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| 1 | Isoplot R: A free and open toolbox for geochronology显示文摘This paper reviews the basic principles of radiometric geochronology as implemented in a new software package called Isoplot R, which was designed to be free, flexible and future-proof. Isoplot R is free because it is written in non-proprietary languages(R, Javascript and HTML) and is released under the GPL license. The program is flexible because its graphical user interface(GUI) is separated from the command line functionality, and because its code is completely open for inspection and modification. To increase future-proofness, the software is built on free and platform-independent foundations that adhere to international standards, have existed for several decades, and continue to grow in popularity.Isoplot R currently includes functions for U-Pb, Pb-Pb,40 Ar/39 Ar, Rb-Sr, Sm-Nd, Lu-Hf, Re-Os, U-Th-He,fission track and U-series disequilibrium dating. It implements isochron regression in two and three dimensions, visualises multi-aliquot datasets as cumulative age distributions, kernel density estimates and radial plots, and calculates weighted mean ages using a modified Chauvenet outlier detection criterion that accounts for the analytical uncertainties in heteroscedastic datasets. Overdispersion of geochronological data with respect to these analytical uncertainties can be attributed to either a proportional underestimation of the analytical uncertainties, or to an additive geological scatter term.Isoplot R keeps track of error correlations of the isotopic ratio measurements within aliquots of the same samples. It uses a statistical framework that will allow it to handle error correlations between aliquots in the future. Other ongoing developments include the implementation of alternative user interfaces and the integration of Isoplot R with other data reduction software. | Pieter Vermeesch | 2018 | Geoscience Frontiers2018，9，5： | 56 |
| 2 | Association of smoking, alcohol drinking and dietary factors with esophageal cancer in high- and low-risk areas of Jiangsu Province, China显示文摘瞄准:到环境的 main 和在食道的癌症(EC ) 说明地区性的差别的生活方式因素在江苏省的低风险、高风险的区域冒的风险的学习,中国。方法:自从 2003,基于人口的盒子控制研究同时被进行了在低风险(Ganyu 县) 并且高风险(Dafeng 县) 江苏省的区域,中国。使用相同协议和 pre-tested 标准化了问询表,跟随写的知情同意,合格题目被询问他们 EC 的潜在的决定因素的详细信息包括人口统计的信息,社会经济的地位,生活条件,疾病历史,家庭癌症历史,吸烟,酒精喝酒,饮食的习惯,频率,食物摄取的数量,等等。有最大的可能性评价的有条件的逻辑回归被用来获得机会比率(或) 并且 95 % 信心间隔(95% CI ) ,在为潜力的调整以后,反对失败。结果:在进行中的学习的初步的分析,我们招募了在 Ganyu 的在 Dafeng 的 291 个盒子和 240 个盒子和控制分别地。在低风险、高风险的区域, EC 相反地与社会经济的地位被联系,例如教育的水平,经过经济地位和身体团索引。然而,这疾病在有癌症的家庭历史或在过去的 10 年里遇到了不幸的那些之中是更经常的。EC 在吸烟者,白酒喝酒者和快食客之中也是更经常的。而且,有在吸烟,酒精喝酒和尽管有在低风险、高风险的区域的这些风险因素的类似的流行的 EC 风险之间的协会的一个地理变化。吸烟并且吸烟的剂量反应关系联系了变量,例如首先吸烟,持续时间和数量的年龄在高风险的区域仅仅是明显的。相反,在 EC 上喝的酒精的效果上的一种剂量反应关系仅仅在低风险的区域被观察。结论:环境风险因素,可能和基因因素和基因环境的相互作用是为在江苏省的这个高风险的坡度的主要原因,中国。 | Ming Wu Jin-Kou Zhao Xiao-Shu Hu Pei-Hua Wang Yu Qin Yin-Chang Lu Jie Yang Ai-Min Liu De-Lin Wu Zuo-Feng Zhang Kok J Frans Pieter van't Veer | 2006 | World Journal of Gastroenterology2006，12，11： | 18 |
| 3 | “猪地方性肺炎及其防治控制”专栏二:有关猪肺炎支原体感染诊断方法和流行病学的最新观点显示文摘猪肺炎支原体是猪地方性肺炎(Enzoodc Pneumonia,EP)的主要病原体,本病是一种主要影响肥育猪的慢性呼吸道疾病。尽管人们在控制猪肺炎支原体感染及其带来的不利影响上花费了大量的精力,但是猪地方性肺炎仍继续给全球养猪生产造成重大的经济损失。猪肺炎支原体通常是通过引进亚临床型感染的动物而侵入猪群的,或通过短距离的空气传播发生感染,但后一种情况较少。一旦侵入猪群,猪肺炎支原体可通过与受感染的母猪直接接触而将病原体传给后代或在同圈猪只之间进行传播。用于诊断猪肺炎支原体感染的“黄金标准”技术——细菌学培养非常费劲,通常很少使用。酶联免疫吸附试验和聚合酶链式反应检测方法以及以屠宰场监测或田间剖解为形式的死后检查,是用于调查猪肺炎支原体是否参与了猪呼吸道疾病的最常用技术。这些技术已被用来监测受猪地方性肺炎影响的猪群猪肺炎支原体的临床型和亚临床型感染猪群、免疫猪群或非免疫猪群以及处于不同的生产条件和管理奈件下的猪群的发生情况。猪场水平上的猪地方性肺炎临床过程差异以及猪肺炎支原体疫苗接种效果的差异表明,猪肺炎支原体的不同田间分离株的传播和毒力特性存在差异。本文综述了猪肺炎支原体感染的流行病学最新知识,包括其传播、感染和血清转化动力学,并且还比较了用来监测猪地方性肺炎的各种流行病学方法。 | Marina Sibila Maria Pieters Thomas Molitor Dominiek Maes Freddy Haesebmuck Joaquim Segal e s 沈权(译) 邵嘉佳(校) | 2009 | 国外畜牧学(猪与禽)2009，，3： | 16 |
