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124篇 您的检索式:作者名="Parameswaran A"
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1Sam68 is a regulator of Toll-like receptor signaling显示文摘由像使用费的受体(TLR ) 的病原体的识别激活定制装主要有免疫力的回答,发炎,房间幸存和 apoptosis 的基因的多重发信号的串联和表情。尽管小径的导致 TLR 的激活,例如原子因素 kappaB (NF-κ B ) 并且激活 mitogen 的蛋白质 kinases (MAPK ) ,在有免疫力的回答期间控制这些小径的量的规定的很好被学习的、分子的实体仍然保持糟糕定义。我们作为导致 TLR 的 NF-κ 的一个新奇管理者识别了 Sam68; B 和 MAPK 激活。我们发现 TLR2 和 TLR3 完全是依赖的,而 TLR4 部分仅仅依赖于导致 NF-κ 的激活的 Sam68; B c-Rel。Sam68 的缺席极大地减少了导致 TLR2 、导致 TLR3 的 NF-κ B p65 激活,而以一种 Sam68 独立的方式的导致 TLR4 的 p65 激活。相反,因为 Sam68 的缺席提高了细胞外的调整信号的 kinases (英皇家空军之阶级最低之兵) 和 c6 月 N 终端 kinases (JNK ) 的导致 TLR2 的激活, Sam68 看起来是 MAPK 小径的一个否定管理者。有趣地,导致 TLR2 、导致 TLR3 的基因表示显示出 Sam68 的一个微分要求。Sam68 的缺席损害了导致 TLR2 的基因表示,建议 Sam68 有在 myeloid 区别的一个关键角色主要反应基因 88 依赖者 TLR2 发信号。导致 TLR3 的基因表示利用 Toll/ Interleukin-1 receptor-domain-containing 导致改编者的贝它干扰素小径,仅仅部分取决于 Sam68。我们的调查结果建议 Sam68 可以作为平衡 NF-κ 的激活的一个有免疫力的变阻器工作; B p65 和 c-Rel,以及 MAPK,揭示一个潜在的新奇目标操作 TLR 发信号。Jeffrey A Tomalka Tristan J de Jesus Parameswaran Ramakrishnan 2017Cellular & Molecular Immunology2017,14,1:3
2Scanning electronmicroscopic, and energy dispersive spectrometric investigations on the effect of XeCl excimer laser on human dentin with Smear layer显示文摘Kumar AR Rao CV Parameswaran A 2002J Oral Rehabil2002,29,10:1
3Dynamic fracture of a functionally gradient material having discrete property variation显示文摘Parameswaran V Shukla A 1998Journal of Materials Science1998,33,13:1
4A Cross- National Comparison of Consumer Research Measures 显示文摘Parameswaran R Yaprak A 1987Journal of International Business Studies1987,18,1:1
5A comparison of canal preparation using the K - file and Lightspeed in resin blocks显示文摘Thamni SL Parameswaran A Sukumaran VG 1996JEndod1996,22,:1
6Do sphe- noidal electrodes aid in surgical decision making in drug re- sistant temporal lobe epilepsy? 显示文摘Cherian A Radhakrishnan A Parameswaran S et a~ 2012Clin Neurophysiol2012,,3:1
7Intrasellar paraganglioma:report of a case in a sibship of HippelLindau disease显示文摘Scheithauer B Parameswaran A Burdick B 1996Neurosurgery1996,38,:1
8Comparison of creep rupture behaviour oftype 316L(N) austenitic stainless steel joints welded by TIG andactivated TIG welding processes显示文摘SAKTHIVEL T VASUDEVAN M LAHA K PARAMESWARAN P CHANDRAVATHI K S MATHEW MD BHADURI A K 2011Materials Science andEngineering A2011,528,2223:1
9Microstructural investigations into the low cycle fatigue deformation of a Cu-Cr-Zr-Ti alloy显示文摘Nagesha A Parameswaran P Biswas A 2013Materials Science and Engineer A2013,582,10:1
10Pin tract infection with contemporary external fixation: How much of a problem显示文摘Parameswaran A D Craig S R Seligson D 2003Journal of Orthopaedic Trauma2003,17,7:1
11Dynamic fracture of a functionally graded material having discrete property variation显示文摘Parameswaran V Shulda A 1998Journal of Materials Science1998,31,6:1
12Effectiveness of prophylactic use of rofecoxib in comparison with ibuprofen on postendodontic pain 显示文摘Gopikfishna V Parameswaran A 2003J Endod2003,29,1:1
13Evaluation of energy-conversion efficiencies in microbial fuel cells (MFCs) utilizing fermentable and non-fermentable substrates显示文摘LEE H S PARAMESWARAN P KATO-MARCUS A 2008Water Research2008,42,67:1
14Role of extracellular matrix and its regulation in human airway smooth muscle biology 显示文摘Parameswaran K Willems-Widyastuti A Alagappan V K 2006Cell Biochem Biophys2006,44,1:1
15Evalu- ation of energy-conversion efficiencies in microbial fuel cells (MFCs) utilizing fermentable and non-fermentable substrates 显示文摘LEE H S PARAMESWARAN P KATO-MARCUS A 2008Water Re- search2008,42,67:1
16Recommendation systems with complex con- straints: A course recommendation perspective 显示文摘PARAMESWARAN A VENETIS P GARCIA- MO- LINA H 2011ACM Transactions on Information Systems2011,29,4:1
17Cadmiuminduced inhibition of photosynthesis and long-term acclimation to cadmium stress in the hyperaccumulator Thlaspi caerulescens显示文摘KUPPER H PARAMESWARAN A LEITENMAIER B 2007New Phytologist2007,175,:1
18Kinetic experiments for evaluating the Nemst-Monod model for anode- respiring bacteria (ARB) in a biofilm anode显示文摘TORRES C I MARCU A K PARAMESWARAN P 2008Environmental Sci- ence & Technology2008,42,17:1
19Cadmium-induced inhibition of photosynthesis and long-term acclimation to cadmium stress in the hyperaccumulator Thlaspi caerulescens显示文摘K(U)PPER H PARAMESWARAN A LEITENMAIER B 2007New Phytologist2007,175,:1
20Crack-tip stress fields for dynamic fracture in functionally gradient materials显示文摘Parameswaran V Shukla A 1999Mechanics of Materials1999,31,:1
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