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| 1 | 血管性认知损害诊断的进一步规范化:血管性认知损害分类共识研究组指南显示文摘引言血管性认知损害(vascular cognitive impairment,VCI)诊断共识的缺乏(体现为多种不同评估方案的使用),妨碍了对其理解和治疗的推进.多个国家的大量临床医生和研究人员参与了2个阶段血管性认知损害分类共识研究(Vascular Impairment of Cognition Classification Consensus Study,VICCCS),旨在就VCI的诊断原则(VICCCS-1)和诊断方案(VICCCS-2)达成一致意见.本文提供了VICCCS-2的相关内容.方法使用VICCCS-1达成的原则和已发表的诊断指南作为在线德尔菲(Delphi)调查的参考基点,以期对VCI的临床诊断达成共识.结果共进行了6轮调查,每轮有65~79名专家参与,他们就VICCCS修订的轻度和重度VCI的诊断指南达成共识,并肯定了美国国立神经疾病与卒中研究所-加拿大卒中网(National Institute of Neurological Disorders and Stroke–Canadian Stroke Network,NINDS-CSN)发布的神经心理学评估方案和对影像学检查的推荐意见.讨论VICCCS-2建议规范化应用NINDS-CSN推荐的神经心理学和影像学评估方案诊断VCI,以促进研究协作. | Olivia A. Skrobot Sandra E. Black Christopher Chen Charles DeCarli Timo Erkinjuntti Gary A. Ford Rajesh N. Kalaria John O'Brien Leonardo Pantoni Florence Pasquier Gustavo C. Roman Anders Wallin Perminder Sachdev Ingmar Skoog the VICCCS group Yoav Ben-Shlomo Anthony P. Passmore Seth Love Patrick G. Kehoe 朱婷珂 徐俊 | 2018 | 国际脑血管病杂志2018，26，4： | 58 |
| 2 | Cerebral small vessel disease: from pathogenesis and clinical characteristics to therapeutic challenges显示文摘 | Leonardo Pantoni | 2010 | Lancet Neurology2010，，7： | 4 |
| 3 | Visual rating scales for age-related white matter changes (leukoaraiosis): can the heterogeneity be reduced? 显示文摘 | Pantoni L Simoni M Pracucci G | 2002 | Stroke2002，33，12： | 1 |
| 4 | Persistent impairment of gait performances and working memory after bilateral common carotid artery occlusion in the adult Wistar rat显示文摘 | Sarti C Pantoni L Bartolini L | 2002 | Behav Brain Res2002，136，1： | 1 |
| 5 | Cerebral small vessel disease:from pathogenesis and clinical characteristics to therapeutic challenges显示文摘 | Pantoni L | 2010 | The Lancet Neurology2010，9，7： | 1 |
| 6 | Efficacy and safety of nimodipine in subcortical vascular dementia: a subgroup analysis of the Scandinavian Multi-Infarct Dementia Trial显示文摘 | Pantoni L Rossi R Inzitari D | 2000 | J Neurol Sci2000，175，2： | 1 |
| 7 | Leukoaraiosis predicts hidden global functioning impairment in nondisabled older people: the LADIS (Leukoaraiosis and Disability in the Elderly) Study显示文摘 | Pantoni L Poggesi A Basile A M | 2006 | J Am Geriatr Soc2006，54，7： | 1 |
| 8 | Efficacy and safety of nimodipine in modipine in subcortical vascular dementia: a randomized placebo-controlled trial显示文摘 | Pantoni L del Ser T Soglian AG | 2005 | Stroke2005，36，3： | 1 |
| 9 | The Selective A2A Receptor Antagonist SCH 58261 Reduces Striatal Transmitter Outflow, Turning Behavior and Ischemic Brain Damage Induced by Permanent Focal Ischemiain the Rat显示文摘 | MELANI A PANTONI L BORDONI F | 2003 | Brain Res(S0006-8993)2003，959，2： | 1 |
| 10 | Lovastatin and phenylacetate inhibit the induction of nitric oxide synthase and cytokines in rat primary astrocytes, micreoglia ,and macrophages显示文摘 | Pantoni L Sheikh FG Namboodiri AMS | 1997 | J Clin Invest1997，100，11： | 1 |
| 11 | Cerebral small vessel disease: from pathogenesis and clinical characteristics to therapeutic challenges显示文摘 | Pantoni L | 2010 | Lancet Neurol2010，9，7： | 1 |
| 12 | Cerebral small vessel disease:from pathoge- nesis and clinical characteristics to therapeutic chaUe- nges显示文摘 | Pantoni L | 2010 | Lancet Neurol2010，9，7： | 1 |
| 13 | Research criteria for subcortical vascular dementia in clinical trials 显示文摘 | Erkinjuntti T lnzitari D Pantoni L | 2000 | J Neural Transm Suppl2000，59，： | 1 |
| 14 | Research criteria for subcortical vascular dementia in clinical trials显示文摘 | Erkinjuntti T Inzitari D Pantoni L | 2000 | J Neural Transm Suppl2000，59，1： | 1 |
| 15 | Cerebral small vessel disease:from pathogenesis and clinical characteristics to therapeutic challenges显示文摘 | Pantoni L | 2010 | Lancet Neurol2010，9，： | 1 |
| 16 | Pathophysiology of age - related cerebral white matter changes 显示文摘 | Pantoni L | 2002 | Cerebrovasc Dis2002，132，： | 1 |
| 17 | Progressive stroke in pontine infarction显示文摘 | Saia V Pantoni L | 2009 | Acta Neurol Scand2009，120，4： | 1 |
| 18 | Research criteria for subcortical vascular dementia in clinical trials 显示文摘 | Erkinjuntti T Inzitari D Pantoni L | 2000 | J Neural Transm2000，，： | 1 |
| 19 | The effect of white matter lesions on cognition in the elderlysmall but detectable显示文摘 | Frisoni G B Galluzzi S Pantoni L | | 0，，11： | 1 |
| 20 | Cerebral small vessel disease: from pathogenesis and clinical characteristics to therapeutic challenges 显示文摘 | Pantoni L | 2010 | Lancet Neurol2010，9，7： | 1 |
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