| 4 | Study of atmospheric CO2 and CH4 at Longfengshan WMO/GAW regional station: The variations, trends, influence of local sources/sinks, and transport显示文摘Atmospheric CO_2 and CH_4 have been continuously measured since 2009 at Longfengshan WMO/GAW station(LFS) in China. Variations of the mole fractions, influence of long-distance transport, effects of local sources/sinks and the characteristics of synoptic scale variations have been studied based on the records from 2009 to 2013. Both the CO_2 and CH_4 mole fractions display increasing trends in the last five years, with growth rates of 3.1±0.02 ppm yr.1 for CO_2 and 8±0.04 ppb yr.1(standard error, 1-σ)for CH_4. In summer, the regional CO_2 mole fractions are apparently lower than the Marine Boundary Layer reference, with the lowest value of.13.6±0.7 ppm in July, while the CH_4 values are higher than the MBL reference, with the maximum of 139±6 ppb.From 9 to 17(Local time, LT) in summer, the atmospheric CO_2 mole fractions at 10 m a.g.l. are always lower than at 80 m, with a mean difference of.1.1±0.2 ppm, indicating that the flask sampling approach deployed may underestimate the background mole fractions in summer. In winter, anthropogenic emissions dominate the regional CO_2 and CH_4 mole fractions. Cluster analysis of backward trajectories shows that atmospheric CO_2 and CH_4 at LFS are influenced by anthropogenic emissions from the southwest(Changchun and Jilin city) all year. The synoptic scale variations indicate that the northeastern China plain acts as an important source of atmospheric CO_2 and CH_4 in winter. | FANG ShuangXi Pieter P.TANS YAO Bo LUAN Tian WU YanLing YU DaJiang | 2017 | Science China Earth Sciences2017，60，10： | 16 |
| 5 | Comparative Transcriptional Profiling and Preliminary Study on Heterosis Mechanism of Super-Hybrid Rice显示文摘杂种优势比也是从二父母表演的后代改善了的生物现象和优异性能生来的父母线。混合米饭是在利用杂种优势的庄稼的最成功的 apotheoses 之一。由基因表示(半自动地面防空系统)的连续分析 F1 超级混血儿的米饭 Liangyou-2186 和它的父母介绍的 Transcriptional 表明 1183 差别表示了基因( DG ),在哪个之中 DG 被发现显著地在象光合作用和碳固定那样的小径充实,并且大多数涉及碳固定小径的关键基因在 F1 混合米饭展出了起来调整的表示。而且,相应的酶的增加的分解代谢的活动和光合的效率也被检测,它联合了显示那碳固定可能在 F1 混血儿,和力量被提高在超级混血儿的米饭与收益活力和杂种优势被联系。由有收益相关的量的特点 loci (QTL ) 的相关 DG,在微分基因表示和 phenotypic 变化之间的一种潜在的关系也被发现。另外,当以前在 Arabidopsis 报导了,包含生理节奏节奏、轻的发信号的小径的一个规章的网络也被发现,它建议如此的一个网络可能也与在混合米饭的杂种优势是相关的。总的来说,现在的学习为理解在米饭位于杂种优势下面的分子的机制提供另一个看法。 | Gui-Sheng Song Hong-Li Zhai Yong-Gang Peng Lei Zhang Gang Wei Xiao- Ying Chen Yu-Guo Xiao Lili Wang Yue-Jun Chen Bin Wu Bin Chen Yu Zhang Hua Chen Xiu-Jing Feng Wan-Kui Gong Yao Liu Zhi-Jie Yin Feng Wang Guo-Zhen Liu Hong-Lin Xu Xiao-Li Wei Xiao-Ling Zhao Pieter B.F. Ouwerkerk Thomas Hankemeier Theo Reijmers Rob van der Heijden Cong-Ming Lu Mei Wang Jan van der Greef Zhen Zhu | 2010 | Molecular Plant2010，3，6： | 12 |
| 6 | 医院筹资研究概述显示文摘目的 了解经济转型时期各类医院筹资结构及其效果的变化情况。方法 采用抽样及回顾性调查方法 ,对山东和河南两省 4 5所医院的资金运作情况及效率绩效进行调查分析。结果 1987~1999年 ,4 5所医院其政府补助占总收入的比例呈下降趋势 ,县级以上医院平均由 2 4 7%下降为8 0 % ;而病人付费和药品收入所占比例增加。同时 ,4 5所医院的生产率和社会效率均呈下降趋势 ,除乡卫生院外 ,其他三类医院的经济活力均得到增强。结论 病人付费和药品收入已成为医院筹资来源的主渠道。在注重经济效益的同时 ,应适当调整卫生政策 ,提高医院的生产率及卫生服务的社会效率。 | 徐凌中 Ian Forbes 刘兴柱 董树山 曲江斌 王健 孟庆跃 Pieter Degeling 张凯 朱洪彪 王仲阳 邴媛媛 王兴洲 王桂林 黄思桂 刘冬梅 王义伟 | 2002 | 中华医院管理杂志2002，18，7： | 12 |
