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| 1 | Dendritic cell deficiencies persist seven months after SARS-CoV-2 infection显示文摘Severe Acute Respiratory Syndrome Coronavirus(SARS-CoV)-2 infection induces an exacerbated inflammation driven by innate immunity components.Dendritic cells(DCs)play a key role in the defense against viral infections,for instance plasmacytoid DCs(pDCs),have the capacity to produce vast amounts of interferon-alpha(IFN-α).In COVID-19 there is a deficit in DC numbers and IFN-αproduction,which has been associated with disease severity.In this work,we described that in addition to the DC deficiency,several DC activation and homing markers were altered in acute COVID-19 patients,which were associated with multiple inflammatory markers.Remarkably,previously hospitalized and nonhospitalized patients remained with decreased numbers of CD1c+myeloid DCs and pDCs seven months after SARS-CoV-2 infection.Moreover,the expression of DC markers such as CD86 and CD4 were only restored in previously nonhospitalized patients,while no restoration of integrinβ7 and indoleamine 2,3-dyoxigenase(IDO)levels were observed.These findings contribute to a better understanding of the immunological sequelae of COVID-19. | Alberto Pérez-Gómez Joana Vitallé Carmen Gasca-Capote Alicia Gutierrez-Valencia María Trujillo-Rodriguez Ana Serna-Gallego Esperanza Muñoz-Muela María de los Reyes Jiménez-Leon Mohamed Rafii-El-Idrissi Benhnia Inmaculada Rivas-Jeremias Cesar Sotomayor Cristina Roca-Oporto Nuria Espinosa Carmen Infante-Domínguez Juan Carlos Crespo-Rivas Alberto Fernández-Villar Alexandre Pérez-González Luis Fernando López-Cortés Eva Poveda Ezequiel Ruiz-Mateos JoséMiguel Cisneros Sonsoles Salto-Alejandre Judith Berastegui-Cabrera Pedro Camacho-Martínez Carmen Infante-Domínguez Marta Carretero-Ledesma Juan Carlos Crespo-Rivas Eduardo Márquez JoséManuel Lomas Claudio Bueno Rosario Amaya JoséAntonio Lepe Jerónimo Pachón Elisa Cordero Javier Sánchez-Céspedes Manuela Aguilar-Guisado Almudena Aguilera Clara Aguilera Teresa Aldabo-Pallas Verónica Alfaro-Lara Cristina Amodeo Javier Ampuero María Dolores Avilés Maribel Asensio Bosco Barón-Franco Lydia Barrera-Pulido Rafael Bellido-Alba Máximo Bernabeu-Wittel Candela Caballero-Eraso Macarena Cabrera Enrique Calderón Jesús Carbajal-Guerrero Manuela Cid-Cumplido Yael Corcia-Palomo Juan Delgado Antonio Domínguez-Petit Alejandro Deniz Reginal Dusseck-Brutus Ana Escoresca-Ortega Fátima Espinosa Nuria Espinosa Michelle Espinoza Carmen Ferrándiz-Millón Marta Ferrer Teresa Ferrer Ignacio Gallego-Texeira Rosa Gámez-Mancera Emilio García Horacio García-Delgado Manuel García-Gutiérrez María Luisa Gascón-Castillo Aurora González-Estrada Demetrio González Carmen Gómez-González Rocío González-León Carmen Grande-Cabrerizo Sonia Gutiérrez Carlos Hernández-Quiles Inmaculada Concepción Herrera-Melero Marta Herrero-Romero Luis Jara Carlos Jiménez-Juan Silvia Jiménez-Jorge Mercedes Jiménez-Sánchez Julia Lanseros-Tenllado Carmina López Isabel López Álvaro López-Barrios Luis F.López-Cortés Rafael Luque-Márquez Daniel Macías-García Guillermo Martín-Gutiérrez Luis Martín-Villén JoséMolina Aurora Morillo María Dolores Navarro-Amuedo Dolores Nieto-Martín Francisco Ortega María Paniagua-García Amelia Peña-Rodríguez Esther Pérez Manuel Poyato Julia Praena-Segovia Rafaela Ríos Cristina Roca-Oporto Jesús F.Rodríguez María Jesús Rodríguez-Hernández Santiago Rodríguez-Suárez Ángel Rodríguez-Villodres Nieves Romero-Rodríguez Ricardo Ruiz Zida Ruiz de Azua Celia Salamanca Sonia Sánchez Víctor Manuel Sánchez-Montagut César Sotomayor Alejandro Suárez Benjumea Javier Toral | 2021 | Cellular & Molecular Immunology2021，18，9： | 2 |
