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| 1 | Serial imaging of human embryonic stem-cell engraftment and teratoma formation in live mouse models显示文摘表示为基于 radiopharmaceutical 的成像为生物体之发光成像或 HSV1 thymidine kinase (HSV1-TK ) 编码任何一个萤火虫酶(fLuc ) 的记者 transgene 的 lentiviral 向量的二种新类型被构造监视人的胚胎的干细胞(hESC ) 在在移植以后的活老鼠的嫁接和增长。任何一个 transgene 的组成的表示没在文化改变 hESCs 的性质。我们下次在 SCID 鼠标监视了 teratomas 的形成到测试(1 ) 是否修改基因的 hESCs 维持他们的发展 pluripotency,并且(2 ) 是否支撑了记者基因表示,允许 noninvasive,在一个活鼠标模型的 hESC 衍生物的整个身体的成像。我们在接种以后从修改基因的房间以及野类型的 hESCs 2-4 月的两种类型观察了 teratoma 形成。用一个光成像系统,从 fLuc-transduced hESCs 的生物体之发光容易在在摸得出的肿瘤能被检测以前,长忍受 teratomas 的老鼠被检测。开发一个 noninvasive 成像方法对诊所更容易地可译,我们也利用了 HSV1-TK 和它的特定的底层, 1-(2 鈥 ? deoxy-2 鈥 ?fluoro- 尾 - D-arabinofuranosyl )-5-[125I]iodouracil ([125I ] FIAU ) ,记者 / 探查对。在全身的管理以后,[125I ] FIAU 是仅仅由编码 transgene 的 HSV1-TK 酶的 phosphorylated 并且在 transduced 以内保留(并且移植) 房间,由单个光子的排放允许敏感、量的成像计算了断层摄影术。象这些那样的 Noninvasive 成像方法可以使我们能在实时接受者以内重复地监视移植人的干细胞的存在和分发在上一通过记者基因的表达式长期。 | Martin G Pomper Holly Hammond Xiaobing Yu Zhaohui Ye Catherine A Foss Doris D Lin James J Fox Linzhao Cheng | 2009 | Cell Research2009，19，3： | 9 |
| 2 | Repetitive spreading depression-like events result in cell damage in juvenile hippocampal slice cultures maintained in normoxia显示文摘 | Pomper JK Haack S Petzold GC | 2006 | J Neurophysiol2006，95，： | 1 |
| 3 | Increased Plasma and Platelet to Red Blood Cell Ratios Improves Outcome in 466 Massively Transfused Civilian Trauma Patients显示文摘 | John B. Holcomb Charles E. Wade Joel E. Michalek Gary B. Chisholm Lee Ann Zarzabal Martin A. Schreiber Ernest A. Gonzalez Gregory J. Pomper Jeremy G. Perkins Phillip C. Spinella Kari L. Williams Myung S. Park | 2008 | Annals of Surgery2008，，3： | 1 |
| 4 | Chordoid glioma: a neoplasm unique to the hypothalamus and anterior third ventricle 显示文摘 | Pomper MG Passe TJ Burger PC | 2001 | AJNR2001，22，3： | 1 |
| 5 | NAAG peptidase inhibitors and their potential for diagnosis and therapy 显示文摘 | Zhou J Neale JH Pomper MG | 2005 | Nat Rev Drug Discov2005，4，12： | 1 |
| 6 | Management of severe VWD with cryoprecipitate colected by repeated apheresis of a single dedicated donor 显示文摘 | Pomper GJ Rick ME Epstein JS | 2003 | Transfusion2003，43，11： | 1 |
| 7 | Quantification and minimization of magnetic susceptibility artifacts on GRE images显示文摘 | Port J D Pomper M G | 2000 | J Comput Assist Tomogr2000，24，6： | 1 |
| 8 | Development of an intravenously injectable chemically stable aqueous omeprazole for- mulation using nanosuspension technology显示文摘 | Muschwitzer J Achleitner G Pomper H | 2004 | EurJ Pharm Biop- harm2004，58，3： | 1 |
| 9 | Development of an intravenously injectable chemically stable aqueous omeprazole formulation using nanosuspension technology 显示文摘 | MOSCHWITZER J ACHLEITNER G POMPER H | 2004 | Eur J Pharm Biopharm2004，58，3： | 1 |
| 10 | Nosema apis infection in worker and queen Apis mellifera显示文摘 | Webster TC Pomper KW Hunt G | 2004 | Apidologie2004，35，： | 1 |
| 11 | Sensitivities of noninvasive tests for central nervous system vaseulitis:a comparison of lumbar puncture,computed tomography,and magnetic resonance imaging显示文摘 | Stone JH Pomper MG Roubenoff R | 1994 | J Rheumatol1994，21，： | 1 |
| 12 | CNS vasculitis in autoimmune disease:MR imaging findings and correlation with angiography显示文摘 | Pomper MG Miller TJ Stone JH | 1999 | AJNR Am J Neuroradiol1999，20，： | 1 |
| 13 | Development of an intravenously injectable chemically stable aqueous omeprazole formulation using nanosuspension technology 显示文摘 | MSCHWITZER J ACHLEITNER G POMPER H | 2004 | Eur J Pharm Biopharm2004，58，3： | 1 |
| 14 | Molecular imaging: an overview 显示文摘 | Pomper MG | 2001 | Acad Radiol2001，8，： | 1 |
| 15 | Quantification and minimization of magnetic susceptibility artifacts on GRE images显示文摘 | Port JD Pomper MG | 2000 | J Com- put Assist Tomogr2000，24，6： | 1 |
| 16 | Reduction of febrile but not allergic reactions to RBCs and platelets after conversion to universal prestorage leukoreduction显示文摘 | PAGLINO J C POMPER G J FISCH G S | 2004 | Transfusion2004，44，： | 1 |
| 17 | An im- balance between excitatory and inhibitory neurotransmitters in amyotrophic lateral sclerosis revealed by use of 3-T proton mag- netic resonance spectroscopy 显示文摘 | FOERSTER BR POMPER MG CALLAGHAN BC | 2013 | JAMA Neurology2013，70，8： | 1 |
| 18 | Development of an intravenously injectable chemically stable aqueous omeprazole formulation using nanosuspension technology显示文摘 | Moschwitzer J Achleitner G Pomper H | 2004 | Eur J Pharm Biopharm2004，58，4： | 1 |
| 19 | Sensitivities of non-invasive tests for central nervous system vasculitis:A comparison of lumbar puncture,computed tomography and magnetic resonance imaging 显示文摘 | Stone JH Pomper MG Roubenoff R | 1994 | Rheumatol1994，21，： | 1 |
| 20 | Quantification and minimization of magnetic susceptibility artifacts on GRE images显示文摘 | Pomper MG | 2000 | J Comput Assist Tomogr2000，24，6： | 1 |
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