| 7 | A pan-cancer blueprint of the heterogeneous tumor microenvironment revealed by single-cell profiling显示文摘The stromal compartment of the tumor microenvironment consists of a heterogeneous set of tissue-resident and tumor-infiltrating cells,which are profoundly moulded by cancer cells.An outstanding question is to what extent this heterogeneity is similar between cancers affecting different organs.Here,we profile 233,591 single cells from patients with lung,colorectal,ovary and breast cancer(n=36)and construct a pan-cancer blueprint of stromal cell heterogeneity using different single-cell RNA and protein-based technologies.We identify 68 stromal cell populations,of which 46 are shared between cancer types and 22 are unique.We also characterise each population phenotypically by highlighting its marker genes,transcription factors,metabolic activities and tissue-specific expression differences.Resident cell types are characterised by substantial tissue specificity,while tumor-infiltrating cell types are largely shared across cancer types.Finally,by applying the blueprint to melanoma tumors treated with checkpoint immunotherapy and identifying a naive CD4+T-cell phenotype predictive of response to checkpoint immunotherapy,we illustrate how it can serve as a guide to interpret scRNA-seq data.In conclusion,by providing a comprehensive blueprint through an interactive web server,we generate the first panoramic view on the shared complexity of stromal cells in different cancers. | Junbin Qian Siel Olbrecht Bram Boeckx Hanne Vos Damya Laoui Emre Etlioglu Els Wauters Valentina Pomella Sara Verbandt Pieter Busschaert Ayse Bassez Amelie Franken Marlies Vanden Bempt Jieyi Xiong Birgit Weynand Yannick van Herck Asier Antoranz Francesca Maria Bosisio Bernard Thienpont Giuseppe Floris Ignace Vergote Ann Smeets Sabine Tejpar Diether Lambrechts | 2020 | Cell Research2020，30，9： | 11 |
| 8 | A Transgenic Study on Affecting Potato Tuber Yield by Expressing the Rice Sucrose Transporter Genes OsSUT5Z and OsSUT2M显示文摘在许多植物,蔗糖 transporters 为从来源和进口的两个蔗糖出口是必要的进水池,显示功能在吸收划分。为了调查蔗糖 transporters 是否能改进淀粉的收益,种,土豆植物(茄属 tuberosum L。cv。 | Aijun Sun Yan Dai Xinsheng Zhang Chunmin Li Kun Meng Honglin Xu Xiaoli Wei Guifang Xiao Pieter B.F, Ouwerkerk Mei Wang Zhen Zhu | 2011 | Journal of Integrative Plant Biology2011，53，7： | 9 |
| 9 | Artificial Intelligence in Steam Cracking Modeling: A Deep Learning Algorithm for Detailed Effluent Prediction显示文摘Chemical processes can bene t tremendously from fast and accurate ef uent composition prediction for plant design, control, and optimization. The Industry 4.0 revolution claims that by introducing machine learning into these elds, substantial economic and environmental gains can be achieved. The bottleneck for high-frequency optimization and process control is often the time necessary to perform the required detailed analyses of, for example, feed and product. To resolve these issues, a framework of four deep learning arti cial neural networks (DL ANNs) has been developed for the largest chemicals production process steam cracking. The proposed methodology allows both a detailed characterization of a naphtha feedstock and a detailed composition of the steam cracker ef uent to be determined, based on a limited number of commercial naphtha indices and rapidly accessible process characteristics. The detailed char- acterization of a naphtha is predicted from three points on the boiling curve and paraf ns, iso-paraf ns, ole ns, naphthenes, and aronatics (PIONA) characterization. If unavailable, the boiling points are also estimated. Even with estimated boiling points, the developed DL ANN outperforms several established methods such as maximization of Shannon entropy and traditional