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| 1 | Emerging concepts in alcoholic hepatitis显示文摘Severe alcoholic hepatitis is implicated as a costly,worldwide public health issue with high morbidity and mortality. The one-month survival for severe alcoholic hepatitis is low with mortality rates high as 30%-50%. Abstinence from alcohol is the recommended firstline treatment. Although corticosteroids remain as the current evidence based option for selected patients with discriminant function > 32, improvement of short-term survival rate may be the only benefit. Identification of individuals with risk factors for the development of severe alcoholic hepatitis may provide insight to the diverse clinical spectrum and prognosis of the disease. The understanding of the complex pathophysiologic processes of alcoholic hepatitis is the key to elucidating new therapeutic treatments. Newer research describes the use of gut microbiota modification, immune modulation, stimulation of liver regeneration, caspase inhibitors, farnesoid X receptors, and the extracorporeal liver assist device to aid in hepatocellular recovery. Liver transplantation can be considered as the last medical option for patients failing conventional medical interventions. Although the preliminary data is promising in patients with low risk of recividism, controversy remains due to organ scarcity. This review article comprehensively summarizes the epidemiology, pathophysiology, risk factors, and prognostic indicators of severe alcoholic hepatitis with a focus on the current and emerging therapeutics. | Phoenix Fung Nikolaos Pyrsopoulos | 2017 | World Journal of Hepatology2017，9，12： | 3 |
| 2 | Therapeutic mefformin/AMPK activation promotes the angiogenic phenotype in the ERal-pha negative MDA-MB-435 breast cancer model显示文摘 | Phoenix KN Vumbaca F Claffey KP | 2009 | Breast Cancer Res Treat2009，113，： | 1 |
| 3 | A comparison of probabilistic technique for the strength of fibrous materials under local load-sharing among fibers显示文摘 | Smith R L Phoenix S L | 1983 | Int J Solids Struc1983，19，： | 1 |
| 4 | Non-local Interatomic Correlations in the m Icromaser 显示文摘 | PHOENIX S J D BARNETT S M | 1993 | J M od Opt1993，40，： | 1 |
| 5 | Impacts of parasitic plants on natural communities 显示文摘 | Press M C Phoenix G K | 2005 | New phytologist2005，166，3： | 1 |
| 6 | A chemical equilibrium equation of state model for elemental sulfur and sulfur-containing fluids显示文摘 | HEIDEMANN R A PHOENIX A V KARAN K | 2001 | Industrial & Engineering Chemistry Research2001，40，9： | 1 |
| 7 | Fluctuations and entropy in models of quantum optical resonance显示文摘 | PHOENIX S J D KNIGHT P L | 1988 | Ann Phys1988，186，12： | 1 |
| 8 | Sounding the death knell for microbes? 显示文摘 | Harris F Dennison SR Phoenix DA | 2014 | Trends Mol Med2014，20，7： | 1 |
| 9 | Periodicity, phase and entropy in models of two-photon resonance显示文摘 | PHOENIX S J D KNIGHT P L | 1990 | J Opt Soc Am(B)1990，7，1： | 1 |
| 10 | The role of tryptophan in fatigue in different condition of stress显示文摘 | Castell L M Yamamoto T Phoenix J | 1999 | Adv Exp Med Biol1999，467，： | 1 |
| 11 | A chemical equilibrium equation of state model for elemental sulfur and sulfur-containing fluids显示文摘 | HEIDEMANN R A PHOENIX A V KARAN K | 2001 | Ind Eng Chem Res2001，40，： | 1 |
| 12 | Characterization of metal-cyanobactefia sorption reactions: a combined macroscopic and infrared spectroscopic investigation 显示文摘 | YEE N BENNING L G PHOENIX V R | 2004 | Environ Sci Technol2004，38，3： | 1 |
| 13 | Impacts of parasitic plants on natural communities 显示文摘 | Press M C Phoenix G K | 2005 | New Phyto2005，166，3： | 1 |
| 14 | Linking physiological traits to impacts on community structure and function:the role of root hemiparasitic Orobanchaceae (ex-Scrophulariaceae)显示文摘 | Phoenix GK Press MC | | 0，，： | 1 |
| 15 | Using sound for mi- crobial eradication- light at the end of the tunnel? 显示文摘 | Harris F Dennison SR Phoenix DA | 2014 | FEMS Microbiol Lett2014，356，1： | 1 |
| 16 | Stochastic strength and fatigue of fiber bundles显示文摘 | Phoenix S L | 1978 | International Journal of Fracture1978，14，3： | 1 |
| 17 | The effects of primers and surface bonding characteristics on the adhesion of polyurethane to two commonly used silicone elastomers 显示文摘 | Chang PP Hansen NA Phoenix RD | 2009 | J Prosthodont2009，18，1： | 1 |
| 18 | Thermo-dynamic equilibrium analysis of ring opening of decalin 显示文摘 | Govindhakannan J Chandra Mouli K Phoenix A | 2012 | Fu-el2012，97，40： | 1 |
| 19 | Establishment of an Entangled Atom-field State in the Jaynes-Cummings Model显示文摘 | | 1991 | Phys Rev A1991，44，9： | 1 |
| 20 | Stress concentrations around muhiple fiber breaks in an elastic matrix with local yielding or debonding using Quadratic Influence Superposition显示文摘 | Beyerlein I J Phoenix S L | 1996 | Journal of the Mechanics and Physics of Solids1996，44，12： | 1 |
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