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| 1 | Solution processed MoS2-PVA composite for subbandgap mode-locking of a wideband tunable ultrafast Er:fiber laser显示文摘我们制作自立的很少层铝二硫化物(瞬间 < 潜水艇 class= “ a-plus-plus ” > 由化学上太古的 MoS2 晶体和使用的液体阶段脱落合成的 2 )-polymer 这表明一条宽带悦耳, ultrafast 锁模式的纤维激光。稳定,微微秒脉搏,从 1,535 nm 悦耳到 1,565 nm,被产生,相应于在瞬间下面的光子精力 < 潜水艇 class= “ a-plus-plus ” > 2 材料 bandgap。这些结果贡献学习转变金属 dichalcogenides 的非线性的光性质的工作的成长身体为 ultrafast photonic 应用的现在的新机会。 | Meng Zhang Richard C. T. Howe Robert I. Woodward Edmund J. R. Kelleher Felice Torrisi Guohua Hu Sergei V. Popov J. Roy Taylor Tawfique Hasan | 2015 | Nano Research2015，8，5： | 13 |
| 2 | Local Proinflammatory Effects of Repeated Skin Exposure to Warfarin, An Anticoagulant Rodenticide in Rats显示文摘Objective: To evaluate the effects of epicutaneous application of anticoagulant warfarin, by examining the presence of tissue injury and immune/inflammatory activity in exposed skin. Methods: Rats were exposed to warfarin by applying 10 μg of warfarin‐sodium to 10‐12 cm 2 skin (range 0.8‐1 μg per 1 cm 2 ) for 3 consecutive days. Tissue injury was evaluated by lipid peroxidation, histomorphological changes and signs of reparative activity in skin. T cell infiltration and selected aspects of epidermal cell activity were examined as indicators of immune/inflammatory skin response to warfarin application. Results: Repeated warfarin application exerted no effect on skin metabolic viability, but resulted in tissue injury (increased malondialdehyde, MDA, production, evident histo‐morphological changes in epidermis and dermis depicting cell injury and death). Increased numbers of proliferating cell nuclear antigen (PCNA + ) cells indicated reparative processes in injured skin. Infiltration of CD3 + cells (T lymphocytes) along with the increased production of tumor necrosis factor‐α (TNF‐α) by epidermal cells from warfarin‐treated skin and their co‐stimulatory effect in an in vitro T‐cell activation assay demonstrated immunomodulatory effects of epicutaneous warfarin. Conclusion: Presented data have documented tissue damage associated with immune/ inflammatory activity in skin exposed to warfarin. Observed effects are relevant to immunotoxic potential of this anticoagulant in settings of external exposure. | Aleksandra POPOV Ivana MIRKOV Lidija ZOLOTAREVSKI Milena JOVIC Sandra BELIJ Dragan KATARANOVSKI Milena KATARANOVSKI | 2011 | Biomedical and Environmental Sciences2011，24，2： | 13 |
| 3 | Role of the receptor for advanced glycation end products in hepatic fibrosis显示文摘AIM:To study the role of advanced glycation end products(AGE)and their specifi c receptor(RAGE)in the pathogenesis of liver fi brogenesis.METHODS:In vitro RAGE expression and extracellular matrix-related gene expression in both rat and human hepatic stellate cells(HSC)were measured after stimulation with the two RAGE ligands,advanced glycation end product-bovine serum albumin(AGE-BSA)and Nε-(carboxymethyl)lysine(CML)-BSA,or with tumor necrosis factor-α(TNF-α).In vivo RAGE expression was examined in models of hepatic fi brosis induced by bile duct ligation or thioacetamide.The effects of AGE-BSA and CML-BSA on HSC proliferation,signal transduction and profi brogenic gene expression were studied in vitro.RESULTS:In hepatic fibrosis,RAGE expression was enhanced in activated HSC,and also in endothelial cells,inflammatory cells and activated bile duct epithelia.HSC expressed RAGE which was upregulated after stimulation with AGE-BSA,CML-BSA,and TNF-α.RAGE