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| 1 | Apoptosis of human pancreatic cancer cells induced by Triptolide显示文摘AIM: To investigate apoptosis in human pancreatic cancer cells induced by Triptolide (TL), and the relationship between this apoptosis and expression of caspase-3' bcl-2 and bax. METHODS: Human pancreatic cancer cell line SW1990 was cultured in DMEM media for this study. MTT assay was used to determine the cell growth inhibitory rate in vitro. Flow cytometry and TUNEL assay were used to detect the apoptosis of human pancreatic cancer cells before and after TL treatment. RT-PCR was used to detect the expression of apoptosis-associated gene caspase-3' bcl-2 and bax. RESULTS: TL inhibited the growth of human pancreatic cancer cells in a dose-and time-dependent manner. TL induced human pancreatic cancer cells to undergo apoptosis with typically apoptotic characteristics. TUNEL assay showed that after the treatment of human pancreatic cancer cells with 40 ng/mL TL for 12 h and 24 h, the apoptotic rates of human pancreatic cancer cells increased significantly. RT-PCR demonstrated that caspase-3 and bax were significantly up-regulated in SW1990 cells treated with TL while bcl-2 mRNA was not. CONCLUSION: TL is able to induce the apoptosis in human pancreatic cancer cells. This apoptosis may be mediated by up-regulating the expression of apoptosis- associated caspase-3 and bax gene. | Guo-Xiong Zhou Xiao-Ling Ding Jie-Fei Huang Hong Zhang Sheng-Bao Wu Jian-Ping Cheng Qun Wei | 2008 | World Journal of Gastroenterology2008，14，10： | 22 |
| 2 | Protective effects of MCP-1 inhibitor on a rat model of severe acute pancreatitis显示文摘BACKGROUND:Chemokines and their receptors play key roles in the pathogenesis of acute pancreatitis.This study aimed to establish a rat model of severe acute pancreatitis(SAP) for investigating monocyte chemotactic protein-1(MCP-1) expression in the pathogenesis of the disease.We assessed the effects of the inhibitor of MCP-1,Bindarit,on SAP and explored the mechanisms underlying SAP. METHODS:Seventy-two Sprague-Dawley rats were randomly divided into a saline control group(group S),an SAP group (group P),and a Bindarit group(group T).The SAP model was induced by retrograde infusion of 4%sodium taurocholate into the bilio-pancreatic duct.Based on the SAP model,Bindarit was injected intraperitoneally in group T,and 0.5% methyl cellulose was injected intraperitoneally in groups S and P.In group S,saline was retrogradely infused into the bili- pancreatic duct.Serum amylase levels and the histological changes in the pancreas were assessed at different time- points in each group.Expression of MCP-1 in serum was measured by enzyme-linked immunoadsorbent assay(ELISA). MCP-1 protein and mRNA expression levels were detected by immunohistochemistry,Western blotting,and semi- quantitative reverse transcriptase-polymerase chain reaction (RT-PCR). RESULTS:Serum amylase levels in groups P and T were higher than those in group S.Serum amylase levels were significantly lower in group T than in group P at 6 and 12 hours after operation.The levels of MCP-1 in serum at 6 and 12 hours after operation in group P were significantly higher than in group S,and significantly lower in group T than in group P at 6 and 12 hours after operation.The pathological damage in the pancreas was milder in group T than in group P.MCP-1 protein and mRNA expression levels in the pancreas were higher in groups P and T than in group S.These expression levels were positively correlated with the pathological damage of pancreatic tissues.The activity of MCP-1 in group T was significantly lower than in group P.CONCLUSION:MCP-1 may play important roles in the pathogenesis of SAP.The data suggest that Bindarit ameliorates SAP by inhibiting the activity of MCP-1 in vivo. | Zhou, Guo-Xiong Zhu, Xue-Juan Ding, Xiao-Ling Zhang, Hong Chen, Jian-Ping Qiang, Hui Zhang, Hai-Feng Wei, Qun | 2010 | Hepatobiliary & Pancreatic Diseases International2010，9，2： | 20 |
