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15篇 您的检索式：作者名="Prokopec"

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		题名	作者	年代	出处	被引量
	1	Marginal zone B cells are naturally reactive to collagen type II and are involved in the initiation of the immune response in collagen-induced arthritis显示文摘Antibodies against type II collagen(CII)are essential for development of collagen-induced arthritis(CIA),but how and where the B-cell response to CII is initiated is not fully known.We show here that naive DBA/1 mice display naturally reactive IgM and IgG anti-CII producing B cells prior to immunization.The CII-reactive B cells were observed in the spleen and recognized as marginal zone(MZ)B cells.After CII immunization,CII-specific B cells expanded rapidly in the spleen,in contrast to the lymph nodes,with the initial response derived from MZ B cells and later by follicular(FO)B cells.This was evident despite that the MZ B cells were subject to stringent tolerance mechanisms by having a greater Fc gamma receptor IIb expression than the FO B cells.Further,the MZ B cells migrated to the FO areas upon immunization,possibly providing antigen and activating FO T cells and subsequently FO B cells.Thus,around CIA onset increased numbers of IgG anti-CII producing FO B cells was seen in the spleen,which was dominated by IgG2a-and IgG2b-positive cells.These data demonstrate that CII-reactive MZ B cells are present before and expand after CII immunization,suggesting an initiating role of MZ B cells in the development of CIA.	Cecilia Carnrot Kajsa E Prokopec Kristina Rasbo Mikael CI Karlsson Sandra Kleinau	2011	Cellular & Molecular Immunology2011，8，4：	3
	2	Adioposity in Czech children followed from 1 month age to adulthood: analysis of individual BMI pattens 显示文摘	Prokopec M Bellisle F	1993	Ann Hum Biol1993，20，：	1
	3	Characterization of advanced cyanate ester/epoxy insulation systems before and after reactor irradiation显示文摘	Prokopec R Humer K Maix R K	2010	Fusion Engineering and Design2010，85，2：	1
	4	TCDD dysregulation of 13 AHR-target genes in rat liver显示文摘	Watson J D Prokopec S D Smith A B	2014	Toxicol Appl Pharmacol2014，274，3：	1
	5	Down regulation of Fc and complement receptors on B cells in rheumatoid arthritis显示文摘	Prokopec KE Rhodiner M Matt P		0，，03：	1
	6	Down regulation of Fc and complement receptors on B cells in rheumatoid arthritis显示文摘	Prokopec KE Rhodiner M Matt P	2010	Clin Immunol2010，137，：	1
	7	Influence of various catalysts on the radiation resistance and the mechanical properties of cyanate ester/epoxy insulation systems显示文摘	R. Prokopec K. Humer R.K. Maix H. Fillunger H.W. Weber	2008	Fusion Engineering and Design2008，，7：	1
	8	Mechanical strength of various cyanate ester/epoxy insulation systems after fast neutron irradiation to the ITER design fluence and beyond显示文摘	R. Prokopec K. Humer R.K. Maix H. Fillunger H.W. Weber	2007	Fusion Engineering and Design2007，，5：	1
	9	Characterization of advanced cyanate ester/epoxy insulation systems before and after reactor irradiation显示文摘	Prokopec R Humer K Maix R K	2010	Fusion Engineering and Design2010，85，2：	1
	10	显示文摘	Prokopec R Humer K Maix R K	2007	Fusion Engineering and Design2007，82，514：	1
	11	Characterization of advanced cyanate ester/epoxy insulation systems before and after reactor irradiation显示文摘	PROKOPEC R HUMER K MAIX R K	2010	Fusion Engineering and Design2010，85，2：	1
	12	Characterization of advanced cyanate ester/epoxy insulation systems before and after reactor irradiation显示文摘	Prokopec R Humer K Maix R K	2010	Fusion Engineering and Design2010，85，2：	1
	13	Influence of various catalysts on the radiation resistance and the mechanical properties of cyanate ester/epoxy insulation systems显示文摘	PROKOPEC R HUMER K MAIX R K et d	2009	Fusion Engineering and Design2009，84，711：	1
	14	Down-regula- tion of Fc and complement receptors on B cells in rheumatoid arthritis 显示文摘	Prokopec KE Rhodiner M Matt P	2010	Clin Immunol2010，137，3：	1
	15	Adiposity in Czech children followed from 1 month of age to adulthood : analysis of individual BMI patterns显示文摘	Prokopec M Bellisle F	1993	Ann Hum Biol1993，20，6：	1

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