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| 1 | Successful photodynamic therapy for biliary papillomatosis:A case report显示文摘Papillomatosis of the bile duct is a rare disease with a high risk of malignant transformation. Therapeutical options include partial hepatectomy and liver transplantation. A previously healthy 65-years old male developed jaundice and right upper abdominal quadrant pain in 1996. A villous adenoma of the distal bile duct was diagnosed. A Whipple procedure was performed. In 2002 the patient turned symptomatic again. Another adenoma was found in the right hepatic duct resulting in a right hepatectomy. Two years later the patient again developed cholestasis. After drainage of the left hepatic duct with a percutaneous transhepatic cholangial drainage (PTCD) catheter, a recurrent biliary adenomatosis was diagnosed by cholangioscopy. As there was no surgical option left, the patient received photodynamic therapy (PDT) for the recurrent biliary papillomatosis. Three mo after he received further photodynamic therapies, the bile duct epithelium appeared normal and the patient had no signs of adenomatosis, both macroscopically and histologically. The follow-up cholangioscopy in late 2005 revealed only a small papilloma without the need for intervention. In early 2006, the patient died of multi organ failure without signs of extrahepatic cholestasis or cholangitis at the age of 75, 10 years after the diagnosis of biliary papillomatosis was established. The patient exceeded the average life expectancy of patients with biliary papillomatosis by far. Thus, PDT might be a sufficient therapeutic option for recurrent papillomatosis patients with no significant side effects. | Lars P Bechmann Philip Hilgard Andrea Frilling Brigitte Schumacher Hideo A Baba Guido Gerken Thomas Zoepf | 2008 | World Journal of Gastroenterology2008,14,26: | 7 |
| 2 | 如何设计高质量针刺临床研究:基于证据的专家共识显示文摘本针刺随机对照试验(Randomised controlled trials, RCT)专家共识是基于目前针刺试验面临的最普遍、最关键问题,由临床医生、研究人员、从事针灸和外科的临床试验专家、统计专家、临床流行病学和方法学专家以及患者组成的国际临床研究小组联合制订。该共识将有助于临床试验资助者、注册者以及期刊编辑等评估针刺RCT方案及研究结果的相关性、重要性和质量。 | 张誉清 焦睿珉 Claudia M Witt 劳力行 刘建平 Lehana Thabane Karen J Sherman Mike Cummings Dawn P Richards Eun-Kyung Anna Kim Tae-Hun Kim Myeong Soo Lee Michael E Wechsler Benno Brinkhaus Jun J Mao Caroline A Smith 岗卫娟 刘保延 刘志顺 刘岩 郑晖 吴佳霓 AloBSO Carrasco-Labra Mohit Bhandari Philip J Devereaux 景向红 Gordon Guyatt | 2022 | 英国医学杂志中文版2022,25,6: | 7 |
| 3 | Risk stratification for ST segment elevation myocardial infarction in the era of primary percutaneous coronary intervention显示文摘Acute coronary syndromes presenting with ST elevation are usually treated with emergency reperfusion/revascularisation therapy. In contrast current evidence and national guidelines recommend risk stratification for non ST segment elevation myocardial infarction(NSTEMI) with the decision on revascularisation dependent on perceived clinical risk. Risk stratification for STEMI has no recommendation. Statistical risk scoring techniques in NSTEMI have been demonstrated to improve outcomes however their uptake has been poor perhaps due to questions over their discrimination and concern for application to individuals who may not have been adequately represented in clinical trials. STEMI is perceived to carry sufficient risk to warrant emergency coronary intervention [by primary percutaneous coronary intervention(PPCI)] even if this results in a delay to reperfusion with immediate thrombolysis. Immediate thrombolysis may be as effective in patients presenting early, or at low risk, but physicians are poor at assessing clinical and procedural risks and currently are not required to consider this. Inadequate data on risk stratification in STEMI inhibits the option of immediate fibrinolysis, which may be cost-effective. Currently the mode of reperfusion for STEMI defaults to emergency angiography and percutaneous coronary intervention ignoring alternative strategies. This review article examines the current risk scores and evidence base for risk stratification for STEMI patients. The requirements for an ideal STEMI risk score are discussed. | Richard A Brogan Christopher J Malkin Philip D Batin Alexander D Simms James M McLenachan Christopher P Gale | 2014 | World Journal of Cardiology2014,6,8: | 6 |