stimulation with AGE-BSA and CML-BSA did not alter HSC proliferation,apoptosis,fibrogenic signal transduction and fibrosis-or fibrolysis-related gene expression,except for marginal upregulation of procollagen α1(Ⅰ)mRNA by AGE-BSA.CONCLUSION:Despite upregulation of RAGE in activated HSC,RAGE stimulation by AGE does not alter their fibrogenic activation.Therefore,RAGE does not contribute directly to hepatic fibrogenesis. | Christina Lohwasser Daniel Neureiter Yury Popov Michael Bauer Detlef Schuppan | 2009 | World Journal of Gastroenterology2009，15，46： | 13 |
| 4 | Preventive effect of a pectic polysaccharide of the common cranberry Vaccinium oxycoccos L. on acetic acid-induced colitis in mice显示文摘AIM: To study isolation and chemical characterization of pectin derived from the common cranberry Vaccinium oxycoccos L. (oxycoccusan OP) and the testing of its preventive effect on experimental colitis.METHODS: Mice were administrated orally with OP two days prior to a rectal injection of 5% acetic acid and examined for colonic damage 24 h later. Colonic inflammation was characterized by macroscopical injury and enhanced levels of myeloperoxidase activity measured spectrophotometrically with o-phenylene diamine as the substrate. The mucus contents of the colon were determined by the Alcian blue dye binding method. Vascular permeability was estimated using 4% Evans blue passage after i.p. injection of 0.05 mol/L acetic acid. RESULTS: In the mice treated with OP, colonic macroscopic scores (1.1 ± 0.4 vs 2.7, P < 0.01) and the total square area of damage (10 ± 2 vs 21 ± 7, P < 0.01) were significantly reduced when compared with the vehicle-treated colitis group. OP was shown to decrease the tissue myeloperoxidase activity in colons (42 ± 11 vs 112 ± 40, P < 0.01) and enhance the amount of mucus of colitis mice (0.9 ± 0.1 vs 0.4 ± 0.1, P < 0.01). The level of colonic malondialdehyde was noted to decrease in OP-pretreated mice (3.6 ± 0.7 vs 5.1 ± 0.8, P < 0.01). OP was found to decrease the inflammatory status of mice as was determined by reduction of vascular permeability (161 ± 34 vs 241 ± 21, P < 0.01). Adhesionof peritoneal neutrophils and macrophages was also shown to decrease after administration of OP (141 ± 50 vs 235 ± 37, P < 0.05).CONCLUSION: Thus, a preventive effect of pectin from the common cranberry, namely oxycoccusan OP, on acetic acid-induced colitis in mice was detected. A reduction of neutrophil infiltration and antioxidant action may be implicated in the protective effect of oxycoccusan. | Sergey V Popov Pavel A Markov Ida R Nikitina Sergey Petrishev Vasily Smirnov Yury S Ovodov | 2006 | World Journal of Gastroenterology2006，12，41： | 9 |
| 5 | Treatment of rectal prolapse in children with cow milk injection sclerotherapy:30-year experience显示文摘AIM:To evaluate the role and our experience of injecti-on sclerotherapy with cow milk in the treatment of rectal prolapse in children. METHODS:In the last 30 years (1976-2006) we made 100 injections of sclerotherapy with cow milk in 86 chil-dren. In this study we included children who failed to respond to conservative treatment and we perform ope-rative treatment. RESULTS:In our study we included 86 children and in all of the patients we perform cow milk injection sclerot-herapy. In 95.3% (82 children) of patients sclerotherapy was successful. In 4 (4.7%) patients we had recurrent rectal prolapse where we performed operative treatment. Below 4 years we had 62 children (72%) and 24 older children (28%). In children who needed operative trea-tment we performed Thiersch operation and without any complications. CONCLUSION:Injection sclerotherapy with cow milk for treatment rectal prolapse in children is a simple and effective treatment for rectal prolapse with minimal com-plications. | Mirko Zganjer Ante Cizmic Irenej Cigit Bozidar Zupancic Igor Bumci Ljiljana Popovic Antun Kljenak | 2008 | World Journal of Gastroenterology2008，14，5： | 8 |
