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32篇 您的检索式:作者名="Pinsky M A"
    题名 作者 年代 出处 被引量
1Platelet-rich plasma increases transforming growth factor-beta1 expression at graft-host interface following autologous osteochondral transplantation in a rabbit model显示文摘AIM: To explore the effect of platelet-rich plasma on protein expression patterns of transforming growth factor-beta1(TGF-β1) in cartilage following autologous osteochondral transplantation(AOT) in a rabbit knee cartilage defect model.METHODS: Twelve New Zealand white rabbits received bilateral AOT. In each rabbit, one knee was randomized to receive an autologous platelet rich plasma(PRP) injection and the contralateral knee received saline injection. Rabbits were euthanized at 3, 6 and 12 wk post-operatively. Articular cartilage sections were stained with TGF-β1 antibody. Histological regions of interest(ROI)(left, right and center of the autologous grafts interfaces) were evaluated using Meta Morph. Percentage of chondrocytes positive for TGF-β1 was then assessed.RESULTS: Percentage of chondrocytes positive for TGF-β1 was higher in PRP treated knees for selected ROIs(left; P = 0.03, center; P = 0.05) compared to control and was also higher in the PRP group at each post-operative time point(P = 6.6 × 10^(-4), 3.1 × 10^(-4) and 7.3 × 10^(-3) for 3, 6 and 12 wk, respectively). TGF-β1 expression was higher in chondrocytes of PRP-treated knees(36% ± 29% vs 15% ± 18%)(P = 1.8 × 10^(-6)) overall for each post-operative time point and ROI. CONCLUSION: Articular cartilage of rabbits treated with AOT and PRP exhibit increased TGF-β1 expression compared to those treated with AOT and saline. Our findings suggest that adjunctive PRP may increase TGF-β1 expression, which may play a role in the chondrogenic effect of PRP in vivo.Lorraine A Boakye Keir A Ross John M Pinski Niall A Smyth Amgad M Haleem Charles P Hannon Lisa A Fortier John G Kennedy 2015World Journal of Orthopedics2015,6,11:7
2A Retro- spective Analysis of Immunosuppression Compliance, Dose Reduction and Discontinuation in Kidney Transplant Recipi- ents显示文摘Takemoto S K Pinsky B W Schnitzler M A 2007Am J Transplant2007,7,12:1
3The role of competition effect in the raindrop formation显示文摘Segal Y M Pinsky A K 2007Atmos Res2007,83,:1
4Suppression of cytokine-mediated beta2-integrin activation on circulating neutrophils in critically ill patients显示文摘Rosenbloom A J Pinsky M R Napolitano C 1999J Leukoc Biol1999,66,:1
5Transvisceral lactate fluxes during early endotoxemia 显示文摘Bellomo R Kellum J A Pinsky M R 1996Chest1996,110,1:1
6Introduction to Fourier Analysis and Wavelets显示文摘Pinsky M A 2002Boo/Cole2002,,:1
7Biochemistry of lipoxygenase in relation to food quality显示文摘Eskin N A M Grossman S Pinsky A 1977Crit Rev Food Sci Nutr1977,9,1:1
8Simulation of effects of atmospheric aerosols on deep turbulent convective clouds using a spectral microphysics mixed-phase cumulus cloud model:part- I : model description and possible applications显示文摘KHAIN A POKROVSKY A PINSKY M 2004J Atmos Sci2004,61,24:1
9Compression of semi-solid dendritic Sn-Pb alloys at low strain rates显示文摘PINSKY D A CHARREYRON P FLEMINGS M C 1984Metallurgical Transactions1984,15,1:1
10Effects of hygroscopic seeding on raindrop formation as seen from simulations using a 2000-bin spectral cloud parcel model显示文摘Segal Y Khain A Pinsky M 0,,1:1
11The role of competition effect in the raindrop formation显示文摘Segal Y Pinsky M Khain A 0,,01:1
12Asymptotic Stability and Spiraling Properties for Solutions of Stochastic Equations显示文摘Friedman A Pinsky M 0,,:1
13Is myocardial adrenergic respon- siveness depressed in human septic shock? 显示文摘Cariou A Pinsky MR Monchi M 2008Intensive Care Med2008,34,5:1
14Dynamic effects of positive-pressure ventilation on canine left ventricular pressure-volume relations显示文摘Denault A Y Gorcssan J Pinsky M R 2001J Appl Physiol2001,91,1:1
15The effects of chronic 5-alpha-reductase inhibitor(dutasteride)treatment on rat erectile function显示文摘Pinsky M R Gur S Tracey A J 2011J Sex Med2011,8,11:1
16An epidemic of acute hemorrhagic conjunctivitis in American Samoa caused by coxsackievirus A24variant显示文摘Sawyer L A Hershow R C Pallansch M A Fishbein D B Pinsky P F Broerman S F Grimm B B Anderson L J Hall D B Schonberger L B 1989Am J Epidemiol1989,130,6:1
17Combined observational and model investigations of the Z - LWC 216 relationship in strato- cumulus clouds显示文摘Khain A P Pinsky M Magaritz L 2008J Appl Met & Clim2008,47,:1
18Effects of hygroscopic seeding on raindrop formation as seen from simulations using a 2000-bin spectral cloud parcel model显示文摘Segal Y Khain A Pinsky M et aI 2004Atmos Res2004,71,:1
19Notes on the state-of-the-art mumerical modeling of cloud microphysics 显示文摘Khain A Ovtchinnikov M Pinsky M 2000Atmospheric Research2000,55,3:1
20Notes on the state-of the-art numerical modeling of cloud microphysics显示文摘Khain A Ovtchinnikov M Pinsky M 2000Atmospheric Research2000,55,34:1
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