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| 1 | Embolization of splenorenal shunt associated to portal vein thrombosis and hepatic encephalopathy显示文摘Hepatic encephalopathy(HE)is a cognitive disturbance characterized by neuropsychiatric alterations.It occurs in acute and chronic hepatic disease and also in patients with portosystemic shunts.The presence of these portosystemic shunts allows the passage of nitrogenous substances from the intestines through systemic veins without liver depuration.Therefore,the embolization of these shunts has been performed tocontrol HE manifestations,but the presence of portal vein thrombosis is considered a contraindication.In this presentation we show a cirrhotic patient with severe HE and portal vein thrombosis who was submitted to embolization of a large portosystemic shunt.Case report:a 57 years-old cirrhotic patient who had been hospitalized many times for persistent HE and hepatic coma,even without precipitant factors.She had a wide portosystemic shunt and also portal vein thrombosis.The abdominal angiography confirmed the splenorenal shunt and showed other shunts.The larger shunt was embolized through placement of microcoils,and the patient had no recurrence of overt HE.There was a little increase of esophageal and gastric varices,but no endoscopic treatment was needed.Since portosystemic shunts are frequent causes of recurrent HE in cirrhotic patients,portal vein thrombosis should be considered a relative contraindication to perform a shunt embolization.However,in particular cases with many shunts and severe HE,we found that one of these shunts can be safely embolized and this procedure can be sufficient to obtain a good HE recovery.In conclusion,we reported a case of persistent HE due to a wide portosystemic shunt associated with portal vein thrombosis.As the patient had other shunts,she was successfully treated by embolization of the larger shunt. | Letícia de Campos Franzoni Fábio Cardoso de Carvalho Rafael Gomes de Almeida Garzon Fábio da Silva Yamashiro Laís Augusti Lívia Alves Amaral Santos Mariana de Souza Dorna Júlio Pinheiro Baima Talles Bazeia Lima Carlos Antonio Caramori Giovanni Faria Silva Fernando Gomes Romeiro | 2014 | World Journal of Gastroenterology2014，20，42： | 6 |
| 2 | Fluid and electrolyte overload in critically ill patients: An overview显示文摘Fluids are considered the cornerstone of therapy for many shock states, particularly states that are associated with relative or absolute hypovolemia. Fluids are also commonly used for many other purposes, such as renalprotection from endogenous and exogenous substances, for the safe dilution of medications and as 'maintenance' fluids. However, a large amount of evidence from the last decade has shown that fluids can have deleterious effects on several organ functions, both from excessive amounts of fluids and from their non-physiological electrolyte composition. Additionally, fluid prescription is more common in patients with systemic inflammatory response syndrome whose kidneys may have impaired mechanisms of electrolyte and free water excretion. These processes have been studied as separate entities(hypernatremia, hyperchloremic acidosis and progressive fluid accumulation) leading to worse outcomes in many clinical scenarios, including but not limited to acute kidney injury, worsening respiratory function, higher mortality and higher hospital and intensive care unit lengthof-stays. In this review, we synthesize this evidence and describe this phenomenon as fluid and electrolyte overload with potentially deleterious effects. Finally, we propose a strategy to safely use fluids and thereafter wean patients from fluids, along with other caveats to be considered when dealing with fluids in the intensive care unit. | Bruno Adler Maccagnan Pinheiro Besen André Luiz Nunes Gobatto Lívia Maria Garcia Melro Alexandre Toledo Maciel Marcelo Park | 2015 | World Journal of Critical Care Medicine2015，4，2： | 5 |
