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40篇 您的检索式:作者名="Peters WR"
    题名 作者 年代 出处 被引量
1Antioxidant enriched enteral nutrition and oxidative stress after major gastrointestinal tract surgery显示文摘AIM: To investigate the effects of an enteral supple-ment containing antioxidants on circulating levels of antioxidants and indicators of oxidative stress after major gastrointestinal surgery.METHODS: Twenty-one patients undergoing major upper gastrointestinal tract surgery were randomised in a single centre, open label study on the effect of postoperative enteral nutrition supplementedwith antioxidants. The effect on circulating levels of antioxidants and indicators of oxidative stress, such as F2-isoprostane, was studied. RESULTS: The antioxidant enteral supplement showed no adverse effects and was well tolerated. After surgery a decrease in the circulating levels of antioxidant parameters was observed. Only selenium and glutamine levels were restored to pre-operative values one week after surgery. F2-isoprostane increased in the first three postoperative days only in the antioxidant supplemented group. Lipopolysaccharide binding protein (LBP) levels decreased faster in the antioxidant group after surgery.CONCLUSION: Despite lower antioxidant levels there was no increase in the circulating markers of oxidative stress on the first day after major abdominal surgery. The rise in F2-isoprostane in patients receiving the antioxidant supplement may be related to the conversion of antioxidants to oxidants which raises questions on antioxidant supplementation. Module AOX restored the postoperative decrease in selenium levels. The rapid decrease in LBP levels in the antioxidant group suggests a possible protective effect on gut wall integrity. Further studies are needed on the role of oxidative stress on outcome and the use of antioxidants in patients undergoing major abdominal surgery.Mireille FM van Stijn Gerdien C Ligthart-Melis Petra G Boelens Peter G Scheffer Tom Teerlink Jos WR Twisk Alexander PJ Houdijk Paul AM van Leeuwen 2008World Journal of Gastroenterology2008,14,45:4
2Variants of toll-like receptor 4 modify the efficacy of statin therapy and the risk of cardiovascular events 显示文摘Boekholdt SM Agema WR Peters RJ 2003Circulation2003,107,19:1
3Penetration of bacteria in bovine root dentine in vitro显示文摘Peters LB Wesselink PR Moorer WR 2000Int Endod J2000,33,1:1
4Laparoscopic total proctocolectomy with creation of ileostomy for ulcerative colitis : report of two cases 显示文摘Peters WR 1992J Laparo-endosc Surg1992,2,3:1
5Potential benefits and hazards of physical activity and exer- cise on the gastrointestinal tract 显示文摘Peters HP De Vries WR Vanberge- Henegouwen GP 2001Gut2001,48,3:1
6Lapa copic total proctocolectomy with creation of ileostomy for ulcerative colitis:report of two cases显示文摘Peters WR 0,,03:1
7Variants of toll-like receptor 4 modify the efficacy of statin therapy and the risk of cardio-vascular events显示文摘Boekholdt SM Agema WR Peters RJ 2003Circulation2003,107,:1
8Leukotrienes显示文摘Peters - Golden M Henderson WR Jr 2007N Engl J Med2007,357,:1
9Concurrent chemotherapy and pelvic radiation therapy compared with pelvic radiation therapy alone as adjuvant therapy after radical surgery in high-risk early-stage cancer of the cervix显示文摘Peters WR Liu PY Barrett RN 2000J Clin Oncol2000,18,8:1
10Potential benefits and hazards of physical activity and exercise on the gastrointestinal tract 显示文摘Peters HP De Vries WR Vanberge - Henegouwen GP 2001Gut2001,48,3:1
11Leukotrienes显示文摘Peters - Golden M Henderson WR Jr 2007N Engl Med2007,357,18:1
12Inhibitors of human histone deacetylase:synthesis and enzyme and cellular activity of straight chain hydroxamates显示文摘Stacy WR Lidia CS Peter A 2002J Med Chem2002,45,4:1
13Fairly results of laparoscopic surgery for colorectal cancer: retrospective analysis of 372 patients treated by Clinical Outcomes of surgical Therapy(COST)Study Group显示文摘Fleshman JW Nelson H Peters WR 1996Dis Colon Rectum1996,39,10:1
14The development of fibrin sheath on indwelling venous catheters 显示文摘Peters WR Bush WH Mclntyre RD et at 1973Surg Gynecol Obstet1973,137,1:1
15Leukotrienes 显示文摘Peters - Golden M Henderson WR Jr 2007N Engl J Med2007,357,18:1
16STR analysis of artificially degraded DNA-results of a collaborative European exercise 显示文摘Peter MS Bender K Mayr WR 2004Forensic Sci Int2004,139,:1
17Penetration of bac- teria in bovine root dentine in vitro显示文摘Peters LB Wesselink PR Mcorer WR 2000Int Endod J2000,33,1:1
18Variants of toll -like receptor 4 modify the efficacy of statin therapy and the risk of cardio- vascular events 显示文摘Boekholdt SM1 Agema WR Peters R J 2003Circulation2003,107,:1
19Variants of toll-likereceptor 4 modify the efficacy of statin therapy and the risk of car-diovascular events显示文摘Boekholdt SM Agema WR Peters RJ 2003Circulation2003,107,19:1
20The role of leukotrienes in allergic rhinitis 显示文摘Peters - Golden M Henderson WR Jr 2005Ann Allergy Asthma Immunol2005,94,6:1
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