|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Effect of vehicle weight on natural frequencies of bridges measured from traffic-induced vibration显示文摘Recently, ambient vibration test (AVT) is widely used to estimate dynamic characteristics of large civil structures. Dynamic characteristics can be affected by various environmental factors such as humidity, intensity of wind, and temperature. Besides these environmental conditions, the mass of vehicles may change the measured values when traffic-induced vibration is used as a source of AVT for bridges. The effect of vehicle mass on dynamic characteristics is investigated through traffic-induced vibration tests on three bridges; (1) three-span suspension bridge (128m+404m+128m), (2) five-span continuous steel box girder bridge (59m+3@95m+59m), (3) simply supported plate girder bridge (46m). Acceleration histories of each measurement location under normal traffic are recorded for 30 minutes at field. These recorded histories are divided into individual vibrations and are combined into two groups according to the level of vibration; one by heavy vehicles such as trucks and buses and the other by light vehicles such as passenger cars. Separate processing of the two groups of signals shows that, for the middle and long-span bridges, the difference can be hardly detected, but, for the short span bridges whose mass is relatively small, the measured natural frequencies can change up to 5.4%. | Chul-Young Kim Dae-Sung Jung Nam-Sik Kim Soon-Duck Kwon Maria Q.Feng | 2003 | Earthquake Engineering and Engineering Vibration2003，2，1： | 15 |
| 2 | Effect of Mo on microstructural characteristics and coarsening kinetics of γ' precipitates in Co–Al–W–Ta–Ti alloys显示文摘The solvus temperature,volume fraction,coarsening behavior of Y' precipitates and the partitioning behavior of alloying elements as well as lattice misfit of Y/Y' phases influence the creep behavior of Ni-and Co-base superalloys.However,few investigations about the microstructural characteristics and the coarsening behavior of Y' precipitates were reported in multicomponent novel Co-base superalloys during thermal exposure.Two alloys containing different contents of molybdenum and tungsten have been investigated to explore the effect of molybdenum on Y' solvus temperature,Y + Y' microstructure and Y' coarsening in Co–Al–W–Ta–Ti-base alloys.The results showed that the Y' solvus temperature decreases with the addition of Mo.Mo addition reduces the Y' volume fractions after aging above 1000?C,but results in negligible influence on the Y' volume fractions aging at 900?C.Meanwhile,Y' coarsening is controlled by diffusion in experimental alloys after aging at 900?C and 1000?C,and the kinetics of Y'growth in experimental alloys are consistent with the predictions of LSW theory. | H.J.Zhou F.Xue H.Chang Q.Feng | 2018 | Journal of Materials Science & Technology2018，34，5： | 6 |
| 3 | FGF/FGFR signaling in health and disease显示文摘Growing evidences suggest that the fibroblast growth factor/FGF receptor(FGF/FGFR)signaling has crucial roles in a multitude of processes during embryonic development and adult homeostasis by regulating cellular lineage commitment,differentiation,proliferation,and apoptosis of various types of cells.In this review,we provide a comprehensive overview of the current understanding of FGF signaling and its roles in organ development,injury repair,and the pathophysiology of spectrum of diseases,which is a consequence of FGF signaling dysregulation,including cancers and chronic kidney disease(CKD).In this context,the agonists and antagonists for FGF-FGFRs might have therapeutic benefits in multiple systems. | Yangli Xie Nan Su Jing Yang Qiaoyan Tan Shuo Huang Min Jin Zhenhong Ni Bin Zhang Dali Zhang Fengtao Luo Hangang Chen Xianding Sun Jian Q.Feng Huabing Qi Lin Chen | 2020 | Signal Transduction and Targeted Therapy2020，5，1： | 5 |
| 4 | Targeted Ptpn11 deletion in mice reveals the essential role of SHP2 in osteoblast differentiation and skeletal homeostasis显示文摘The maturation and function of osteoblasts(OBs)rely heavily on the reversible phosphorylation of signaling proteins.To date,most of the work in OBs has focused on phosphorylation by tyrosyl kinases,but little has been revealed about dephosphorylation by protein tyrosine phosphatases(PTPases).SHP2(encoded by PTPN11)is a ubiquitously expressed PTPase.PTPN11 mutations are associated with both bone and cartilage manifestations in patients with Noonan syndrome(NS)and metachondromatosis(MC),although the underlying mechanisms remain elusive.Here,we report that SHP2 deletion in bone gamma-carboxyglutamate protein-expressing(Bglap+)bone cells leads to massive osteopenia in both trabecular and cortical bones due to the failure of bone cell maturation and enhanced osteoclast activity,and its deletion in Bglap+chondrocytes results in the onset of enchondroma and osteochondroma in aged mice with increased tubular bone length.Mechanistically,SHP2 was found to be required for osteoblastic differentiation by promoting RUNX2/OSTERIX signaling and for the suppression of osteoclastogenesis by inhibiting STAT3-mediated RANKL production by osteoblasts and osteocytes.These findings are likely to explain the compromised skeletal system in NS and MC patients and to inform the development of novel therapeutics to combat skeletal disorders. | Lijun Wang Huiliang Yang Jiahui Huang Shaopeng Pei Liyun Wang Jian Q.Feng Dian Jing Hu Zhao Henry M.Kronenberg Douglas C.Moore Wentian Yang | 2021 | Bone Research2021，9，1： | 3 |