| 3 | Immunohistochemical study of the digestive tract of Oligosarcus hepsetus显示文摘AIM: To describe the histology of the digestive tract and to investigate the occurrence of endocrine cells in Oligosarcus hepsetus (O. hepsetus ). METHODS: The digestive tract (DT) of O. hepsetus was divided into esophagus, two stomach regions (glandular and non-glandular) and two intestinal regions (anterior and posterior). These specimens were processed by routine histological techniques and stained with hematoxylin-eosin, Gomori's trichrome, periodic acid Schiff (PAS) and Alcian blue (AB). An immunohistochemical method using avidin-biotin-peroxidase was employed.RESULTS: The esophagus is lined with a non-keratinized stratified squamous epithelium that is reactive to PAS and AB. The stomach has a mucosa lined with a simple columnar epithelium with mucus-secreting cells that are reactive only to PAS. The intestine has a simple columnar epithelium with a brush border and goblet cells that are reactive to PAS and AB. Somatostatin, serotonin and cholecystokinin immunoreactive cells were identified throughout the DT.CONCLUSION: This study revealed adaptations for the species' diet and showed that the distribution and relative frequency of immunoreactive cells are similar to those of other fish. | Danielle A Vieira-Lopes Nadja L Pinheiro Armando Sales Adriana Ventura Francisco G Araújo Iracema D Gomes Aparecida A Nascimento | 2013 | World Journal of Gastroenterology2013，19，12： | 2 |
| 4 | Photochemical responses and oxidative stress in the clones of Coffea canephora under water deficit conditions显示文摘 | Lima A L S DaMatta F M Pinheiro H A | 2002 | Environmental and Experimental Botany2002，47，23： | 1 |
| 5 | Photochemical responses and oxidative stress in two clones of Coffea canephora under water deficit conditions显示文摘 | LIMA A L S DAMATT F M PINHEIRO H A | 2002 | Environmental and Experimental Botany2002，47，： | 1 |
| 6 | Polyketides from the marine sponge Plakortis angulospiculatus 显示文摘 | EpilZanio R Pinheiro L Alves N | 2005 | J Brazil Chem Soc2005，16，： | 1 |
| 7 | Prostatic arterial embolization for benign prostatic hyperplasia:short-and intermediate-term results显示文摘 | Pisco J Campos Pinheiro L Bilhim T | 2013 | Radiology2013，266，： | 1 |
| 8 | Determination of Formaldehyde by Acetaldehyde in Urine by HPLC显示文摘 | Deandrade J B Deandrade M V Pinheiro H L C | 1999 | American Laboratory1999，31，10： | 1 |
| 9 | Embolisation of prostatic arteries as treatment of moderate to severe lower urinary symptoms(LUTS)secondary to benign hyperplasia:results of short-and mid-term follow-up 显示文摘 | Pisco JM Rio Tinto H Campos Pinheiro L | 2013 | Eur Radiol2013，23，： | 1 |
| 10 | Delay of Ripening of 'Pedro Sato' Guava with 1- methyleyclopropene显示文摘 | BASSETTO E JACOMINO A P PINHEIRO A L | 2005 | Postharvest Biology and Technology2005，35，： | 1 |
| 11 | The epitaxial growth of Pd electrodeposition on Au(100) studied by LEED and RHEED 显示文摘 | Pinheiro A L N Zei M S Luo M F | 2006 | Surface Science2006，600，： | 1 |
| 12 | Novel ABCA3 mutations as a cause of respiratory distress in a term newborn显示文摘 | Goncalves JP Pinheiro L Costa M | 2014 | Gene2014，534，： | 1 |
| 13 | Nodal analysis of switched-current filters显示文摘 | DE QUEIROZ A C M PINHEIRO P R M CALDBA L P | 1993 | IEEE Transactions on Circuits And Systems-Ⅱ Analog And Digital Signal Procesing1993，40，1： | 1 |
| 14 | Ovarian follicular dynamic in Nelore breed (Bos indicus) cattle显示文摘 | FIGUEIREDO R A BARROS C M PINHEIRO O L | | 0，，08： | 1 |
| 15 | Heat stress impairs performance and induces intestinal inflammation in broiler chickens infected with Salmonella Enteritidis显示文摘 | Quinteiro Filho W M Gomes A V S Pinheiro M L | 2012 | Avian Pa-thology2012，41，5： | 1 |
| 16 | 限饲和再投喂对不同日龄鸡消化酶促反应的影响显示文摘试验旨在评价限饲和再投喂对两个不同日龄(7和35d)鸡酶活性和胃肠道器官重量的影响,在每种日龄下,鸡被限饲70%(30%自由采食)7d,然后自由采食3d。对照组自由采食10d。对胰腺中糜蛋白酶、胰蛋白酶、淀粉酶、脂肪酶活性和小肠中蔗糖酶、麦芽糖酶的活性进行分析,并且测量了腺胃、肌胃、小肠和大肠的重量。在14d,与对照组相比,限饲组的胰蛋白酶、淀粉酶活性均降低,但在42d,与对照组相比,限饲组蔗糖酶活性降低,表明限饲对酶活性的影响与日龄有关。限饲可以降低完成期(42d)各器官的重量。日龄35~42d的鸡,在再投喂后,器官重量增加,并且达到与对照组一致。在起始期(14d),腺胃和肌胃受限饲的影响很小,在完成期,肌胃也是受影响最小的器官,而小肠时受影响最严重。限饲的所有影响在恢复饲喂3d后被逆转,表明这种改变时快速且可逆的,并且限饲和再投喂与年龄有关。 | Cristiane R A Duarte Maria L M Vicentini P Pinheiro D F | 2014 | 饲料博览2014，0，10： | 1 |
| 17 | Optimization of extraction of high-ester pectin from passion fruit peel (Pasiflora edulits flavicarpa) with citric acid by using response surface methodology显示文摘 | Pinheiro E R Silva I M D A Gonzaga L V | 2008 | Bioresource Tech- nolo2008，99，： | 1 |
| 18 | Failure Trends in a Large Disk Drive Population显示文摘 | PINHEIRO E WEBER W D BARROSO L A | 2007 | Proceedings of the 5th USENIX Conference on File and Storage Technologies (FAST''07)2007，，： | 1 |
| 19 | Leaf gas exchange,chloroplastic pigments and dry matter accumulation in castor bean (Ricinus communis L) seedlings subjected to salt stress conditions显示文摘 | PINHEIRO H A SILVA J V ENDRES L | | 0，，03： | 1 |
| 20 | Optimization of extraction of high-ester pectin from passion fruit peel (Passiflora edulis flavicarpa) with citric acid by using response surface methodology显示文摘 | Pinheiro E Silva I M D A Gonzaga L V | 2008 | Bioresource Technology2008，99，13： | 1 |
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