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13篇 您的检索式：作者名="Philips AC"

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		题名	作者	年代	出处	被引量
	1	Caco-2 cell monolayers as a model for drug transport across the intestinal mucosa显示文摘	Allen RH Robert AC Philip SB	1990	Pharm Res1990，7，9：	1
	2	Changes in human hepatic metabolism in steatosis and cirrhosis显示文摘AIM To understand the underlying metabolic changes in human liver disease we have applied nuclear magnetic resonance(NMR) metabolomics analysis to human liver tissue.METHODS We have carried out pilot study using 1H-NMR to derive metabolomic signatures from human liver from patients with steatosis, nonalcoholic steatohepatitis(NASH) or alcohol-related liver damage(ARLD) to identify species that can predict outcome and discriminate between alcohol and metabolic-induced liver injuries. RESULTS Changes in branched chain amino acid homeostasis, tricarboxylic acid cycle and purine biosynthesis intermediates along with betaine were associated with the development of cirrhosis in both ARLD and nonalcoholic fatty liver disease. Species such as propylene glycol and as yet unidentified moieties that allowed discrimination between NASH and ARLD samples were also detected using our approach.CONCLUSION Our high throughput, non-destructive technique for multiple analyte quantification in human liver specimens has potential for identification of biomarkers with prognostic and diagnostic significance.	Zoe Schofield Michelle AC Reed Philip N Newsome David H Adams Ulrich L Günther Patricia F Lalor	2017	World Journal of Gastroenterology2017，23，15：	1
	3	Association of apolipoprotein E2 allele with diabetic nephropathy in caucasian subjects with DDM显示文摘	Tahseen AC Philip HD Sudesk K	1998	Diabetes1998，47，：	1
	4	Characterization ofa novel mutation in the von Willebrand factor propeptide in adistinct subtype of recessive von Willebrand disease 显示文摘	Lanke E Kristoffersson AC Philips M	2008	Thromb Haemost2008，100，2：	1
	5	Retroperitoneoscopic or laparoscopic adrenalectomy ? A single-centre UK experience显示文摘	Vasilis AC Ioannis Christakis Philip Touska	2013	Surg Endosc2013，27，：	1
	6	Caco-2 cell monolayers as a model for drug transport across the intestinal mucosa显示文摘	Allen RH Robert AC Philip SB	1990	Pharm Res1990，7，9：	1
	7	Vi-tamin A and retinoic acid act synergistically to increase lung retinyl esters during normoxia and reduce hyperoxitc lung injury in new- born mice显示文摘	Jame ML Ross AC Bulger A Philips JB Ambalavanan N	2010	Pediatr Res2010，6，6：	1
	8	Caco-2 cell monolayers as a model for drug transport across the intestinal mucosa显示文摘	Allen RH Robert AC Philip SB		0，，09：	1
	9	Regulation and function of the P53 tumor suppressor protein显示文摘	Ryan KM Philips AC Vousden KH	2001	Curr Opin Cell Biol2001，13，：	1
	10	Tracheomalacia and tracheobronchomalacia in children and adults: an in-depth review显示文摘	Kelly AC Philip MB David AW	2005	Chest2005，127，3：	1
	11	Statins (HMG-CoA reductase inhibitors) decrease postoperative adhesions by increasing peritoneal fibrinolytie aetivity显示文摘	Cary BA Philip AC Adam G	2007	Ann Surg2007，245，2：	1
	12	Identifying risk factors in subtalar arthroereisis explantation:a propensity-matched analysis显示文摘	Emily AC Jeremy JC Philip B		0，，：	1
	13	Management of perforated peptic ulcer in a district general hospital显示文摘	Critchley AC Philips AW Bawa SM	2011	Ann RColl Surg Engl2011，93，：	1

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