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您的检索式：作者名="Priya Mathews"
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| 1 | Genomic change in hepatitis B virus associated with development of hepatocellular carcinoma显示文摘AIM: To determine the genomic changes in hepatitis B virus(HBV) and evaluate their role in the development of hepatocellular carcinoma(HCC) in patients chronically infected with genotype C HBV.METHODS: Two hundred and forty chronic hepatitis B(CHB) patients were subjected and followed for a median of 105 mo. HCC was diagnosed in accordance with AASLD guidelines. The whole X, S, basal core promoter(BCP), and precore regions of HBV were sequenced using the direct sequencing method.RESULTS: All of the subjects were infected with genotype C HBV. Out of 240 CHB patients, 25(10%) had C1653 T and 33(14%) had T1753 V mutation in X region; 157(65%) had A1762T/G1764 A mutations in BCP region, 50(21%) had G1896 A mutation in precore region and 67(28%) had pre-S deletions. HCC occurred in 6 patients(3%). The prevalence of T1753 V mutation was significantly higher in patients who developed HCC than in those without HCC. The cumulative occurrence rates of HCC were 5% and 19% at 10 and 15 years, respectively, in patients with T1753 V mutant, which were significantly higher than 1% and 1% in those with wild type HBV(P < 0.001).CONCLUSION: The presence of T1753 V mutation in HBV X-gene significantly increases the risk of HCC development in patients chronically infected with genotype C HBV. | Danbi Lee Heather Lyu Young-Hwa Chung Jeong A Kim Priya Mathews Elizabeth Jaffee Lei Zheng Eunsil Yu Young Joo Lee Soo Hyung Ryu | 2016 | World Journal of Gastroenterology2016，22，23： | 9 |
| 2 | Endothelial Cell Loss and Central Corneal Thickness in Patients With and Without Diabetes After Manual Small Incision Cataract Surgery显示文摘 | Priya Thomas Mathew Sarada David Nihal Thomas | 2011 | Cornea2011，，4： | 1 |
| 3 | 我和“讨嫌鬼”做搭档显示文摘没有人想坐在利昂旁边,能不坐那儿就不坐那儿。这就是为什么当我踩着铃声冲进美术课教室时,只剩他身边的座位是空的了。普里斯特利女士说:“尼米,请坐下。”我觉得普里斯特利女士不喜欢我。我的美术很差。她说:“今天我们要画一幅幻想的风景画。”利昂举起了手:“我们想画什么就画什么吗矿利昂爱美术课,也爱普里斯特利女士。普里斯特利女士爱美术课,也爱利昂。 | Priya Ann Mathew 祝莉丽 | 2017 | 高中生(作文)2017，0，12： | 0 |
| 4 | 我和“讨嫌鬼”做搭档显示文摘没有人坐在里昂旁边,只要能不坐那儿就不坐那儿。这就是为什么当我踩着铃声冲进美术课教室时,只剩他身边的座位是空的了。普里斯特利夫人说:“尼米,请坐下。”我觉得普里斯特利夫人不喜欢我。我的美术很差。“发挥你的想象力。”她总是这么说。 | Priya Ann Mathew 祝莉丽 | 2017 | 新东方英语(中学版)2017，0，3： | 0 |
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