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| 1 | Dendritic cell deficiencies persist seven months after SARS-CoV-2 infection显示文摘Severe Acute Respiratory Syndrome Coronavirus(SARS-CoV)-2 infection induces an exacerbated inflammation driven by innate immunity components.Dendritic cells(DCs)play a key role in the defense against viral infections,for instance plasmacytoid DCs(pDCs),have the capacity to produce vast amounts of interferon-alpha(IFN-α).In COVID-19 there is a deficit in DC numbers and IFN-αproduction,which has been associated with disease severity.In this work,we described that in addition to the DC deficiency,several DC activation and homing markers were altered in acute COVID-19 patients,which were associated with multiple inflammatory markers.Remarkably,previously hospitalized and nonhospitalized patients remained with decreased numbers of CD1c+myeloid DCs and pDCs seven months after SARS-CoV-2 infection.Moreover,the expression of DC markers such as CD86 and CD4 were only restored in previously nonhospitalized patients,while no restoration of integrinβ7 and indoleamine 2,3-dyoxigenase(IDO)levels were observed.These findings contribute to a better understanding of the immunological sequelae of COVID-19. | Alberto Pérez-Gómez Joana Vitallé Carmen Gasca-Capote Alicia Gutierrez-Valencia María Trujillo-Rodriguez Ana Serna-Gallego Esperanza Muñoz-Muela María de los Reyes Jiménez-Leon Mohamed Rafii-El-Idrissi Benhnia Inmaculada Rivas-Jeremias Cesar Sotomayor Cristina Roca-Oporto Nuria Espinosa Carmen Infante-Domínguez Juan Carlos Crespo-Rivas Alberto Fernández-Villar Alexandre Pérez-González Luis Fernando López-Cortés Eva Poveda Ezequiel Ruiz-Mateos JoséMiguel Cisneros Sonsoles Salto-Alejandre Judith Berastegui-Cabrera Pedro Camacho-Martínez Carmen Infante-Domínguez Marta Carretero-Ledesma Juan Carlos Crespo-Rivas Eduardo Márquez JoséManuel Lomas Claudio Bueno Rosario Amaya JoséAntonio Lepe Jerónimo Pachón Elisa Cordero Javier Sánchez-Céspedes Manuela Aguilar-Guisado Almudena Aguilera Clara Aguilera Teresa Aldabo-Pallas Verónica Alfaro-Lara Cristina Amodeo Javier Ampuero María Dolores Avilés Maribel Asensio Bosco Barón-Franco Lydia Barrera-Pulido Rafael Bellido-Alba Máximo Bernabeu-Wittel Candela Caballero-Eraso Macarena Cabrera Enrique Calderón Jesús Carbajal-Guerrero Manuela Cid-Cumplido Yael Corcia-Palomo Juan Delgado Antonio Domínguez-Petit Alejandro Deniz Reginal Dusseck-Brutus Ana Escoresca-Ortega Fátima Espinosa Nuria Espinosa Michelle Espinoza Carmen Ferrándiz-Millón Marta Ferrer Teresa Ferrer Ignacio Gallego-Texeira Rosa Gámez-Mancera Emilio García Horacio García-Delgado Manuel García-Gutiérrez María Luisa Gascón-Castillo Aurora González-Estrada Demetrio González Carmen Gómez-González Rocío González-León Carmen Grande-Cabrerizo Sonia Gutiérrez Carlos Hernández-Quiles Inmaculada Concepción Herrera-Melero Marta Herrero-Romero Luis Jara Carlos Jiménez-Juan Silvia Jiménez-Jorge Mercedes Jiménez-Sánchez Julia Lanseros-Tenllado Carmina López Isabel López Álvaro López-Barrios Luis F.López-Cortés Rafael Luque-Márquez Daniel Macías-García Guillermo Martín-Gutiérrez Luis Martín-Villén JoséMolina Aurora Morillo María Dolores Navarro-Amuedo Dolores Nieto-Martín Francisco Ortega María Paniagua-García Amelia Peña-Rodríguez Esther Pérez Manuel Poyato Julia Praena-Segovia Rafaela Ríos Cristina Roca-Oporto Jesús F.Rodríguez María Jesús Rodríguez-Hernández Santiago Rodríguez-Suárez Ángel Rodríguez-Villodres Nieves Romero-Rodríguez Ricardo Ruiz Zida Ruiz de Azua Celia Salamanca Sonia Sánchez Víctor Manuel Sánchez-Montagut César Sotomayor Alejandro Suárez Benjumea Javier Toral | 2021 | Cellular & Molecular Immunology2021，18，9： | 2 |
| 2 | 显示文摘 | Jimenez de Haro M C Perez-Rodriguez J L Poyato J | 2005 | Applied Clay Science2005，30，1： | 1 |
