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88篇 您的检索式:作者名="Paumgartner"
    题名 作者 年代 出处 被引量
1Medical treatment of cholestatic liver diseases:From pathobiology to pharmacological targets显示文摘胆汁分泌物依赖于很多个肝胆管运输系统的协调函数。胆汁郁积可以被胆汁分泌物,胆汁流动的阻塞或二的联合的一个缺陷引起。胆汁郁积的所有形式的普通后果在导致 hepatocytes 并且最后的 apoptosis 或坏死到长期的胆汁郁积的肝疾病的 hepatocytes 是胆汁酸和另外的潜在地有毒的混合物的保留。在某些胆汁郁积的混乱,也有进仙子的胆汁酸的漏胆汁的空间引起门发炎和纤维变性。为肝内胆汁郁积的处理的下列药理学目标能被识别:身体笔直的胆汁的分泌物的刺激并且后退进为经由肾到的排泄的全身的发行量的胆汁酸和另外的有毒的 cholephils 的分泌物在 hepatocytes 减少他们的保留;到更吸水的、不太有毒的代谢物的恐水病的胆汁酸和另外的有毒的混合物的新陈代谢的刺激;对胆汁的有毒的效果的受伤 cholangiocytes 的保护;apoptosis 的抑制由细胞毒素的胆汁酸的提高的层次引起了;纤维变性的抑制由胆汁酸的漏引起了进仙子胆汁的空间。主要胆汁性肝硬变的 ursodeoxcholic 酸治疗的临床的结果可以被认为是这策略的第一成功。Gustav Paumgartner 2006World Journal of Gastroenterology2006,12,28:13
2Ursodeoxycholic acid in cholestatic liver disease: Mechanisms of action and therapeutic use revisited显示文摘Gustav Paumgartner Ulrich Beuers 2002Hepatology2002,,3:2
3Glutathione protects the rat liver against reperfusion injury after hypothermic preservation显示文摘Bilzer M Paumgartner G Gerbes A L 1999Gastroenterol1999,117,:1
4Ursodeoxycholc acid in cholestatic liver disease mechanisms of action and therapeutic use revisit显示文摘Paumgartner G Beuers U 2002Hepatology2002,36,:1
5Ursodeoxycholic acid in cholestatic Liver divease:mechanisms of action and thereapeutic use revisited显示文摘PAUMGARTNER G BEUERS U 2002Hepatology2002,36,3:1
6Ursedeoxycholic acid in cholestatic liver disease: mechanisms of action and therapeutic use revisited显示文摘Paumgartner G Beuers U 2002Hepatology2002,36,:1
7Medica 1 treatment of cholestatic liverd isease显示文摘Paumgartner G Pusl T 2008Clin Liver Dis2008,12,1:1
8Medical treatment of cholestatic liverdisease显示文摘Paumgartner G Pusl T 2008Clin Liver Dis2008,12,1:1
9Hepatobiliary transport 显示文摘Kullak-Ublick G A Beuers U Paumgartner G 2000J Hepatol2000,32,1:1
10Medical treatment of cholestatic live disease显示文摘Paumgartner Pusl T 2008Clin Liver Dis2008,12,1:1
11Hepatobiliary transport 显示文摘Kullak Ublick G A Beuers U Paumgartner G 2000J Hepatol2000,32,11:1
12Medical treatment of cholestatic liver disease显示文摘Paumgartner G Pusl T 2008Clin Liver Dis2008,12,1:1
13Ursodeoxycholic acid in cholestasis: potential mechanisms of action and thepapeitic applications显示文摘Beuers U Boyer JL Paumgartner G 1998Hepatology1998,28,6:1
14Stable expression and functional characterization of a Na+-taurocholate cotransporting green fluorescent protein in human hepatoblastoma HepG2 cells显示文摘Gerd A. Kullak-Ublick Manfred G. Ismair Ralf Kubitz Marcus Schmitt Dieter H?ussinger Bruno Stieger Bruno Hagenbuch Peter J. Meier Ulrich Beuers Gustav Paumgartner 2000Cytotechnology (-)2000,,1:1
15Hepatobiliary transport显示文摘Kullak-Ublick G A Beuers U Paumgartner G 2000J Hepatol2000,32,1:1
16Hepatobiliary transport 显示文摘Kullak-Ublick GA Beuers U Paumgartner G 2000J Hepatol2000,32,1:1
17Medical treatment of cholestatic liver disease显示文摘Paumgartner G Pusl T 2008ClinLiverDis2008,12,1:1
18Ursodeoxycholic acid in cholestatic liver disease: mechanisms of action and therapeutic use revisited 显示文摘Paumgartner G Beuers U 2002Hepatology2002,36,:1
19Medical treatment of cholestatic liver disease显示文摘PAUMGARTNER G PUSL T 2008Clin Liver Dis2008,12,:1
207 alphadehydroxylating bacteria enhance deoxyeholic acid input and cholesterol saturation of bile in patients with gallstones显示文摘Berr F Kullak-Ublick G A Paumgartner G 1996Gastroenterology1996,111,6:1
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