| 3 | Microbial reduction of uranium(Ⅵ)by Bacillus sp.Dwc-2:A macroscopic and spectroscopic study显示文摘The microbial reduction of U(VI) by Bacillus sp. dwc-2, isolated from soil in Southwest China,was explored using transmission electron microscopy(TEM), X-ray photoelectron spectroscopy(XPS) and X-ray absorption near edge spectroscopy(XANES). Our studies indicated that approximately 16.0% of U(VI) at an initial concentration of 100 mg/L uranium nitrate could be reduced by Bacillus sp. dwc-2 at pH 8.2 under anaerobic conditions at room temperature.Additionally, natural organic matter(NOM) played an important role in enhancing the bioreduction of U(VI) by Bacillus sp. dwc-2. XPS results demonstrated that the uranium presented mixed valence states(U(VI) and U(IV)) after bioreduction, which was subsequently confirmed by XANES. Furthermore, the TEM and high resolution transmission electron microscopy(HRTEM) analysis suggested that the reduced uranium was bioaccumulated mainly within the cell and as a crystalline structure on the cell wall.These observations implied that the reduction of uranium may have a significant effect on its fate in the soil environment in which these bacterial strains occur. | Xiaolong Li Congcong Ding Jiali Liao Liang Du Qun Sun Jijun Yang Yuanyou Yang Dong Zhang Jun Tang Ning Liu | 2017 | Journal of Environmental Sciences2017，29，3： | 8 |
| 4 | Transanal surgery for obstructed defecation syndrome: Literature review and a single-center experience显示文摘Obstructed defecation syndrome(ODS) is a functional disorder commonly encountered by colorectal surgeons and gastroenterologists, and greatly affects the quality of life of patients from both societal and psychological aspects. The underlying anatomical and pathophysiological changes of ODS are complex. However, intra-rectal intussusception and rectocele are frequently found in patients with ODS and both are thought to play an important role in the pathogenesis of ODS. With the development of evaluation methods in anorectal physiology laboratories and radiology studies, a great variety of new operative procedures, especially transanal procedures, have been invented to treat ODS. However, no procedure has been proved to be superior to others at present. Each operation has its own merits and defects. Thus, choosing appropriate transanal surgical procedures for the treatment of ODS remains a challenge for all surgeons. This review provides an introduction of the current problems and options for treatment of ODS and a detailed summary of the essential assessments needed for patient evaluation before carrying out transanal surgery. Besides, an overview of the benefits and problems of current transanal surgical procedures for treatment of ODS is summarized in this review. A report of clinical experience of some transanal surgical techniques used in the authors' center is also presented. | Wei-Cheng Liu Song-Lin Wan SM Yaseen Xiang-Hai Ren Cui-Ping Tian Zhao Ding Ken-Yan Zheng Yun-Hua Wu Cong-Qing Jiang Qun Qian | 2016 | World Journal of Gastroenterology2016，22，35： | 8 |
| 5 | Complementary transmissive ultra-thin meta-deflectors for broadband polarization-independent refractions in the microwave region显示文摘Polarization manipulation is a significant issue for artificial modulation of the electromagnetic(EM) wave, but general mechanisms all suffer the restriction of inherent symmetric properties between opposite handedness.Herein, a strategy to independently and arbitrarily manipulate the EM wave with orthogonal circular polarizations based on a metasurface is proposed, which effectually breaks through traditional symmetrical characteristics between orthogonal handedness. By synthesizing the propagation phase and geometric phase, the appropriate Jones matrix is calculated to obtain independent wavefront manipulation of EM waves with opposite circular polarizations. Two transmissive ultra-thin meta-deflectors are proposed to demonstrate the asymmetrical refraction of transmitted circularly polarized waves in the microwave region. Simulated transmitted phase front and measured far-field intensity distributions are in excellent agreement, indicating that the transmitted wave with different polarizations can be refracted into arbitrary and independent directions within a wide frequency band(relative bandwidth of 25%). The results presented in this paper provide more freedom for the manipulation of EM waves, and motivate the realizations of various polarization-independent properties for all frequency spectra. | YUEYI YUAN KUANG ZHANG XUMIN DING BADREDDINE RATNI SHAH NAWAZ BUROKUR QUN WU | 2019 | Photonics Research2019，7，1： | 5 |