| 6 | Correlation of microstructure and magnetic properties in Sm(Co_(bal)Fe_(0.1)Cu_(0.1)Zr_(0.033))_(6.93) magnets solution-treated at different temperatures显示文摘The correlation of microstructure and magnetic properties in Sm(Co_(bal)Fe_(0.1)Cu_(0.1)Zr_(0.033))_(6.93) magnets solution-treated at different temperatures was systematically investigated. It is found that the magnets solution-treated at 1219℃ possess a single 1:7 H phase, exhibiting the homogeneous cellular structure during further aging treatment, leading to the optimum magnetic properties. However, for the magnets solution-treated at 1211 and 1223℃,2:17 H or 1:5 H secondary phase will also form besides 1:7 H main phase, which cannot transform into cellular structure,thus deteriorating the magnetic properties greatly. The irreversible magnetization investigations with recoil loops also propose a non-uniform pinning in the magnets induced by the secondary precipitates. At proper solution temperature, Zr is supposed to occupy the Fe-Fe dumbbell sites in the form of Zr-vacancy pairs, leading to the minimum c/a ratio and thus stabilizing the 1:7 H phase. Finally,Sm(Co_(bal)Fe_(0.1)Cu_(0.1)Zr_(0.033))_(6.93) magnets with the maximum energy product and intrinsic coercivity at 550℃ up to 60.73 kJ·m^(-3) and 553.88 kA·m^(-1) were prepared by powder metallurgy method. | Cheng Xu Hui Wang Tian-Li Zhang Alexander Popov Raghavan Gopalan Cheng-Bao Jiang | 2019 | Rare Metals2019，38，1： | 6 |
| 7 | The pathologic relevance of metabolic criteria in patients with biopsy-proven nonalcoholic fatty liver disease and metabolic dysfunction associated fatty liver disease:A multicenter cross-sectional study in China显示文摘Background:This study aimed to assess the association between metabolic syndrome(Met S)and severity of nonalcoholic fatty liver disease(NAFLD),and to discuss the pathological relevance of the diagnostic criteria in metabolic(dysfunction)associated fatty liver disease(MAFLD).Methods:This was a multicenter,cross-sectional study.Patients with NAFLD confirmed by liver biopsy were enrolled between July 2016 and December 2018 from 14 centers across the mainland of China.Anthropometric and metabolic parameters were collected to assess the pathological relevance.Results:Of 246 enrolled patients with NAFLD,150(61.0%)had the comorbidity of Met S.With the increase of metabolic components,the proportions of nonalcoholic steatohepatitis(NASH)and significant fibrosis were notably increased.The comorbid three metabolic components significantly increased the proportion of NASH,and further increase of metabolic components did not increase the proportion of NASH.However,the increase of metabolic components was parallel to the increase of the proportion of liver fibrosis.Among the 246 patients,239(97.2%)met the diagnostic criteria of MAFLD.Although non-MAFLD patients had less NASH,they present with similar proportion of significant fibrosis and cirrhosis.In the diagnostic criteria of MAFLD,BMI≥23 kg/m2 was related to NASH(Mantel-Haenszel Common Estimate OR:2.975;95%CI:1.037–8.538;P=0.043),and T2 DM was related