| 3 | Effect of Na^+ and NH4^+ cations on microstructure changes of natual vermiculite during heat treatment显示文摘 | J Poyato | 2002 | Journal of Thermal Analysis and Calorimetry2002，67，： | 1 |
| 4 | Spark plasma sintering of Ti x Ta 1? x C 0.5 N 0.5 -based cermets: Effects of processing conditions on chemistry, microstructure and mechanical properties显示文摘 | José M. Córdoba Ernesto Chicardi Rosalía Poyato Francisco J. Gotor Valentina Medri Stefano Guicciardi Cesare Melandri | 2013 | Chemical Engineering Journal2013，，： | 1 |
| 5 | Referencias intertextuales de Carne Trémula显示文摘 | Pedro Poyato | 2012 | Zer nǘmero2012，，： | 1 |
| 6 | Single-wall carbon nanotubes at ceramic grain boundaries显示文摘 | Vasiliev A L Poyato R Padture N P | 2007 | Scripta Materialia2007，56，6： | 1 |
| 7 | Complete characterization of a quantum process:the two-bit quantum gate显示文摘 | POYATOS J F CIRAC J I ZOLLER P | 1997 | Physical Review Letters1997，78，2： | 1 |
| 8 | Rheic Ocean ophiolitic remnants in southern Ibeda questioned by SHRIMP U-Pb zircon ages on the Beja-Acebuches amphibolites显示文摘 | Azor A Rubatto D Simancas J.F González Lodeiro F Martínez Poyatos D Martín Parra L.M Matas J | | 0，，： | 1 |
| 9 | Effect of the concentration of suspended solids on the enzymatic activities and biodiversity of a submerged membrane bioreactor for aerobic treatment of domestic wastewater显示文摘 | M Molina-Munoz J M Poyatos R Vilchez | 2007 | Appl MicrobiolBiotechnol2007，73，6： | 1 |
| 10 | Automatic generation of consensus ground truth for the comparison of edge detection techniques显示文摘 | Garcia N L F Poyato A C Carnicer R M | 2008 | Image and Vision Computing2008，26，4： | 1 |
| 11 | Advanced oxidation processes for wastewater treatment : state of the art 显示文摘 | Poyatos J M Munio M M Almecija M C | 2010 | Water Air and Soil Pollution2010，205，1234： | 1 |
| 12 | Variation in the radial patterns of sap flux density in pubescent oak(Quercus pubescens)and its implications for tree and stand transpiration measurements显示文摘 | Poyatos R ∨Cermák J Llorens P | 2007 | Tree Physiology2007，27，4： | 1 |
| 13 | Single-wall carbon nanotubes at ceramic grain boundaries 显示文摘 | Vasiliev A L Poyato R Padture N P | 2007 | Scripta Materialia2007，56，： | 1 |
| 14 | Diagnosis of Sturge - Weber syndrome: comparison of the efficacry of CT and MR imaging in 14 cases 显示文摘 | Marti BL Menor F Poyatos C | 1992 | AJR1992，158，4： | 1 |
| 15 | Complexes with poly(N-heterocyclic carbene) ligands:structural features and catalytic applications显示文摘 | POYATOS M MATA J A PERIS E | | 0，，08： | 1 |
| 16 | Diagnosis of Sturge-Weber Syndrome:Comparison of the Efficacy of CT and MR Imaging in14 Casesl显示文摘 | Marti BL Menor F Poyatos C | 1992 | AJR1992，158，4： | 1 |
| 17 | Clinical Aspects and Prognostic Factors in Elderly Patients Hospitalised for Community-Acquired Pneumonia显示文摘 | M. A. García-Ordó?ez J. M. García-Jiménez F. Páez F. álvarez B. Poyato M. Franquelo J. D. Colmenero C. Juárez | 2001 | European Journal of Clinical Microbiology and Infectious Diseases2001，，1： | 1 |
| 18 | A new look at water transport regulation in plants显示文摘 | Martinez-Vilaha J Poyatos R Aguad6 D | 2014 | New Phytologist2014，204，1： | 1 |
| 19 | Variation in the radial patterns of sap flux density in pubescent oak ( Quercus pubescens) and its implications for tree and stand transpiration measurements显示文摘 | Poyatos R Cermdk J Llorens P | 2007 | Tree physiology2007，27，4： | 1 |
| 20 | Comparative analysis of the bacterial diversity in a lab-scale moving bed biofilm reactor (MBBR) applied to treat urban wastewater under different operational conditions 显示文摘 | CALDERON K MARTfN-PASCUAL J POYATOS J M | 2012 | Bioresour Teehnol2012，10，121： | 1 |
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