 谢曼平 李明慧 吴艳红 G.Daut R.Musbacher A.Schwalb | 2007 | 第四纪研究2007，27，4： | 69 |
| 2 | Effect of wall rougheners on cross-sectional flow characteristics for non-spherical particles in a horizontal rotating cylinder显示文摘Discrete-element-method(DEM) simulations have been performed to investigate the cross-sectional flow of non-spherical particles in horizontal rotating cylinders with and without wall rougheners. The nonspherical particles were modeled using the three-dimensional super-quadric equation. The influence of wall rougheners on flow behavior of grains was studied for increasing particle blockiness. Moreover,for approximately cubic particles(squareness parameters [555]), the rotational speed, gravitational acceleration and particle size were altered to investigate the effect of wall rougheners under a range of operating conditions. For spherical and near-spherical particles(approximately up to the squareness parameters [344]), wall rougheners are necessary to prevent slippage of the bed against the cylinder wall. For highly cubic particle geometries(squareness parameters larger than [344]), wall rougheners resulted in a counter-intuitive decrease in the angle of repose of the bed. In addition, wall rougheners employed in this study were demonstrated to have a higher impact on bed dynamics at higher rotational speeds and lower gravitational accelerations. Nevertheless, using wall rougheners had a comparatively small influence on particle-flow characteristics for a bed composed of finer grains. | Guang Lu James R.Third Christoph R.Müller | 2014 | Particuology2014，12，1： | 7 |
| 3 | Validation of a discrete element model using magnetic resonance measurements显示文摘The discrete element model(DEM)is a very promising modelling strategy for two-phase granular systems.However,owing to a lack of experimental measurements,validation of numerical simulations of two-phase granular systems is still an important issue.In this study,a small two-dimensional gas- fluidized bed was simulated using a discrete element model.The dimensions of the simulated bed were 44 mm×10 mm×120 mm and the fluidized particles had a diameter dp=1.2 mm and density p=1000 kg/m3.The comparison between DEM simulations and experiments are performed on the basis of time-averaged voidage maps.The drag-law of Beetstra et al.[Beetstra,R.,van der Hoef,M.A.,&Kuipers,J. A.M.(2007b).Drag force of intermediate Reynolds number flow past mono-and bidispersed arrays of spheres. AIChE Journal,53,489–501]seems to give the best results.The simulations are fairly insensitive to the coefficient of restitution and the coefficient of friction as long as some route of energy dissipation during particle–particle and particle–wall contact is provided.Changing the boundary condition of the gas phase at the side-walls from zero-slip to full-slip does not affect the simulation results.Care is to be taken that the cell sizes are chosen so that a reasonable number of particles can be found in a fluid cell. | Christoph R.Müller Stuart A.Scott Daniel J.Holland Belinda C.Clarke Andrew J.Sederman John S.Dennis Lynn F.Gladden | 2009 | Particuology2009，7，4： | 7 |
| 4 | 神经精神药理学治疗药物监测共识指南:2017版显示文摘治疗药物监测(Therapeutic Drug Monitoring,TDM)通过定量测定和解释血药浓度以优化药物治疗。TDM着眼于药代动力学的个体差异,使个体化药物治疗成为可能。在精神病学和神经病学领域中,有可能明显获益于TDM的主要患者群体包括少年儿童、孕妇、老年患者、智障患者、药物滥用者、涉法精神病患者、已知或怀疑药代动力学异常的患者以及合并躯体疾病影响药代动力学的患者。常规剂量下治疗无效,用药依从性难以判断,药物耐受性不佳,以及可能存在药代动力学方面的药物-药物相互作用等情况都是治疗药物监测的典型指征。然而,只有将TDM充分整合到临床治疗过程中,才能发挥其优化药物治疗的潜在优势。为了向临床医生和实验室提供有效的TDM信息,神经精神药理学与药物精神病学协会(Arbeitsgemeinschaft für Neuropsychopharmakologie und Pharmakopsychiatrie,AGNP)的TDM专家组在2004年发表了第一版《精神科治疗药物监测指南》。2011年进行了更新之后,现在再次更新。遵循新版指南,可能会改善神经精神药物治疗的效果,加快很多患者的康复,并降低医疗费用。 | C.Hiemke N.Bergemann H.W.Clement A.Conca J.Deckert K.Domschke G.Eckermann K.Egberts M.Gerlach C.Greiner G.Gründer E.Haen U.Havemann-Reinecke G.Hefner R.Helmer G.Janssen E.Jaquenoud G.Laux T.Messer R.M ssner M.J.Müller M.Paulzen B.Pfuhlmann P.Riederer A.Saria B.Schoppek G.Schoretsanitis M.Schwarz M.Silva Gracia B.Stegmann W.Steimer J.C.Stingl M.Uhr S.Ulrich S.Unterecker R.Waschgler G.Zernig G.Zurek P.Baumann 李文标(主译) 果伟(译) 贺静(译) 鲍爽(译) 路钊(译) 牛梦溪(译) 阮灿军(译) 臧彦楠(译) 王勇(译) 张玲(译) 刘辰庚(译) 李洁(译) 汤宜朗(审校) 王传跃(审校) 王刚(审校) | 2022 | 实用药物与临床2022，25，1： | 6 |