to significant fibrosis(Mantel-Haenszel Common Estimate OR:2.531;95%CI:1.388–4.613;P=0.002).The homeostasis model assessment of insulin resistance(HOMA-IR)≥2.5 was the most significant factor for NASH(OR:4.100;95%CI:1.772–9.487;P=0.001)and significant factor for liver fibrosis(OR:2.947;95%CI:1.398–6.210;P=0.004)after the adjustments of the BMI and diabetes.Conclusions:Metabolic dysregulations are important risk factors in NAFLD progression.The insulin resistance status may play a predominant role in the progression in MAFLD patients. | Rui-Xu Yang Zheng-Sheng Zou Bi-Hui Zhong Hong Deng Fang-Ping He Jun-Ping Shi Cai-Yan Zhao Yu-Qiang Mi Yong-Jian Zhou Fu-Sheng Di Rui-Dan Zheng Qin Du Jia Shang Branko Popovic Jin Jun Chen Jian-Gao Fan | 2021 | Hepatobiliary & Pancreatic Diseases International2021，20，5： | 5 |
| 8 | Mechanism of diarrhea in microscopic colitis显示文摘AIM: To search the pathophysiological mechanism of diarrhea based on daily stool weights, fecal electrolytes,osmotic gap and pH.METHODS: Seventy-six patients were included: 51 with microscopic colitis (MC) [40 with lymphocytic colitis (LC);11 with collagenous colitis (CC)]; 7 with MC without diarrhea and 18 as a control group (CG). They collected stool for 3 d. Sodium and potassium concentration were determined by flame photometry and chloride concentration by titration method of Schales. Fecal osmotic gap was calculated from the difference of osmolarity of fecal fluid and double sum of sodium and potassium concentration.RESULTS: Fecal fluid sodium concentration was significantly increased in LC 58.11±5.38 mmol/L (P<0.01)and CC 54.14±8.42 mmol/L (P<0.05) than in CG 34.28±2.98 mmol/L. Potassium concentration in LC 74.65±5.29 mmol/L (P<0.01) and CC 75.53±8.78 mmol/L (P<0.05) was significantly less compared to CG 92.67±2.99 mmol/L.Chloride concentration in CC 36.07±7.29 mmol/L was significantly higher than in CG 24.11±2.05 mmol/L (P<0.05).Forty-four (86.7%) patients had a secretory diarrhea compared to fecal osmotic gap. Seven (13.3%) patients had osmotic diarrhea.CONCLUSION: Diarrhea in MC mostly belongs to the secretory type. The major pathophysiological mechanism in LC could be explained by a decrease of active sodium absorption. In CC, decreased Cl/HCO3 exchange rate and increased chloride secretion are coexistent pathways. | Marijana Protic Njegica Jojic Daniela Bojic Svetlana Milutinovic Dusanka Necic Bozidar Bojic Petar Svorcan Miodrag Krstic Obren Popovic | 2005 | World Journal of Gastroenterology2005，11，35： | 5 |
| 9 | 氧消耗和二氧化碳恢复期动力学对冠状动脉疾病严重性和结局的预测价值显示文摘血管重塑似乎只对高度缺血的患者有益。该研究调查了在心肺功能运动试验(eardiopulmonary exercisetest,CPET)恢复期中气体分析预测冠状动脉疾病(coronary artery disease,CAD)严重性和预后的价值。方法:研究者研究了40例白人患者(21.2%女性),平均年龄(63.5±7.6)岁,有显著冠状动脉损伤(≥50%)。 | 黄洁 叶鹏 Popovic D Martic D Djordjevic T Pesic V Guazzi M Myers J Mohebi R Arena R | 2017 | 中华高血压杂志2017，25，10： | 5 |
| 10 | TiN-Ti-DLC等多层复合膜的摩擦学性能研究显示文摘在一台УВНИПА 1型双激发源等离子弧薄膜沉积装置上制取TiN Ti DLC、及其含有软金属Cu或PTFE覆盖膜的多层复合涂层。摩擦磨损试验在一台球 盘滑动磨损试验机上进行。结果表明,以TiN和DLC膜为主体的多层复合涂层具有较高的摩擦学特性,过渡金属钛层、软金属和聚四氟乙烯覆盖层可以降低摩擦系数33%~50%,对磨擦表面磨损减少90%。 | 江晓红 陆小华 金元生 Rogachev A.V. Kazachenko V.P. Popov A.N. | 2003 | 南京工业大学学报(自然科学版)2003，25，2： | 4 |
