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| 1 | Superior safety of direct oral anticoagulants compared to Warfarin in patients with atrial fibrillation and underlying cancer: a national veterans affairs database study显示文摘Background Studies evaluating safety of warfarin and direct oral anticoagulants(DOACs) for prevention of stroke in patients with atrial fibrillation(AF) are lacking. Methods & Results All patients(n = 196,521) receiving care at veteran’s affairs with active cancer and AF from 2010–2015 were included. One-year mortality was significantly higher in unadjusted analysis with warfarin(44.9%) compared to dabigatran(25%, P < 0.001), rivaroxaban(24.4%, P < 0.001) and apixaban(30%, P < 0.001) and after adjusting for age, sex and type of cancer mortality(OR = 2.66, 95% CI: 2.52–2.82, P < 0.001). Risk of ischemic stroke(13.5% vs. 11.1%, 12.0%, 14.0%) was similar, however risk of hemorrhagic stroke was significantly higher among patients receiving warfarin(1.2%) compared to patients receiving dabigatran(0.5%), rivaroxaban(0.7%) and apixaban(0.8%) respectively, P = 0.04. Conclusions We demonstrated the superior safety profile of DOACs compared to warfarin among patients with underlying cancer and AF. Warfarin was associated with higher mortality, similar ischemic stroke risk but higher risk of hemorrhagic stroke. | Abhishek C Sawant Arnav Kumar Wilmon Mccray Sheldon Tetewsky Linda Parone Srilekha Sridhara Meghana Prakash Hiriyur Prakash Gary Tse Tong LIU Nidhi Kanwar Aishwarya Bhardwaj Sahoor Khan Christopher Manion Ankush Lahoti Ashish Pershad Peter Elkin John Corbelli | 2019 | Journal of Geriatric Cardiology2019，16，9： | 2 |
| 2 | A differential proteomic approach to identify proteins associated with thyroid cell transformation显示文摘 | Paron I D′Ambrosio C Scaloni A | | 0，，01： | 1 |
| 3 | A proteomic approach to identify early molecular targets of oxidative stress in human epithelial lens cells显示文摘 | Paron I D'Elia A D'Ambrosio C | 2004 | Biochem J2004，378，3： | 1 |
| 4 | Distribution of Taenia saginata cysticerci in tissues of experimentally infected cattle显示文摘 | Brad Scandrett Sarah Parker Lorry Forbes Alvin Gajadhar Paron Dekumyoy Jitra Waikagul Deborah Haines | 2009 | Veterinary Parasitology2009，，2： | 1 |
| 5 | A proteomic approach to identify early molecular targets of oxidative stress in human epithelial lens cells 显示文摘 | Paron I D'Elia A D'Ambrosio C | 2004 | Biochem2004，378，3： | 1 |
| 6 | Attributes of suc-cessful nurse executive: survey of nurse and their mentors 显示文摘 | Parons RJ Fosbinder D Murra YD | 1998 | JNurs Adm1998，28，7： | 1 |
| 7 | Secondary flow in cascades of highly loaded turbine blades 显示文摘 | MOUSTAPHA S H PARON G J WADE J H T | 1985 | ASME Journal of Engineering for Gas Turbine and Power1985，105，10： | 1 |
| 8 | Mitochondria: regulating the inevitable 显示文摘 | Parone PA James D Martinou JC | 2002 | Biochimie2002，84，23： | 1 |
| 9 | Nuclerr localization of galectin3 in transformed thyroid cells: a role in transcriptional regulation显示文摘 | PARON I SCALONI A PINES A | 2003 | BBRC2003，302，： | 1 |
| 10 | Mitochondrial release of apoptosis-inducing factor occurs downstream of cytochrome crelease in response to several proapoptotic stimuli显示文摘 | Parone P Martinou JC et al | 2002 | J Cell Biol2002，159，： | 1 |
| 11 | Acid phospha- tase activity in pre- and post-spawning hake(Merluc-ciushubbsi)显示文摘 | Goldemberg A L Paron L Crupkin M | 1987 | Comparative Biochemistry and Physi- ology-Part A1987，，87： | 1 |
| 12 | Matrix metalloproteinases显示文摘 | Parons SL Watson SA Brown PD | 1997 | Br J Surg1997，84，2： | 1 |
| 13 | Apoptosis: bombarding the mitochondria 显示文摘 | Parone P Priault M James D | 2003 | Essays Biochem2003，39，： | 1 |
| 14 | Preventing mitochondrial fission impairs mitochondrial function and leads to loss of mitochondrial DNA显示文摘 | Parone PA Da Cruz S Tondera D | 2008 | PLo S ONE2008，，： | 1 |
| 15 | Mechanisms of mitochondrial outer membrane permeabilization 显示文摘 | James D Parone PA Terradillos O | 2007 | Novartis Found Symp2007，287，： | 1 |
| 16 | Matrix metalloproteinases 显示文摘 | Parons SL Watson SA Brown PD | 1997 | Br J Surg1997，84，2： | 1 |
| 17 | Agents that reason and negotiation by arguing 显示文摘 | Parons S Sierra C A Jennings N R | 1998 | Journal of Logic and Computation1998，8，3： | 1 |
| 18 | Acid phosphataseactivity in pre- and post-spawning hake (Merluccius hubbsi) 显示文摘 | Goldemberg A L Paron L Crupkin M | 1987 | Comparative Biochemistry and Physiology-Part A: Molecular & Integrative Physiology1987，87，4： | 1 |
| 19 | SLP -2 inter- acts with prohibitins in the mitoehondrial inner membrane and contributes to their stability显示文摘 | Da Cruz S Parone PA Gonzalo P | 2008 | Biochim Biophys Ac- ta2008，1783，5： | 1 |
| 20 | Rapid and reversible inhibitor of tyrosinase activity by glycosidase inhibitor in human melanoma cell 显示文摘 | Takahashi H Parons P G | 1992 | Invest Dermatol1992，98，： | 1 |
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