| 5 | Geological controls on coalbed methane reservoir capacity and gas content显示文摘 | R.M Bustin C.R Clarkson | 1998 | International Journal of Coal Geology1998，，1： | 6 |
| 6 | An Approach to Polynomial NARX/NARMAX Systems Identification in a Closed-loop with Variable Structure Control显示文摘Many physical processes have nonlinear behavior which can be well represented by a polynomial NARX or NARMAX model.The identification of such models has been widely explored in literature.The majority of these approaches are for the open-loop identification.However,for reasons such as safety and production restrictions,open-loop identification cannot always be done.In such cases,closed-loop identification is necessary.This paper presents a two-step approach to closed-loop identification of the polynomial NARX/NARMAX systems with variable structure control(VSC).First,a genetic algorithm(GA) is used to maximize the similarity of VSC signal to white noise by tuning the switching function parameters.Second,the system is simulated again and its parameters are estimated by an algorithm of the least square(LS) family.Finally,simulation examples are given to show the validity of the proposed approach. | O.M.Mohamed Vall R.M'hiri | 2008 | International Journal of Automation and computing2008，5，3： | 6 |
| 7 | 神经精神药理学治疗药物监测共识指南:2017版显示文摘2.2剂量相关参考浓度范围对于TDM结果的解释,除了治疗参考浓度范围外还有另一个浓度范围,即所谓的剂量相关参考浓度范围。治疗参考浓度范围的应用是药效动力学问题,而剂量相关参考浓度范围的运用是药代动力学问题。后者比较的是测得的药物浓度与理论预期药物浓度范围。参照药代动力学研究,优先考虑没有合并用药或药物基因组异常的患者群(“正常”患者),在日维持剂量(Daily maintenance dose,D m)、给药间隔(Dosing interval,d i)、总清除率(Total clearance,CL)和生物利用度(Bioavailability,F)已知情况下,某种药物在某个“正常”患者体内的预期平均稳态浓度(Average steady-state concentration,C av)可通过下面的公式计算。 | C.Hiemke N.Bergemann H.W.Clement A.Conca J.Deckert K.Domschke G.Eckermann K.Egberts M.Gerlach C.Greiner G.Gründer E.Haen U.Havemann-Reinecke G.Hefner R.Helmer G.Janssen E.Jaquenoud G.Laux T.Messer R.M ssner M.JMüller M.Paulzen B.Pfuhlmann P.Riederer A.Saria B.Schoppek G.Schoretsanitis M.Schwarz M.Silva Gracia B.Stegmann W.Steimer J.C.Stingl M.Uhr S.Ulrich S.Unterecker R.Waschgler G.Zernig G.Zurek P.Baumann 李文标(译) 果伟(译) 贺静(译) 鲍爽(译) 路钊(译) 牛梦溪(译) 阮灿军(译) 臧彦楠(译) 王勇(译) 张玲(译) 刘辰庚(译) 李洁(译) 汤宜朗(译) 王传跃(译) 王刚(译) | 2022 | 实用药物与临床2022，25，2： | 4 |
| 8 | Climate change,thermal niches,extinction risk and maternal-effect rescue of toad-headed lizards,Phrynocephalus,in thermal extremes of the Arabian Peninsula to the Qinghai-Tibetan Plateau显示文摘Determining the susceptibility of species to changing thermal niches is a major goal for biologists.In this paper we develop an eco-physiological model of extinction risk under climate change premised on behavioral thermoregulation.Our method downscales operative environmental temperatures,which restrict hours of activity of lizards,hr,for present-day climate(1975)and future climate scenarios(2070).We apply our model using occurrence records of 20 Phrynocephalus lizards(or taxa in species complexes)drawn from literature and museum records.Our analysis is phylogenetically informed,because some clades may be more sensitive to rising temperatures.The limits for computed hr predict local extirpations among Phrynocephalus lizards at continental scales and delineate upper boundaries of thermal niches as defined by Extreme Value Distributions.Under the 8.5 Representative Concentration Pathway scenario,we predict extirpation