ANNs. For feedstock reconstruction, a mean absolute error (MAE) of 0.3 wt% is achieved on the test set, while the MAE of the ef uent predic- tion is 0.1 wt%. When combining all networks using the output of the previous as input to the next the ef uent MAE increases to 0.19 wt%. In addition to the high accuracy of the networks, a major bene t is the negligible computational cost required to obtain the predictions. On a standard Intel i7 processor, predictions are made in the order of milliseconds. Commercial software such as COILSIM1D performs slightly better in terms of accuracy, but the required central processing unit time per reaction is in the order of seconds. This tremendous speed-up and minimal accuracy loss make the presented framework highly suitable for the continuous monitoring of dif cult-to-access process parameters and for the envi- sioned, high-frequency real-time optimization (RTO) strategy or process control. Nevertheless, the lack of a fundamental basis implies that fundamental understanding is almost completely lost, which is not always well-accepted by the engineering community. In addition, the performance of the developed net- works drops signi cantly for naphthas that are highly dissimilar to those in the training set. | Pieter PPlehiers Steffen HSymoens Ismaël Amghizar Guy B.Marin Christian V.Stevens Kevin M.Van Geem | 2019 | Engineering2019，5，6： | 9 |
| 10 | Acute compartment syndrome of the thigh following hip replacement by anterior approach in a patient using oral anticoagulants显示文摘Acute compartment syndrome(ACS) of the thigh following primary total hip arthroplasty(THA) is a highly uncommon complication and has not yet been reported before with regards to the anterior approach through the anterior supine interval. We present a case of a 69-year-old male patient with a history of stroke, who developed ACS of the thigh after elective THA while using therapeutic low molecular weight heparin as bridging for regular oral anticoagulation. ACS pathogenesis, diagnostic tools, treatment and relevant literature are discussed. The patient's ACS was recognized in time and treated by operative decompression with fasciotomy of the anterior compartment. Follow-up did not show any neurological deficit or soft-tissue damage. | Dirk Pieter Hogerzeil Imraan Muradin Eline W Zwitser Joris A Jansen | 2017 | World Journal of Orthopedics2017，8，12： | 8 |
| 11 | 市场经济体制下医院筹资结构的变化显示文摘 | 曲江斌 于成浩 邴媛媛 Pieter Degeling 王健 王兴洲 王义伟 | 2002 | 中华医院管理杂志2002，18，7： | 8 |
| 12 | Silicon and silicon nitride photonic circuits for spectroscopic sensing on-a-chip [Invited]显示文摘There is a rapidly growing demand to use silicon and silicon nitride(Si3N4) integrated photonics for sensing applications, ranging from refractive index to spectroscopic sensing. By making use of advanced CMOS technology,complex miniaturized circuits can be easily realized on a large scale and at a low cost covering visible to mid-IR wavelengths. In this paper we present our recent work on the development of silicon and Si3N4-based photonic integrated circuits for various spectroscopic sensing applications. We report our findings on waveguide-based absorption, and Raman and surface enhanced Raman spectroscopy. Finally we report on-chip spectrometers and on-chip broadband light sources covering very near-IR to mid-IR wavelengths to realize fully integrated spectroscopic systems on a chip. | Ananth Z.Subramanian Eva Ryckeboer Ashim Dhakal Frédéric Peyskens Aditya Malik Bart Kuyken Haolan Zhao Shibnath Pathak Alfonso Ruocco Andreas De Groote Pieter Wuytens Daan Martens Francois Leo Weiqiang Xie Utsav Deepak Dave Muhammad Muneeb Pol Van Dorpe Joris Van Campenhout Wim Bogaerts Peter Bienstman Nicolas Le Thomas Dries Van Thourhout Zeger Hens Gunther Roelkens Roel Baets | 2015 | Photonics Research2015，3，5： | 7 |
