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| 1 | 心血管疾病病死率与血清25-羟基维生素D浓度相关性研究显示文摘目的研究心衰死亡、心血管疾病死亡和过早死亡与血清25-羟基维生素D[25(OH)D]浓度的相关性。方法在第3次美国健康和营养调查中,1988~1994年为基线数据,纳入35岁以上参与者13 131名(男性6130名,女性7 001名),随访至2000年12月31日。结果随访8年期间,共有3 266人死亡(24.9%),其中心衰死亡101人,心血管疾病死亡1 451人,早死1 066人。心衰死亡者中有37%血清25(OH)D水平低于20ng/mL,非心衰死亡者为26%(P<0.001)。多元Cox模型显示,血清25(OH)D水平低于20ng/mL的心衰死亡风险是超过30ng/mL的2.06倍(95%CI:1.01~4.25)(P<0.001),过早死亡风险为1.40倍(95%CI:1.17~1.68;P<0.001);血清25(OH)D浓度20~29ng/mL的过早死亡风险是超过30ng/mL的1.11倍(95%CI:0.93~1.33)。结论血清25(OH)D水平不足的成年人死于心血管病、心衰和过早死亡的风险较高。 | 刘隆健 魏敏 陈明 Shelley R Hankins Ana E.Nùez Robert A Watson Perry J Weinstock Craig J.Newschaffer Howard J Eisen 邹强 杨书 陈卫中 | 2013 | 成都医学院学报2013,8,2: | 6 |
| 2 | Hepatitis E virus in patients with acute severe liver injury显示文摘AIM: To examine the incidence of hepatitis E(HepE) in individuals with acute liver injury severe enough to warrant treatment at a transplant unit.METHODS: Hepatitis E virus(HEV) is an emerging pathogen in developed countries causing severe illness, particularly in immunocompromised patients or those with underlying chronic liver disease. HepE infection isoften under diagnosed, as clinicians can be reluctant to test patients who have not travelled to regions traditionally considered hyperendemic for HepE. There are few data regarding the significance of HEV in patients with very severe acute liver injury in developed countries. Eighty patients with acute severe liver injury attending the Scottish Liver Transplant unit were tested for HEV and anti-HEV IgG and IgM. Severe acute liver injury was defined as a sudden deterioration in liver function confirmed by abnormal liver function tests and coagulopathy or presence of hepatic encephalopathy. Eighty percent of these patients were diagnosed with paracetomol overdose. No patients had a history of chronic or decompensated chronic liver disease at time of sampling. IgG positive samples were quantified against the World Health Organization anti-HEV IgG standard. Samples were screened for HEV viral RNA by quantitative reverse transcription polymerase chain reaction.RESULTS: Four cases of hepatitis E were identified. Three of the four cases were only diagnosed on retrospective testing and were initially erroneously ascribed to drug-induced liver injury and decompensated chronic liver disease, with the cause of the decompensation uncertain. One case was caused by HEV genotype 1 in a traveller returning from Asia, the other three were autochthonous and diagnosed on retrospective testing. In two of these cases(where RNA was detected) HEV was found to be genotype 3, the most prevalent genotype in developed countries. Three patients survived, two of whom had been misdiagnosed as having drug induced liver injury. The fourth patient died from sepsis and liver failure precipitated as a result of hepatitis E infection and previously undiagnosed cirrhosis. Histopathology data to date is limited to mainly that seen for endemic HepE. All patients, with the exception of patient 1, demonstrated characteristics of HepE infection, as seen in previously described locally acquired cases.CONCLUSION: In patients with acute severe liver injury, HEV testing should be part of the initial diagnostic investigation algorithm irrespective of suspected initial diagnosis, age or travel history. | Claire Louise Crossan Kenneth J Simpson Darren G Craig Christopher Bellamy Janice Davidson Harry R Dalton Linda Scobie | 2014 | World Journal of Hepatology2014,6,6: | 4 |
| 3 | He and Sr isotopes in the Lau Basin mantle:depleted and primitive mantle components 显示文摘 | Poreda R J Craig H | 1992 | Earth Planet Sci Lett1992,113,: | 2 |