| 11 | Pyrite Formation in Organic-rich Clay, Calcitic and Coal-Forming Environments显示文摘在与连续褐煤层轮流出现的混合沉积(在泥土,沙岩或页岩的煤碎片) 的一个中新世的淡水序列的黄铁矿形成过程的早 dlagenetic 特征被调查。基于丰富的矿物质,下列主要沉积环境被区分:illite-montmorillonitic (I-M ) , calcitic (Ct ) 和形成煤的环境(CL ) 。为这些 hydrogeochemically 不同的环境,黄铁矿形成上的限制因子的效果处理(硫酸盐和 Fe 的可获得性,有机物的数量和器官的硫的参予) 被相关分析估计。在在特别环境的这些限制因子的效果的重要差别被观察。这些差别被解释在报道进行不同氧化活动, Fe 复杂并且环境和许多吸着的氢指数的腐殖的物质独立的表面建筑群形成性质结盟活跃粘土矿物。有一个相对低的氢指数并且包含黄铁矿先锋上的腐殖的物质(H ) 的氧化活动是的粘土矿物(I-M-and CL 环境) 的 Inenvironments 极大地阻止了黄铁矿形成不管多么作为复杂形成的后果取决于反应 Fe 可获得性。在矛盾在有一个相对高的氢指数的环境,因为它是 calcitic, H 的氧化活动极大地被提高,因此氧化黄铁矿的硫先锋。有机物的氧化度可能也是 humicelectron 领受人的不同活动的后果。 | Gordana DEVI Petar PFENDT Branimir JOVANIEVI Zoran POPOVIC | 2006 | Acta Geologica Sinica(English Edition)2006，80，4： | 4 |
| 12 | Multiscale Modeling and Simulations of Flows in Naturally Fractured Karst Reservoirs显示文摘Modeling and numerical simulations of fractured,vuggy,porus media is a challenging problem which occurs frequently in reservoir engineering.The problem is especially relevant in flow simulations of karst reservoirs where vugs and caves are embedded in a porous rock and are connected via fracture networks at multiple scales.In this paper we propose a unified approach to this problem by using the StokesBrinkman equations at the fine scale.These equations are capable of representing porous media such as rock as well as free flow regions(fractures,vugs,caves)in a single system of equations.We then consider upscaling these equations to a coarser scale.The cell problems,needed to compute coarse-scale permeability of Representative Element of Volume(REV)are discussed.A mixed finite element method is then used to solve the Stokes-Brinkman equation at the fine scale for a number of flow problems,representative for different types of vuggy reservoirs.Upscaling is also performed by numerical solutions of Stokes-Brinkman cell problems in selected REVs.Both isolated vugs in porous matrix as well as vugs connected by fracture networks are analyzed by comparing fine-scale and coarse-scale flow fields.Several different types of fracture networks,representative of short-and long-range fractures are studied numerically.It is also shown that the Stokes-Brinkman equations can naturally be used to model additional physical effects pertaining to vugular media such as partial fracture with fill-in by some material and/or fluids with suspended solid particles. | Peter Popov Yalchin Efendiev Guan Qin | 2009 | Communications in Computational Physics2009，6，6： | 4 |
| 13 | Biochemical markers for non-invasive assessment of disease stage in patients with primary biliary cirrhosis显示文摘AIM: To evaluate different biochemical markers and their ratios in the assessment of primary biliary cirrhosis (PBC) stages. METHODS: This study included 112 patients with PBC who underwent a complete clinical investigation. We analyzed the correlation (Spearman's test) between ten biochemical markers and their ratios with different stages of PBC. The discriminative values were compared using areas under receiver operating characteristic (ROC) curves. RESULTS: The mean age of patients included in the study was 53.88 ± 10.59 years, including 104 females and 8 males. We found a statistically significant correlation between PBC stage and Aspartate aminotransferase (AST), Alanine aminotransferase (ALT) to platelet ratio (APRI), ALT/platelet count, AST/ALT, ALT/AST and ALT/Cholesterol ratios, with the values of Spearman's rho of 0.338, 0.476, 0.404, 0.356, 0.351 and 0.325, respectively. The best sensitivity and specificity was shown for AST/ALT, with an area under ROC of 0.660. CONCLUSION: Biochemical markers and their ratios do correlate with different sensitivity to and specificity of PBC disease stage. The use of biochemical markers and their ratios in clinical evaluation of PBC patients may reduce, but not eliminate, the need for liver biopsy. | Tamara Alempijevic Miodrag Krstic Rada Jesic Ivan Jovanovic Aleksandra Sokic Milutinovic Nada Kovacevic Slobodan Krstic Dragan Popovic | 2009 | World Journal of Gastroenterology2009，15，5： | 4 |