| 4 | Impaired CTLA-4 responses in COPD are associated with systemic inflammation显示文摘 | Dino BA Tan Sonia Fernandez PatriciaPrice Martyn A French Philip J Thompson Yuben P Moodley | 2014 | Cellular & Molecular Immunology2014,11,6: | 3 |
| 5 | Formanilide and carbanilide from aniline and carbon dioxide 显示文摘 | Munshi Pradip Heldebrant David J McKoon Erin P Kelly Patrick A Tai Chih-Cheng Jessop Philip G | 2003 | Tetrahedron Letters2003,44,: | 1 |
| 6 | Time series sales forecas- ting for short shelf-life food products based on artificial neural networks and evolutionary computing显示文摘 | Philip D Alex A Panagiotis P | | 0,,75: | 1 |
| 7 | RF-based partial discharge early warning system for air insulated substations显示文摘 | Iliana E P Philip J M Ian A G | 2009 | IEEE Transactons on Power Delivery2009,24,1: | 1 |
| 8 | An introduction toevaluating biometric systems显示文摘 | Philips P J martin A Wilson C L | | Computer0,32,2: | 1 |
| 9 | RF-based partial dis- charge early waring system for air-insulated substations显示文摘 | Iliana E P Philip J M Ian A G | 2009 | IEEE Trans on Power Delivery2009,24,1: | 1 |
| 10 | Nucleotide sequence of the 5′-terminus of Newcastle disease virus and assembly of the complete genomic sequence: agreement with the “rule of six”显示文摘 | Philips R J Samson A C R Emmerson P T | 1998 | Arch Virol1998,143,: | 1 |
| 11 | Consensus re port of the national cancer institute clinical trials planning meeting on pancreas cancer treatment显示文摘 | PHILIP P A MOONEY M JAFFE D | 2009 | Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology2009,27,33: | 1 |
| 12 | Forkhead transcription factors coordinate expression of myocardial KATP channel subunits and energy metabolism显示文摘 | Philip Couderc P Tavares N I Roatti A | 2008 | Circ Res2008,102,2: | 1 |
| 13 | SYN-1012:A new β-actamase inhibitor of penem skeleton显示文摘 | David P Czalkowski Paul Spevak | 1997 | J Antibiotics1997,50,4: | 1 |
| 14 | Analysis of Volatile Organic Compounds in Estuarine Sediments Using Dynamic Headspace and Gas Chromatography-mass Spectrometry显示文摘 | Bianchi A P Varney M S Philips J | 1991 | J Chrornatogr A1991,542,: | 1 |
| 15 | A comparative study of laser induced breakdown spectroscopy analysis for element concentration in aluminum alloy using atificial neural networks and calibration methods显示文摘 | Inakollu P Philip T Rai A K | 2009 | Spectrochimica Acta Part B2009,64,1: | 1 |
| 16 | Phase Ⅱ study of erlotinib in patients with advanced biliary cancer 显示文摘 | Philip P A Mahoney M R Allmer C | 2006 | J Clin Oncol2006,24,19: | 1 |
| 17 | Prevention and control of cystic echinococcosis显示文摘 | Philip S Craig Donald P McManus Marshall W Lightowlers Jose A Chabalgoity Hector H Garcia Cesar M Gavidia Robert H Gilman Armando E Gonzalez Myriam Lorca Cesar Naquira Alberto Nieto Peter M Schantz | 2007 | The Lancet Infectious Diseases2007,,6: | 1 |
| 18 | Phase I study of bryostatin I: assessment of interleukin 6 and tumor necrosis factor alpha induction in vivo 显示文摘 | Rea D Thavasu P | 1993 | J Natl Cancer Inst1993,85,22: | 1 |
| 19 | Has combined modality therapy improved the outlook in carcinoma of the esophagus 显示文摘 | Philip P A Ajani J A | 1994 | Oncology (Williston Park)1994,8,9: | 1 |
| 20 | Differential effect of Rac and Cdc42 on p38 kinase activity and cell cycle progression of nonadherent primary mouse fibroblasts显示文摘 | Philips A Roux P Coulon V | 2000 | J Biol Chem2000,275,8: | 1 |