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	题名	作者	年代	出处	被引量
1	Comparison of the chloride channel activator lubiprostone and the oral laxative Polyethylene Glycol 3350 on mucosal barrier repair in ischemic-injured porcine intestine显示文摘AIM: To investigate the effects of lubiprostone and Polyethylene Glycol 3350 (PEG) on mucosal barrier repair in ischemic-injured porcine intestine. METHODS: Ileum from 6 piglets (approximately 15 kg body weight) was subjected to ischemic conditions by occluding the local mesenteric circulation for 45 min in vivo. Ileal tissues from each pig were then harvested and mounted in Ussing chambers and bathed in oxygenated Ringer's solution in vitro. Intestinal barrier function was assessed by measuring transepithelial electrical resistance (TER) and mucosal-to-serosal fluxes of 3H-mannitol and 14C-inulin. Statistical analyses of data collected over a 120-min time course included 2-way ANOVA for the effects of time and treatment on indices of barrier function. RESULTS: Application of 1 μmol/L lubiprostone to the mucosal surface of ischemic-injured ileum in vitro induced significant elevations in TER compared to non-treated tissue. Lubiprostone also reduced mucosal-to-serosal fluxes of 3H-mannitol and 14C-inulin. Alternatively,application of a polyethylene laxative (PEG,20 mmol/L) to the mucosal surface of ischemic tissues significantly increased flux of 3H-mannitol and 14C-inulin. CONCLUSION: This experiment demonstrates that lubiprostone stimulates recovery of barrier function in ischemic intestinal tissues whereas the PEG laxative had deleterious effects on mucosal repair. These results suggest that,unlike osmotic laxatives,lubiprostone stimulates repair of the injured intestinal barrier.	Adam J Moeser Prashant K Nighot Birgit Roerig Ryuji Ueno Anthony T Blikslager	2008	World Journal of Gastroenterology2008，14，39：	2
2	Photochemistry on nonreactive and reactive (semiconductor) surfaces 显示文摘	Prashant V K	1993	Chem Rev1993，93，：	1
3	Streptomycin induced protein expression analysis in Mycobacteriurn tuberculosis by two-dimensional gel electrophoresis & mass spectrometry显示文摘	Prashant S Bhavnesh K Neelja S	2010	Indian Journal of Medical Research2010，132，：	1
4	J Phys Chem B 显示文摘	Taku H Shunichi F Prashant V K	2006	110(50): 254772006，110，25：	1
5	A 28-W portable direct borohydride-hydrogen peroxide fuel-cell stack 显示文摘	RAMAN R K PRASHANT S K SHUKLA A K	2006	Journal of Power Sources2006，162，：	1
6	Application of LIBS in detection of antihyperglycemic trace elements in Momordica charantia 显示文摘	Nilesh K R Prashant K R Shiwani P	2009	Food Biophysics2009，4，3：	1
7	Graphene-based nanoassemblies for en- ergy conversion显示文摘	PRASHANT V K	2011	J Phys Chem Lett2011，2，：	1
8	Distributed mechanisms for quality of service in wireless LANs显示文摘	WASAN P A PRASHANT K SUJATA B	2003	IEEE Wireless Communications Magazine2003，10，3：	1
9	Effect of working gap and components by a magnetic field assisted finishing process显示文摘	Jain V K Prashant Kumar Behera P K eL al	2004	Pre- cision Engineering2004，28，：	1
10	Barium hexaaluminate nanowhiskers synthesized by novel sol-gel process in reverse micellar media显示文摘	Prashant K Sahu Kulkarni B D Khomane R B	2003	Chemistry Communications2003，15，：	1
11	Alliance capability,stock market response,and long-term alliance success:the role of the alliance function显示文摘	Prashant K Dyer J H Singh H	2002	Strategic Management Journal2002，，23：	1
12	Photophysical,photochemical and photocatalytic aspects of metal nanoparticles显示文摘	PRASHANT V K	2002	J Phys Chem B2002，106，：	1
13	Asparagus racemosus Willd (Liliaceae) ameliorates early diabetic nephropathy in STZ induced diabetic rats显示文摘	Rahul S Abhay S Prashant K	2012	Indian Journal of Experimental Biology2012，50，7：	1
14	Capped semiconductor colloids:synthesis and photoelectrochemical behavior of TiO2-capped SnO2nanocrystallites 显示文摘	IDRISS B PRASHANT V K	1995	J Phys Chem1995，99，：	1
15	Learning and proprietary assets in strategic alliances: Building relational capital 显示文摘	Prashant K Harbir S Howard P	2000	Strategic Management Journal2000，21，3：	1
16	Development of a PCR based assay for rapid and reliable identification of pathogenic Fusarium显示文摘	Prashant K M Roland T V Alastair C	2003	FEMS Microbiology Letters2003，218，2：	1
17	Content-based image retrieval using moments of local ternary pattern 显示文摘	PRASHANT S NGUYEN T B ASHISH K	2014	Mobile Networks and Applications2014，19，5：	1
18	Size-dependent electron injection from excited CdSe quantum dots into TiO2 nanoparticles 显示文摘	Istvan R Masaru K Prashant V	2007	J Am Chem Soc2007，129，14：	1
19	Enhanced Rates of Photocatalytic Degradation of a Textile Azo Dye Using SnO2/TiO2 Coupled Semiconductor Thin Films显示文摘	Vinodgopal K Kamat Prashant V	1995	Environmental Science & Technology1995，29，3：	1
20	Emergence of a nephropathogenic avian infectious bronchitis virus with a novel genotypein India 显示文摘	Agadeesh B lallikaljun S G Prashant K N	2005	Journal of Clinical Microbiology2005，43，2：	1

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