| 14 | 腐殖质生理活性及其与化学组成关系的研究进展显示文摘腐殖质(HS)是生物体外具备生物学活性的最稳定有机物形式之一。本文综述了HS的化学组成、结构特征和生理活性,依据HS化学组成、结构特征和生理活性的相互关系探讨了HS具有生理活性的内在机制。HS化学组成具有不确定性,超分子结构假设目前被普遍接受。HS通过促进根毛形成和侧根发育、激活质膜H+-ATP酶产生有利的电化学梯度以及自身酸性官能团的螯合作用等促进植物对矿质元素的吸收利用;HS具有类激素活性,植物根际促生细菌(PGPR)分泌物或HS自体组分吲哚-3-乙酸(IAA)能够激活细胞质膜H+-ATPase,HS还能够增加内源植物激素水平,促进植物生长发育;HS通过介导信使NO激活细胞质膜H+-ATPase,清除HS与细胞作用产生的活性氧(ROS),HS通过NO和抗氧化酶调节细胞内ROS稳态,介导根系发育和形态结构。本文还着重探讨了HS生理活性与化学组成的相关性,其中官能团—COOH和—OH活性位点的作用、醌基的电子传递,以及HS亲水疏水平衡与HS生理活性密切相关。未来HS研究工作的重点在于深入研究HS分子结构、明确具备生理活性的“共性结构原件”、阐明HS诱导胞内信号传导通路之间的交叉反馈机制、揭示HS对细胞内物质和能量代谢相关基因表达的调节机制。 | 宋鸽 POPOV Alexander Ivanovich 石峰 | 2021 | 农业资源与环境学报2021，38，4： | 4 |
| 15 | Fecal microbial transplant for the treatment of pediatric inflammatory bowel disease显示文摘The role of fecal microbial transplant(FMT) in the treatment of pediatric gastrointestinal disease has become increasingly popular among pediatric practitioners, patients, and parents. The success of FMT for the treatment of recurrent Clostridium difficile infection(RCDI) has bolstered interest in its potential application to other disease states, such as inflammatory bowel disease(IBD). FMT has particular interest in pediatrics, given the concerns of patients and parents about rates of adverse events with existing therapeutic options, and the greater cumulative medication burden associated with childhoodonset disease. Published literature on the use of FMT in pediatrics is sparse. Only 45 pediatric patients treated for RCDI have been reported, and only 27 pediatric patients with pediatric IBD. The pediatric microbiome may uniquely respond to microbial-based therapies. This review will provide a comprehensive overview of fecal microbial transplant and its potential role in the treatment of pediatric inflammatory bowel disease. We will discuss the microbiome in pediatric inflammatory bowel disease, existing adult and pediatric literature on the use of FMT in IBD treatment, and pediatric FMT trials that are currently recruiting patients. This review will also discuss features of the microbiome that may be associated with host response in fecal transplant, and potential challenges and opportunities for the future of FMT in pediatric IBD treatment. | Alice Yuxin Wang Jelena Popov Nikhil Pai | 2016 | World Journal of Gastroenterology2016，22，47： | 4 |
| 16 | 热处理对类金刚石碳薄膜力学和摩擦性能的影响显示文摘利用直流磁分离及脉冲阴极双激发源等离子弧薄膜沉积装置制备了含Ti底层和无Ti底层的类金刚石碳薄膜(DLC);采用纳米硬度计、原子力显微镜和X射线光电子能谱仪分析了薄膜的力学性能和结构;采用УСК-1型球-盘滑动摩擦磨损试验机考察了薄膜的摩擦性能.结果表明,同无Ti底层的DLC薄膜相比,含Ti底层的DLC薄膜的硬度和弹性模量较低;含Ti底层的DLC薄膜经真空400℃退火后表面层中存在TiO2,内部存在TiC;而无Ti底层的DLC薄膜经真空500℃退火处理后硬度、弹性模量和表面形貌几乎保持不变;无Ti底层的DLC薄膜经空气中500℃退火后摩擦系数明显降低,这是由于DLC薄膜在空气中热处理时更易发生石墨化所致. | 江晓红 金元生 KAZACHENKO V P POPOV A N ROGACHEV A V | 2004 | 摩擦学学报2004，24，3： | 4 |
| 17 | Subchronic Oral Cadmium Exposure Exerts both Stimulatory and Suppressive Effects on Pulmonary Inflammation/Immune Reactivity in Rats显示文摘Objective The aim of this study is to investigate the effects of oral cadmium(Cd) ingestion on the pulmonary immune response. Methods Determination of Cd content in lungs and histopathological evaluation of the tissue was performed in rats following 30-day oral Cd administration(5 and 50 mg/L). Antioxidant enzyme defense(superoxide dismutase and catalase), cell infiltration, and production of tumor necrosis factor(TNF) and interferon(IFN)-γ, as well as the activity