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| 1 | Endoscopic Ultrasound: Accuracy in Staging Superficial Carcinomas of the Esophagus显示文摘 | Sabrina Rampado Paolo Bocus Giorgio Battaglia Alberto Ruol Giuseppe Portale Ermanno Ancona | 2008 | The Annals of Thoracic Surgery2008，，1： | 3 |
| 2 | Combination drug regimens for metastatic clear cell renal cell carcinoma显示文摘Renal cell carcinomas(RCC)make up about 90%of kidney cancers,of which 80%are of the clear cell subtype.About 20%of patients are already metastatic at the time of diagnosis.Initial treatment is often cytoreductive nephrectomy,but systemic therapy is required for advanced RCC.Single agent targeted therapies are moderately toxic and only somewhat effective,leading to development of immunotherapies and combination therapies.This review identifies limitations of monotherapies for metastatic renal cell carcinoma,discusses recent advances in combination therapies,and highlights therapeutic options under development.The goal behind combining various modalities of systemic therapy is to potentiate a synergistic antitumor effect.However,combining targeted therapies may cause increased toxicity.The initial attempts to create therapeutic combinations based on inhibition of the vascular endothelial growth factor or mammalian target of rapamycin pathways were largely unsuccessful in achieving a profile of increased synergy without increased toxicity.To date,five combination therapies have been approved by the U.S.Food and Drug Administration,with the most recently approved therapies being a combination of checkpoint inhibition plus targeted therapy.Several other combination therapies are under development,including some in the phase 3 stage.The new wave of combination therapies for metastatic RCC has the potential to increase response rates and improve survival outcomes while maintaining tolerable side effect profiles. | Viraj V Khetani Daniella E Portal Mansi R Shah Tina Mayer Eric A Singer | 2020 | World Journal of Clinical Oncology2020，11，8： | 2 |
| 3 | Avascular necrosis of the femoral head after femoral neck fracture显示文摘 | Caballer AP Portal L F | 2002 | Clin Orthop2002，39，9： | 1 |
| 4 | Im- munomodulation induced by Avene spring water on Thl- and Th2-dependent cytokine production in healthy subjects and atopic dermatitis patients 显示文摘 | Portales P Aries MF Licu D | 2001 | Skin Pharmacology and Applied Skin Physiology2001，14，4： | 1 |
| 5 | Prevalence of the impaired glu-cose metabolism and its association with risk factors for coronary arterydisease in women with gestational diabetes 显示文摘 | Rivero K Portal VL Vieira M | 2008 | Diabetes Res ClinPract2008，79，43： | 1 |
| 6 | Omeprazole does not reduce gastroesophageal reflux: new insights using multichannel intraluminal impedance technology显示文摘 | Anand P. Tamhankar M.D. Jeffrey H. Peters M.D. Giussepe Portale M.D. Chih-Cheng Hsieh M.D. Jeffrey A. Hagen M.D. Cedric G. Bremner M.D. Tom R. DeMeester M.D | 2004 | Journal of Gastrointestinal Surgery2004，，7： | 1 |
| 7 | Intensity-modulated radiation therapy(IMRT)reduces small bowel,rectum,and bladder doses in patients with cervical cancer receiving pelvic and para-aortic irradiation显示文摘 | Portalance L Chao KS Grigsby PW | 2001 | Int J Radiat Oncol Biol Phys2001，51，1： | 1 |
| 8 | Iron deficiency and anemia in female athletes:causes and risks 显示文摘 | Portal S Epstein M Dubnov G | 2003 | Harefnah2003，142，70： | 1 |
| 9 | Mixed culture solid substrate fermentation of Trichoderma reesei with Aspergillus niger on sugar cane bagasse显示文摘 | Portal L Moreno P | 1999 | Bioresour Technol1999，68，： | 1 |
| 10 | Tunneling显示文摘 | Johnson S La Portal R | 2000 | American Economic Review2000，90，2： | 1 |
| 11 | Mixed culture solid substrate fermentation of Trichoderma reesei with Aspergillus niger on sugar cane bagasse显示文摘 | Gutierrez-Correa M Portal L Moreno P | 1999 | Bioresource Technology1999，68，2： | 1 |
| 12 | Mixed culture solidsubstrate fermentation of Trichoderma reesei with Aspergillusniger on sugar cane bagasse显示文摘 | Gutierrez M Portal L Moreno P | 1999 | Bioresour Technology1999，68，： | 1 |
| 13 | Avascalar necrosis of the femoral head after femoral neck fracture显示文摘 | Bachiller FG Caballer AP Portal LF | 2002 | Clin Orthop2002，，399： | 1 |
| 14 | A vascalar necrosis of the femoral head after femoral neck fracture显示文摘 | Caballer AP Portal LF | 2002 | Clin Orthop2002，，399： | 1 |
| 15 | How to use the C-reactive protein in cardiac disease显示文摘 | Ursella S Manyone M Portale G | 2005 | Minerva Cardioangiol2005，53，1： | 1 |
| 16 | CD4^+ T cell surface CCR5 density as determining factor of virus load in persons infected with human immtmodeficiency virus type 1 显示文摘 | REYNKS J PORTALES P SEGONDY M | 2000 | J Inf Dis2000，181，3： | 1 |
| 17 | Effect of soil structureon the bioavailability of polycyclic aromatic hydrocarbons withinaggregates of a contaminated soil显示文摘 | AMELLAL N PORTAL J M BERTHELIN J | 2001 | Applied Geochemistry2001，16，14： | 1 |
| 18 | A critical revision of the nano-morphology of proton conducting ionomers and polyelectrolytes for fuel cell applications显示文摘 | Kreuer K D Portale G | 2013 | Adv Funct Mater2013，23，43： | 1 |
| 19 | Immunomodulation induced by Avene spring water on Th1-and Th2-dependent cytokine production in healthy subjects and atopic dermatitis patients显示文摘 | Portales P Aries MF Licu D | 2001 | Skin Pharmacol Appl Skin Physiol2001，14，4： | 1 |
| 20 | Continuous veno -venous hemofihration improves hemodynamics in septic shock with acute renal failure without modifying TNFalpha and IL -6 plasma concentrations显示文摘 | Klouche K Cavadore P Portales P | 2002 | J Nephrol2002，15，2： | 1 |
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