| 6 | Resource allocation in cognitive wireless powered communication networks with wirelessly powered secondary users and primary users显示文摘Dear editor,Wireless powered communication networks(WPCNs)are popular especially for wireless sen-sor networks where sensors can be wirelessly powered.For coordinating wireless power and information transfer,Ju and Zhang in their pioneer work [1] proposed a 'harvest-then-transmit' protocol for WPCN,where the time for wireless power transfer(WPT)and wireless information transfer(WIT)is divided into two phases:the WPT phase and WIT phase. | Ding XU Qun LI | 2019 | Science China(Information Sciences)2019，62，2： | 5 |
| 7 | Principle and performance of BDSBAS and PPP-B2b of BDS-3显示文摘Within the framework of diferential augmentation,this paper introduces the basic technical framework and performance of the BeiDou Global Navigation Satellite System(BDS-3)Satellite-Based Augmentation System(BDSBAS),including orbit products,satellite clock ofset products,ionosphere and its integrity performance.The basic principle of BDS-3 Precise Point Positioning(PPP-B2b)is expounded,the similarities and diferences between the PPP service provided by BDS-3 and International Global Navigation Satellite System(GNSS)Service(IGS)are discussed,and the limitations of PPP-B2b are analyzed.Since both the BDSBAS and PPP-B2b utilize a ground monitoring station network to determine the satellite orbits and clock ofset corrections,and broadcast diferential corrections through the three Geostationary Orbit(GEO)satellites of BDS-3,the feasibility of the co-construction of BDSBAS and PPP-B2b is analyzed,strategies for the infrastructure sharing and correction broadcasting are presented,and the infuences of BDSBAS correction broadcasting strategy adjustment are evaluated.In addition,it assesses the possibility of broadcasting diferential corrections through the Inclined Geosynchronous Orbit(IGSO)satellites of BDS-3,and the feasibility of augmenting satellite navigation with Low Earth Orbit(LEO)satellites. | Yuanxi Yang Qun Ding Weiguang Gao Jinlong Li Yangyin Xu Bijiao Sun | 2022 | Satellite Navigation2022，3，1： | 5 |
| 8 | Bioaccumulation characterization of uranium by a novel Streptomyces sporoverrucosus dwc-3显示文摘The biosorption mechanisms of uranium on an aerobic bacterial strain Streptomyces sporoverrucosus dwc-3,isolated from a potential disposal site for(ultra-)low uraniferous radioactive waste in Southwest China,were evaluated by using transmission electron microscopy(TEM),energy dispersive X-ray(EDX)analysis,Fourier transform infrared spectroscopy(FT-IR),X-ray photoelectron spectroscopy(XPS),proton induced X-ray emission(PIXE)and enhanced proton backscattering spectrometry(EPBS).Approximately60% of total uranium at an initial concentration of 10 mg/L uranium nitrate solution could be absorbed on 100 mg S.sporoverrucosus dwc-3 with an adsorption capacity of more than3.0 mg/g(wet weight)after 12 hr at room temperature at p H 3.0.The dynamic biosorption process of S.sporoverrucosus dwc-3 for uranyl ions was well described by a pseudo second-order model.S.sporoverrucosus dwc-3 could accumulate uranium on cell walls and within the cell,as revealed by SEM and TEM analysis as well as EDX spectra.XPS and FT-IR analysis further suggested that the absorbed uranium was bound to amino,phosphate and carboxyl groups of the cells.Additionally,PIXE and EPBS results confirmed that ion exchange also contributed to the adsorption process of uranium. | Xiaolong Li Congcong Ding Jiali Liao Liang Du Qun Sun Jijun Yang Yuanyou Yang Dong Zhang Jun Tang Ning Liu | 2016 | Journal of Environmental Sciences2016，28，3： | 5 |
