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| 1 | Slow transit constipation显示文摘 | Bharucha AE Philips SF | | 0，，01： | 1 |
| 2 | AGA technical review of constipation显示文摘 | Locke GR Ⅲ Pemberton JH Philips SF | 2000 | Gastroenterology2000，119，： | 1 |
| 3 | Endoscopic submucosal dissection vs laparoscopic colorectal resection for early colorectal epithelial neoplasia显示文摘AIM: To compare the short term outcome of endoscopic submucosal dissection(ESD) with that of laparoscopic colorectal resection(LC) for the treatment of early colorectal epithelial neoplasms that are not amenable to conventional endoscopic removal. METHODS: This was a retrospective cohort study. The clinical data of all consecutive patients who underwent ESD for endoscopically assessed benign lesions that were larger than 2 cm in diameter from 2009 to 2013 were collected. These patients were compared with a cohort of controls who underwent LC from 2005 to 2013. Lesions that were proven to be malignant by initial endoscopic biopsies were excluded. Mid and lower rectal lesions were not included because total mesorectal excision, which bears a more complicated postoperative course, is not indicated for lesions without histological proof of malignancy. Both ESD and LC were performed by the same surgical unit with a standardized technique. The patients were managed according to a standard protocol, and they were closely monitored for complications after the procedures. All hospital records were reviewed, and the following data were compared between the ESD and LC groups: patient demographics, size and location of the lesions, procedure time, shortterm clinical outcomes and pathology results. RESULTS: From 2005 to 2013, 65 patients who underwent ESD and 55 patients who underwent LC were included in this study. The two groups were similar in terms of sex(P = 0.41) and American Society of Anesthesiologist class(P = 0.58), although patients in the ESD group were slightly older(68.6 ± 9.4 vs 64.6 ± 9.9, P = 0.03). ESD could be accomplished with a shorter procedure time(113 ± 66 min vs 153 ± 43 min, P < 0.01) for lesions of comparable size(3.0 ± 1.2 cm vs 3.4 ± 1.4 cm, P = 0.22) and location(colon/rectum:59/6 vs colon/rectum: 52/3, P = 0.43). ESD appeared to be associated with a lower short-term complication rate, but the difference did not reach statistical significance(10.8% vs 23.6%, P = 0.06). In the LC arm, a total of 22 complications occurred in 13 patients. A total of 7 complications occurred in the ESD arm, including 5 perforations and 2 episodes of bleeding. All perforations were observed during the procedure and were successfully managed by endoscopic clipping without emergency surgical intervention. Patients in the ESD arm had a faster recovery than patients in the LC arm, which included shorter time to resume normal diet(2 d vs 4 d, P = 0.01) and a shorter hospital stay(3 d vs 6 d, P < 0.01). CONCLUSION: ESD showed better short-term clinical outcomes in this study. Further prospective randomized studies will be required to evaluate the efficacy and superiority of colorectal ESD over LC. | Sophie SF Hon Simon SM Ng Tiffany CL Wong Philip WY Chiu Tony WC Mak WW Leung Janet FY Lee | 2015 | World Journal of Gastrointestinal Endoscopy2015，7，17： | 1 |
| 4 | Colonic tone and motility in patients with irritable bowel syndrome显示文摘 | Camilleri M Philips SF | 1992 | Mayo Clin Proc1992，67，： | 1 |
| 5 | Eosinophilic gastroenteri- tis : a clinicopathological study of patients with disease of the mucosa, muscle layer, and snbserosal tissues 显示文摘 | Talley N J Shorter RG Philips SF | 1990 | Gut1990，31，1： | 1 |
| 6 | Onset of efficacy of montelukast in seasonal allergic rhinitis 显示文摘 | Weinstein SF Philip G Hampel FC Jr | 2005 | Allergy Asthma Proc2005，26，1： | 1 |
| 7 | Eosinophilic gastroenteritis : a clinicopathological study of patients with disease of the mucosa,muscle layer,and subserosal tissues显示文摘 | TaUey NJ Shorter RG Philips SF eta/ | 1990 | Gut1990，31，1： | 1 |
| 8 | Montelukast effectively treats the nighttime impact of seasonal allergic rhinitis 显示文摘 | Meltzer EO Philip G Weinstein SF | 2005 | Am JRhinol2005，19，6： | 1 |
| 9 | A clinicopathological study of patients with disease of the mucosa,muscle layer and subserosal tissues显示文摘 | Tally NJ Shorter RG Philips SF Eosinophilic gastroenteritis | 1990 | Gut1990，31，1： | 1 |
| 10 | Eosinophilic gastroenteritis : a clinicopathological study of patients with disease of the mucosa, muscle layer, and subserosal tissues 显示文摘 | Talley N J Shorter RG Philips SF | 1990 | Gut1990，31，1： | 1 |
| 11 | Onset of efficacy of montelukast in seasonal allergic rhinitis显示文摘 | Philip G Hampel FC Jr | 2005 | Allergy Asthma Proc2005，26，1： | 1 |
| 12 | Montelukast effectively treats the nighttime impact of seasonal allergic rhinitis 显示文摘 | Mehzer EO Philip G Weinstein SF | 2005 | Am J Rhinol2005，19，6： | 1 |
| 13 | Eosinophilic gastroenteritis:a clinicopathological study of patients with diseases of the mucosa,muscle layer,and subserosal tissues显示文摘 | Talley NJ Shorter RG Philips SF | 1990 | Gut1990，31，1： | 1 |
| 14 | Eosinophilic gastroenteritis a clinicpathologic study of the patients with disease of the mucosamus- cle Layes and subserosal tissues 显示文摘 | Talley NJ Shorter RG Philips SF | 1990 | Gut1990，31，： | 1 |
| 15 | Longitudinal and radial variations of pressure in the human anal sphincter显示文摘 | Taylor BM Beart JrRW Philips SF | 1984 | Castroenterology1984，86，： | 1 |
| 16 | American gastroenterological association medical position statement: guidelines on constipation显示文摘 | Locke GR Pemberton JH Philips SF | 2000 | Gastroenterology2000，119，6： | 1 |
| 17 | Simplified assessment of segmental colonic transit显示文摘 | Metcalf AM Philips SF Zinsmeister AR | 1987 | Gastroenterology1987，92，1： | 1 |
| 18 | Eosinophilic gastroenteri- tis: a clinicopathological study of patients with disease of the mu- cosa, muscle layer and subserosal tissures显示文摘 | Telley NJ Shorter RG Philips SF | 1990 | Gut1990，31，： | 1 |
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