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419篇 您的检索式:作者名="Pappa N"
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1Pancreatic insulinoma:current issues and trends显示文摘BACKGROUND:Although insulinomas are very rare tumors, they are the most common pancreatic neuroendocrine neoplasms.The incidence in general population is 1-4 per 1 000 000 yearly but the incidence is higher in autopsy studies. The malignancy of insulinomas is difficult to be predicted on the basis of their histological features,and the current WHO classification has been re-evaluated.This review aimed to summarize classical knowledge with current trends in the diagnosis and treatment of insulinomas. DATA SOURCES:A Medline search using terms'insulinoma', 'treatment'and'neuroendocrine tumors'was conducted. Additional references were sourced from key articles. RESULTS:Surgery is the treatment of choice for insulinoma and has an extremely high success rate.Medical treatment is also available but only for patients who are unable or unwilling to undergo surgical treatment.Preoperative localization is necessary for planning the surgical approach.Many methods exist for localization of an insulinoma and can be invasive and non-invasive.The combination of biphasic thin section helical CT and endoscopic ultrasonography(EUS)has an almost 100% sensitivity in localizing insulinomas.Laparoscopic ultrasound is mandatory to localize intraoperatively these tumors.EUS-guided fine needle tattoing is an alternative method of localization in case of lack of laparoscopic ultrasound. CONCLUSION:Laparoscopic resection for benign insulinomas is the procedure of choice,whereas pancreatectomy is reserved for large,potentially malignant tumors.Dennis Vaidakis John Karoubalis Theodora Pappa George Piaditis George N Zografos 2010Hepatobiliary & Pancreatic Diseases International2010,9,3:22
2Surgical management of necrotizing pancreatitis:An overview显示文摘Necrotizing pancreatitis is an uncommon yet serious complication of acute pancreatitis with mortality rates reported up to 15%that reach 30%in case of infection.Traditionally open surgical debridement was the only tool in our disposal to manage this serious clinical entity.This approach is however associated with poor outcomes.Management has now shifted away from open surgical debridement to a more conservative management and minimally invasive approaches.Contemporary approach to patients with necrotizing pancreatitis and/or infectious pancreatitis is summarized in the 3Ds:Delay,Drain and Debride.Patients can be managed in the intensive care unit and any intervention should be delayed.Percutaneous drainage can be utilized first and early in the course of the disease,followed by endoscopic drainage or video assisted retroperitoneoscopic drainage if necrosectomy is deemed necessary.Open surgery is now less frequently performed and should be reserved for cases refractory to any other approach.The management of necrotizing pancreatitis therefore requires a multidisciplinary dynamic model of approach rather than being a surgical disease.George Kokosis Alexander Perez Theodore N Pappas 2014World Journal of Gastroenterology2014,20,43:16
3Terlipressin improves pulmonary pressures in cirrhotic patients with pulmonary hypertension and variceal bleeding or hepatorenal syndrome显示文摘Terlipressin has been shown to improve both pulmonary and systemic hemodynamics in stable cirrhotic patients with pulmonary hypertension,whereas other vasoconstrictors may cause pulmonary pressures to deteriorate We investigated the pulmonary and systemic hemodynamic effects of the first terlipressin dose(2 mg) in 7 cirrhotic patients with PH presenting with variceal bleeding(n=4) or hepatorenal syndrome(n=3).Terlipressin decreased pulmonary vascular resistance(158.8±8.9 vs 186.5±13.9 dynes sec cm-5 ;P=0.003) together with an increase in systemic vascular resistance(2143± 126 vs 1643±126 dynes sec cm-5 ;P<0.001).Terlipressin should be the vasoconstrictor treatment of choice when patients present with variceal bleeding or HRS.George N Kalambokis Konstantinos Pappas Epameinondas V Tsianos 2012Hepatobiliary & Pancreatic Diseases International2012,11,4:4
4Phannaceutical agents known to produce disulfiram-like reaction:effects Oil hepatic ethanol metabolism and brain monoamines显示文摘KABAMANAKOS P N PAPPAS P BOUMBA V A 2007Jut J Toxicol2007,26,:1
5Inflammatory biomarkers in coronary artery disease 显示文摘Zakynthinos E Pappa N 2009J Cardiol2009,53,3:1
6Some experiences with the eigensystem realization algorithm 显示文摘Pappa R S Juang J N 1988Sound and Vibration1988,22,1:1
7An eigensystem realization algorithm for modal parameter identification and model reduction 显示文摘Juang J N Pappa R S 1985J Guidance Control and Dynamics1985,8,5:1
8Inflammatory biomarkers in coronary artery disease 显示文摘Zakynthinos E Pappa N 2009J Cardiol2009,53,3:1
9An eigensystem realization algorithm for modal parameter identification and model reduction显示文摘Juang J N Pappa R S 1985Journal of Guidance Control and Dynamics1985,8,5:1
10Structure texture similarity metrics for image analysis and retrieval显示文摘Zujovic J Pappas T N Neuhoff D L 2013IEEE Transactions on Image Processing2013,22,7:1
11Impro vement of biodiesel production based on the application of ultrasound: Monitoring of the procedure by FTIR spectroscopy显示文摘Siatis N G Kimbaris A C Pappas C S 2006JAOCS2006,83,1:1
12An Eigen system Realization Algorithm (ERA) for modal parameter identification and model reduction 显示文摘Juang J N Pappa R S 1985Guidance Control and Dynamics1985,8,5:1
13Fractures of the tibia1 pilon显示文摘MAST J W SPIEGEL P G PAPPAS J N 1988Clin Orthop1988,,230:1
14Noninvasive Identification of the Unstable Carotid Plaque显示文摘Brajesh K. Lal Robert W. Hobson Meera Hameed Peter J. Pappas Frank T. Padberg Zafar Jamil Walter N. Durán 2006Annals of Vascular Surgery2006,,2:1
15Inflammatory biomarkers in coronary artery disease显示文摘Zakynthinos E Pappa N 2009J Cardiol2009,53,3:1
16An eigensystem realization algorithm for modal parameter identification and model reduction 显示文摘Juang J N Pappa R S 1985Journal of Guidance Control and Dynamics1985,8,:1
17Mechanisms of major biliary during laparoscopic holecystectomy显示文摘Andseny A M Pappas T N Murrag E A 1992Ann Surg1992,215,:1
18An Eigensystem Realization Algorithm for Modal Parameter Identification and Model Reduction 显示文摘Juang J N Pappa R S 1985Journal of Guidance Control and Dynamics1985,8,5:1
19Efforts to create an artificial testis: culture systems of male germ cells under biochemical conditions resembling the seminiferous tubular biochemical environment显示文摘Sofikitis N Pappas E Kawatani A 2005Hum Reprod Update2005,11,3:1
20Gestational diabetes exhibits lack of carnitine deficiency despite relatively low carnitine levels and alterations in ketogenesis 显示文摘Pappa K I Anagnou N P Salanmlekis E 2005J Matem Fetal Neonatal Med2005,17,1:1
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