| 2 | Treatment of idiopathic membranous nephropathy with the combination of steroids,tacrolimus and mycophenolate mofetil:results of a pilot study显示文摘 | Ballarin J Poveda R Ara J | 2007 | Nephrol Dial Transplant2007，22，11： | 1 |
| 3 | Serological identification of mycoplasmas by growth and metabolic inhibition tests 显示文摘 | Poveda J B Nicholas R | 1998 | Methods Mol Biol1998，104，： | 1 |
| 4 | Rate effect on the mechanical properties of eight types of high strength concrete and comparison with FIB MC2010 显示文摘 | ZHANG X RUIZ G YU R C POVEDA E PORRAS R | 2012 | Construction and Building Materials2012，30，： | 1 |
| 5 | Weight-saving potential of open- and closed-cell functionally graded foams under compressive loading显示文摘 | Poveda R L Gupta N | 2012 | International Journal ofCrashworthiness2012，17，5： | 1 |
| 6 | Treatment of idiopathicmembranous nephropathy with the combination of steroids,tacrolimus and mycophenolate mofetil:results of a pilotstudy显示文摘 | Ballarin J Poveda R Ara J | 2007 | Nephrol Dial Transplant2007，22，11： | 1 |
| 7 | Treatmentguidelines in ovarian cancer 显示文摘 | Poveda V A Casado H A Cervantes R A | 2007 | Clin Transl Oncol2007，9，5： | 1 |
| 8 | In vitro organ culture ofthe bovine intervertebral disc : effects of vertebral endplate andpotential for mechanobiology studies 显示文摘 | Lee C R Iatridis J C Poveda L | 2006 | Spine2006，31，5： | 1 |
| 9 | Circulating tumor cells predict progression free survival and overall survival in patients with relapsed/recurrent advanced ovarian cancer 显示文摘 | Poveda A Kaye SB McCormack R | 2011 | Gynecol Oncol2011，122，3： | 1 |
| 10 | Agerelated responses of vasoactive factors during acute exercise显示文摘 | Poveda J J Berrazueta J R Ochoteco A | 1998 | Horm Metab Res1998，30，11： | 1 |
| 11 | Fenta nyl-trazodone- paracetamol triple drug combination mul timodal analgesia in a mouse model of visceral pain显示文摘 | Ferndndez- DuenasV Poveda R Ferndndez A | 2011 | Phar macol BiochemBehav2011，98，3： | 1 |
| 12 | Treatment of idiopathic membranous nephropathy with the combination of steroids, tacrolimus and mycophenolate mofetil: results of a pilot study显示文摘 | Ballarin J Poveda R Ara J | 2007 | Nephrol Dial Transplant2007，22，11： | 1 |
| 13 | Low-dose sirolimus combined with angiotensin-converting enzyme inhibitor and statin stabilizes renal function and reduces glomerular proliferation in poor prognosis IgA nephropathy显示文摘 | Cruzado JM Poveda R Ibernon M | 2011 | Nephrol Dial Transplant2011，26，11： | 1 |
| 14 | A mean three- dimensional Atlas of the human thalamus: Generation from multiple histological data 显示文摘 | KRAUTH A BLANC R POVEDA A | 2010 | Neuroimage2010，49，3： | 1 |
| 15 | Shear capacity of reinforced high-strength concrete beams 显示文摘 | Ahmad S H Khaloo A R Poveda A | 1986 | ACI Structural Journal1986，83，2： | 1 |
| 16 | Environmental gradients and population divergence contribute to variation in cuticular wax composition in Juniperus communis显示文摘 | Dodd R S Poveda M M | 2003 | Biochemical Systematics and Ecology2003，31，11： | 1 |
| 17 | Circulating tumor cells predict progression free survival and overall survival in patients with relapsed/recurrent advanced ovarian cancer显示文摘 | Poveda A Kaye SB Mccormack R | 2011 | Gynecol Oncol2011，122，3： | 1 |
| 18 | Cochlear filter non- linearity between 500 and 8000 Hz in listeners with normal hear- ing显示文摘 | E A Lopez - Poveda C J Hack R Meddis | 2003 | The Journal of the Acoustical Society of America2003，113，2： | 1 |
| 19 | Average molecular parameters of heavy crude oils and their fractions using NMR spectroscopy 显示文摘 | Poveda J C Molina D R | 2012 | Journal of Petroleum Science and Engineering2012，84，： | 1 |
| 20 | Systemic AA amyloidosis induced by benign neoplasms显示文摘 | Bestard Matamoros 0 Poveda Monje R Ibernon Vilar6 M | 2008 | Nefrolo- gia2008，28，： | 1 |
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