| 4 | Adverse Effects of Low Dose Amiodarone: A Meta-Analysis显示文摘 | Vicken R Vorperian Thomas C Havighurst Stephen Miller Craig T January | 1997 | Journal of the American College of Cardiology1997,,3: | 2 |
| 5 | 抑郁症的非药物治疗:系统性综述与证据图显示文摘背景抑郁症非药物治疗的疗效比较目前仍然不清楚。方法我们对一些系统性综述作了概述,回顾了随机对照试验(RCT),比较抑郁症非药物治疗的有效性和认知行为治疗(CBT)。对多个电子数据库在2016年2月之前发表的所有文献进行了检索,不限制语言。成对的评阅人进行资料纳入、数据提炼并评估偏倚的风险。在适用的时候进行了荟萃分析。结果我们收录了367项RCT,纳入了约2000名患者,进行了11种治疗,导出17项独立的头对头比较。通过标准化的量表评估,发现CBT、自然疗法、行为干预与躯体活动干预可以降低抑郁的严重程度。然而,这些非药物干预的相对疗效仍然缺乏。这些干预对临床缓解和复发的效果不清楚。CBT的发生率比抗抑郁药物更低。局限性由于证据缺乏一致性、证据不清或偏倚风险高,导致证据的质量只是低到中等,限制了我们研究结果的可信度。结论抑郁症的非药物治疗能减少抑郁症状,在轻度到重度抑郁症患者中,应当合并抗抑郁药物治疗,一同进行。对于非药物治疗的选择,应当根据患者的价值观、偏好、临床和社会因素来与患者共同作出决定。 | Wigdan H Farah Mouaz Alsawas Maria Mainou Fares Alahdab Magdoleen H Farah Ahmed T Ahmed Essa A Mohamed Jehad Almasri Michael R Gionfriddo Ana Castaneda-Guarderas Khaled Mohammed Zhen Wang Noor Asi Craig N Sawchuk Mark D Williams Larry J Prokop M Hassan Murad Annie LeBlanc | 2017 | 英国医学杂志中文版2017,20,11: | 2 |
| 6 | A prospective feasibility study of sub-millisievert abdominopelvic CT using iterative reconstruction in Crohn’s disease显示文摘 | Siobhan B O’Neill Patrick D Mc Laughlin Lee Crush Owen J O’Connor Sebastian R Mc Williams Orla Craig Anne Marie Mc Garrigle Fiona O’Neill Jackie Bye Max F. Ryan Fergus Shanahan Michael M Maher | 2013 | European Radiology2013,,: | 2 |
| 7 | Protein folding and its implications for the production of recombinant proteins 显示文摘 | Hlodan R Craig S Pain RH | 1991 | Biotech Genet Eng Rev1991,9,: | 2 |
| 8 | Substructure method in vibration显示文摘 | Craig R R Jr | 1995 | Journal of Mechanical Design1995,,: | 1 |
| 9 | Use of the extended trochantcric os- teotomy in treating prosthetic hip infection 显示文摘 | Brett R Levine MD Craig J | 2009 | J Arthroplasty2009,24,: | 1 |
| 10 | Life-cycle reliability characteristics of minimum structures显示文摘 | R G Bea A Brandtzaeg M J K Craig | 1998 | Journal of Offshore mechanics and Arctic Engineering1998,120,: | 1 |
| 11 | Bacterial vaginosis and HIV,seroprevalencd among female commercial sex workes in ChiangMai,Thailand显示文摘 | Craig R Cohen Ann Drerr Niwar Pruithithada | 1995 | AIDS1995,9,: | 1 |
| 12 | Specificity of class Ⅱ Hsp40 Sisl in maintenance of yeast prion 显示文摘 | Lopez N Aron R Craig EA | 2003 | Molecular Cell2003,14,: | 1 |
| 13 | Vicilin with carbory-terminal KDEL is retained in the endoplasmic reticulum and accumulates to high levels in the leaves of transgenic plants显示文摘 | Wandelt C L Khan M R I Craig S | 1992 | Plant J1992,,2: | 1 |
| 14 | Lymphocyte Responses Following Open and Minimally Invasive Thoracic Surgery显示文摘 | Leaver H A Craig S R Yap P L | 2000 | Eur J Clin Investi2000,30,3: | 1 |
| 15 | Gatlin Ⅲ Growth and body composition of juvenile red drum (Sciaenops ocellatus) fed diets containing lecithinand supplemental choline显示文摘 | Steven R Craig Delbert M | 1997 | Aquaculture1997,151,: | 1 |
| 16 | D- xylose testing:a review显示文摘 | CRAIG R M ATKINSON A J | 1988 | Gastroenterology1988,95,: | 1 |
| 17 | Life-cycle reliability characteristics of minimum structures显示文摘 | Bea R G Brandtzaeg A Craig M J K | 1998 | Journal of Offshore Mechanics and Arctic Engineering1998,120,: | 1 |
| 18 | Rheological and physical differences between foam and emulsion fracturing fluids显示文摘 | Blauer R E Phillips A M Craig D P | 1988 | SPE18214 MS1988,,: | 1 |
| 19 | Invasive Pneumococcal Disease in Children 5 Years After Conjugate Vaccine Introduction - Eight States, 1998-2005显示文摘 | Reingold A Hadler J Farley M M Harrison L Lynfield R Lexau C Bennett N Thomas A Craig A S Smith P J Beall B Whitney C G Moore M Pilishvili T | 2008 | MMWR Morbidity and Mortality Weekly Report2008,,6: | 1 |
| 20 | Theory,instrumentation and applications of magnetoelastic resonance sensors:a review显示文摘 | CRAIG A G SOMNATH C R SANJU R | 2011 | Sensors2011,11,3: | 1 |