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| 1 | Dendritic cell deficiencies persist seven months after SARS-CoV-2 infection显示文摘Severe Acute Respiratory Syndrome Coronavirus(SARS-CoV)-2 infection induces an exacerbated inflammation driven by innate immunity components.Dendritic cells(DCs)play a key role in the defense against viral infections,for instance plasmacytoid DCs(pDCs),have the capacity to produce vast amounts of interferon-alpha(IFN-α).In COVID-19 there is a deficit in DC numbers and IFN-αproduction,which has been associated with disease severity.In this work,we described that in addition to the DC deficiency,several DC activation and homing markers were altered in acute COVID-19 patients,which were associated with multiple inflammatory markers.Remarkably,previously hospitalized and nonhospitalized patients remained with decreased numbers of CD1c+myeloid DCs and pDCs seven months after SARS-CoV-2 infection.Moreover,the expression of DC markers such as CD86 and CD4 were only restored in previously nonhospitalized patients,while no restoration of integrinβ7 and indoleamine 2,3-dyoxigenase(IDO)levels were observed.These findings contribute to a better understanding of the immunological sequelae of COVID-19. | Alberto Pérez-Gómez Joana Vitallé Carmen Gasca-Capote Alicia Gutierrez-Valencia María Trujillo-Rodriguez Ana Serna-Gallego Esperanza Muñoz-Muela María de los Reyes Jiménez-Leon Mohamed Rafii-El-Idrissi Benhnia Inmaculada Rivas-Jeremias Cesar Sotomayor Cristina Roca-Oporto Nuria Espinosa Carmen Infante-Domínguez Juan Carlos Crespo-Rivas Alberto Fernández-Villar Alexandre Pérez-González Luis Fernando López-Cortés Eva Poveda Ezequiel Ruiz-Mateos JoséMiguel Cisneros Sonsoles Salto-Alejandre Judith Berastegui-Cabrera Pedro Camacho-Martínez Carmen Infante-Domínguez Marta Carretero-Ledesma Juan Carlos Crespo-Rivas Eduardo Márquez JoséManuel Lomas Claudio Bueno Rosario Amaya JoséAntonio Lepe Jerónimo Pachón Elisa Cordero Javier Sánchez-Céspedes Manuela Aguilar-Guisado Almudena Aguilera Clara Aguilera Teresa Aldabo-Pallas Verónica Alfaro-Lara Cristina Amodeo Javier Ampuero María Dolores Avilés Maribel Asensio Bosco Barón-Franco Lydia Barrera-Pulido Rafael Bellido-Alba Máximo Bernabeu-Wittel Candela Caballero-Eraso Macarena Cabrera Enrique Calderón Jesús Carbajal-Guerrero Manuela Cid-Cumplido Yael Corcia-Palomo Juan Delgado Antonio Domínguez-Petit Alejandro Deniz Reginal Dusseck-Brutus Ana Escoresca-Ortega Fátima Espinosa Nuria Espinosa Michelle Espinoza Carmen Ferrándiz-Millón Marta Ferrer Teresa Ferrer Ignacio Gallego-Texeira Rosa Gámez-Mancera Emilio García Horacio García-Delgado Manuel García-Gutiérrez María Luisa Gascón-Castillo Aurora González-Estrada Demetrio González Carmen Gómez-González Rocío González-León Carmen Grande-Cabrerizo Sonia Gutiérrez Carlos Hernández-Quiles Inmaculada Concepción Herrera-Melero Marta Herrero-Romero Luis Jara Carlos Jiménez-Juan Silvia Jiménez-Jorge Mercedes Jiménez-Sánchez Julia Lanseros-Tenllado Carmina López Isabel López Álvaro López-Barrios Luis F.López-Cortés Rafael Luque-Márquez Daniel Macías-García Guillermo Martín-Gutiérrez Luis Martín-Villén JoséMolina Aurora Morillo María Dolores Navarro-Amuedo Dolores Nieto-Martín Francisco Ortega María Paniagua-García Amelia Peña-Rodríguez Esther Pérez Manuel Poyato Julia Praena-Segovia Rafaela Ríos Cristina Roca-Oporto Jesús F.Rodríguez María Jesús Rodríguez-Hernández Santiago Rodríguez-Suárez Ángel Rodríguez-Villodres Nieves Romero-Rodríguez Ricardo Ruiz Zida Ruiz de Azua Celia Salamanca Sonia Sánchez Víctor Manuel Sánchez-Montagut César Sotomayor Alejandro Suárez Benjumea Javier Toral | 2021 | Cellular & Molecular Immunology2021，18，9： | 2 |