of 64%of local populations by 2070 across 20 Phrynocephalus species,and 12 are at high risk of total extinction due to thermal limits being exceeded.In tandem with global strategies of lower CO_(2) emissions,we propose regional strategies for establishing new national parks to protect extinction-prone taxa by preserving high-elevation climate refugia within existing sites of species occurrence.We propose that evolved acclimatization–maternal plasticity–may ameliorate risk,but is poorly studied.Previous studies revealed that adaptive maternal plasticity by thermoregulating gravid females alter progeny thermal preferences by±1℃.We describe plasticity studies for extinction-prone species that could assess whether they might be buffered from climate warming–a self-rescue.We discuss an epigenetic framework for studying such maternal-effect evolution. | Barry SINERVO Donald B.MILES Yayong WU Fausto R.MÉNDEZ-DE LA CRUZ Sebastian KIRCHHOF Yin QI | 2018 | Integrative Zoology2018，13，4： | 3 |
| 9 | Magnetic resonance studies of a gas-solids fluidised bed:Jet-jet and jet-wall interactions显示文摘Magnetic resonance imaging(MRI)gave images of air jets from orifices in the distributor plate of a bed of poppy seeds.Attention focused on two features:(1)The interaction between nearby vertical jets from two,three or four orifices;(2)Wall effects,where one or more orifices created vertical jets near the vertical wall of the cylinder containing the particle bed.The results show that nearby jets are mutually attracted.Likewise a jet near a wall bends out of the vertical,towards the wall.For multiple adjacent jets,the jet lengths show dependence on orifice layout:the lengths are in reasonable agreement with published measurements,by other methods,for single jets.The MRI gives three-dimensional images of the single jets and of multiple jets,separate or merging. | Meenal Pore Daniel J.Holland Thusara C.Chandrasekera Christoph R.Müller Andrew J.Sederman John S.Dennis Lynn F.Gladden John F.Davidson | 2010 | Particuology2010，8，6： | 2 |
| 10 | Geological controls on coalbed methane reservoir capacity and gas content显示文摘 | R.M Bustin C.R Clarkson | 1998 | International Journal of Coal Geology1998，，1： | 2 |
| 11 | the toxicology of microcystins显示文摘 | R.M Dawson | 1998 | Toxicon1998，，7： | 2 |
| 12 | Budesonide foam versus budesonide enema in active ulcerative proctitis and proctosigmoiditis显示文摘 | V.GROSS S.BAR‐MEIR A.LAVY O.MICKISCH Z.TULASSAY L.PRONAI L.KUPCINSKAS G.KIUDELIS J.POKROTNIEKS á.KOVáCS M.FASZCZYK A.RAZBADAUSKAS B.MARGUS M.STOLTE R.MüLLER R.GREINWALD | 2005 | Alimentary Pharmacology & Therapeutics2005，，2： | 2 |
| 13 | The Teac her Shortage:A Case of Wrong Diagnosis and Wrong Prescription显示文摘 | Ingersoll R.M | | 0，，631： | 1 |
| 14 | Technical Change and the Aggregate Production Function显示文摘 | Solow R.M | | 0，，39： | 1 |
| 15 | Developments in odour control and waste gas treatment biotechnology:A review显示文摘 | Burgess J.E Parsons S.A Stuetz R.M | | 0，，01： | 1 |
| 16 | Self-determination Theory and the Facilitation intrinsic motivation,social development,and well-being显示文摘 | Ryan R.M Deci E.L | | 0，，55： | 1 |
| 17 | The moderator-mediator variable distinction in social psychologieal research:Conceptual,strategic and statistical considerations显示文摘 | Baron R.M Kenny DA | | 0，，06： | 1 |
| 18 | 查看详情显示文摘 | Illa O Garcia C.R Silva C.A Favier I. Picurelli D. Oliva A. Gomez M. Branchadell V. Ortuno R.M | | 0，，： | 1 |
| 19 | One dress,two dress:Dia-lectal influence on spel ing of English words among kindergarten children in Singapore显示文摘 | Dixon L.Q Zhao J Joshi R.M | | 0，，： | 1 |
| 20 | Theoretical improvements in algorithmic efficiency for network flow problems显示文摘 | Edmonds J Karp R.M | | 0，，02： | 1 |
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