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| 1 | Serrated polyposis syndrome:Molecular,pathological and clinical aspects显示文摘Hyperplastic polyps have traditionally been considered not to have malignant potential.New pathological classification of serrated polyps and recent discoveries about the serrated pathway of carcinogenesis have revolutionized the concepts and revitalized the research in this area.Until recently,it has been thought that most colorectal cancers arise from conventional adenomas via the traditional tumor suppressor pathway initiated by a mutation of the APC gene,but it has been found thatthis pathway accounts for only approximately 70%-80% of colorectal cancer(CRC)cases.The majority of the remaining colorectal cancer cases follow an alternative pathway leading to CpG island methylator phenotype carcinoma with BRAF mutation and with or without microsatellite instability.The mechanism of carcinomas arising from this alternative pathway seems to begin with an activating mutation of the BRAF oncogene.Serrated polyposis syndrome is a relatively rare condition characterized by multiple and/or large serrated polyps of the colon.Clinical characteristics,etiology and relationship of serrated polyposis syndrome to CRC have not been clarified yet.Patients with this syndrome show a high risk of CRC and both sporadic and hereditary cases have been described.Clinical criteria have been used for diagnosis and frequent colonoscopy surveillance should be performed in order to prevent colorectal cancer.In this review,we try to gather new insights into the molecular pathogenesis of serrated polyps in order to understand their possible clinical implications and to make an approach to the management of this syndrome. | Carla Guarinos Cristina Sánchez-Fortún María Rodríguez-Soler Cristina Alenda Artemio Payá Rodrigo Jover | 2012 | World Journal of Gastroenterology2012，18，20： | 8 |
| 2 | New Development of China-Russia-India Triangle显示文摘Since 2001, positive improvement has occurred in the trianglerelationship between China, Russia and India. The foreignministers of the three nations met in Russia recently, symbolizingthe launching of substantive triangular cooperation. | Ma Jiali is Research Professor at CICIR. He specializes in South Asian security, especially in India’s foreign policy. He is the author of three books, such as Pay Close Attention to India: A Rising Power which is very influential. He was one of the delegates for Track Two Dialogue between China and India for all of four rounds and a delegate for Track Two Dialogue between China, Russia and India. He is also a member of Eminent Persons Group Forum between China and India. | 2005 | Contemporary International Relations2005，15，7： | 4 |
| 3 | Characterization of a transcription terminator of the procyclin PARP A unit of Trypanosoma brucei显示文摘 | Berberof M Pays A Lips S | | 0，，03： | 1 |
| 4 | Analysis of the strain transfer in a new FBG sensor for structural health monitoring显示文摘 | Torres B Payá-Zaforteza I Calderón P A | 2011 | Engineering Structures2011，33，2： | 1 |
| 5 | Incidence and reversibility of organ failure in the course of sterile or infected necrotizing pancreatitis显示文摘 | Le Mée J Paye F Sauvanet A | 2001 | Arch Surg2001，136，12： | 1 |
| 6 | The MsK family of alfalfa protein kinase genes encodes homologues of shaggy/glycogen synthase kinase-3 and shows differential expression patterns in plant organs and development显示文摘 | Pay A Jonak C Bogre L | | 0，，06： | 1 |
| 7 | An alfalfa cDNA encodes a protein with homology to translationally controlled human tumor protein 显示文摘 | Pay A Heberle-Bors E Hirt H | 1992 | Plant Mol Biol1992，19，： | 1 |
| 8 | Plant RanGAPs arelocalized at the nuclear envelope in interphase and associated withmicrotubules in mitotic cells 显示文摘 | Pay A Resch K Frohnmeyer H | 2002 | Plant J2002，30，6： | 1 |
| 9 | Influence of zirconium on microstructure and toughness of low-alloy steel weld metals显示文摘 | Trindade V B Mello R S T Pay(a)o J C | | 0，，03： | 1 |
| 10 | Pronounced interferon-alpha production from plasmacytoid dendritic cells in patients with Behcet's disease following CpG D ODN stimulation显示文摘 | Pay S Pekel A Simsek I | | 0，，2： | 1 |
| 11 | Clinical and pathogenetie features of exposure of workers toantimonate ore显示文摘 | Labanova EA Ivanova LA Pay | 1996 | Meditsina Truda IPromyshlennaiaEk0109iia1996，4，： | 1 |
| 12 | An alfalfa eDNA encodes a protein with homology to translationally controlled human tumor protein 显示文摘 | Pay A Heberle-Bors E Hirt H | 1992 | Plant Mol Biol1992，19，： | 1 |
| 13 | Prediction of potential damage due to severe earthquakes 显示文摘 | Yticemen M3 zcebe G Pay A | 2004 | Structural Safety2004，26，3： | 1 |
| 14 | Structure- activity relationships of polymethoxyflavones and other flavonoids as inhibitorys of non - enzymic lipid peroxidation 显示文摘 | MORA A PAY M RIOS J L | 1990 | Biochem Pharmacol1990，40，4： | 1 |
| 15 | Value of prostate multipara- mettle magnetic resonance imaging for predicting biopsy results in first or repeat biopsy 显示文摘 | Habchi H Bratan F Paye A | 2014 | Clin Radiol2014，69，3： | 1 |
| 16 | Intraductal papillary mucinous tumors of the pancreas: pancreatic resections guided by preoperative morphological assessment and intraoperative frozen section examination 显示文摘 | Paye F Sauvanet A Terris B | 2000 | Surgery2000，127，5： | 1 |
| 17 | Myeloid leukemia and transmission of HPRS-103 strain of avian leukosis virus显示文摘 | Pay L N Gillespie A M Howes K | 1992 | Leukemia1992，6，： | 1 |
| 18 | Value of prostate multipara metric magnetic resonance imaging for predicting biopsy results in first or repeat biopsy显示文摘 | Ac- cessed April 20 2014 Habchi H Bratan F Paye A | 2014 | Clin Radiol2014，69，20： | 1 |
| 19 | Incidence and reversibility of organ failure in the course of sterile or infected necrotizing pancreatitis显示文摘 | Le Mee J Paye F Sauvanet A | 2001 | Arch Surg2001，136，： | 1 |
| 20 | Incidence and reversibility of organ failure in the course of sterile or infected necrotizing pancreatitis显示文摘 | Le Mée J Paye F Sauvanet A | 2001 | Arch Surg2001，136，12： | 1 |
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