of myeloperoxidase(MPO), nitric oxide(NO), and various cytokines [interleukin(IL)-1β, IL-6, IL-10, and IL-17] were investigated. Results Cd caused tissue damage and cell infiltration in the lungs, and this damage was more pronounced at higher doses. Cd deposition resulted in lung inflammation characterized by a dose-dependent IL-1β increase in lung homogenates, increased TNF levels at both doses, and IL-6 stimulation at low doses with inhibition observed at higher doses. Cd exerted differential effects on lung leukocytes isolated by enzyme digestion, and these effects were characterized by a lack of change in the production of reactive oxygen and nitrogen species, an inhibition of IL-1β and TNF, and stimulation of MPO and IFN-γ. The higher capacity of Cd-exposed lung cells to respond to the opportunistic pathogen Staphylococcus epidermidis was demonstrated in vitro. Conclusion The potential of ingested Cd to exert both proinflammatory and immunosuppressive effects on pulmonary tissue inflammation and immune reactivity highlights the complex immunomodulatory actions of this metal. | KULAS Jelena NINKOV Marina TUCOVIC Dina POPOV Aleksandrov Aleksandra UKROPINA Mirela CAKIC MILOSEVIC Maja MUTIC Jelena KATARANOVSKI Milena MIKROV Ivana | 2019 | Biomedical and Environmental Sciences2019，32，7： | 4 |
| 18 | Tricaine methane‐sulfonate (MS‐222) application in fish anaesthesia显示文摘 | N. Topic Popovic I. Strunjak‐Perovic R. Coz‐Rakovac J. Barisic M. Jadan A. Persin Berakovic R. Sauerborn Klobucar | 2012 | Journal of Applied Ichthyology2012，，4： | 3 |
| 19 | Hedgehog signaling regulates epithelial-mesenchymal transition during biliary fibrosis in rodents and humans显示文摘 | Omenetti Alessia Porrello Alessandro Jung Youngmi Yang Liu Popov Yury Choi Steve S Witek Rafal P Alpini Gianfranco Venter Juliet Vandongen Hendrika M Syn Wing-Kin Baroni Gianluca Svegliati Benedetti Antonio Schuppan Detlef Diehl Anna Mae | 2008 | Journal of Clinical Investigation2008，，10： | 3 |
| 20 | Unique Marine Olenekian-Anisian Boundary Section from South Primorye, Russian Far East显示文摘To show paleontological characteristics of the Olenekian-Anisian boundary beds in the Russian Far East, a review of new data on the Upper Olenekian and Lower Anisian biostratigraphy of South Primorye is given on the basis of five sections: Golyi Cape, Petrovka River, Zhitkov Peninsula, Tchernyschew Bay and Atlasov Cape, using new ammonoid, brachiopod and conodont findings. The most representative ammonoid assemblage at the base of the Anisian was discovered in the Ussuriphyllites amurensis Zone (10.6 m thick) of the Atlasov Cape Section: Parasageceras sp. nov., Prionitidae gen. et sp. nov., Ussuriphyllites amurensis (Kiparisova) (dominant), Megaphyllites atlasoviensis Zakharov, Leiophyllites praematurus Kiparisova, Leiophyllites sp., Ussurites sp., Paradanubites sp. indet., Paracrochordiceras sp. nov., Prohungarites popowi Kiparisova, Arctohungarites primoriensis Zakharov, A. solimani (Toula), Salterites sp. indet. (gigantic shell), and Tropigastrites sublachontanus Zakharov. Conodonts Neospathodus cf. homeri (Bender) were found in the lower part of the Ussuriphyllites amurensis Zone of the Atlasov Cape. The Atlasov Cape seems to be one of the very promising sections of the Russian Far East for detailed investigation of the Olenekian-Anisian boundary. | Yuri D Zakharov Alexander M Popov Galina I Buryi | 2005 | Journal of China University of Geosciences2005，16，3： | 3 |
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