| 9 | Preparation,structural characterization of a novel egg-shell palladium sulfide catalyst and its application in selective reductive alkylation reaction显示文摘有核心和钯硫化物的膜被 sulphidizing Pd/C 与 H2S 作为表面准备了的钯金属的新奇卵壳 PdS 催化剂。这催化剂是有效的让 p 氨基的二苯胺(PADPA ) 和 methylisobutyl 酉同类(MIBK ) 的减少的完化负担得起 N-(1,3-dimethylbutyl ) 有直到 99.42% 的变换和到 97.46% 的选择的 -N-phenyl-p-phenylenedianine (DBPPD ) 。与另外的普通的钯硫化物催化剂作比较,表面上的硫化物和钯金属的核心在更低的硫协作在新催化剂的表面上引起 Pd 的钯的膜,它改进它的活动。我们的结果显示这新卵壳 PdS/C 是有效加氢催化剂。 | Qun Feng Zhang Jia Chun Wu Chang Su Feng Feng Qiao Ling Ding Zhao Lian Yuan Hong Wang Lei Ma Chun Shan Lu Xiao Nian Li | 2012 | Chinese Chemical Letters2012，23，10： | 5 |
| 10 | Frequency-modulated continuous waves controlled by space-time-coding metasurface with nonlinearly periodic phases显示文摘The rapid development of space-time-coding metasurfaces(STCMs)offers a new avenue to manipulate spatial electromagnetic beams,waveforms,and frequency spectra simultaneously with high efficiency.To date,most studies are primarily focused on harmonic generations and independent controls of finite-order harmonics and their spatial waves,but the manipulations of continuously temporal waveforms that include much rich frequency spectral components are still limited in both theory and experiment based on STCM.Here,we propose a theoretical framework and method to generate frequency-modulated continuous waves(FMCWs)and control their spatial propagation behaviors simultaneously via a novel STCM with nonlinearly periodic phases.Since the carrier frequency of FMCW changes with time rapidly,we can produce customized time-varying reflection phases at will by the required FMCW under the illumination of a monochromatic wave.More importantly,the propagation directions of the time-varying beams can be controlled by encoding the metasurface with different initial phase gradients.A programmable STCM prototype with a full-phase range is designed and fabricated to realize reprogrammable FMCW functions,and experimental results show good agreement with the theoretical analyses. | Jun Chen Ke Jun Yan Dai Jun Wei Zhang Zhanye Chen Ming Zheng Chen Yunfeng Lu Lei Zhang Li Wang Qun Yan Zhou Long Li Jin Shan Ding Qiang Cheng Tie Jun Cui | 2022 | Light(Science & Applications)2022，11，10： | 4 |
| 11 | A Layout Optimization Method of Composite Wing Structures Based on Carrying Efficiency Criterion显示文摘二水平的布局优化策略为大规模合成翅膀结构在这份报纸被建议。设计要求根据结构的变丑在系统水平被调整,当布局在从系统水平满足限制的分系统水平被优化时。各种各样的失败的来临的度在翅膀面板的批评负担被采用估计结构正在带效率。由作为一个目的优化效率,这个问题的连续性能被保证。使硬的翅膀面板被相等的 orthotropic 盘子建模,并且全球弄弯负担被精力方法预言。stringer 皮肤本地人扣环抵抗上的支持弹性的非线性的效果被神经网络(NN ) 调查并且接近代理人模型。这些失败预言基于分析答案,它能有效地节省计算资源。最后,大规模翅膀结构的不可分的优化作为一个例子被完成。结果完成设计要求并且显示出这个方法的可行性。 | ZHAO Qun DING Yunliang JIN Haibo | 2011 | Chinese Journal of Aeronautics2011，24，4： | 4 |
| 12 | Price-based time and energy allocation in cognitive radio multiple access networks with energy harvesting显示文摘Cognitive radio(CR),a concept that can solve the conflict between spectrum scarcity and low spectrum utilization,has been researched widely recently[1].There are mainly three CR models:interweave,overlay and underlay[1].Among the three CR models,the underlay model is | Ding XU Qun LI | 2017 | Science China(Information Sciences)2017，60，10： | 3 |
| 13 | 次全结肠切除逆蠕动盲直肠吻合对比全结肠切除回直肠吻合治疗顽固性慢传输便秘的外科疗效显示文摘背景:尽管顽固性慢传输便秘(STC)病例数不断增多,但目前鲜有比较不同术式对其治疗效果的报道。本研究旨在比较次全结肠切除逆蠕动盲直肠吻合(SC-ACRA)与全结肠切除回直肠吻合(TC-IRA)的远期手术疗效。方法:回顾性收集2005年1月至2015年1月间在本中心接受TC-IRA(35例)和SC-ACRA(20例)治疗的顽固性STC患者的临床资料。比较两组患者术后功能学结果。结果:两组患者年龄(P=0.655)、性别(P=0.234)、便秘病程(P=0.105)、排便频率(P=0.698)的差异均无统计学意义。中位随访72(12-120)个月,TC-IRA组与SC-ACRA组每日排便次数分别为3(1/6-7)和3(1/6-5)(P=0.578),克利夫兰便秘评分分别为2(0-20)和2(0-19)(P=0.454),克利夫兰失禁评分分别为0(0-5)和0(0-2)(P=0.333),胃肠生活质量指数分别为122(81-132)和120(80-132)(P=0.661)。两组术后并发症发生率的差异亦无统计学意义(37.1%vs 25.0%,P=0.285)。结论:TC-IRA和SC-ACRA均可有效治疗顽固性STC,两种术式远期疗效相当。 | Xiao-Yu Xie Kong-Liang Sun Wen-Hao Chen Yan Zhou Bao-Xiang Chen Zhao Ding Xue-Qiao Yu Yun-Hua Wu Qun Qian Cong-Qing Jiang Wei-Cheng Liu | 2019 | Gastroenterology Report2019，7，6： | 3 |