| 13 | Single nucleotide polymorphism in the tumor necrosis factor-alpha gene affects inflammatory bowel diseases risk显示文摘AIM: To investigate the role that single nucleotide polymorphisms (SNPs) in the promoter of the tumour necrosis factor-alpha (TNF-α) gene play in the risk of inflammatory bowel diseases (IBDs) in a New Zealand population, in the context of international studies. METHODS: DNA samples from 388 patients with Crohn's disease (CD), 405 ulcerative colitis (UC), 27 indeterminate colitis (IC) and 201 randomly selected controls, from Canterbury, New Zealand were screened for 3 common polymorphisms in the TNF-α receptor: -238 G→A, -308 G→A and -857C→T, using a TaqmanR assay. A meta-analysis was performed on the data obtained on these polymorphisms combined with that from other published studies. RESULTS: Individuals carrying the -308 G/A allele had a significantly (OR = 1.91, χ2 = 17.36, P < 0.0001) increased risk of pancolitis, and a 1.57-fold increased risk (OR = 1.57, χ2 = 4.34, P = 0.037) of requiring a bowel resection in UC. Carrying the -857 C/T variant decreased the risk of ileocolonic CD (OR = 0.56, χ2 =4.32, P = 0.037), and the need for a bowel resection (OR = 0.59, χ2 = 4.85, P = 0.028). The risk of UC was reduced in individuals who were smokers at diagnosis, (OR = 0.48, χ2 = 4.86, P = 0.028). CONCLUSION: TNF-α is a key cytokine known to play a role in inflammatory response, and the locus for the gene is found in the IBD3 region on chromosome 6p21, known to be associated with an increased risk for IBD. The -308 G/A SNP in the TNF-α promoter is functional, and may account in part for the increased UC risk associated with the IBD3 genomic region. The -857 C/T SNP may decrease IBD risk in certain groups. Pharmaco- or nutrigenomic approaches may be desir- able for individuals with such affected genotypes. | Lynnette R Ferguson Claudia Huebner Ivonne Petermann Richard B Gearry Murray L Barclay Pieter Demmers Alan McCulloch Dug Yeo Han | 2008 | World Journal of Gastroenterology2008，14，29： | 7 |
| 14 | Laparoscopic total gastrectomy versus open total gastrectomy for cancer: a systematic review and meta-analysis显示文摘 | Leonie Haverkamp Teus J. Weijs Pieter C. Sluis Ingeborg Tweel Jelle P. Ruurda Richard Hillegersberg | 2013 | Surgical Endoscopy2013，，5： | 6 |
| 15 | 大数据时代的交通模型显示文摘通过新的大数据来源诸如手机通信记录、智能卡数据以及社交媒体地理编码记录,可以前所未有地观察和了解出行行为的细节。尽管有如此庞大的大数据来源,但在规划实践中使用的交通需求模型,其数据源仍大多来自交通调查和人口普查等传统方法。对近期利用大数据研究交通行为,以及使交通规划师可以进行假设情景分析的交通需求模型的最新进展进行梳理。从出行识别到出行活动推理,回顾和分析现有数据分析方法,这些传统方法使收集到的出行轨迹信息能响应交通需求模型。未来的研究应该侧重将概率模型和机器学习技术应用于数据科学。设计这些数据挖掘方法是为了处理由手机移动追踪数据衍生的零散和掺杂偏差的数据的不确定性。此外,这些方法还适用于将不同的相关数据组整合到一个数据融合方案中,以便用出行日志信息丰富大数据。总之,建模知识已经在交通运输领域发展成熟,因此强烈建议在交通规划方面应用数据驱动方法时应建立相应领域专业知识的基础。这些新的挑战呼吁交通模型师和数据科学家之间的多学科协作。 | Cuauhtemoc Anda Alexander Erath Pieter Jacobus Fourie(著) 宗晶(译) | 2019 | 城市交通2019，17，3： | 5 |
