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| 1 | Role of melatonin on diabetes-related metabolic disorders显示文摘Melatonin is a circulating hormone that is mainly re- leased from the pineal gland. It is best known as a regulator of seasonal and circadian rhythms, its levels being high during the night and low during the day. Interestingly, insulin levels are also adapted to day/night changes through melatonin-dependent synchronization. This regulation may be explained by the inhibiting action of melatonin on insulin release, which is transmitted through both the pertussis-toxin-sensitive membrane receptors MT1 and MT2 and the second messengers 3',5' -cyclic adenosine monophosphate, 3',5'-cyclic guanosine monophosphate and inositol 1,4,5-trisphosphate. Melatonin may influence diabetes and associated metabolic disturbances not only by regulating insulin secretion, but also by providing protection against reactive oxygen species, since pancreatic β-cells are very susceptible to oxidative stress because they possess only low-antioxidative capacity. On the other hand, in several genetic association studies, single nucleotide polymorphysms of the human MT2 receptor have been described as being causally linked to an elevated risk of developing type 2 diabetes. This suggests that these individuals maybe more sensitive to the actions of melatonin, thereby leading to impaired insulin secretion. Therefore, block- ing the melatonin-induced inhibition of insulin secretion may be a novel therapeutic avenue for type 2 diabetes. | Javier Espino José A Pariente Ana B Rodríguez | 2011 | World Journal of Diabetes2011，2，6： | 11 |
| 2 | Placental abruption:critical analysis of risk factors and perinatal outcomes显示文摘 | Pariente G Wiznitzer A Sergienko R | 2011 | J Matern Fetal Neonatal Med2011，24，5： | 1 |
| 3 | Role of mitochondria in Ca2+ oscillations and shape of Ca2+ signals in pancreatic acinar cells显示文摘 | Camello-Almaraz C Salido G M Pariente J A | 2002 | Biochem Pharmacol2002，63，2： | 1 |
| 4 | Pla- cental abmption:critical analysis of risk factors andperinatal outcomes 显示文摘 | Pariente G Wiznitzer A Sergienko R | 2011 | J Matem Fetal Neonatal Med2011，24，5： | 1 |
| 5 | Treatment of a wastewater from a pesticide manufacture by combined coagulation and Fenton oxidation显示文摘 | PLIEGO G ZAZO J A PARIENTE M I | 2014 | Environ Sci Pollut Res2014，21，12： | 1 |
| 6 | A Reputation-based Trust Management System for P2P Networks显示文摘 | Selcuk A Uzun E Pariente M | 2008 | International Journal of Network Security2008，6，3： | 1 |
| 7 | Insulin-like factor-1 and IGF binding protein-3 remain high after GnRH analogue therapy in girls with central Precocious puberty显示文摘 | Kanety H Karasik A Pariente C | 1996 | Clin Endocrinol(Oxf)1996，45，1： | 1 |
| 8 | Synthesis of an ultralarge pore titanium silicate isomorphous to MCM-41 and its application as a catalyst for selective oxidation of hydrocarbons显示文摘 | Corma A Navarro M T Pariente J P | 1994 | J Chem Soc Chem Commun1994，，2： | 1 |
| 9 | Synthesis of an ultra- large pore titanium silicate isomorphous to MCM-41 and its application as a catalyst for selective oxidation of hydrocarbons显示文摘 | Corma A Navarro M T Pariente J P | 1994 | J Chem Soc Chem Commun1994，，： | 1 |
| 10 | Synthesis of an Ultralarge Pore Titanium Silicate Isomorphous to MCM - 41 and Its Application as a Catalyst for Selective Oxidation of Hydrocarbous显示文摘 | Corma A Navarro M T Perez Pariente J | 1994 | J Chem Soc Chem Commun1994，，： | 1 |
| 11 | Factors influencing accuracy of CT-guided percutaneous biopsy of pulmonary lesion 显示文摘 | Montaudon M Latrabe V Pariente A | 2004 | Eur Radiol2004，14，7： | 1 |
| 12 | The influence of shot peening on the fatigue behaviour of duplex stainless steels显示文摘 | SANJURJO P RODRGUEZ C PARIENTE I F BELZUNCE F J CANTELI A F | | 0，，01： | 1 |
| 13 | Synthesis of an Ultralarge Pore Titanium Silacate Isomorphous to MCM-41 and Its Application as a Catalyst for Selective Oxidation of Hydrocarbons显示文摘 | Corma A Navarro M T Pariente J P | 1994 | Journal of the Chemical Society Chemical Communications1994，2，： | 1 |
| 14 | Factors influencing ac- curacy of CT-guided percutaneous biopsies of pulmonary lesions 显示文摘 | Montaudon M Latrabe V Pariente A | 2004 | Eur Radiol2004，14，7： | 1 |
| 15 | Antipsychotic use and myocardial infarction in older patients with treated dementia 显示文摘 | Pariente A Fourrier - R6glat A Ducruet T | 2012 | Arch Intern Med2012，172，8： | 1 |
| 16 | In vitro biocompatibility assessment of natural y derived and synthetic biomaterials using normal human urothelial cel s显示文摘 | Pariente JL Kim BS Atala A | | 0，，01： | 1 |
| 17 | In vitro biocompatibility evaluation of natural y derived and synthetic biomaterials using normal human bladder smooth muscle cel s显示文摘 | Pariente JL Kim BS Atala A | | 0，，04： | 1 |
| 18 | Synthesis of an ultralarge pore titanium silicate isomorphous to MCM-41 and its application as a catalyst for selective oxidation of hydrocarbons 显示文摘 | CORMA A NAVARRO M T PARIENTE J P | 1994 | J Chem Soc Chem Comman1994，21，： | 1 |
| 19 | Synthesis of an ultralarge pore titanium silicate isomorphous to MCM-41 and its application as a catalyst for selective oxidation of hydrocarbon显示文摘 | Corma A Navarro M T Pariente J Perez | 1994 | Chem Soc Chem Common1994，，： | 1 |
| 20 | Synthesis of an ultralarge pore titanium silicate isomorphous to MCM-41 and its application as a catalyst for selective oxidation of hydrocarbons 显示文摘 | Corma A Navarro M T Pariente J P | 1994 | J Chem Soc Chem Commun1994，，2： | 1 |
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