| 14 | Chirality-assisted lateral momentum transfer for bidirectional enantioselective separation显示文摘Lateral optical forces induced by linearly polarized laser beams have been predicted to deflect dipolar particles with opposite chiralities toward opposite transversal directions.These“chirality-dependent”forces can offer new possibilities for passive all-optical enantioselective sorting of chiral particles,which is essential to the nanoscience and drug industries.However,previous chiral sorting experiments focused on large particles with diameters in the geometrical-optics regime.Here,we demonstrate,for the first time,the robust sorting of Mie(size~wavelength)chiral particles with different handedness at an air–water interface using optical lateral forces induced by a single linearly polarized laser beam.The nontrivial physical interactions underlying these chirality-dependent forces distinctly differ from those predicted for dipolar or geometrical-optics particles.The lateral forces emerge from a complex interplay between the light polarization,lateral momentum enhancement,and out-of-plane light refraction at the particle-water interface.The sign of the lateral force could be reversed by changing the particle size,incident angle,and polarization of the obliquely incident light. | Yuzhi Shi Tongtong Zhu Tianhang Zhang Alfredo Mazzulla Din Ping Tsai Weiqiang Ding Ai Qun Liu Gabriella Cipparrone Juan Jose Saenz Cheng-Wei Qiu | 2020 | Light(Science & Applications)2020，9，1： | 3 |
| 15 | Progress and prospects of horizontal well fracturing technology for shale oil and gas reservoirs显示文摘By systematically summarizing horizontal well fracturing technology abroad for shale oil and gas reservoirs since the “13th Five-Year Plan”, this article elaborates new horizontal well fracturing features in 3D development of stacked shale reservoirs, small well spacing and dense well pattern, horizontal well re-fracturing, fracturing parameters optimization and cost control. In light of requirements on horizontal well fracturing technology in China, we have summarized the technological progress in simulation of multi-fracture propagation, horizontal well frac-design, electric-drive fracturing equipment, soluble tools and low-cost downhole materials and factory-like operation. On this basis, combined with the demand analysis of horizontal well fracturing technology in the “14th Five-Year Plan” for unconventional shale oil and gas, we suggest strengthening the research and development in the following 7 aspects:(1) geology-engineering integration;(2) basic theory and design optimization of fracturing for shale oil and gas reservoirs;(3) development of high-power electric-drive fracturing equipment;(4) fracturing tool and supporting equipment for long horizontal section;(5) horizontal well flexible-sidetracking drilling technology for tapping remaining oil;(6) post-frac workover technology for long horizontal well;(7) intelligent fracturing technology. | LEI Qun XU Yun CAI Bo GUAN Baoshan WANG Xin BI Guoqiang LI Hui LI Shuai DING Bin FU Haifeng TONG Zheng LI Tao ZHANG Haoyu | 2022 | Petroleum Exploration and Development2022，49，1： | 3 |
| 16 | Generation and Realization of Digital Chaotic Key Sequence Based on Double K-L Transform显示文摘 | DU Baoxiang GENG Xiaoli CHEN Fangyue PAN Jing DING Qun | 2013 | Chinese Journal of Electronics2013，22，1： | 2 |
| 17 | Correlation of obstructive sleep apnea hypopnea syndrome with metabolic syndrome in snorers显示文摘Though obstructive sleep apnea hypopnea syndrome(OSAHS) and metabolic syndrome(MS) are correlated;the contributing factors for the occurrence of MS in Chinese snorers remain largely undefined.We aimed to investigate the associated pathogenesis of coexistence of OSAHS and MS in Chinese snorers.A total of 144 Chinese habitual snorers were divided into 3 groups,the control group(simple snorers)(n = 36),the mild OSAHS group(n= 52)and the moderate-to-severe OSAHS group(n = 56).The incidence of MS in the moderate-to-severe OSAHS group(26.8%) was significantly higher than that in the control group(8.3%),the mild OSAHS group(11.1%) and all the OSAHS patients(19.45%)(all P < 0.05).Homeostatic model assessment(HOMA) index and proinsulin(PI) were negatively correlated with nocturnal meanSpO_2 and miniSpO_2.Meanwhile,nocturnal SpO_2 were negatively correlated with body mass index,waist and neck circumferences and diastolic blood pressure,but positively correlated with total cholesterol and high-density lipoprotein cholesterol.The study indicated that in Chinese snorers,moderate-to-severe OSAHS was closely associated with MS via nocturnal hypoxemia. | Qun Zhang Xiaofeng Zhang Mengmeng Zhao Hanpeng Huang Ning Ding Xilong Zhang Hong Wang | 2014 | The Journal of Biomedical Research2014，28，3： | 2 |