| 2 | Characterisati- on of 19 almond cuhivars on the basis of their free amino acids composition显示文摘 | Helena S L Poveda E G Moya M S P | 1998 | Food Chemistry1998，61，4： | 1 |
| 3 | A randomized phase II (RP2) trial of ridaforolimus (R) compared with progestin (P) or chemotherapy (C) in female adult patients with advanced endometrial carcinoma显示文摘 | Oza A M Poveda A Clamp AR | 2011 | J Clin Oncol2011，29，24： | 1 |
| 4 | Synergistic effects of repellents and attractants in potato tuber moth control显示文摘 | Gómez Jiménez M I Poveda K | | 0，，08： | 1 |
| 5 | Isolation of Mycoplasma boris from the respira tory tract of cattle in Bosnia and Herzegovina 显示文摘 | RIFATBEGOVIc M ASSUNCAO P POVEDA J B | 2007 | Vet Rec2007，160，： | 1 |
| 6 | HIV tropism:diagnostictools and implications for disease progression and treatment with entryinhibitors显示文摘 | Poveda E Briz V Quinones-Mateu M | 2006 | Aids2006，20，10： | 1 |
| 7 | Isolation of Myeo- plasma bovis from the respiratory traet of eattle in Bosnia and Herzegovina 显示文摘 | Rifatbegovie M Assuneao P Poveda J B | 2007 | Vet Rec2007，160，： | 1 |
| 8 | Coupling between annual and ENSO timescales in the malaria climate association in Colombia显示文摘 | Poveda G Rojas W Quinones M | 2001 | Environ Health Perspect2001，109，5： | 1 |
| 9 | Free fatty acid composition of regionally-produced Spanish goat cheese and relationship with sensory characteristics 显示文摘 | Poveda J M Cabezas L | 2006 | Food Chemistry2006，95，2： | 1 |
| 10 | Model parametric Hamiltonians and bonding theoretical tools in simulation of catalytic reaction steps:Hydrotreatment of oil components显示文摘 | Poveda M Sierraalta A | 1997 | Journal of Molecular Catalysis A:Chemical1997，119，： | 1 |
| 11 | Metallaey cloheptatrienes of iridium (III) : synthesis and reactivity 显示文摘 | Paneque M Posadas C M Poveda M L | 2007 | Organometallics2007，26，14： | 1 |
| 12 | Low-dose sirolimus combined with angiotensin-converting enzyme inhibitor and statin stabilizes renal function and reduces glomerular proliferation in poor prognosis IgA nephropathy显示文摘 | Cruzado JM Poveda R Ibernon M | 2011 | Nephrol Dial Transplant2011，26，11： | 1 |
| 13 | Peroxynitrite induces gene expression in intervertebral disc c 显示文摘 | Poveda L Hottiger M Boos N | 2009 | Spine2009，34，11： | 1 |
| 14 | Diversification practices: their effect on pest regulation and production显示文摘 | POVEDA K G6MEZ M I MARTNEZ E | 2008 | Re- vista Colombiana de Entomologfa2008，34，2： | 1 |
| 15 | Specific function of phosphoinositide 3-Kinase beta in the control of DNA replication显示文摘 | Marqués M Kumar A Poveda A M | 2009 | Proc Natl Acad Sci U S A2009，106，18： | 1 |
| 16 | Testing Taylor's hypothesis in Amazonian rainfall fields during the WETAMC/LBA experiment显示文摘 | Poveda G Zuluaga M D | 2005 | Advances in Water Resources2005，28，： | 1 |
| 17 | Techno-logical Characterization of Lactobacillus isolates from TraditionalManchego Cheese for Potential use as Adjunct Atarter Cultures显示文摘 | NIETO-ARRIBAS P POVEDA J M SESENA S | 2009 | Food Control2009，20，： | 1 |
| 18 | Familiar Music as an Enhancer of Self-Consciousness in Patients with Alzheimer's Disease显示文摘 | Eva M Arroyo-Anllo Juan Poveda Diaz Roger Gil | 2013 | Biomed Research International2013，2013，75： | 1 |
| 19 | Environmental gradients and population divergence contribute to variation in cuticular wax composition in Juniperus communis显示文摘 | Dodd R S Poveda M M | 2003 | Biochemical Systematics and Ecology2003，31，11： | 1 |
| 20 | Isolation of Mycoplasma boris from the respiratory tract of cattle in Bosnia and Herzegovina 显示文摘 | Rifatbegovic M Assuncao P Poveda J B | 2007 | Vet Rec2007，160，： | 1 |
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