| 16 | Magnetic resonance spectroscopy to study hepatic metabolism in diffuse liver diseases, diabetes and cancer显示文摘This review provides an overview of the current state of the art of magnetic resonance spectroscopy (MRS) in in vivo investigations of diffuse liver disease. So far, MRS of the human liver in vivo has mainly been used as a research tool rather than a clinical tool. The liver is particularly suitable for static and dynamic metabolic studies due to its high metabolic activity. Furthermore, its relatively superfi cial position allows excellent MRS localization, while its large volume allows detection of signals with relatively low intensity. This review describes the application of MRS to study the metabolic consequences of different conditions including diffuse and chronic liver diseases, congenital diseases, diabetes, and the presence of a distant malignancy on hepatic metabolism. In addition, future prospects of MRS are discussed. It is anticipated that future technical developments such as clinical MRS magnets with higher fi eld strength (3 T) and improved delineation of multicomponent signals such as phosphomonoester and phosphodiester using proton decoupling, especially if combined with price reductions for stable isotope tracers, will lead to intensifi ed research into metabolic syndrome, cardiovascular disease, hepato-biliary diseases, as well as non-metastatic liver metabolism in patients with a distant malignant tumor. | Pieter C Dagnelie Susanne Leij-Halfwerk | 2010 | World Journal of Gastroenterology2010，16，13： | 5 |
| 17 | Current status of assessment of fractional flow reserve显示文摘 | FANG Yi-min Grisana Grootenhuijs-Triyasut Pieter A. Doevendans Yolande Appelman | 2009 | Chinese Medical Journal2009，，6： | 5 |
| 18 | Effects of Annealing Treatments on Luminescence and Scintillation Properties of Ce:Lu_3Al_5O_(12) Crystal Grown by Czochralski Method显示文摘Ce:Lu3Al5O12 single crystals grown in pure N2 atmosphere by Czochralski method were annealed in oxidizing atmosphere (air) and reducing atmosphere (H2+N2), respectively. Effects of annealing treatments on luminescence and scintillation properties of the crystals were investigated. The crystal annealed in air showed the highest luminescence intensity under blue light or vacuum ultraviolet excitation in comparison with that annealed in reducing flux or the as-grown crystal. Under X-ray excitation, crystal annealed in reducing atmosphere had the lowest light yield, and crystal annealed in air had the fastest decay time under 137Cs 662 keV γ-ray excitation. Different annealing treatments resulted in different luminescence and scintillation properties, which might related with oxygen vacancies or defect existing in the crystals. | 钟玖平 梁宏斌 苏锵 张国斌 Dorenbos Pieter Birowosuto Muhammad Danang | 2007 | Journal of Rare Earths2007，25，5： | 4 |
| 19 | CPB的冠脉手术病人主要麻醉方法的选择影响术后ICU住院时间显示文摘 | Stefan G.De Hert Philippe J.Van der Linden Stefanie Cromheecke Roel Meeus Pieter W.ten Broecke Ivo G.De Blier Bernard A.tockman Inez E.Rodrigus 刘功俭(译) 曾因明(审) | 2004 | 国外医学(麻醉学与复苏分册)2004，25，4： | 4 |
| 20 | Endoscopic ultrasound-guided drainage of the biliary system:Techniques,indications and future perspectives显示文摘Over the last decade, endoscopic ultrasound-guided biliary drainage(EUS-BD)has evolved into a widely accepted alternative to the percutaneous approach in cases of biliary obstruction with failed endoscopic retrograde cholangiopancreaticography(ERCP). The available evidence suggests that, in experienced hands, EUS-BD might even replace ERCP as the first-line procedure in specific situations such as malignant distal bile duct obstruction. The aim of this review is to summarize the available data on EUS-BD and propose an evidence-based algorithm clarifies the role of the different EUS-BD techniques in the management of benign and malignant biliary obstructive disease. | Pieter Hindryckx Helena Degroote David J Tate Pierre H Deprez | 2019 | World Journal of Gastrointestinal Endoscopy2019，11，2： | 4 |
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