| 18 | Research on stateful public key based secure data aggregation model for wireless sensor networks显示文摘Data aggregation technology reduces traffic overhead of wireless sensor network and extends effective working time of the network,yet continued operation of wireless sensor networks increases the probability of aggregation nodes being captured and probability of aggregated data being tampered.Thus it will seriously affect the security performance of the network. For network security issues,a stateful public key based SDAM( secure data aggregation model) is proposed for wireless sensor networks( WSNs),which employs a new stateful public key encryption to provide efficient end-to-end security. Moreover,the security aggregation model will not impose any bound on the aggregation function property,so as to realize the low cost and high security level at the same time. | 秦丹阳 Jia Shuang Yang Songxiang Wang Erfu Ding Qun | 2017 | High Technology Letters2017，23，1： | 2 |
| 19 | An Ant Colony Algorithm Based Congestion Elusion Routing Strategy for Mobile Ad Hoc Networks显示文摘A critical challenge for mobile ad hoc networks is the design of efficient routing protocols which are able to provide high bandwidth utilization and desired fairness in mobile wireless environment without any fixed communication establishments. Although extensive efforts have already been devoted to providing optimization based distributed congestion elusion strategy for efficient bandwidth utilization and fair allocation in both wired and wireless networks,a common assumption therein is the fixed link capacities,which will unfortunately limit the application scope in mobile ad hoc networks where channels keep changing. In this paper,an effective congestion elusion strategy is presented explicitly based on ant colony algorithm for mobile ad hoc networks, which will explore the optimal route between two nodes promptly,meanwhile forecast congestion state of the link. Accordingly,a new path will be found rapidly to have the flow spread around to relieve the congestion degree. Compared with OLSR,the strategy proposed will greatly reduce the packet loss ratio and the average end-to-end delay at the same time,which illustrate that it will make use of networking resource effectively. | Dan-Yang Qin Hong-Wei Li Lin Ma Hong-Bin Ma Qun Ding | 2013 | Journal of Harbin Institute of Technology(New Series)2013，20，3： | 2 |
| 20 | Cooperative resource allocation in cognitive wireless powered communication networks with energy accumulation and deadline requirements显示文摘This study investigates a multi-carrier cognitive wireless powered communication network(CWPCN) with a wirelessly powered primary user(PU). A two-stage cooperative protocol between the PU and the secondary user(SU) is adopted so that the PU can harvest energy from the SU while the SU gains transmission opportunities. It is assumed that the energy harvested by the PU can be accumulated for future usage, and the quality of service of the PU is guaranteed by satisfying the required minimum number of data bits for a given deadline. Herein, we maximize the SU rate by considering the time allocation,subcarrier allocation, and power allocation in both an offline setting(in which the future channel gains are known a priori) and an online setting(in which only the current channel gains are known). In the offline and online schemes, the maximization problem is solved using the block-coordinate descent method and the Lagrange duality method. The effectiveness of the proposed schemes is evaluated and verified via simulation experiments against benchmark schemes. | Ding XU Qun LI | 2019 | Science China(Information Sciences)2019，62，8： | 2 |
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