| 5 | Modeling the Newtonian dynamics for rotation curve analysis of thin-disk galaxies显示文摘We present an efficient,robust computational method for modeling the Newtonian dynamics for rotation curve analysis of thin-disk galaxies.With appropriate mathematical treatments,the apparent numerical difficulties associated with singularities in computing elliptic integrals are completely removed.Using a boundary element discretization procedure,the governing equations are transformed into a linear algebra matrix equation that can be solved by straightforward Gauss elimination in one step without further iterations.The numerical code implemented according to our algorithm can accurately determine the surface mass density distribution in a disk galaxy from a measured rotation curve(or vice versa).For a disk galaxy with a typical flat rotation curve,our modeling results show that the surface mass density monotonically decreases from the galactic center toward the periphery,according to Newtonian dynamics.In a large portion of the galaxy,the surface mass density follows an approximately exponential law of decay with respect to the galactic radial coordinate.Yet the radial scale length for the surface mass density seems to be generally larger than that of the measured brightness distribution,suggesting an increasing mass-tolight ratio with the radial distance in a disk galaxy.In a nondimensionalized form,our mathematical system contains a dimensionless parameter which we call the'galactic rotation number'that represents the gross ratio of centrifugal force and gravitational force.The value of this galactic rotation number is determined as part of the numerical solution.Through a systematic computational analysis,we have illustrated that the galactic rotation number remains within±10%of 1.70 for a wide variety of rotation curves.This implies that the total mass in a disk galaxy is proportional to V 2 0 Rg,with V0 denoting the characteristic rotation velocity(such as the'flat'value in a typical rotation curve)and Rg the radius of the galactic disk.The predicted total galactic mass of the Milky Way is in good agreement with the star-count data. | James Q.Feng C.F.Gallo | 2011 | Research in Astronomy and Astrophysics2011，11，12： | 1 |
| 6 | Mapping of individual sensory nerve axons from digits to spinal cord with the transparent embedding solvent system显示文摘Achieving uniform optical resolution for a large tissue sample is a major challenge for deep imaging.For conventional tissue clearing methods,loss of resolution and quality in deep regions is inevitable due to limited transparency.Here we describe the Transparent Embedding Solvent System(TESOS)method,which combines tissue clearing,transparent embedding,sectioning and block-face imaging.We used TESOS to acquire volumetric images of uniform resolution for an adult mouse whole-body sample.The TESOS method is highly versatile and can be combined with different microscopy systems to achieve uniformly high resolution.With a light sheet microscope,we imaged the whole body of an adult mouse,including skin,at a uniform 0.8×0.8×3.5μm^(3) voxel resolution within 120 h.With a confocal microscope and a 40×/1.3 numerical aperture objective,we achieved a uniform sub-micron resolution in the whole sample to reveal a complete projection of individual nerve axons within the central or peripheral nervous system.Furthermore,TESOS allowed the first mesoscale connectome mapping of individual sensory neuron axons spanning 5 cm from adult mouse digits to the spinal cord at a uniform sub-micron resolution. | Yating Yi Youqi Li Shiwen Zhang Yi Men Yuhong Wang Dian Jing Jiayi Ding Qingjie Zhu Zexi Chen Xingjun Chen Jun-Liszt Li Yilong Wang Jun Wang Hanchuan Peng Li Zhang Wenjing Luo Jian Q.Feng Yongwen He Woo-Ping Ge Hu Zhao | 2024 | Cell Research2024，34，2： | 0 |
| 7 | EFFECT OF ANNEALING TREATMENT ON THE STRUCTURE OF CdS FILMS显示文摘The effect of annealing treatment on the structure of CdS films was investigated.The cadmium sulfide thin films were prepared by chemical bath deposition, and were annealed at nitrogen atmosphere at different temperatures. The films were characterized by SEM and XPS (X-ray photoelectron spectroscopy). X-ray photoelectron spectroscopy was used to examine the chemical states on the CdS films surface. It was found that thermal annealing could produce large grains of CdS thin films, remove the air contamination and reduce the oxygen content on the CdS films surface. Therefore,the CdS films changed more uniform and smoother surface after thermal annealing. | G.B.Liu W.L.Wang C.G.Hu K.J.Liao Q.Feng L.H.Feng | 2003 | Acta Metallurgica Sinica(English Letters)2003，16，4： | 0 |
| 8 | 树鼩的骨元和骨细胞穴微观结构超微影像的定性比较显示文摘近年来,由于树鼩与灵长类动物的亲缘关系,它们引起了人类发展和疾病研究的兴趣。在这项对树鼩,鼠,狗,狒狒和人类的骨骼超微形态的比较研究中,我们定性分析了骨骼的微观结构和形态,以评估树鼩对人类的亲近程度。在3只成年雄性树鼩 (滇西亚种) (Tupaia belangeri chinensis)的股骨中,使用荧光素异硫氰酸盐样品制备和染色共聚焦成像研究了皮质骨的骨元结构,并使用酸蚀刻SEM观察了骨细胞穴的形态。总体而言,树鼩中骨样形成物的密度和结构以及骨细胞穴的形态更像鼠,与人类,狗和狒狒都明显不同。这些发现表明,尽管树鼩在系统发育上比鼠更接近人类,但它们的骨骼超微形态仍与鼠接近。这是除狗和狒狒之外,第一次对树鼩的骨元和骨细胞穴进行超微影像的研究。这个比较研究的结果丰富了我们对早期灵长类动物骨骼发育,适应性和进化的理解。未来有必要进行进一步的定量比较研究来表征树鼩骨骼的微观形态。 | Vijaya Lakshmi Pavani MOLLI Anubhav JAIN 傅江南 吴英杰 Jian Q.FENG 王谦 | 2020 | 人类学学报2020，39，4： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员