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258篇 您的检索式:作者名="Pereda"
    题名 作者 年代 出处 被引量
1Corrosion behaviour of AZ31 magnesium alloy with different grain sizes in simulated biological fluids显示文摘M. Alvarez-Lopez María Dolores Pereda J.A. del Valle M. Fernandez-Lorenzo M.C. Garcia-Alonso O.A. Ruano M.L. Escudero 2009Acta Biomaterialia2009,,5:3
2Protein phosphatases and chromatin modifying complexes in the inflammatory cascade in acute pancreatitis显示文摘Acute pancreatitis is an inflammation of the pancreas that may lead to systemic inflammatory response syndrome and death due to multiple organ failure. Acinar cells, together with leukocytes, trigger the inflammatory cascade in response to local damage of the pancreas. Amplification of the inflammatory cascade requires up-regulation of proinflammatory cytokines and this process is mediated not only by nuclear factor κB but also by chromatinmodifying complexes and chromatin remodeling. Among the different families of histone acetyltransferases, the p300/CBP family seems to be particularly associated with the inflammatory process. cAMP activates gene expression via the cAMP-responsive element (CRE) and the transcription factor CRE-binding protein (CREB). CREB can be phosphorylated and activated by different kinases, such as protein kinase A and MAPK, and then it recruits the histone acetyltransferase co-activator CREB-binding protein (CBP) and its homologue p300. The recruitment of CBP/p300 and changes in the level of histone acetylation are required for transcription activation. Transcriptional repression is also a dynamic and essential mechanism of down-regulation of genes for resolution of inflammation, which seems to be mediated mainly by protein phosphatases (PP1, PP2A and MKP1) and histone deacetylases(HDACs) .Class HDACs are key transcriptional regulators whose activities are controlled via phosphorylationdependent nucleo/cytoplasmic shuttling. PP2A is responsible for dephosphorylation of class HDACs, triggeringnuclear localization and repression of target genes, whereas phosphorylation triggers cytoplasmic localization leading to activation of target genes. The potential benefit from treatment with phosphodiesterase inhibitors and histone deacetylase inhibitors is discussed.Javier Escobar Javier Pereda Alessandro Arduini Juan Sastre Juan Sandoval Luis Aparisi Gerardo López-Rodas Luis Sabater 2010World Journal of Gastrointestinal Pharmacology and Therapeutics2010,1,3:2
3OSI Service Specification:SAP and CEP Modeling显示文摘JG Tomas J Pavon O Pereda 1987ACM SIGCOMM Computer Communiation Review1987,17,12:2
4Corrosion behaviour of AZ31 magnesium alloy with different grain sizes in simulated biological fluids显示文摘M. Alvarez-Lopez María Dolores Pereda J.A. del Valle M. Fernandez-Lorenzo M.C. Garcia-Alonso O.A. Ruano M.L. Escudero 2009Acta Biomaterialia2009,,5:2
5Circulating TNF-alpha and its soluble receptors during experimental acute pancreatitis显示文摘Granell S Pereda J Gomez-Cambronero L 2004Cytokine2004,25,4:1
6Computation of resonant frequencies and quality factors of open dielectric resonators by a combination of the finite difference time-domain (FDTD) and Prony's methods显示文摘PEREDA J A 1992IEEE Microwave Guided Wave Letter1992,2,11:1
7Proteolysis of ultra-high pressure homogenised treated milk during refrigerated storage显示文摘J. Pereda V. Ferragut M. Buffa B. Guamis A.J. Trujillo 2008Food Chemistry2008,,3:1
8Role of eytokines and oxidative stress in the pathophysiology of acute pancreatitis:therapeutical implications显示文摘Gómez-Cambronem LG Sabater L Pereda J at al 2002Curr Drug Targets Inflamm Allergy2002,1,4:1
9UAV Attitude estimation using unscented Kalman filter and TRIAD显示文摘de Marina H G Pereda F J Giron-Sierra J M 2012Industrial Electronics IEEE Transactions on2012,59,11:1
10PWM method to eliminate power sources in a nonredundant 27-level inverter for machine drive applications显示文摘M Rotella G Penailillo J Pereda J Dixon 0,,01:1
11Langerhans cell histiocytosis: literature reviewand descriptive analysis of oral manifes- tations 显示文摘Madrigal -Martinez -Pereda C Guerrero -Rodrfguez V Guisado-Moya B 2009Med OralPatol Oral Cir Bueal2009,14,5:1
12Effect of Mo on Dynamic Recrystallization Behavior of Nb-Mo Microalloyed Steels 显示文摘Pereda B Fernandez A I Lopez B 2007ISIJ International2007,47,6:1
1323-Level Inverter for Electric Vehicles Using a Single Battery Pack and Series Active Filters显示文摘Javier Pereda Juan Dixon 0,,03:1
14Corrosion behaviour of AZ31 magnesium alloy with different grain sizes in simulated biological fluids 显示文摘ALVAREZ-LOPEZ M PEREDA M D DEL VALLE J A FERNANDEZ-LORENZO M GARCIA-ALONSO M C RUANO OA ESCUDERO M L 2010Acta Biomaterialia2010,6,:1
15High levels of metalloproteinases regulate proliferation and hormone secretion in pituitary cells 显示文摘Paez Pereda M Ledda MF Goldberg V 2000J Clin Endocrinol Metab2000,85,1:1
16Tubulin secondary structure analysis,limited proteolysis sites,and homology to FtsZ显示文摘de Pereda JM Leynadier D Evangelio JA 1996Biochemistry1996,35,14:1
17Nerve injury induces gap junctional coupling among axotomized adult motor neusron 显示文摘Chang Q Pereda A Pinter MJ 2000J Neurosci2000,20,2:1
18Prepara- tion and characterization of sodium caseinate films reinforced with cellulose derivatives显示文摘Pereda M Amica G R6cz I 2011Ca- rbohydrate Polymers2011,86,:1
19Oestrus synchronisation of rabbit does at early post-partum by doe-litter separation or eCG injection:reproductive parameters and endocrine profiles显示文摘Rebollar P G Milanés A Pereda N 0,,:1
20Current insights into the formation and breakdown of hemidesmosomes 显示文摘Litjens SH de Pereda JM Sonnenberg A 2006Trends Cell Biol2006,16,37:1
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