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| 1 | Molecular biology of high-grade gliomas: what should the clinician know?显示文摘The current World Health Organization classification system of primary brain tumors is solely based on morphologic criteria. However, there is accumulating evidence that tumors with similar histology have distinct molecular signatures that significantly impact treatment response and survival. Recent practice-changing clinical trials have defined a role for routine assessment of O-6-methylguanine-DNA methyltransferase(MGMT) promoter methylation in glioblastoma patients, especially in the elderly, and 1p and 19q codeletions in patients with anaplastic glial tumors. Recently discovered molecular alterations including mutations in IDH-1/2, epidermal growth factor receptor(EGFR), and BRAF also have the potential to become targets for future drug development. This article aims to summarize current knowledge on the molecular biology of high-grade gliomas relevant to daily practice. | Silvia Hofer Elisabeth Rushing Matthias Preusser Christine Marosi | 2014 | Chinese Journal of Cancer2014，33，1： | 7 |
| 2 | Overexpression of cmet is associated with stat3 activation and diminished prognosis in esophageal adenocarcinoma but not in squamous cell carcinoma显示文摘 | Ildiko Mesteri Sebastian F. Schoppmann Matthias Preusser Peter Birner | 2014 | European Journal of Cancer2014，，： | 2 |
| 3 | Brain metastases: pathobiology and emerging targeted therapies显示文摘 | Matthias Preusser David Capper Aysegül Ilhan-Mutlu Anna Sophie Berghoff Peter Birner Rupert Bartsch Christine Marosi Christoph Zielinski Minesh P. Mehta Frank Winkler Wolfgang Wick Andreas Deimling | 2012 | Acta Neuropathologica2012，，2： | 2 |
| 4 | Cardiopulmonary bypass reduction of bronchial blood flow:potential mechanism for lung injury in a neonatal pig model显示文摘 | Schlensak C Doenst T Preusser S l | 2002 | J Thorac Cardiovasc Surg2002，123，6： | 1 |
| 5 | Quartz as a Natural Luminescence Dosimeter显示文摘 | Frank Preusser Makaiko L Chithambo Thomas Gotte | 2009 | Earth- Science Reviews2009，97，1234： | 1 |
| 6 | New developments in the treatment of gastric carcinoma显示文摘 | Wike H Preusser P Fink U | 1990 | Semin Oncol1990，17，1： | 1 |
| 7 | Assessment of BRAF V6OOE mutation status by immunohistochemistry with a mutation-specific monoclonal antibody显示文摘 | Capper D Preusser M Habel A | 2011 | Acta Neuropatho12011，122，1： | 1 |
| 8 | Ki67 index in intracran ia 1 ependymom a: a prom is ing h istopa tho log ical candidate biom arke r 显示文摘 | Preusser M Heinz1 H Gelpi E | 2008 | Histopathology2008，53，1： | 1 |
| 9 | Cardiopulmonary bypass reduction of bronchial blood flow:a potential mechanism for lung injury in a neonatal pig model显示文摘 | Schlensak C Doenst T Preusser S | 2002 | J Thorac Cardiovasc Surg2002，123，6： | 1 |
| 10 | Daylight saving time and moor vehicle crashes:The reduction in pedestrian and vehicle fatalities显示文摘 | Ferguson SA Preusser DF Lund AK et a1 | 1995 | Am J Public Health1995，85，： | 1 |
| 11 | Non-invasive assessment of intratumoral vascularity using arterial spin labeling s a comparison to susceptibility-weighted imaging for the differentiation of primary cerebral lymphoma and glioblastoma显示文摘 | Furtner J Schopf V Preusser M | 2014 | Eur J Radiol2014，83，5： | 1 |
| 12 | New developments in the treatment of gastric carcinoma显示文摘 | Wilke H Preusser P Fink U | 1990 | Semin Oncol1990，17，112： | 1 |
| 13 | Malignant glioma: neuropathology and neurobiology 显示文摘 | Preusser M Haberler C Hainfellner JA | 2006 | Wien Med Wochenschr2006，156，： | 1 |
| 14 | MGMT analysis at DNA,RNA and protein levels inglioblastoma tissue显示文摘 | Preusser M | 2009 | Histol Histopathol2009，24，4： | 1 |
| 15 | Phase Ⅱ study with the combination etopside,doxorubicin,and cisplatin in advanced easurable gastric cancer显示文摘 | Preusser P Wilke H Achterrath W | 1989 | J Clin Oncol1989，7，： | 1 |
| 16 | New developments in the treatment of gastric cancer显示文摘 | Wilke H Preusser P Fink U | 1990 | Semin Oncol1990，17，12： | 1 |
| 17 | High-intensity focused ultrasound : pri-nciples,therapy guidance, simulations and applications显示文摘 | Jenne JW Preusser T Gunther M | 2012 | Z Med Phys2012，22，4： | 1 |
| 18 | Phase Ⅱ study with the combination etoposide,doxorubicin,and cisplatin in advanced measurable gastric cancer显示文摘 | Preusser P Wilke H Achterrath W | 1989 | J Clin Oncol1989，7，： | 1 |
| 19 | Chemotherapy 显示文摘 | Preusser P Achterrrath W Wilke H | 1997 | Gastric Cancer1997，265，： | 1 |
| 20 | Cardiopulmonary bypass reduction of bronchial blood flow:a potential mechanism for lung injury in a neonatal pig model显示文摘 | Schlensak C Doenst T Preusser S | | 0，，06： | 1 |
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